Abstract:
BACKGROUND:In the last decade, scrub typhus (ST) has been emerging or re-emerging in some areas of Asia, including Guangzhou, one of the most affected endemic areas of ST in China. METHODS:Based on the data on all cases reported in Guangzhou from 2006 to 2014, we characterized the epidemiological features, and identified environmental determinants for the spatial distribution of ST using a panel negative binomial model. RESULTS:A total of 4821 scrub typhus cases were reported in Guangzhou during 2006-2014. The annual incidence increased noticeably and the increase was relatively high and rapid in rural townships and among elderly females. The majority of cases (86.8%) occurred during May-October, and farmers constituted the majority of the cases, accounting for 33.9% in urban and 61.6% in rural areas. The number of housekeeper patients had a rapid increment in both rural and urban areas during the study period. Atmospheric pressure and relative humidity with lags of 1 or 2 months, distributions of broadleaved forest and rural township were identified as determinants for the spatiotemporal distribution of scrub typhus. CONCLUSION:Our results indicate that surveillance and public education need to be focused on the elderly farmers in rural areas covered with broadleaf forest in southern China.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Sun Y,Wei YH,Yang Y,Ma Y,de Vlas SJ,Yao HW,Huang Y,Ma MJ,Liu K,Li XN,Li XL,Zhang WH,Fang LQ,Yang ZC,Cao WCdoi
10.1186/s12879-016-2153-3subject
Has Abstractpub_date
2017-01-05 00:00:00pages
13issue
1issn
1471-2334pii
10.1186/s12879-016-2153-3journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Risk of pneumocystosis after discontinuation of primary or secondary prophylaxis among HIV-infected patients before CD4 counts increase to >==200 cells/microL (early discontinuation) after receiving highly active antiretroviral therapy (HAART) is rarely investigated. METHODS:Medical records of 660 HIV-infec...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-126
更新日期:2010-05-21 00:00:00
abstract:BACKGROUND:Chronic infections and associated inflammatory markers are suggested risk factors for cardiovascular disease (CVD). The proinflammatory cytokine, interleukin (IL)-1β, is suggested to play a role in the regulation of local inflammatory responses in both CVD and periodontitis. The leukotoxin from the periodont...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-11-55
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:After antibiotic treatment of Lyme borreliosis, a subset of patients report persistent symptoms, also referred to as post-treatment Lyme disease syndrome. The reported prevalence of persistent symptoms varies considerably, and its pathophysiology is under debate. The LymeProspect study has been designed to i...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-3949-8
更新日期:2019-04-15 00:00:00
abstract:BACKGROUND:Routine culture-based diagnosis of Pseudomonas aeruginosa lung infection in Cystic Fibrosis (CF) patients can be hampered by the phenotypic variability of the microorganism, including its transition to a Viable But Non-Culturable (VBNC) state. The aim of this study was to validate an ecfX-targeting qPCR prot...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3612-9
更新日期:2018-12-27 00:00:00
abstract:BACKGROUND:In critically ill patients the incidence of invasive fungal infections caused by Candida spp. has increased remarkably. Echinocandins are recommended as initial treatment for invasive fungal infections. The safety and efficacy of micafungin compared to caspofungin is similar, but no comparison is made betwee...
