Differential activation of inflammatory pathways in A549 type II pneumocytes by Streptococcus pneumoniae strains with different adherence properties.

abstract：BACKGROUND:Retaining patients on antiretroviral treatment in care is critical to sustaining the 90:90:90 vision. Nigeria has made some progress in placing HIV-positive patients on treatment. In an effort to increase access to treatment, ART decentralization has been implemented in the country. This is aimed at strength...

journal_title：BMC infectious diseases

authors： Umeokonkwo CD,Onoka CA,Agu PA,Ossai EN,Balogun MS,Ogbonnaya LU

更新日期：2019-07-22 00:00:00

abstract：BACKGROUND:Procalcitonin (PCT) is an inflammatory marker that has been used as indicator of severe bacterial infection. We evaluated the concentrations of PCT as a marker for systemic infection compared to C-reactive protein (CRP) in patients neutropenic febrile. METHODS:52 adult patients were enrolled in the study. B...

journal_title：BMC infectious diseases

authors： Massaro KS,Costa SF,Leone C,Chamone DA

更新日期：2007-11-22 00:00:00

abstract：BACKGROUND:Soft tissue or skin infections due to nontuberculous mycobacteria (NTM) have been reported frequently and are mostly associated with trauma or cosmetic interventions like plastic surgery. However, infection with NTM as a result of a dental procedure have rarely been described and the lack of clinical suspici...

journal_title：BMC infectious diseases

authors： Pérez-Alfonzo R,Poleo Brito LE,Vergara MS,Ruiz Damasco A,Meneses Rodríguez PL,Kannee Quintero CE,Carrera Martinez C,Rivera-Oliver IA,Da Mata Jardin OJ,Rodríguez-Castillo BA,de Waard JH

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Provision of information plays a critical role in supporting patients to be engaged or empowered to be involved with infection prevention measures in hospitals. This explorative study evaluated the suitability, readability and accessibility of information on healthcare associated infections (HCAIs) and infec...

journal_title：BMC infectious diseases

authors： Park J,Seale H

更新日期：2017-12-21 00:00:00

abstract：BACKGROUND:Chronic infections and associated inflammatory markers are suggested risk factors for cardiovascular disease (CVD). The proinflammatory cytokine, interleukin (IL)-1β, is suggested to play a role in the regulation of local inflammatory responses in both CVD and periodontitis. The leukotoxin from the periodont...

journal_title：BMC infectious diseases

authors： Johansson A,Eriksson M,Ahrén AM,Boman K,Jansson JH,Hallmans G,Johansson I

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Growing evidence suggests respiratory syncytial virus (RSV) is an important cause of respiratory disease in adults. However, the adult burden remains largely uncharacterized as most RSV studies focus on children, and population-based studies with laboratory-confirmation of infection are difficult to implemen...

journal_title：BMC infectious diseases

authors： Fleming DM,Taylor RJ,Lustig RL,Schuck-Paim C,Haguinet F,Webb DJ,Logie J,Matias G,Taylor S

更新日期：2015-10-23 00:00:00

abstract：BACKGROUND:Lemierre's syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction. CASE PRESENTATION:A 17-year old female, with no previous medical hist...

journal_title：BMC infectious diseases

authors： Constantin JM,Mira JP,Guerin R,Cayot-Constantin S,Lesens O,Gourdon F,Romaszko JP,Linval P,Laurichesse H,Bazin JE

更新日期：2006-07-17 00:00:00

abstract：BACKGROUND:Oxidative stress plays a vital role in the pathogenesis of both Sickle Cell Disease (SCD) and Plasmodium falciparum malaria. However, there are limited studies on the effect of P. falciparum malaria infection on oxidative stress in SCD patients. METHODS:A cross-sectional study was undertaken to compare leve...

journal_title：BMC infectious diseases

authors： Atiku SM,Louise N,Kasozi DM

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:To determine the prevalence of carriage of respiratory bacterial pathogens, and the risk factors for and serotype distribution of pneumococcal carriage in an Australian Aboriginal population. METHODS:Surveys of nasopharyngeal carriage of Streptococcus pneumoniae, non-typeable Haemophilus influenzae, and Mor...

journal_title：BMC infectious diseases

authors： Mackenzie GA,Leach AJ,Carapetis JR,Fisher J,Morris PS

更新日期：2010-10-23 00:00:00

abstract：BACKGROUND:Nitric oxide (NO*) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO* resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases. METHODS:In this study we evaluated the in vitro toxicity of nitric oxide for the promastigote st...

journal_title：BMC infectious diseases

authors： Giudice A,Camada I,Leopoldo PT,Pereira JM,Riley LW,Wilson ME,Ho JL,de Jesus AR,Carvalho EM,Almeida RP

