Abstract:
BACKGROUND:Acute reduction in hemoglobin levels is frequently seen during sepsis. Previous studies have focused on the management of anemia in patients with septic shock admitted to intensive care units (ICU's), including aggressive blood transfusion aiming to enhance tissue oxygenation. AIM:To study the changes in hemoglobin concentrations during the first week of sepsis in the setting of Internal Medicine (IM) units, and their correlation to survival. DESIGN:Observational prospective study. METHODS:We recorded hemoglobin values upon admission and throughout the first week of hospital stay in a consecutive cohort of septic patients admitted to IM units at a community hospital, the patients were enrolled into a prospective registry. Data on blood transfusions was also collected, we examined the correlation between hemoglobin concentrations during the first week of sepsis and survival, the effect of blood transfusion was also assessed. RESULTS:Eight hundred and fifteen patients (815) with sepsis were enrolled between February 2008 to January 2009. More than 20 % of them had hemoglobin levels less than 10g/dL on admission, a rate that was doubled during the first week of sepsis. Overall, 68 (8.3 %) received blood transfusions, 14 of them (20.6 %) due to bleeding. Typically, blood transfusion was given to older patients with a higher rate of malignancy and lower hemoglobin levels. While hemoglobin concentration on admission had strong correlation with in-hospital mortality (O.R-0.83 [95 % C.I. 0.74-0.92], blood transfusion was not found to be an independent predicting factor for mortality. CONCLUSION:Anemia is very common in sepsis. While hemoglobin level on admission exhibit independent correlation with survival, blood transfusion do not.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Muady GF,Bitterman H,Laor A,Vardi M,Urin V,Ghanem-Zoubi Ndoi
10.1186/s12879-016-1882-7subject
Has Abstractpub_date
2016-10-13 00:00:00pages
569issue
1issn
1471-2334pii
10.1186/s12879-016-1882-7journal_volume
16pub_type
杂志文章abstract:BACKGROUND:Dose-response assessment is one step in quantitative microbial risk assessment (QMRA). Four infectious microbes capable of causing respiratory diseases important to public health, and for which dose-response functions have not been available are: Bordetella pertussis (whooping cough), group A Streptococcus (...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-0832-0
更新日期:2015-02-24 00:00:00
abstract:BACKGROUND:Risk of pneumocystosis after discontinuation of primary or secondary prophylaxis among HIV-infected patients before CD4 counts increase to >==200 cells/microL (early discontinuation) after receiving highly active antiretroviral therapy (HAART) is rarely investigated. METHODS:Medical records of 660 HIV-infec...
journal_title:BMC infectious diseases
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1186/s12879-015-1144-0
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journal_title:BMC infectious diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12879-017-2263-6
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abstract:BACKGROUND:Syndromic surveillance is increasingly being evaluated for its potential for early warning of increased disease activity in the population. However, interpretation is hampered by the difficulty of attributing a causative pathogen. We described the temporal relationship between laboratory counts of influenza ...
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pub_type: 杂志文章
doi:10.1186/1471-2334-9-190
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pub_type: 杂志文章
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journal_title:BMC infectious diseases
pub_type: 杂志文章
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更新日期:2002-11-25 00:00:00
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更新日期:2018-06-08 00:00:00
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pub_type: 杂志文章
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更新日期:2017-03-20 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2015-03-15 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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