Pharmacokinetics of quinacrine in the treatment of prion disease.

abstract：BACKGROUND:A rare phenotype of clinical non-progressors to AIDS is not well understood and the new protocol for universal treatment, may block the understanding of viral control thus it is crucial to define this controversial group. METHODS:A cohort of 30 persons followed a criteria for viremia control groups 1 (VC1; ...

journal_title：BMC infectious diseases

authors： Gomes STM,Gomes ÉR,Dos Santos MB,Lima SS,Queiroz MAF,Machado LFA,Cayres-Vallinoto IMV,Vallinoto ACR,de O Guimarães Ishak M,Ishak R

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Among septic patients admitted to the intensive care unit (ICU), early recognition of those with the highest risk of death is of paramount importance. Since clinical judgment is sometimes uncertain biomarkers could provide additional information likely to guide critical illness management. We evaluated the p...

journal_title：BMC infectious diseases

authors： Charles PE,Noel R,Massin F,Guy J,Bollaert PE,Quenot JP,Gibot S

更新日期：2016-10-12 00:00:00

abstract：BACKGROUND:International contact-tracing (CT) following exposure during long-distance air travel is resource-intensive, whereas evidence for risk of tuberculosis (TB) transmission during international travel is weak. In this study, we systematically analyzed the information from international requests for CT received a...

journal_title：BMC infectious diseases

authors： Glasauer S,Kröger S,Haas W,Perumal N

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a significant public health problem that may lead to chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC). Approximately 30% of the world's population has been infected with HBV and approximately 350 million (5-6%) are persistent carriers. More than 120 mi...

journal_title：BMC infectious diseases

authors： Zeng Z,Guan L,An P,Sun S,O'Brien SJ,Winkler CA,HBV study consortium.

更新日期：2008-01-02 00:00:00

abstract：BACKGROUND:Delay in the diagnosis of Tuberculosis (TB) remains a major challenge against achieving effective TB prevention and control. Though a number of studies with inconsistent findings were conducted in Ethiopia; unavailability of a nationwide study determining the median time of patient delays to TB diagnosis is ...

journal_title：BMC infectious diseases

authors： Alene M,Assemie MA,Yismaw L,Gedif G,Ketema DB,Gietaneh W,Chekol TD

更新日期：2020-10-27 00:00:00

abstract：BACKGROUND:In France, 1/3 HIV-infected patients is diagnosed at an advanced stage of the disease. We describe missed opportunities for earlier HIV testing in newly-HIV-diagnosed patients. METHODS:Cross sectional study. Adults living in France for ≥1 year, diagnosed with HIV-infection ≤6 months earlier, were included f...

journal_title：BMC infectious diseases

authors： Champenois K,Cousien A,Cuzin L,Le Vu S,Deuffic-Burban S,Lanoy E,Lacombe K,Patey O,Béchu P,Calvez M,Semaille C,Yazdanpanah Y

更新日期：2013-05-02 00:00:00

abstract：BACKGROUND:Acute reduction in hemoglobin levels is frequently seen during sepsis. Previous studies have focused on the management of anemia in patients with septic shock admitted to intensive care units (ICU's), including aggressive blood transfusion aiming to enhance tissue oxygenation. AIM:To study the changes in he...

journal_title：BMC infectious diseases

authors： Muady GF,Bitterman H,Laor A,Vardi M,Urin V,Ghanem-Zoubi N

更新日期：2016-10-13 00:00:00

abstract：BACKGROUND:War-wounded civilians in Middle East countries are at risk of post-traumatic osteomyelitis (PTO). We aimed to describe and compare the bacterial etiology and proportion of first-line antibiotics resistant bacteria (FLAR) among PTO cases in civilians from Syria, Iraq and Yemen admitted to the reconstructive s...

journal_title：BMC infectious diseases

authors： Fily F,Ronat JB,Malou N,Kanapathipillai R,Seguin C,Hussein N,Fakhri RM,Langendorf C

更新日期：2019-01-31 00:00:00

abstract：BACKGROUND:The role of Diabetes mellitus (DM) in the etiology and in the antimicrobial resistance of uropathogens in patients with urinary tract infection has not been well clarified. For this reason we have evaluated the spectrum of uropathogens and the profile of antibiotic resistance in both diabetic and non diabeti...

journal_title：BMC infectious diseases

authors： Bonadio M,Costarelli S,Morelli G,Tartaglia T

更新日期：2006-03-17 00:00:00

abstract：BACKGROUND:It is estimated that Lao People's Democratic Republic (Lao PDR) ranks fifth among the seven countries most affected by TB in the WHO Western Pacific Region. However, because of late implementation of mycobacterial culture, no study on resistance to anti-TB drugs had been performed yet. The objective of this ...

journal_title：BMC infectious diseases

authors： Iem V,Somphavong S,Buisson Y,Steenkeste N,Breysse F,Chomarat M,Sylavanh P,Nanthavong P,Rajoharison A,Berland JL,Paboriboune P

