The burden of varicella from a parent's perspective and its societal impact in The Netherlands: an Internet survey.

Abstract:

BACKGROUND:Varicella is a common childhood disease. Only 5% of first varicella-zoster-virus infections occur asymptomatically. Most data on the burden of varicella stem from health service databases. This study aims to provide insight in the burden of varicella from a parent's perspective including cases outside the healthcare system. METHODS:An internet questionnaire was developed for parents in the Netherlands to report health care resource use and productivity losses during the varicella episode in their child younger than 6 years. 11,367 invitations were sent out to members with children of an internet panel of a market research agency. 4,168 (37%) parents started the questionnaire (response rate), of which 360 (9%) stopped before completion and 1,838 (44%) were out of the target group. In total 1,970 parents completed the questionnaire. The questionnaire provided a symptom list ranging from common symptoms, such as skin vesicles, itching to fits or convulsions. A posteriori, in the analyses, the symptoms 'skin infections', 'fits/convulsions', 'unconsciousness', and 'balance and movement disorders' were labelled as complications. There was no restriction to time since the varicella episode for inclusion in the analyses. RESULTS:The 1,970 respondents had in total 2,899 children aged younger than six years, of which 2,564 (88%) children had had varicella. In 62% of the episodes the parent did not seek medical help. In 18% of all episodes symptoms labelled as complications were reported; in 11% of all episodes parents visited a medical doctor (MD) for a complication. Reporting of complications did not differ (X2 ; p = 0.964) between children with a recent (≤ 12 months ago) or a more distant (> 12 months) history of varicella. Prescription drugs were used in 12% of the children with varicella; OTC drugs in 72%. Parents reported work loss in 17% of the varicella-episodes (23% when MD visit; 14% when no MD-visit) for on average 14 hours, which equals to 2.5 hours of work loss for any given varicella-episode. CONCLUSIONS:This study shows the full spectrum of varicella-episodes and associated healthcare use, including the large proportion of cases not seeking medical care and the societal impact associated with those cases.

journal_name

BMC Infect Dis

journal_title

BMC infectious diseases

authors

Wolleswinkel-van den Bosch JH,Speets AM,Rümke HC,Gumbs PD,Fortanier SC

doi

10.1186/1471-2334-11-320

subject

Has Abstract

pub_date

2011-11-17 00:00:00

pages

320

issn

1471-2334

pii

1471-2334-11-320

journal_volume

11

pub_type

杂志文章
  • Tuberculosis infection risk, preventive therapy care cascade and incidence of tuberculosis disease in healthcare workers at Maputo Central Hospital.

    abstract:BACKGROUND:Mozambican healthcare workers have high rates of latent and active tuberculosis, but occupational screening for tuberculosis is not routine in this setting. Furthermore, the specificity of tuberculin skin testing in this population compared with interferon gamma release assay testing has not been established...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-3966-7

    authors: Graves SK,Augusto O,Viegas SO,Lederer P,David C,Lee K,Hassane A,Cossa A,Amade S,Peleve S,Zindoga P,Massawo L,Torriani FJ,Nunes EA

    更新日期:2019-04-25 00:00:00

  • Immunological and virological characterization of HIV-1 viremia controllers in the North Region of Brazil.

    abstract:BACKGROUND:A rare phenotype of clinical non-progressors to AIDS is not well understood and the new protocol for universal treatment, may block the understanding of viral control thus it is crucial to define this controversial group. METHODS:A cohort of 30 persons followed a criteria for viremia control groups 1 (VC1; ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2491-9

    authors: Gomes STM,Gomes ÉR,Dos Santos MB,Lima SS,Queiroz MAF,Machado LFA,Cayres-Vallinoto IMV,Vallinoto ACR,de O Guimarães Ishak M,Ishak R

    更新日期:2017-06-01 00:00:00

  • Clonal replacement of epidemic KPC-producing Klebsiella pneumoniae in a hospital in China.

    abstract:BACKGROUND:Klebsiella pneumoniae is a frequent nosocomial pathogen causing difficult-to-treat infections worldwide. The prevalence of Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-KP) is increasing in China. The aim of this study was to investigate the molecular epidemiology of KPC-KP i...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2467-9

    authors: Liang Y,Yin X,Zeng L,Chen S

    更新日期:2017-05-23 00:00:00

  • The efficacy of vacuum-ultraviolet light disinfection of some common environmental pathogens.

