Abstract:
BACKGROUND:This paper studies the effect of mosquito abundance and malaria incidence in the last 3 weeks, and their interaction, on the hazard of time to malaria in a previously studied cohort of children in Ethiopia. METHODS:We model the mosquito abundance and time to malaria data jointly in a Bayesian framework. RESULTS:We found that the interaction of mosquito abundance and incidence plays a prominent role on malaria risk. We quantify and compare relative risks of various factors, and determine the predominant role of the interaction between incidence and mosquito abundance in describing malaria risk. Seasonal rain patterns, distance to a water source of the households, temperature and relative humidity are all significant in explaining mosquito abundance, and through this affect malaria risk. CONCLUSION:Analyzing jointly the time to malaria data and the mosquito abundance allows a precise comparison of factors affecting the spread of malaria. The effect of the interaction between mosquito abundances and local presence of malaria parasites has an important effect on the hazard of time to malaria, beyond abundance alone. Each additional one km away from the dam gives an average reduction of malaria relative risk of 5.7%. The importance of the interaction between abundance and incidence leads to the hypothesis that preventive intervention could advantageously target the infectious population, in addition to mosquito control, which is the typical intervention today.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Belay DB,Kifle YG,Goshu AT,Gran JM,Yewhalaw D,Duchateau L,Frigessi Adoi
10.1186/s12879-017-2496-4subject
Has Abstractpub_date
2017-06-12 00:00:00pages
415issue
1issn
1471-2334pii
10.1186/s12879-017-2496-4journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Non-organ-specific autoantibodies are found in a considerable number of anti-HCV positive patients. Previous studies investigated the clinical relevance of these antibodies in patients treated with interferon monotherapy, but not combination therapies. METHODS:Anti-nuclear, anti-smooth muscle, anti-mitochon...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-4-4
更新日期:2004-02-13 00:00:00
abstract:BACKGROUND:Erythema induratum of Bazin (EIB) - nodular vasculitis associated with Mycobacterium tuberculosis (TB) - and Tuberculosis-Associated Ocular Inflammation (TB-AOI) represent uncommon manifestations of TB. There is limited data and a lack of diagnostic and treatment standards for these conditions. METHODS:Elev...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-3737-5
更新日期:2019-01-29 00:00:00
abstract:BACKGROUND:Pertussis causes severe disease in young unvaccinated infants, with preterms potentially at highest risk. We studied pertussis in hospitalized infants as related to gestational age (GA) and vaccination history. METHODS:Medical record data of 0-2y old patients hospitalized for pertussis during 2005-2014 were...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4563-5
更新日期:2019-10-29 00:00:00
abstract:BACKGROUND:Prion diseases are caused by the accumulation of an aberrantly folded isoform of the prion protein, designated PrPSc. In a cell-based assay, quinacrine inhibits the conversion of normal host prion protein (PrPC) to PrPSc at a half-maximal concentration of 300 nM. While these data suggest that quinacrine may ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-4-53
更新日期:2004-11-29 00:00:00
abstract:BACKGROUND:This multicenter study describes the type-specific prevalence of HPV infection in the general population from central and southern Italy, comparing the data with previously published Italian studies. METHODS:Women aged from 25 to 65 who attended cervical cancer screening in five different Italian regions we...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2334-10-214
更新日期:2010-07-20 00:00:00
abstract:BACKGROUND:In Finland, the annual number of MRSA notifications to the National Infectious Disease Register (NIDR) has constantly increased since 1995, and molecular typing has revealed numerous outbreak isolates of MRSA. We analyzed the data on MRSA notifications of the NIDR, and MRSA isolates were identified mainly by...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-7-94
更新日期:2007-08-14 00:00:00
abstract:BACKGROUND:Visceral disseminated varicella zoster virus (VDVZV) infection is a rare disease with a high mortality rate (55%) in immunocompromised patients, but it is not yet widely recognized in the field of nephrology. We report a case of VDVZV contracted during immunosuppressive therapy for membranous nephropathy. C...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4193-y
更新日期:2019-07-15 00:00:00
