Abstract:
BACKGROUND:HIV is increasingly considered a chronic illness. More individuals are living longer and aging with the health-related consequences associated with HIV and multi-morbidity. Exercise is a self-management approach that can promote health for people aging with HIV. We examined the safety and effectiveness of progressive resistive exercise (PRE) interventions on immunological, virological, cardiorespiratory, strength, weight, body composition, and psychological outcomes in adults living with HIV. METHODS:We conducted a systematic review using the Cochrane Collaboration protocol. Searching databases up to April 2013, we included randomized controlled trials that compared PRE with no exercise or another intervention performed at least three times per week for at least four weeks with adults living with HIV. Two reviewers independently determined study eligibility. We extracted data from included studies and assessed risk of bias using the Cochrane Collaboration risk of bias tool. Meta-analyses were conducted using random effects models with Review Manager (RevMan) computer software. RESULTS:Twenty studies met inclusion criteria (n = 764 participants at study completion); the majority of participants were men (77%) taking antiretroviral therapy (14/20 included studies). Exercise interventions included PRE alone (8 studies) or a combination of resistive and aerobic exercise (12 studies) ranging from 6 to 52 weeks in duration. Thirty-four meta-analyses were performed. Results demonstrated statistically significant improvements in cardiorespiratory status (maximum oxygen consumption, exercise time), strength (chest press, knee flexion), weight, and body composition (arm and thigh girth, leg muscle area) among exercisers versus non-exercisers. We found no significant differences in change in CD4 count and viral load. We were unable to perform meta-analyses for psychological outcomes however results from individual studies demonstrated improvements in health-related quality of life with exercisers compared with non-exercisers. CONCLUSIONS:Performing progressive resistive exercise (PRE) or a combination of resistive and aerobic exercise at least three times per week for at least six weeks is safe and can lead to improvements in cardiorespiratory fitness, strength, weight, and body composition for adults with HIV. Exercise may be considered a safe and beneficial for enhancing the health of medically stable adults aging with HIV.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
O'Brien KK,Tynan AM,Nixon SA,Glazier RHdoi
10.1186/s12879-017-2342-8subject
Has Abstractpub_date
2017-04-12 00:00:00pages
268issue
1issn
1471-2334pii
10.1186/s12879-017-2342-8journal_volume
17pub_type
杂志文章,meta分析abstract:BACKGROUND:In Ethiopia, measles case-based surveillance was introduced in 2004 as one strategy for measles control by laboratory confirmation of suspected cases. In this article, epidemiological distribution of laboratory-confirmed measles cases were reported from the Southern Nation Nationalities and Peoples Region (S...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-017-2183-5
更新日期:2017-01-19 00:00:00
abstract:BACKGROUND:Hepatitis B virus (HBV) infection is a significant public health problem that may lead to chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC). Approximately 30% of the world's population has been infected with HBV and approximately 350 million (5-6%) are persistent carriers. More than 120 mi...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2334-8-1
更新日期:2008-01-02 00:00:00
abstract:BACKGROUND:Despite the adoption of the provider-initiated HIV testing strategy, the rate of HIV testing is still very low in sub-Saharan Africa. The aim of this study was to assess the factors associated with HIV testing among sexually active women and men in Senegal. Knowledge of HIV status is the gateway to antiretro...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4717-5
更新日期:2019-12-31 00:00:00
abstract:BACKGROUND:Hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a serious public health problem in China. The National Notifiable Disease Surveillance System (NNDSS) was established online by China CDC in 2004 and rodent surveillance sites were adjusted to 40 sites in 22 provinces in 2005. Here we ana...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-14-384
更新日期:2014-07-11 00:00:00
abstract:BACKGROUND:Despite the serious consequences of rubella infection during early pregnancy, very little is known about the rubella seroprevalence in a number of African countries including Burkina Faso. METHODS:Between December 2007 and March 2008 serum samples were collected from 341 pregnant women in Bobo (n = 132, urb...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-164
更新日期:2013-04-04 00:00:00
abstract::Following publication. ...