    abstract:BACKGROUND:This study is to elucidate the disinfection effect of ozone producing low-pressure Hg vapor lamps against human pathogens. Ozone producing low-pressure Hg vapor lamps emit mainly 254 nm ultraviolet light C (UVC) with about 10% power of Vacuum-ultraviolet (VUV) light at 185 nm. The combination of UVC and VUV ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-4847-9

    authors: Szeto W,Yam WC,Huang H,Leung DYC

    更新日期:2020-02-11 00:00:00

  • Lymphocyte transformation assay for C neoformans antigen is not reliable for detecting cellular impairment in patients with neurocryptococcosis.

    abstract:BACKGROUND:Cryptococcus neoformans causes meningitis and disseminated infection in healthy individuals, but more commonly in hosts with defective immune responses. Cell-mediated immunity is an important component of the immune response to a great variety of infections, including yeast infections. We aimed to evaluate a...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-12-278

    authors: Rocha KC,Pinhal C,Cavalcanti S,Vidal MS,Toscano M,Moraes-Vasconcelos D,Duarte AJ,Fonseca FL,de Abreu LC,Valenti VE,Grumach AS

    更新日期:2012-10-30 00:00:00

  • Fasting plasma glucose is an independent predictor for severity of H1N1 pneumonia.

    abstract:BACKGROUND:The pandemic influenza A (H1N1) virus emerged during 2009 and has spread worldwide. This virus can cause injuries to the lungs, liver, and heart. However, data regarding whether this influenza virus can affect pancreatic islets are limited. We investigated the effects of influenza A (H1N1) pneumonia on fasti...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-11-104

    authors: Wang W,Chen H,Li Q,Qiu B,Wang J,Sun X,Xiang Y,Zhang J

    更新日期:2011-04-21 00:00:00

  • Intestinal parasitic infections in relation to HIV/AIDS status, diarrhea and CD4 T-cell count.

    abstract:BACKGROUND:HIV infection has been modifying both the epidemiology and outcome of parasitic infections. Hence, this study was undertaken to determine the prevalence of intestinal parasitic infection among people with and without HIV infection and its association with diarrhea and CD4 T-cell count. METHODS:A cross-secti...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-9-155

    authors: Assefa S,Erko B,Medhin G,Assefa Z,Shimelis T

    更新日期:2009-09-18 00:00:00

  • Clinical characteristics of acute hepatitis A outbreak in Taiwan, 2015-2016: observations from a tertiary medical center.

    abstract:BACKGROUND:Acute hepatitis A is a fecal-oral transmitted disease related to inadequate sanitary conditions. In addition to its traditional classification, several outbreaks in the men who have sex with men (MSM) population have resulted in acute hepatitis A being recognized as a sexually transmitted disease. However, f...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2555-x

    authors: Chen NY,Liu ZH,Shie SS,Chen TH,Wu TS

    更新日期:2017-06-20 00:00:00

  • Carbapenem-resistant Klebsiella pneumoniae in high-risk haematological patients: factors favouring spread, risk factors and outcome of carbapenem-resistant Klebsiella pneumoniae bacteremias.

    abstract:BACKGROUND:Carbapenem-resistant Klebsiella pneumoniae (CRKP) spread and infections in patients with haematological malignancies are a serious concern especially in endemic areas. Treatment failures and delay in appropriate therapy for CRKP infections are frequent and the mortality rate associated with CRKP bacteremia i...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2297-9

    authors: Micozzi A,Gentile G,Minotti C,Cartoni C,Capria S,Ballarò D,Santilli S,Pacetti E,Grammatico S,Bucaneve G,Foà R

    更新日期:2017-03-10 00:00:00

  • Detrimental role for CCAAT/enhancer binding protein δ in blood-borne brain infection.

    abstract:BACKGROUND:The most frequent pathogen that causes bacterial meningitis is the Gram-positive bacterium Streptococcus (S.) pneumoniae. CCAAT/enhancer binding protein δ is a transcription factor that has recently been hypothesized to play a detrimental role in outcome of meningitis caused by S. pneumoniae. Here, we studie...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1963-7

    authors: Duitman J,Valls Serón M,Engelen-Lee J,Brouwer MC,Spek CA,van de Beek D

    更新日期:2016-11-11 00:00:00

  • Personality disorders do not affect treatment outcomes for chronic HCV infection in Spanish prisoners: the Perseo study.

