An economic analysis of premarriage prevention of hepatitis B transmission in Iran.

Abstract:

BACKGROUND:To assess the economic aspects of HBV (hepatitis B virus) transmission prevention for premarriage individuals in a country with cultural backgrounds like Iran and intermediate endemicity of HBV infection. METHODS:A cost-effectiveness analysis model was used from the health care system and society perspectives. The effectiveness was defined as the number of chronic HBV infections averted owing to one of the following strategies:1) HBsAg screening to find those would-be couples one of whom is HBsAg positive and putting seronegative subjects on a protection protocol comprising HBV vaccination, single dose HBIG and condom protection.2) HBsAg screening as above, in addition to performing HBcAb screening in the HBsAg negative spouses of the HBsAg positive persons and giving the protocol only to HBcAb negative ones.Sensitivity and threshold analyses were conducted. RESULTS:The cost of each chronic infection averted was 202$ and 197$ for the strategies 1 and 2, respectively. Sensitivity analysis showed that strategy 2 was always slightly cheaper than strategy 1. The discounted threshold value for the lifetime costs of chronic liver disease, above which the model was cost saving was 2818$ in strategy 1 and 2747$ in strategy 2. CONCLUSIONS:Though premarriage prevention of HBV transmission in the countries with cultural backgrounds similar to Iran seems cost saving, further studies determining precise costs of HBV infection in Iran can lead to a better analysis.

journal_name

BMC Infect Dis

journal_title

BMC infectious diseases

authors

Adibi P,Rezailashkajani M,Roshandel D,Behrouz N,Ansari S,Somi MH,Shahraz S,Zali MR

doi

10.1186/1471-2334-4-31

keywords:

subject

Has Abstract

pub_date

2004-09-04 00:00:00

pages

31

issn

1471-2334

pii

1471-2334-4-31

journal_volume

4

pub_type

杂志文章
  • Infection with high proportion of multidrug-resistant bacteria in conflict-related injuries is associated with poor outcomes and excess resource consumption: a cohort study of Syrian patients treated in Jordan.

    abstract:BACKGROUND:Armed conflicts are a major contributor to injury and death globally. Conflict-related injuries are associated with a high risk of wound infection, but it is unknown to what extent infection directly relates to sustainment of life and restoration of function. The aim of this study was to investigate the outc...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3149-y

    authors: Älgå A,Wong S,Shoaib M,Lundgren K,Giske CG,von Schreeb J,Malmstedt J

    更新日期:2018-05-22 00:00:00

  • Parasitic contamination of vegetables marketed in Arba Minch town, southern Ethiopia.

    abstract:BACKGROUND:Consumption of unwashed, raw or unhygienically prepared fruits and vegetables act as potential source for the spread of various parasitic diseases. Moreover, the level of contamination and species of contaminant parasites vary from place to place because of variations in environmental and human factors. Ther...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4020-5

    authors: Alemu G,Mama M,Misker D,Haftu D

    更新日期:2019-05-14 00:00:00

  • Oxidative stress markers in saliva and periodontal disease status: modulation during pregnancy and postpartum.

    abstract:BACKGROUND:Periodontal diseases may affect local and systemic inflammation, and reactive oxygen species (ROS) levels. This systemic health burden could compromise the outcome of pregnancy in expectant mothers. The aim of the present study was to evaluate oxidative stress markers, including glutathione peroxidase (GPx),...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-1003-z

    authors: Gümüş P,Emingil G,Öztürk VÖ,Belibasakis GN,Bostanci N

    更新日期:2015-07-08 00:00:00

  • Serum markers in interstitial pneumonia with and without Pneumocystis jirovecii colonization: a prospective study.

    abstract:BACKGROUND:In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation. Pneumocystis pneumonia causes interstitial changes, so making a diagnosis of PCP in patients who have interstitial pneumonia (IP) with...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-9-47

    authors: Shimizu Y,Sunaga N,Dobashi K,Fueki M,Fueki N,Makino S,Mori M

    更新日期:2009-04-22 00:00:00

  • Prevalence, intensity and factors associated with soil-transmitted helminths infections among preschool-age children in Hoima district, rural western Uganda.

    abstract:BACKGROUND:Over 80% of morbidity due to soil-transmitted helminthiasis (STH) occurs in low-income countries. Children under 5 account for 20-30% of the burden in endemic areas. This study assessed the prevalence, intensity and factors associated with STH infections among preschool-age children (PSAC) in Hoima district,...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3289-0

    authors: Ojja S,Kisaka S,Ediau M,Tuhebwe D,Kisakye AN,Halage AA,Mugambe RK,Mutyoba JN

    更新日期:2018-08-17 00:00:00

  • Detection of viable but non-culturable Pseudomonas aeruginosa in cystic fibrosis by qPCR: a validation study.