更新日期：2007-02-22 00:00:00

abstract：BACKGROUND:The federal state of Hesse, Germany, introduced a laboratory-based reporting scheme for carbapenem-resistant organisms (CROs). METHOD:The results of the first year of mandated reporting of CROs from April 2012 through March 2013 to the Public Health Authority of Frankfurt/Main, responsible for a population ...

journal_title：BMC infectious diseases

authors： Kleinkauf N,Hausemann A,Kempf VA,Gottschalk R,Heudorf U

更新日期：2014-08-19 00:00:00

abstract：BACKGROUND:Spinal neuroschistosomiasis (SN) is one of the most severe clinical presentations of schistosomiasis infection and an ectopic form of the disease caused by any species of Schistosoma. In Brazil, all cases of this clinical manifestation are related to Schistosoma mansoni, the only species present in the count...

journal_title：BMC infectious diseases

authors： Domingues ALC,Barbosa CS,Agt TFA,Mota AB,Franco CMR,Lopes EP,Loyo R,Gomes ECS

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:Early infant diagnosis of HIV infection is challenging in sub-Saharan Africa, particularly in rural areas, leading to delays in diagnosis and treatment. Use of a point-of-care test would overcome many challenges. This study evaluated the validity of a novel point-of-care p24 antigen detection test (LYNX) in ...

journal_title：BMC infectious diseases

authors： Sutcliffe CG,Mutanga J,Moyo N,Agarwal AK,Schue JL,Hamahuwa M,Palamountain KM,Fisher MJ,Elghanian R,Thuma PE,Moss WJ

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:Septic shock is a common and often devastating syndrome marked by severe cardiovascular dysfunction commonly managed with vasopressors. Whether markers of heart rate complexity before vasopressor up-titration could be used to predict success of the up-titration is not known. METHODS:We studied patients with...

journal_title：BMC infectious diseases

authors： Brown SM,Sorensen J,Lanspa MJ,Rondina MT,Grissom CK,Shahul S,Mathews VJ

更新日期：2016-10-10 00:00:00

abstract：BACKGROUND:PCRctic is an innovative assay based on 16S rDNA PCR technology that has been designed to detect a single intact bacterium in a specimen of cerebro-spinal fluid (CSF). The assay's potential for accurate, fast and inexpensive discrimination of bacteria-free CSF makes it an ideal adjunct for confident exclusio...

journal_title：BMC infectious diseases

authors： Abelian A,Mund T,Curran MD,Savill SA,Mitra N,Charan C,Ogilvy-Stuart AL,Pelham HRB,Dear PH

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:The rapid identification of acid-fast bacilli recovered from patient specimens as Mycobacterium tuberculosis complex (MTC) is critically important for accurate diagnosis and treatment. A thin-layer immunochromatographic (TLC) assay using anti-MPB64 or anti-MPT64 monoclonal antibodies was developed to discrim...

journal_title：BMC infectious diseases

authors： Chikamatsu K,Aono A,Yamada H,Sugamoto T,Kato T,Kazumi Y,Tamai K,Yanagisawa H,Mitarai S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Rapid influenza diagnosis is important for early identification of outbreaks, effective management of high-risk contacts, appropriate antiviral use, decreased inappropriate antibiotic use and avoidance of unnecessary laboratory testing. Given the inconsistent performance of many rapid influenza tests, clinic...

journal_title：BMC infectious diseases

authors： Woolpert T,Brodine S,Lemus H,Waalen J,Blair P,Faix D

更新日期：2012-06-07 00:00:00

abstract：BACKGROUND:Dose-response assessment is one step in quantitative microbial risk assessment (QMRA). Four infectious microbes capable of causing respiratory diseases important to public health, and for which dose-response functions have not been available are: Bordetella pertussis (whooping cough), group A Streptococcus (...

journal_title：BMC infectious diseases

authors： Jones RM,Su YM

更新日期：2015-02-24 00:00:00

abstract：BACKGROUND:Because of the high prevalence and absence of cure for infection, chronic hepatitis B virus (HBV) infection has been acknowledged as a pressing public health issue. Toll-like receptors (TLRs) activate the human innate immune system and the polymorphisms in TLRs may alter their function. The present study aim...

journal_title：BMC infectious diseases

authors： Lin Y,Gao ZX,Shen X,Chen MJ,Li YT,Li SL,Lin HL,Zhao QF,Liu F,Niu JJ

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Clinical outcomes of spontaneous bacterial peritonitis (SBP) due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK) have not been adequately investigated. METHODS:We conducted a retrospective matched case-control study to evaluate the outcomes of SBP due to ESBL-...