    abstract:BACKGROUND:The link between infection with hepatitis C virus (HCV) and personality disorders (PD) has not been investigated in detail. The aim of this study was to compare the effectiveness of HCV treatment in prisoners with and without PD. METHODS:We performed a prospective multicentre study in inmates from 25 Spanis...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12879-015-1102-x

    authors: Marco A,Antón JJ,Trujols J,Saíz de la Hoya P,de Juan J,Faraco I,Caylà JA,Perseo Group.

    更新日期:2015-08-19 00:00:00

  • Trends in baseline CD4 cell counts and risk factors for late antiretroviral therapy initiation among HIV-positive patients in Shanghai, a retrospective cross-sectional study.

    abstract:BACKGROUNDS:There are few studies focus on the factors underlying the late initiation of ART in China. We analyzed the trends in the median CD4 cell counts among different patient groups over time and the risk factors for the late initiation of ART in Shanghai, China. METHODS:A retrospective cross-sectional survey was...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2398-5

    authors: Sun J,Liu L,Shen J,Chen P,Lu H

    更新日期:2017-04-19 00:00:00

  • Molecular epidemiology of giardiasis among Orang Asli in Malaysia: application of the triosephosphate isomerase gene.

    abstract:BACKGROUND:Giardia duodenalis is a flagellate parasite which has been considered the most common protozoa infecting human worldwide. Molecular characterization of G. duodenalis isolates have revealed the existence of eight groups (Assemblage A to H) which differ in their host distribution. Assemblages A and B are found...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-14-78

    authors: Anuar TS,Azreen SN,Salleh FM,Moktar N

    更新日期:2014-02-12 00:00:00

  • Male circumcision and prevalence of genital human papillomavirus infection in men: a multinational study.

    abstract:BACKGROUND:Accumulated evidence from epidemiological studies and more recently from randomized controlled trials suggests that male circumcision (MC) may substantially protect against genital HPV infection in men. The purpose of this study was to assess the association between MC and genital HPV infection in men in a l...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-18

    authors: Albero G,Villa LL,Lazcano-Ponce E,Fulp W,Papenfuss MR,Nyitray AG,Lu B,Castellsagué X,Abrahamsen M,Smith D,Bosch FX,Salmerón J,Quiterio M,Giuliano AR

    更新日期:2013-01-17 00:00:00

  • Genomic characterization of MDR/XDR-TB in Kazakhstan by a combination of high-throughput methods predominantly shows the ongoing transmission of L2/Beijing 94-32 central Asian/Russian clusters.

    abstract:BACKGROUND:Kazakhstan remains a high-burden TB prevalence country with a concomitent high-burden of multi-drug resistant tuberculosis. For this reason, we performed an in depth genetic diversity and population structure characterization of Mycobacterium tuberculosis complex (MTC) genetic diversity in Kazakhstan with bo...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4201-2

    authors: Klotoe BJ,Kacimi S,Costa-Conceicão E,Gomes HM,Barcellos RB,Panaiotov S,Haj Slimene D,Sikhayeva N,Sengstake S,Schuitema AR,Akhalaia M,Alenova A,Zholdybayeva E,Tarlykov P,Anthony R,Refrégier G,Sola C

    更新日期:2019-06-24 00:00:00

  • The association of HPV-16 seropositivity and natural immunity to reinfection: insights from compartmental models.

    abstract:BACKGROUND:Seroreactivity, processes of seroconversion and seroreversion, in the context of HPV infection has been investigated in numerous studies. However, the data resulting from these studies are usually not accounted for in mathematical transmission models of various HPV types due to gaps in our understanding of t...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-83

    authors: Korostil IA,Garland SM,Law MG,Regan DG

    更新日期:2013-02-13 00:00:00

  • Promoting routine syphilis screening among men who have sex with men in China: study protocol for a randomised controlled trial of syphilis self-testing and lottery incentive.