    abstract:BACKGROUND:Routine culture-based diagnosis of Pseudomonas aeruginosa lung infection in Cystic Fibrosis (CF) patients can be hampered by the phenotypic variability of the microorganism, including its transition to a Viable But Non-Culturable (VBNC) state. The aim of this study was to validate an ecfX-targeting qPCR prot...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3612-9

    authors: Mangiaterra G,Amiri M,Di Cesare A,Pasquaroli S,Manso E,Cirilli N,Citterio B,Vignaroli C,Biavasco F

    更新日期:2018-12-27 00:00:00

  • Interleukin-28B gene non-TT allele strongly predicts treatment failure for genotype 1 infected chronic hepatitis C patients with advanced fibrosis: a case control study.

    abstract:BACKGROUND:The role of single nucleotide polymorphisms (SNPs) of interleukin (IL)-28B in predicting therapeutic response of pegylated interferon (peg-IFN) plus ribavirin (PR) for genotype 1 infected chronic hepatitis C patients with advanced fibrosis (AF) is limited. The aim of this study is to assess its role in predi...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-0888-x

    authors: Hu CC,Lin CL,Chang LC,Chien CH,Chen LW,Liu CJ,Chien RN

    更新日期:2015-03-26 00:00:00

  • A model-based economic analysis of pre-pandemic influenza vaccination cost-effectiveness.

    abstract:BACKGROUND:A vaccine matched to a newly emerged pandemic influenza virus would require a production time of at least 6 months with current proven techniques, and so could only be used reactively after the peak of the pandemic. A pre-pandemic vaccine, although probably having lower efficacy, could be produced and used p...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-14-266

    authors: Halder N,Kelso JK,Milne GJ

    更新日期:2014-05-16 00:00:00

  • Outbreak of Middle East respiratory syndrome coronavirus in Saudi Arabia: a retrospective study.

    abstract:BACKGROUND:The Middle East respiratory syndrome (MERS) is proposed to be a zoonotic disease. Dromedary camels have been implicated due to reports that some confirmed cases were exposed to camels. Risk factors for MERS coronavirus (MERS-CoV) infections in humans are incompletely understood. This study aimed to describe ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-2137-3

    authors: Aleanizy FS,Mohmed N,Alqahtani FY,El Hadi Mohamed RA

    更新日期:2017-01-05 00:00:00

  • A case report of HIV-1 superinfection in an HIV controller leading to loss of viremia control: a retrospective of 10 years of follow-up.

    abstract:BACKGROUND:HIV controllers (HICs) are a rare group of HIV-1-infected individuals able to naturally control viral replication. Several studies have identified the occurrence of HIV dual infections in seropositive individuals leading to disease progression. In HICs, however, dual infections with divergent outcomes in pat...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4229-3

    authors: Caetano DG,Côrtes FH,Bello G,de Azevedo SSD,Hoagland B,Villela LM,Grinsztejn B,Veloso VG,Guimarães ML,Morgado MG

    更新日期:2019-07-05 00:00:00

  • The influence of carbapenem resistance on mortality in solid organ transplant recipients with Acinetobacter baumannii infection.

    abstract:BACKGROUND:Infection with carbapenem-resistant Acinetobacter baumannii has been associated with high morbidity and mortality in solid organ transplant recipients. The main objective of this study was to assess the influence of carbapenem resistance and other potential risk factors on the outcome of A. baumannii infecti...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-12-351

    authors: de Gouvêa EF,Martins IS,Halpern M,Ferreira AL,Basto ST,Gonçalves RT,Moreira BM,Santoro-Lopes G

    更新日期:2012-12-13 00:00:00

  • Correction to: Seasonal dynamics of influenza in Brazil: the latitude effect.

    abstract::Following publication. ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,已发布勘误

    doi:10.1186/s12879-019-3739-3

    authors: Almeida A,Codeço C,Luz PM

    更新日期:2019-03-04 00:00:00

  • Characterization of methicillin-susceptible and -resistant staphylococci in the clinical setting: a multicentre study in Nigeria.

    abstract:BACKGROUND:The staphylococci are implicated in a variety of human infections; however, many clinical microbiology laboratories in Nigeria do not identify staphylococci (in particular coagulase negative staphylococci - CNS) to the species level. Moreover, data from multi-centre assessment on antibiotic resistance and ep...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-12-286

    authors: Shittu A,Oyedara O,Abegunrin F,Okon K,Raji A,Taiwo S,Ogunsola F,Onyedibe K,Elisha G

    更新日期:2012-11-02 00:00:00

  • Characteristics of invasive Acinetobacter species isolates recovered in a pediatric academic center.

