Abstract:
BACKGROUND:Rosacea is an inflammatory disease affecting the central part of face characterized by persistent or recurrent episodes of erythema, papules, pustules and telangiectasias of unknown etiology. Helicobacter pylori (H. pylori) is a gram-negative bacillus, which is one of the main causes of chronic gastritis, gastric cancer and gastrointestinal ulcers. Recent evidences have suggested that H. pylori infection is closely related to the occurrence of diseases. In recent years, studies have found that Helicobacter pylori infection is associated with the occurrence of acne rosacea. So the treatment of Helicobacter pylori infection may be a therapeutic method of acne rosacea. But it continues to be controversial. In other studies, the treatment of Helicobacter pylori did not significantly reduce the severity of acne rosacea. To further explore the association between acne rosacea and Helicobacter pylori infection, a summarize method was used to study the relationship between acne rosacea and Helicobacter pylori, providing reference for clinical acne rosacea therapy. METHODS:Systematic searches were conducted on Wanfang Data, CQVIP, Springer, Public Health Management Corporation (PHMC), CNKI, and Pubmed, from January 1,2008 to Mar. 1, 2018, using Helicobacter pylori and rosacea to retrieve the literature. Depending on the inclusion and exclusion criteria, 27 articles considered or confirmed the correlation between H. pylori and rosacea. RESULTS:Epidemiological investigations and experiments have confirmed that H. pylori infection is associated with the development of rosacea. The effect of anti-H. pylori therapy is better than the routine therapy for rosacea. H. pylori can stimulate the immune system to produce a large number of inflammatory mediators, leading to the occurrence and aggravation of rosacea inflammation. CONCLUSIONS:It is confirmed that H. pylori infection is involved in the development of rosacea. It is suggested that rosacea patients should be tested for H. pylori infection, the H. pylori-positive rosacea patients should be treated with eradication of H. pylori, so as to enhance the therapeutic effect of rosacea. This study adds that H. pylori infection is involved in the development of rosacea. Epidemiological investigations and experiments have confirmed the rationality. The effect of anti-H. pylori therapy is better than the routine therapy for rosacea. H. pylori-positive rosacea patients should be treated with the therapeutic method of eradication of H. pylori.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Yang Xdoi
10.1186/s12879-018-3232-4subject
Has Abstractpub_date
2018-07-11 00:00:00pages
318issue
1issn
1471-2334pii
10.1186/s12879-018-3232-4journal_volume
18pub_type
杂志文章,评审abstract:BACKGROUND:Chronic hepatitis C virus (HCV) infection can progress to cirrhosis and end-stage liver disease in a substantial proportion of patients. The infection is frequently asymptomatic, leaving many infected individuals unaware of the diagnosis until complications occur. This advocates the screening of healthy indi...
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pub_type: 杂志文章
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abstract:BACKGROUND:Human papillomavirus (HPV) and HIV are each responsible for a considerable burden of disease. Interactions between these infections pose substantial public health challenges, especially where HIV prevalence is high and HPV vaccine coverage low. METHODS:Between July 2005 and January 2006, a cross-sectional c...
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pub_type: 杂志文章
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更新日期:2010-01-26 00:00:00
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更新日期:2013-06-05 00:00:00
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更新日期:2013-03-11 00:00:00
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pub_type: 杂志文章
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更新日期:2005-09-21 00:00:00
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pub_type: 杂志文章
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更新日期:2015-02-03 00:00:00
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更新日期:2013-05-02 00:00:00
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更新日期:2004-08-31 00:00:00
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更新日期:2018-04-10 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2019-02-06 00:00:00
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doi:10.1186/s12879-016-1665-1
更新日期:2016-07-22 00:00:00
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更新日期:2013-08-27 00:00:00
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更新日期:2019-04-11 00:00:00
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pub_type: 杂志文章
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更新日期:2017-01-07 00:00:00
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更新日期:2017-05-23 00:00:00
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更新日期:2017-10-02 00:00:00
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章
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更新日期:2015-04-17 00:00:00
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更新日期:2020-05-24 00:00:00
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