journal_title:BMC infectious diseases
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12879-019-3739-3
更新日期:2019-03-04 00:00:00
abstract:BACKGROUND:Despite the considerable efforts made to address the issue of brucellosis worldwide, its prevalence in dairy products continues to be difficult to estimate and represents a key public health issue around the world today. The aim of the present study was to better understand the epidemiology of this disease i...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-4946-7
更新日期:2020-03-27 00:00:00
abstract:BACKGROUND:Infection by Staphylococcus aureus (S. aureus) is a major cause of morbidity and mortality. Colonization by S. aureus increases the risk of infection. Little is known about decolonization strategies for S. aureus beyond antibiotics, however probiotics represent a promising alternative. A randomized controlle...
journal_title:BMC infectious diseases
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12879-018-3028-6
更新日期:2018-03-14 00:00:00
abstract:BACKGROUND:HIV infection has been modifying both the epidemiology and outcome of parasitic infections. Hence, this study was undertaken to determine the prevalence of intestinal parasitic infection among people with and without HIV infection and its association with diarrhea and CD4 T-cell count. METHODS:A cross-secti...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-155
更新日期:2009-09-18 00:00:00
abstract:BACKGROUND:DNA fingerprinting of Mycobacterium tuberculosis isolates offers better opportunities to study links between tuberculosis (TB) cases and can highlight relevant issues in urban TB control in low-endemic countries. METHODS:A medium-sized molecular cluster of TB cases with identical DNA fingerprints was used f...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-151
更新日期:2009-09-08 00:00:00
abstract:BACKGROUND:In the last decade, scrub typhus (ST) has been emerging or re-emerging in some areas of Asia, including Guangzhou, one of the most affected endemic areas of ST in China. METHODS:Based on the data on all cases reported in Guangzhou from 2006 to 2014, we characterized the epidemiological features, and identif...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-2153-3
更新日期:2017-01-05 00:00:00
abstract:BACKGROUND:Staphylococcus aureus is associated with human skin and soft tissue infections (SSTIs); however, the involvement of virulence factors in different clinical presentations is unclear. METHODS:We analyzed methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) strains from Taiwan to d...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1630-z
更新日期:2016-06-10 00:00:00
abstract:BACKGROUND:Fear of TB infection is rooted in historical and social memories of the disease, marked by stigma, segregation and exclusion. Healthcare workers (HCWs) face these same fears today, and even seek to hide their TB status when infected. This study sought to investigate factors associated with HCWs fears of acqu...
journal_title:BMC infectious diseases
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12879-019-4115-z
更新日期:2019-05-28 00:00:00
abstract:BACKGROUND:The ocular manifestations of HIV may lead to visual impairment or blindness. In India, patients typically initiate antiretroviral treatment (ART) with low CD4 cell counts when the risk of ocular complications may be high. The objective of this study was to determine the prevalence and types of HIV-associated...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-158
更新日期:2009-09-23 00:00:00
abstract:BACKGROUND:Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen causing female genital tract infection throughout the world. Reinfection with the same serovar, as well as multiple infections with different serovars, occurs in humans. Using a murine model of female C. trachomatis genital trac...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-5-105
更新日期:2005-11-17 00:00:00
abstract:BACKGROUND:Globally, tuberculosis (TB) is the 10th leading cause of death. Despite no country achieved its target, the world health organization (WHO) proposed a 90-90-90 approach to fastening the end TB strategy. Improvement and progression of TB control need good knowledge and a favorable attitude towards the disease...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-05316-9
更新日期:2020-08-05 00:00:00
abstract:BACKGROUND:Factors related to the natural transmission of Ebola virus (EBOV) to humans are still not well defined. Results of previous sero-prevalence studies suggest that circulation of EBOV in human population is common in sub-Saharan Africa. The Efé pygmies living in Democratic Republic of the Congo are known to be ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1607-y
更新日期:2016-06-10 00:00:00
abstract:BACKGROUND:The most optimal antifungal agent for empiric treatment of invasive fungal diseases (IFDs) in febrile neutropenia is controversial. Our objective was evaluate the relative efficacy of antifungals for all-cause mortality, fungal infection-related mortality and treatment response in this population. METHODS:P...