    abstract:BACKGROUND:Acinetobacter species are associated with increasing mortality due to emerging drug-resistance. Pediatric Acinetobacter infections are largely undefined in developed countries and clinical laboratory identification methods do not reliably differentiate between members of the Acinetobacter calcoaceticus-bauma...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1678-9

    authors: Jain AL,Harding CM,Assani K,Shrestha CL,Haga M,Leber A,Munson RS Jr,Kopp BT

    更新日期:2016-07-22 00:00:00

  • Identifying risks for severity of neurological symptoms in Hungarian West Nile virus patients.

    abstract:BACKGROUND:West Nile virus (WNV) infections have become increasingly prevalent in certain European countries, including Hungary. Although most human infections do not cause severe symptoms, in approximately 1% of cases WNV infections can lead to severe WNV neuroinvasive disease (WNND) and death. The goal of our study w...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05760-7

    authors: Koch M,Pozsgai É,Soós V,Nagy A,Girán J,Nyisztor N,Martyin T,Müller Z,Fehér M,Hajdú E,Varga C

    更新日期:2021-01-13 00:00:00

  • Utility of total lymphocyte count as a surrogate marker for CD4 counts in HIV-1 infected children in Kenya.

    abstract:BACKGROUND:In resource-limited settings, such as Kenya, access to CD4 testing is limited. Therefore, evaluation of less expensive laboratory diagnostics is urgently needed to diagnose immuno-suppression in children. OBJECTIVES:To evaluate utility of total lymphocyte count (TLC) as surrogate marker for CD4 count in HIV...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-11-259

    authors: Githinji N,Maleche-Obimbo E,Nderitu M,Wamalwa DC,Mbori-Ngacha D

    更新日期:2011-09-30 00:00:00

  • Post-traumatic osteomyelitis in Middle East war-wounded civilians: resistance to first-line antibiotics in selected bacteria over the decade 2006-2016.

    abstract:BACKGROUND:War-wounded civilians in Middle East countries are at risk of post-traumatic osteomyelitis (PTO). We aimed to describe and compare the bacterial etiology and proportion of first-line antibiotics resistant bacteria (FLAR) among PTO cases in civilians from Syria, Iraq and Yemen admitted to the reconstructive s...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-3741-9

    authors: Fily F,Ronat JB,Malou N,Kanapathipillai R,Seguin C,Hussein N,Fakhri RM,Langendorf C

    更新日期:2019-01-31 00:00:00

  • Solidarity, vulnerability and mistrust: how context, information and government affect the lives of women in times of Zika.

    abstract:BACKGROUND:The public health response to Zika outbreak has mostly focused on epidemiological surveillance, vector control, and individual level preventative measures. This qualitative study employs a social-ecological framework to examine how macro (historical, legislative, political, socio-economic factors), meso (sou...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-04987-8

    authors: Linde-Arias AR,Roura M,Siqueira E

    更新日期:2020-04-03 00:00:00

  • Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study of aseptic meningitis.

    abstract:BACKGROUND:The seasonality, clinical and radiographic features and outcome of aseptic meningitis have been described for regional outbreaks but data from a wider geographic area is necessary to delineate the epidemiology of this condition. METHODS:A retrospective chart review was completed of children presenting with ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-6-68

    authors: Lee BE,Chawla R,Langley JM,Forgie SE,Al-Hosni M,Baerg K,Husain E,Strong J,Robinson JL,Allen U,Law BJ,Dobson S,Davies HD

    更新日期:2006-04-10 00:00:00

  • Increase of serotypes 15A and 23B in IPD in Germany in the PCV13 vaccination era.

    abstract:BACKGROUND:This study presents an analysis of 1,491 serogroup 23 and 762 serogroup 15 isolates from invasive pneumococcal disease (IPD) in children and adults before and after the general recommendation for childhood pneumococcal conjugate vaccination in Germany in July 2006. Vaccination formulations used were PCV7 (fr...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-0941-9

    authors: van der Linden M,Perniciaro S,Imöhl M

    更新日期:2015-05-05 00:00:00

  • Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies.

    abstract::Detection of the Mycobacterium tuberculosis cell wall antigen lipoarabinomannan (LAM) in urine permits diagnoses of tuberculosis (TB) to be made in HIV-infected patients with advanced immunodeficiency. This can be achieved at the point-of-care within just 30 minutes using the Determine TB-LAM, which is a commercially ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-407

    authors: Lawn SD,Dheda K,Kerkhoff AD,Peter JG,Dorman S,Boehme CC,Nicol MP

    更新日期:2013-09-03 00:00:00

  • Incidence, risk factors, and outcomes of Fusobacterium species bacteremia.

    abstract:BACKGROUND:Fusobacterium species (spp.) bacteremia is uncommon and has been associated with a variety of clinical presentations. We conducted a retrospective, population based study to determine the relative proportion of species in this genus causing bacteremia and the risk factors for infection and adverse clinical o...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-264

    authors: Afra K,Laupland K,Leal J,Lloyd T,Gregson D

    更新日期:2013-06-05 00:00:00

  • Efficacy of ceftazidime-avibactam in the treatment of infections due to Carbapenem-resistant Enterobacteriaceae.