    abstract:BACKGROUND:Men who have sex with men (MSM) bear a high burden of syphilis infection. Expanding syphilis testing to improve timely diagnosis and treatment is critical to improve syphilis control. However, syphilis testing rates remain low among MSM, particularly in low- and middle-income countries. We describe the proto...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12879-020-05188-z

    authors: Cheng W,Wang C,Tang W,Ong JJ,Fu H,Marks M,Smith MK,Li C,Nie J,Zhao P,Zheng H,Yang B,Tucker JD

    更新日期:2020-06-29 00:00:00

  • Factors related to outcome of bloodstream infections due to Candida parapsilosis complex.

    abstract:BACKGROUND:Although Candida albicans is the most common cause of fungal blood stream infections (BSIs), infections due to Candida species other than C. albicans are rising. Candida parapsilosis complex has emerged as an important fungal pathogen and became one of the main causes of fungemia in specific geographical are...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1704-y

    authors: Barchiesi F,Orsetti E,Osimani P,Catassi C,Santelli F,Manso E

    更新日期:2016-08-09 00:00:00

  • Chronic Candida infection, bronchiectasis, immunoglobulin abnormalities, and stunting: a case report of a natural mutation of STAT1 (c.986C>G) in an adolescent male.

    abstract:BACKGROUND:Chronic mucocutaneous candidiasis (CMC) is the most common clinical symptom of singer transducer and signal transducer and activator of transcription 1 (STAT1) gain-of-function (GOF) mutations. Bronchiectasis is a chronic lung disease that is characterized by permanent bronchiectasis, causing cough, expector...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05734-9

    authors: Yu Y,Xu F,Shen H,Wu J

    更新日期:2021-01-07 00:00:00

  • Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal.

    abstract:BACKGROUND:Acute inflammatory reactions are a frequently occurring, tissue destructing phenomenon in infectious- as well as autoimmune diseases, providing clinical challenges for early diagnosis. In leprosy, an infectious disease initiated by Mycobacterium leprae (M. leprae), these reactions represent the major cause o...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12879-015-1128-0

    authors: Khadge S,Banu S,Bobosha K,van der Ploeg-van Schip JJ,Goulart IM,Thapa P,Kunwar CB,van Meijgaarden KE,van den Eeden SJ,Wilson L,Kabir S,Dey H,Goulart LR,Lobato J,Carvalho W,Bekele Y,Franken KL,Aseffa A,Spencer JS,Osk

    更新日期:2015-10-28 00:00:00

  • A cluster randomized trial for the implementation of an antibiotic checklist based on validated quality indicators: the AB-checklist.

    abstract:BACKGROUND:Recently we developed and validated generic quality indicators that define 'appropriate antibiotic use' in hospitalized adults treated for a (suspected) bacterial infection. Previous studies have shown that with appropriate antibiotic use a reduction of 13% of length of hospital stay can be achieved. Our mai...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12879-015-0867-2

    authors: van Daalen FV,Prins JM,Opmeer BC,Boermeester MA,Visser CE,van Hest RM,Hulscher ME,Geerlings SE

    更新日期:2015-03-19 00:00:00

  • The preliminary comparative results between Covid-19 and non-Covid-19 patients in Western China.

    abstract:BACKGROUND:This study aims to investigate the comparative clinical characteristics of Covid-19 and non-Covid-19 patients. METHODS:Fifteen Covid-19 and 93 non-Covid-19 patients were included in RNA testing. All epidemiological and clinical data were collected and analyzed, and then comparative results were carried out....

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05680-6

    authors: Li Y,Li H,Han J,Yang L

    更新日期:2020-12-09 00:00:00

  • Effectiveness of Progressive Resistive Exercise (PRE) in the context of HIV: systematic review and meta-analysis using the Cochrane Collaboration protocol.

    abstract:BACKGROUND:HIV is increasingly considered a chronic illness. More individuals are living longer and aging with the health-related consequences associated with HIV and multi-morbidity. Exercise is a self-management approach that can promote health for people aging with HIV. We examined the safety and effectiveness of pr...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12879-017-2342-8

    authors: O'Brien KK,Tynan AM,Nixon SA,Glazier RH

    更新日期:2017-04-12 00:00:00

  • Detection of hydrogen peroxide-producing Lactobacillus species in the vagina: a comparison of culture and quantitative PCR among HIV-1 seropositive women.