abstract:BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) represent an important global threat. The aim of this study is to describe the clinical course and outcomes of patients with CRE infections treated with ceftazidime-avibactam (CAZ-AVI) compared to patients treated with other agents. METHODS:A retrospective cohor...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4409-1
更新日期:2019-09-04 00:00:00
abstract:BACKGROUND/AIM:Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common multidrug-resistant organisms in healthcare settings worldwide, but little is known about MRSA transmission outside of acute healthcare settings especially in Asia. We describe the methods for a prospective longitudinal study of...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-017-2793-y
更新日期:2017-10-11 00:00:00
abstract:BACKGROUND:There currently is a severe Zika Virus (ZIKV) epidemic in Brazil and other South American countries. Due to international travel, this poses severe public health risk of ZIKV importation to other countries. We estimate the prevalence of ZIKV in an import region by the time a microcephaly case is detected, si...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-2076-z
更新日期:2016-12-12 00:00:00
abstract:BACKGROUND:Previously thought to be rabies free, Bali experienced an outbreak of animal and human rabies cases in November 2008. We describe the epidemiological and clinical data of human rabies cases occurring in the first two years of the outbreak. METHODS:We analysed the patient records of all rabies cases from the...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-12-81
更新日期:2012-04-02 00:00:00
abstract:BACKGROUND:Rapid influenza diagnosis is important for early identification of outbreaks, effective management of high-risk contacts, appropriate antiviral use, decreased inappropriate antibiotic use and avoidance of unnecessary laboratory testing. Given the inconsistent performance of many rapid influenza tests, clinic...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-12-129
更新日期:2012-06-07 00:00:00
abstract:BACKGROUND:Saksenaea species (spp.) are uncommon causes of mucormycosis but are emerging pathogens mostly associated with trauma and soil contamination often in immunocompetent hosts. Due to lack of sporulation in the laboratory, diagnosis and susceptibility testing is difficult so optimal treatment regimens are unknow...
journal_title:BMC infectious diseases
pub_type: 杂志文章,评审
doi:10.1186/s12879-020-05459-9
更新日期:2020-10-14 00:00:00
abstract:BACKGROUND:Information about improvements in the health status of population at-risk of helminth infection after anthelminthic treatment helps to evaluate the effectiveness of the large scale deworming program. The objectives of this study were to assess the impact of anthelminthic treatment on the prevalence and inten...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1956-6
更新日期:2016-10-28 00:00:00
abstract:BACKGROUND:At the end of the 1970s, in Italy more than 2% of the general population was HBsAg carrier. In the late '70s and late '80s, two remarkable events might have impacted on HBV strains transmitted in North-East Italy: (a) the increased HBV incidence due to parenteral drugs between 1978 and 1982; (b) the preventi...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4713-9
更新日期:2020-01-28 00:00:00
abstract:BACKGROUND:Diagnostic tests are generally used in situations with similar pre-test probability of disease to where they were developed. When these tests are applied in situations with very different pre-test probabilities of disease, it is informative to model the likely implications of known characteristics of test pe...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-93
更新日期:2010-04-12 00:00:00
abstract:BACKGROUND:The management of disseminated cysticercosis is unclear and largely considered hazardous. The role of albendazole remains controversial in such patients. METHODS:A tertiary care, University hospital-based prospective intervention study was conducted from December 2015 to December 2017. Patients with dissemi...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-4891-5
更新日期:2020-03-14 00:00:00
abstract:BACKGROUND:While the prevalence of multidrug-resistant (MDR) tuberculosis (TB) is high among children in the Western Cape of South Africa, the psychosocial implications of treatment for children with MDR-TB remain poorly understood. We sought to explore how MDR-TB and its treatment impact children on an individual, fam...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-14-426
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Acute respiratory tract infections (ARTI) are an important public health problem. Improved identification of risk factors might enable targeted intervention. Therefore we carried out a case-control study with the aim of identifying environmental risk factors for ARTI consultations in the Dutch general popula...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-7-35