更新日期：2013-06-19 00:00:00

abstract：BACKGROUND:Identification of people living with HIV is key in HIV prevention and control. Partner Notification service is a World Health Organization backed strategy of reaching out to sexual partners of people diagnosed with HIV for HIV testing. However, its adoption and success rate in Kenya remains unknown. METHODS...

journal_title：BMC infectious diseases

authors： Kariuki RM,Rithaa GK,Oyugi EO,Gachathi DM

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:Seroreactivity, processes of seroconversion and seroreversion, in the context of HPV infection has been investigated in numerous studies. However, the data resulting from these studies are usually not accounted for in mathematical transmission models of various HPV types due to gaps in our understanding of t...

journal_title：BMC infectious diseases

authors： Korostil IA,Garland SM,Law MG,Regan DG

更新日期：2013-02-13 00:00:00

abstract：BACKGROUND:Due to the populations' susceptibility, DENV-4 introduction in 2010 led to the occurrence of explosive epidemics in the following years in Brazil. In 2011, DENV-4 was identified in Rio de Janeiro (RJ) and it was prevalent in 2012 and 2013. Here, we aimed to characterize clinical, epidemiological and laborato...

journal_title：BMC infectious diseases

authors： Heringer M,Souza TMA,Lima MDRQ,Nunes PCG,Faria NRDC,de Bruycker-Nogueira F,Chouin-Carneiro T,Nogueira RMR,Dos Santos FB

更新日期：2017-06-09 00:00:00

abstract：BACKGROUND:While cultivation of pathogens represents a foundational diagnostic approach in the study of infectious diseases, its value for the confirmation of clinical diagnosis of Buruli ulcer is limited by the fact that colonies of Mycobacterium ulcerans appear only after about eight weeks of incubation at 30°C. Howe...

journal_title：BMC infectious diseases

authors： Bratschi MW,Bolz M,Grize L,Kerber S,Minyem JC,Um Boock A,Yeboah-Manu D,Ruf MT,Pluschke G

更新日期：2014-11-30 00:00:00

abstract：BACKGROUND:Pertussis diagnosis may go unrecognized when other pathogens, such as respiratory syncytial virus (RSV) circulate. METHODS:A prospective cross-sectional study was conducted in Lima, Peru from January 2009 to September 2010. A total of 596 children under 5 years old admitted with clinical diagnoses of acute ...

journal_title：BMC infectious diseases

authors： Pavic-Espinoza I,Bendezú-Medina S,Herrera-Alzamora A,Weilg P,Pons MJ,Aguilar-Luis MA,Petrozzi-Helasvuo V,del Valle Mendoza J

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:The most optimal antifungal agent for empiric treatment of invasive fungal diseases (IFDs) in febrile neutropenia is controversial. Our objective was evaluate the relative efficacy of antifungals for all-cause mortality, fungal infection-related mortality and treatment response in this population. METHODS:P...

journal_title：BMC infectious diseases

authors： Chen K,Wang Q,Pleasants RA,Ge L,Liu W,Peng K,Zhai S

更新日期：2017-02-20 00:00:00

abstract：BACKGROUND:Non-touch fittings have been reported to be susceptible for Pseudomonas aeruginosa accumulation. A number of factors may contribute to this, including the frequency of usage, duration of water stagnation, or presence of plastic materials. Programmable non-touch fittings are appearing which allow regular auto...

journal_title：BMC infectious diseases

authors： Suchomel M,Diab-Elschahawi M,Kundi M,Assadian O

更新日期：2013-08-30 00:00:00

abstract：BACKGROUND:Identification of the causative agents of invasive fungal infections (IFI) is critical for guiding antifungal therapy. Cultures remain negative in a substantial number of IFI cases. Accordingly, species identification from formalin fixed, paraffin embedded (FFPE) tissue specimens by molecular methods such as...

journal_title：BMC infectious diseases

authors： Rickerts V,Khot PD,Myerson D,Ko DL,Lambrecht E,Fredricks DN

更新日期：2011-07-26 00:00:00

abstract：BACKGROUND:The increasing antimalarial drug resistance is a significant hindrance to malaria control and elimination programs. For the last six decades, chloroquine (CQ) plus pyrimethamine remains the first-line treatment for P. vivax malaria. Regions where both P. falciparum and P. vivax co-exist, P. vivax is exposed ...

journal_title：BMC infectious diseases

authors： Kaur H,Sehgal R,Kumar A,Bharti PK,Bansal D,Mohapatra PK,Mahanta J,Sultan AA

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Brucella abortus is a highly pathogenic zoonotic agent, tempting for the development of a rapid diagnostic method to enable adequate treatment and prevent further spread. Enrichment of the bacteria is often used as a first step in diagnostics to increase the bacterial number above the detection limit of the ...

journal_title：BMC infectious diseases

authors： Kaden R,Ferrari S,Jinnerot T,Lindberg M,Wahab T,Lavander M

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:HIV controllers (HICs) are a rare group of HIV-1-infected individuals able to naturally control viral replication. Several studies have identified the occurrence of HIV dual infections in seropositive individuals leading to disease progression. In HICs, however, dual infections with divergent outcomes in pat...