journal_title:BMC infectious diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12879-017-2263-6
更新日期:2017-02-20 00:00:00
abstract:BACKGROUND:The staphylococci are implicated in a variety of human infections; however, many clinical microbiology laboratories in Nigeria do not identify staphylococci (in particular coagulase negative staphylococci - CNS) to the species level. Moreover, data from multi-centre assessment on antibiotic resistance and ep...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-12-286
更新日期:2012-11-02 00:00:00
abstract:BACKGROUND:Mutations in the basic core promoter (BCP) and its adjacent precore (preC) region in HBV genome are common in chronic hepatitis B patients. However, the patterns of mutation combinations in these two regions during chronic infection are less understood. This study focused on single base mutations in BCP and ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-271
更新日期:2010-09-16 00:00:00
abstract:BACKGROUND:The new HIV treatment guidelines in China recommend antiretroviral therapy (ART) for all people living with HIV, but significant gaps in implementation still exist. Pre-exposure prophylaxis (PrEP) can effectively reduce the risk of HIV transmission among men who have sex with men (MSM). This study assessed t...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3516-8
更新日期:2018-11-28 00:00:00
abstract:BACKGROUND:Escherichia coli infections are frequent in ICU patients. The increased resistance to fluoroquinolones and amoxicillin/clavulanate of this pathogen mandates the prescription of broad-spectrum antibiotics such as piperacillin/tazobactam (PIP-TAZ) or third generation cephalosporins (3GC). METHODS:To assess in...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-8-67
更新日期:2008-05-17 00:00:00
abstract:BACKGROUND:As most data on hepatitis in resource-poor countries relate to urban communities, surveys in the rural environment are necessary to determine the 'true' prevalence of these viral infections. We undertook a survey to determine the prevalence of hepatitis B virus (HBV) infection in an apparently healthy rural ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-286
更新日期:2013-06-24 00:00:00
abstract:BACKGROUND:We describe a case of severe Guillain-Barre syndrome (GBS) associated with chronic active hepatitis C and mixed cryoglobulinemia (MC). To our knowledge, this association between GBS and hepatitis C virus (HCV) infection has been rarely reported. CASE PRESENTATION:A 56-year-old man developed symmetrical musc...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4278-7
更新日期:2019-07-17 00:00:00
abstract:BACKGROUND:West Nile virus (WNV) infections have become increasingly prevalent in certain European countries, including Hungary. Although most human infections do not cause severe symptoms, in approximately 1% of cases WNV infections can lead to severe WNV neuroinvasive disease (WNND) and death. The goal of our study w...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-05760-7
更新日期:2021-01-13 00:00:00
abstract:BACKGROUND:In 2007, Park et al. identified a novel serotype among Streptococcus pneumoniae serogroup 6 which they named serotype 6C. The aim of this study was to evaluate with the Neufeld test a novel S. pneumoniae serotype 6C type specific polyclonal antiserum. In addition, serotype 6C isolates found in Denmark in 200...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-282
更新日期:2010-09-24 00:00:00
abstract:BACKGROUND:Bacterial infections are the most frequent complications in patients with malignancy, and the epidemiology of nosocomial infections among cancer patients has changed over time. This study aimed to evaluate the characteristics, antibiotic resistance patterns, and prognosis of nosocomial infections due to mult...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-05181-6
更新日期:2020-06-29 00:00:00
abstract:BACKGROUND:Antiretroviral therapy dramatically reduced HIV-related morbidity and mortality, prolonging the lifespan of HIV-infected patients. Greater duration of infection and exposure to antiretroviral therapy makes these patients susceptible to traditional cardio-metabolic risk factors and pathologies. The optimal di...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3221-7
更新日期:2018-07-06 00:00:00
abstract:BACKGROUND:Inappropriate antibiotic use is linked to the spread of antimicrobial resistance worldwide, but there are limited systemic data on antibiotic utilization in low- and middle-income countries. The purpose of this study was to evaluate the prevalence and patterns of antibiotic prescription in an ambulatory care...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-021-05804-6
更新日期:2021-01-21 00:00:00
abstract:BACKGROUND:In developing countries rotavirus is the leading cause of severe diarrhoea and diarrhoeal deaths in children under 5. Vaccination could greatly alleviate that burden, but in Mexico as in most low- and middle-income countries the decision to add rotavirus vaccine to the national immunisation program will depe...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-8-103
更新日期:2008-07-29 00:00:00