    abstract:BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) represent an important global threat. The aim of this study is to describe the clinical course and outcomes of patients with CRE infections treated with ceftazidime-avibactam (CAZ-AVI) compared to patients treated with other agents. METHODS:A retrospective cohor...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4409-1

    authors: Alraddadi BM,Saeedi M,Qutub M,Alshukairi A,Hassanien A,Wali G

    更新日期:2019-09-04 00:00:00

  • Correlation between polymorphisms in toll-like receptor genes and the activity of hepatitis B virus among treatment-naïve patients: a case-control study in a Han Chinese population.

    abstract:BACKGROUND:Because of the high prevalence and absence of cure for infection, chronic hepatitis B virus (HBV) infection has been acknowledged as a pressing public health issue. Toll-like receptors (TLRs) activate the human innate immune system and the polymorphisms in TLRs may alter their function. The present study aim...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-2943-x

    authors: Lin Y,Gao ZX,Shen X,Chen MJ,Li YT,Li SL,Lin HL,Zhao QF,Liu F,Niu JJ

    更新日期:2018-01-10 00:00:00

  • Prevalence of systemic immunoreactivity to Aggregatibacter actinomycetemcomitans leukotoxin in relation to the incidence of myocardial infarction.

    abstract:BACKGROUND:Chronic infections and associated inflammatory markers are suggested risk factors for cardiovascular disease (CVD). The proinflammatory cytokine, interleukin (IL)-1β, is suggested to play a role in the regulation of local inflammatory responses in both CVD and periodontitis. The leukotoxin from the periodont...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-11-55

    authors: Johansson A,Eriksson M,Ahrén AM,Boman K,Jansson JH,Hallmans G,Johansson I

    更新日期:2011-03-01 00:00:00

  • BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy.

    abstract:BACKGROUND:Adjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce. Here, we investigated BKPyV-specific T cell immunity in KT recipients diagnosed with BKPyVAN. METHO...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4615-x

    authors: Bruminhent J,Srisala S,Klinmalai C,Pinsai S,Watcharananan SP,Kantachuvesiri S,Hongeng S,Apiwattanakul N

    更新日期:2019-11-19 00:00:00

  • Neonatal septicemia caused by a rare pathogen: Raoultella planticola - a report of four cases.

    abstract:BACKGROUND:Raoultella planticola(R.planticola) is a very rare opportunistic pathogen and sometimes even associated with fatal infection in pediatric cases. Recently,the emergence of carbapenem resistance strains are constantly being reported and a growing source of concern for pediatricians. CASE PRESENTATION:We repor...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05409-5

    authors: Chen X,Guo S,Liu D,Zhong M

    更新日期:2020-09-16 00:00:00

  • Whole-genome enrichment and sequencing of Chlamydia trachomatis directly from clinical samples.

    abstract:BACKGROUND:Chlamydia trachomatis is a pathogen of worldwide importance, causing more than 100 million cases of sexually transmitted infections annually. Whole-genome sequencing is a powerful high resolution tool that can be used to generate accurate data on bacterial population structure, phylogeography and mutations a...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-014-0591-3

    authors: Christiansen MT,Brown AC,Kundu S,Tutill HJ,Williams R,Brown JR,Holdstock J,Holland MJ,Stevenson S,Dave J,Tong CY,Einer-Jensen K,Depledge DP,Breuer J

    更新日期:2014-11-12 00:00:00

  • Effectiveness of the polysaccharide pneumococcal vaccine among HIV-infected persons in Brazil: a case control study.

    abstract:BACKGROUND:Polysaccharide pneumococcal vaccine is recommended for use in HIV-infected adults in Brazil but there is uncertainty about its effectiveness in this patient population. The main objective of this study was to assess the effectiveness of the 23-valent polysaccharide pneumococcal vaccine against invasive pneum...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2334-7-119

    authors: Veras MA,Enanoria WT,Castilho EA,Reingold AL

    更新日期:2007-10-23 00:00:00

  • Feasibility and acceptability of home-based HIV testing among refugees: a pilot study in Nakivale refugee settlement in southwestern Uganda.

    abstract:BACKGROUND:Refugees in sub-Saharan Africa face both the risk of HIV infection and barriers to HIV testing. We conducted a pilot study to determine the feasibility and acceptability of home-based HIV testing in Nakivale Refugee Settlement in Uganda and to compare home-based and clinic-based testing participants in Nakiv...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3238-y

    authors: O'Laughlin KN,He W,Greenwald KE,Kasozi J,Chang Y,Mulogo E,Faustin ZM,Njogu P,Walensky RP,Bassett IV

    更新日期:2018-07-16 00:00:00