    abstract:BACKGROUND:The presence of hydrogen peroxide (H(2)O(2)) producing Lactobacillus in the vagina may play a role in controlling genital HIV-1 shedding. Sensitive molecular methods improve our ability to characterize the vaginal microbiota; however, they cannot characterize phenotype. We assessed the concordance of H(2)O(2...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-12-188

    authors: Balkus JE,Mitchell C,Agnew K,Liu C,Fiedler T,Cohn SE,Luque A,Coombs R,Fredricks DN,Hitti J

    更新日期:2012-08-13 00:00:00

  • Estimation of the burden of varicella in Europe before the introduction of universal childhood immunization.

    abstract:BACKGROUND:Varicella is generally considered a mild disease. Disease burden is not well known and country-level estimation is challenging. As varicella disease is not notifiable, notification criteria and rates vary between countries. In general, existing surveillance systems do not capture cases that do not seek medic...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12879-017-2445-2

    authors: Riera-Montes M,Bollaerts K,Heininger U,Hens N,Gabutti G,Gil A,Nozad B,Mirinaviciute G,Flem E,Souverain A,Verstraeten T,Hartwig S

    更新日期:2017-05-18 00:00:00

  • Hemoglobin levels and blood transfusion in patients with sepsis in Internal Medicine Departments.

    abstract:BACKGROUND:Acute reduction in hemoglobin levels is frequently seen during sepsis. Previous studies have focused on the management of anemia in patients with septic shock admitted to intensive care units (ICU's), including aggressive blood transfusion aiming to enhance tissue oxygenation. AIM:To study the changes in he...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1882-7

    authors: Muady GF,Bitterman H,Laor A,Vardi M,Urin V,Ghanem-Zoubi N

    更新日期:2016-10-13 00:00:00

  • Clinical and microbiological effect of pulsed xenon ultraviolet disinfection to reduce multidrug-resistant organisms in the intensive care unit in a Japanese hospital: a before-after study.

    abstract:BACKGROUND:No-touch environmental disinfection using ultraviolet devices has been highlighted in the past several years to control the transmission of multidrug-resistant organisms (MDROs). However, its effectiveness in non-US healthcare settings is yet to be examined. This study aimed to evaluate the effectiveness of ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-4805-6

    authors: Morikane K,Suzuki S,Yoshioka J,Yakuwa J,Nakane M,Nemoto K

    更新日期:2020-01-29 00:00:00

  • Prevalence of HPV high and low risk types in cervical samples from the Italian general population: a population based study.

    abstract:BACKGROUND:This multicenter study describes the type-specific prevalence of HPV infection in the general population from central and southern Italy, comparing the data with previously published Italian studies. METHODS:Women aged from 25 to 65 who attended cervical cancer screening in five different Italian regions we...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2334-10-214

    authors: Giorgi Rossi P,Bisanzi S,Paganini I,Di Iasi A,Angeloni C,Scalisi A,Macis R,Pini MT,Chini F,Carozzi FM,HPV Prevalence Italian Working Group.

    更新日期:2010-07-20 00:00:00

  • Significance of soluble triggering receptor expressed on myeloid cells-1 elevation in patients admitted to the intensive care unit with sepsis.

    abstract:BACKGROUND:Among septic patients admitted to the intensive care unit (ICU), early recognition of those with the highest risk of death is of paramount importance. Since clinical judgment is sometimes uncertain biomarkers could provide additional information likely to guide critical illness management. We evaluated the p...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1893-4

    authors: Charles PE,Noel R,Massin F,Guy J,Bollaert PE,Quenot JP,Gibot S

    更新日期:2016-10-12 00:00:00

  • TST positivity in household contacts of tuberculosis patients: a case-contact study in Malawi.

    abstract:BACKGROUND:Screening household contacts of active tuberculosis (TB) patients is recommended for TB control. Due to resource constraints this rarely occurs in lower income countries. Demographic and clinical features of index cases may influence the likelihood of onwards TB transmission. It has also been proposed that a...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2348-2

    authors: Hector J,Anderson ST,Banda G,Kamdolozi M,Jefferys LF,Shani D,Garton NJ,Mwale A,Jobe A,Davies GR,Sloan DJ

    更新日期:2017-04-11 00:00:00