journal_title:BMC infectious diseases
pub_type: 临床试验,杂志文章
doi:10.1186/s12879-016-1825-3
更新日期:2016-09-15 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV)-associated tuberculosis deaths have decreased worldwide over the past decade. We sought to evaluate the effect of HIV status on tuberculosis mortality among patients undergoing treatment for tuberculosis in Lima, Peru, a low HIV prevalence setting. METHODS:We conducted a p...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1375-8
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:This report discusses a case of unsuccessful treatment with recombinant factor VIIa (rFVIIa) in off-label use. The need for international guidelines concerning the off-label use of rFVIIa is outlined as well as the need for methods to control the efficacy of rFVIIa objectively. CASE PRESENTATION:54 year old...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-7-34
更新日期:2007-04-26 00:00:00
abstract:BACKGROUND:Achromobacter xylosoxidans (AX) is known for intrinsic resistance to disinfectants. Our laboratory routine surveillance system detected an unexpected rise in AX bloodstream infections in a 2200-bed hospital. An epidemiological investigation was conducted to find the source and disrupt further transmission. ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1909-0
更新日期:2016-10-19 00:00:00
abstract:BACKGROUND:Hepatitis B virus (HBV) DNA levels are crucial for managing chronic hepatitis B (CHB). It was unclear whether Daan real-time polymerase chain reaction test (Daan test) or COBAS TaqMan HBV DNA Test (Cobas TaqMan) was superior in measuring different HBV DNA levels in clinical specimens. METHODS:We enrolled 67...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2334-14-85
更新日期:2014-02-14 00:00:00
abstract:BACKGROUND:The presence of diabetes mellitus increases the risk of several severe infections, but data on its effect on treatment outcomes in patients with nosocomial pneumonia (NP) caused by methicillin-resistant Staphylococcus aureus (MRSA) are limited. METHODS:We retrospectively analyzed data from a double-blind, r...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12879-016-1779-5
更新日期:2016-09-06 00:00:00
abstract:BACKGROUND:Cutaneous leishmaniasis (CL) is an important public health problem in Brazil and in several tropical regions of the world. In the Americas, Brazil is the country with the highest number of registered cases. In Brazil, the state of Minas Gerais has the highest number of cases in the southeastern region. In th...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-3940-4
更新日期:2019-04-11 00:00:00
abstract:BACKGROUND:This study aims to investigate the clinical features of invasive community-acquired Staphylococcus aureus (CA-SA) infection in Chinese children and analyze its molecular features. METHODS:Clinical data and invasive CA-SA isolates were prospectively collected. Pediatric risk of mortality (PRISM) score was us...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-014-0582-4
更新日期:2014-11-07 00:00:00
abstract:BACKGROUND:Adherence of Streptococcus pneumoniae bacteria to lung cells is a first step in the progression from asymptomatic carriage to pneumonia. Adherence abilities vary widely among S. pneumoniae patient isolates. In this study, the binding properties of S. pneumoniae isolates and the effects of binding on activati...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-6-71
更新日期:2006-04-11 00:00:00
abstract:BACKGROUND:Rosacea is an inflammatory disease affecting the central part of face characterized by persistent or recurrent episodes of erythema, papules, pustules and telangiectasias of unknown etiology. Helicobacter pylori (H. pylori) is a gram-negative bacillus, which is one of the main causes of chronic gastritis, ga...
journal_title:BMC infectious diseases
pub_type: 杂志文章,评审
doi:10.1186/s12879-018-3232-4
更新日期:2018-07-11 00:00:00
abstract:BACKGROUND:The link between infection with hepatitis C virus (HCV) and personality disorders (PD) has not been investigated in detail. The aim of this study was to compare the effectiveness of HCV treatment in prisoners with and without PD. METHODS:We performed a prospective multicentre study in inmates from 25 Spanis...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/s12879-015-1102-x
更新日期:2015-08-19 00:00:00
abstract:BACKGROUND:Cervical cancer is the second most common cancer in women worldwide. Infection with certain human papillomavirus (HPV) genotypes is the most important risk factor associated with cervical cancer. This study analysed the distribution of type-specific HPV infection among women with normal and abnormal cytology...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-11-316
更新日期:2011-11-15 00:00:00
abstract:BACKGROUND:Hospital-based surveillance for pneumococcal meningitis has been conducted since January 1996 in the city of Salvador, Brazil. The purpose of this study was to describe the temporal evolution of Penicillin Non-Susceptible Streptococcus pneumoniae (PNSSP) in regards to serotype distributions and clonal divers...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-1049-y
更新日期:2015-07-30 00:00:00
abstract:BACKGROUND:Local understandings of malaria and use of preventive measures-are critical factors in sustained control of malaria. This study assessed caretakers' knowledge on malaria, use of Long Lasting Insecticide Treated Nets (LLINs) and care-seeking behavior for their children's illness in different malaria transmiss...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-017-2731-z
更新日期:2017-09-18 00:00:00
abstract:BACKGROUND:This randomized controlled trial aimed to evaluate whether the serum procalcitonin (PCT) level can be utilized to guide the use of antibiotics in the treatment of acute exacerbations of asthma. METHODS:A total of 293 consecutive patients with suspected asthma attacks from February 2005 to July 2010 particip...