journal_title：BMC infectious diseases

authors： Caetano DG,Côrtes FH,Bello G,de Azevedo SSD,Hoagland B,Villela LM,Grinsztejn B,Veloso VG,Guimarães ML,Morgado MG

更新日期：2019-07-05 00:00:00

abstract：BACKGROUND:Although early presentation to HIV-care is essential to ensure timely initiation of antiretroviral therapy, recent studies have shown that especially migrants present to HIV-care at a later stage of HIV-infection. Currently, thirty percent of all newly diagnosed HIV cases in Germany originate from abroad. So...

journal_title：BMC infectious diseases

authors： Zeitlmann N,Gunsenheimer-Bartmeyer B,Santos-Hövener C,Kollan C,An der Heiden M,ClinSurv Study Group.

更新日期：2016-12-07 00:00:00

abstract：BACKGROUND:Bacterial vaginosis (BV) - a syndrome characterised by a shift in vaginal flora - appears to be particularly common in sub-Saharan Africa, but little is known of the pattern of vaginal flora associated with BV in Africa. We conducted a study aimed at determining the prevalence of BV and patterns of BV-associ...

journal_title：BMC infectious diseases

authors： Demba E,Morison L,van der Loeff MS,Awasana AA,Gooding E,Bailey R,Mayaud P,West B

更新日期：2005-03-09 00:00:00

abstract：BACKGROUND:In current epidemiology of tuberculosis (TB), heterogeneity in infectiousness among TB patients is a challenge, which is not well studied. We aimed to quantify this heterogeneity and the presence of "super-spreading" events that can assist in designing optimal public health interventions. METHODS:TB epidemi...

journal_title：BMC infectious diseases

authors： Melsew YA,Gambhir M,Cheng AC,McBryde ES,Denholm JT,Tay EL,Trauer JM

更新日期：2019-03-12 00:00:00

abstract：BACKGROUND:HIV infection has been modifying both the epidemiology and outcome of parasitic infections. Hence, this study was undertaken to determine the prevalence of intestinal parasitic infection among people with and without HIV infection and its association with diarrhea and CD4 T-cell count. METHODS:A cross-secti...

journal_title：BMC infectious diseases

authors： Assefa S,Erko B,Medhin G,Assefa Z,Shimelis T

更新日期：2009-09-18 00:00:00

abstract：BACKGROUND:Self-reported antiretroviral therapy (ART) adherence measures that are associated with plasma viral load (VL) are valuable to clinicians and researchers, but are rarely examined among groups vulnerable to dropping out of care. One-seventh of all those living with HIV pass through incarceration annually and c...

journal_title：BMC infectious diseases

authors： Cunningham WE,Nance RM,Golin CE,Flynn P,Knight K,Beckwith CG,Kuo I,Spaulding A,Taxman FS,Altice F,Delaney JA,Crane HM,Springer SA

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:To assess the economic aspects of HBV (hepatitis B virus) transmission prevention for premarriage individuals in a country with cultural backgrounds like Iran and intermediate endemicity of HBV infection. METHODS:A cost-effectiveness analysis model was used from the health care system and society perspectiv...

journal_title：BMC infectious diseases

authors： Adibi P,Rezailashkajani M,Roshandel D,Behrouz N,Ansari S,Somi MH,Shahraz S,Zali MR

更新日期：2004-09-04 00:00:00

abstract：BACKGROUND:Salmonella enterica, serovar Typhi (S. Typhi), a causative agent of enteric fever (typhoid fever), predominately affects populations in developing regions with poor access to clean food and water. In addition, travelers to these regions are at risk of exposure. METHODS:We report the epidemiological characte...

journal_title：BMC infectious diseases

authors： Sorrell T,Selig DJ,Riddle MS,Porter CK

更新日期：2015-10-14 00:00:00

abstract：BACKGROUND:Alcohol use has a detrimental impact on the HIV epidemic, especially in sub-Saharan Africa. HIV counseling and testing (HCT) may provide a contact opportunity to intervene with hazardous alcohol use; however, little is known about how alcohol consumption changes following HCT. METHODS:We utilized data from ...

journal_title：BMC infectious diseases

authors： Hahn JA,Fatch R,Wanyenze RK,Baveewo S,Kamya MR,Bangsberg DR,Coates TJ

更新日期：2014-07-20 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) is a major global health problem and remains the leading cause of morbidity and mortality in developing countries. Routinely used TB diagnostic methods, in most endemic areas, are time-consuming, often less-sensitive, expensive and inaccessible to most patients. Therefore, there is an urgen...

journal_title：BMC infectious diseases

authors： Bentaleb EM,Abid M,El Messaoudi MD,Lakssir B,Ressami EM,Amzazi S,Sefrioui H,Ait Benhassou H

更新日期：2016-09-27 00:00:00