更新日期:2007-04-27 00:00:00
abstract:BACKGROUND:Middle East Respiratory Syndrome (MERS) is caused by MERS coronavirus (MERS-CoV). More than 80% of reported cases have occurred in Saudi Arabia, with a mortality exceeding 50%. Health-care workers (HCWs) are at risk of acquiring and transmitting this virus, so the concerns of HCWs in Saudi Arabia regarding M...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-2096-8
更新日期:2017-01-03 00:00:00
abstract:BACKGROUND:Influenza disease burden varies by age and this has important public health implications. We compared the proportional distribution of different influenza virus types within age strata using surveillance data from twenty-nine countries during 1999-2014 (N=358,796 influenza cases). METHODS:For each virus, we...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3181-y
更新日期:2018-06-08 00:00:00
abstract:BACKGROUND:Severe infection is a main cause of mortality. We aim to describe risk factors for long-term mortality among inpatients with severe infection. METHODS:Prospective cohort study in a 600-bed university hospital in Portugal including all patients with severe infection admitted into intensive care, medical, sur...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3054-4
更新日期:2018-04-05 00:00:00
abstract:BACKGROUND:Molecular diagnostics have emerged as an efficient and feasible alternative for broad detection of pathogens in faeces. However, collection of stool samples is often impractical in both clinical work and in epidemiology studies. The aim of this study was to investigate the diagnostic performance of rectal sw...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-447
更新日期:2013-09-27 00:00:00
abstract:BACKGROUND:Varicella is a common childhood disease. Only 5% of first varicella-zoster-virus infections occur asymptomatically. Most data on the burden of varicella stem from health service databases. This study aims to provide insight in the burden of varicella from a parent's perspective including cases outside the he...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-11-320
更新日期:2011-11-17 00:00:00
abstract:BACKGROUND:Clostridium difficile infection (CDI), a complication of antibiotic-induced injury to the gut microbiome, is a prevalent and dangerous cause of infectious diarrhea. Antimicrobial therapy for CDI is typically effective for acute symptoms, but up to one third of patients later experience recurrent CDI. Fecal-d...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-0930-z
更新日期:2015-04-17 00:00:00
abstract:BACKGROUND:This retrospective study evaluated the performance of a lipoarabinomannan (LAM)-based immunological method for diagnosing pleural tuberculosis (TB) from pleural effusion samples. Results were compared to those obtained using conventional culture and molecular testing methods. METHODS:Suspected pleural TB pa...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4166-1
更新日期:2019-06-21 00:00:00
abstract:BACKGROUND:Haemophilus influenzae type b (Hib) vaccination led to a significant decrease in invasive bacterial infections in children. The aim of this study was to assess a potential shift to more non-type b invasive infections in a population with high Hib vaccination coverage and to compare the burden of suffering be...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-45
更新日期:2009-04-20 00:00:00
abstract:BACKGROUND:Prisoners represent a vulnerable population for blood-borne and sexually transmitted infections which can potentially lead to liver fibrosis and ultimately cirrhosis. However, little is known about the prevalence of liver fibrosis and associated risk factors among inmates in sub-Saharan Africa. METHODS:Scre...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1601-4
更新日期:2016-06-06 00:00:00
abstract:BACKGROUND:Comparison of antimicrobial de-escalation rates between healthcare settings is problematic. To objectively and electronically measure de-escalation a method based upon the spectrum of antimicrobial regimens administered (i.e., spectrum score) was developed. METHODS:A Delphi process was used to develop appli...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-0933-9
更新日期:2015-04-25 00:00:00
abstract:BACKGROUND:Myocarditis can develop as a complication of various infections and is most commonly linked to enterovirus infections. Myocarditis is rarely associated with bacterial infections; salmonellosis and shigellosis have been the most frequently reported bacterial cause. We report a case of myocarditis related to C...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-3-16
更新日期:2003-07-17 00:00:00