journal_title:BMC infectious diseases
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2334-13-596
更新日期:2013-12-17 00:00:00
abstract:BACKGROUND:Cytopenias are the most common HIV-associated hematological abnormality. Cytopenias have been associated with several factors including sex, race/ethnicity, geographical location and comorbidities such as tuberculosis, hepatitis B infection, fever and oral candidiasis. Cytopenias become more prevalent as HIV...
journal_title:BMC infectious diseases
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2334-14-496
更新日期:2014-09-10 00:00:00
abstract:BACKGROUND:Facial lipoatrophy is a frequently reported condition associated with use of antiretroviral (ARV) drugs. Poly-L-lactic acid (PLLA) acid has been used to correct facial lipoatrophy in people with HIV since 2004 both in Europe and the United States. The objective of this study was to establish, in real life co...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2334-14-474
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Little is known about the prevalence of HIV or HCV in injecting drug users (IDUs) in Serbia and Montenegro. We measured prevalence of antibodies to HIV (anti-HIV) and hepatitis C virus (anti-HCV), and risk factors for anti-HCV, in community-recruited IDUs in Belgrade and Podgorica, and determined the perform...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-14
更新日期:2009-02-09 00:00:00
abstract:BACKGROUND:Between November 2 and 10, 2002 several patients with psoriasis and personnel staying in the health centre in Gran Canaria, Spain fell ill with diarrhoea, vomiting or both. Patient original came from Norway, Sweden and Finland. The patient group was scheduled to stay until 8 November. A new group of patients...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-4-45
更新日期:2004-10-29 00:00:00
abstract:BACKGROUND:The inflammasome responses in Treponema pallidum infection have been poorly understood to date. This study aimed to investigate the expression of the nucleotide-binding leucine-rich receptor protein 3 (NLRP3) inflammasome in the development of tissue inflammation in rabbits infected with T. pallidum. METHOD...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-2993-0
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Australia is developing a chlamydia screening program. This study aimed to determine the attitudes of young women to the introduction of chlamydia screening in Australian General Practice. METHODS:In-depth face-to-face interviews with 24 young women from across Victoria, Australia, attending a randomly sele...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-8-62
更新日期:2008-05-09 00:00:00
abstract:BACKGROUND:Dengue is a major public health problem in tropical and subtropical countries. Rapid and easy diagnosis of dengue can assist patient triage and care-management. The detection of DENV NS1 on rapid lateral flow tests offers a fast route to a presumptive dengue diagnosis but careful evaluations are urgently nee...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-142
更新日期:2010-05-28 00:00:00
abstract:BACKGROUND:In West and Central Africa areas of endemic Loa loa infections overlap with regions of high prevalence of human immunodeficiency virus type 1 (HIV-1) infections. Because individuals in this region are exposed to filarial parasites from birth, most HIV-1 infected individuals invariably also have a history of ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3072-2
更新日期:2018-04-04 00:00:00
abstract:BACKGROUND:Following delivery by caesarean section, surgical site infection is the most common infectious complication. Despite a large number of caesarean sections performed at Debre Markos Referral Hospital, there was no study documenting the incidence of surgical site infection after caesarean section. Therefore, th...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-05640-0
更新日期:2020-11-30 00:00:00
abstract:BACKGROUND:Bacterial infections in the genital tract frequently result in morbidity through a variety of inflammation based symptoms. One component of the bacteria that may trigger host inflammatory response is their DNA. CpG motifs in this DNA are known targets for Toll-like receptor 9 (TLR9), which is a pathogen-reco...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-1016-7
更新日期:2015-07-16 00:00:00
abstract:BACKGROUND:The Belgian HIV epidemic is largely concentrated among men who have sex with men and Sub-Saharan Africans. We studied the continuum of HIV care of those diagnosed with HIV living in Belgium and its associated factors. METHODS:Data on new HIV diagnoses 2007-2010 and HIV-infected patients in care in 2010-2011...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-1230-3
更新日期:2015-11-03 00:00:00