journal_title：BMC infectious diseases

authors： Song KH,Jeon JH,Park WB,Park SW,Kim HB,Oh MD,Lee HS,Kim NJ,Choe KW

更新日期：2009-04-12 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen resistance to antibiotics including methicillin. The resistance first emerged in 1960 in a healthcare setting only after two years of using methicillin as a viable treatment for methicillin-susceptible Staphylococcus aureus. MRSA lead...

journal_title：BMC infectious diseases

authors： Wagner R,Agusto FB

更新日期：2018-02-07 00:00:00

abstract：BACKGROUND:The outbreak of the novel coronavirus (COVID-19) that was firstly reported in Wuhan, China, with cases now confirmed in more than 100 countries. However, COVID-19 pneumonia with spontaneous pneumothorax is unknown. CASE PRESENTATION:We reported a case of 66-year-old man infected with COVID-19, presenting wi...

journal_title：BMC infectious diseases

authors： Chen X,Zhang G,Tang Y,Peng Z,Pan H

更新日期：2020-09-09 00:00:00

abstract：BACKGROUND:Daptomycin is a rapidly bactericidal agent with broad coverage against Gram-positive organisms, including Staphylococcus aureus, the most frequent cause of osteomyelitis. The objective of this study was to describe the clinical outcome of patients with non-hardware associated osteomyelitis, and the safety pr...

journal_title：BMC infectious diseases

authors： Gallagher JC,Huntington JA,Culshaw D,McConnell SA,Yoon M,Berbari E

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:Fatigue is a common symptom of chronic hepatitis C virus (HCV) infection and a frequent side-effect of peginterferon/ribavirin (PR) therapy for HCV. This study evaluated the impact of adding the oral HCV NS3/4A protease inhibitor simeprevir to PR on patient-reported fatigue and health status among patients w...

journal_title：BMC infectious diseases

authors： Scott J,Rosa K,Fu M,Cerri K,Peeters M,Beumont M,Zeuzem S,Evon DM,Gilles L

更新日期：2014-08-26 00:00:00

abstract：BACKGROUND:Estimates of Human Papillomavirus (HPV) prevalence in a population prior to and after HPV vaccine introduction are essential to evaluate the short-term impact of vaccination. METHODS:Between 2010 and 2012 we conducted a population-based cross-sectional study in Germany to determine HPV prevalence, genotype ...

journal_title：BMC infectious diseases

authors： Deleré Y,Remschmidt C,Leuschner J,Schuster M,Fesenfeld M,Schneider A,Wichmann O,Kaufmann AM

更新日期：2014-02-19 00:00:00

abstract：BACKGROUND:Extended use of oseltamivir in an immunocompromised host could reportedly induce neuraminidase gene mutation possibly leading to oseltamivir-resistant influenza A/H3N2 virus. To our knowledge, no report is available on the clinical course of a severely immunocompromised patient with a dual E119D/R292K neuram...

journal_title：BMC infectious diseases

authors： Harada N,Shibata W,Koh H,Takashita E,Fujisaki S,Okamura H,Nanno S,Yamada K,Nakamae H,Hino M,Kakeya H

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:People successfully completing treatment for tuberculosis remain at elevated risk for recurrent disease, either from relapse or reinfection. Identifying risk factors for recurrent tuberculosis may help target post-tuberculosis screening and care. METHODS:We enrolled 500 patients with smear-positive pulmonar...

journal_title：BMC infectious diseases

authors： Cudahy PGT,Wilson D,Cohen T

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:Antimicrobial resistance in Mycoplasma genitalium is rising globally with resultant clinical treatment failure. We investigated the prevalence of mutations in the macrolide and fluoroquinolone resistance-determining regions of M. genitalium in Johannesburg, South Africa, and ascertained their association wit...

journal_title：BMC infectious diseases

authors： Muller EE,Mahlangu MP,Lewis DA,Kularatne RS

更新日期：2019-02-13 00:00:00

abstract：BACKGROUND:The presence of hydrogen peroxide (H(2)O(2)) producing Lactobacillus in the vagina may play a role in controlling genital HIV-1 shedding. Sensitive molecular methods improve our ability to characterize the vaginal microbiota; however, they cannot characterize phenotype. We assessed the concordance of H(2)O(2...

journal_title：BMC infectious diseases

authors： Balkus JE,Mitchell C,Agnew K,Liu C,Fiedler T,Cohn SE,Luque A,Coombs R,Fredricks DN,Hitti J

更新日期：2012-08-13 00:00:00

abstract：BACKGROUND:Intracranial infection after puncture of cerebral hematoma in patients with intracerebral hemorrhage is very common in the department of neurosurgery, yet the relevant risks remain unknown. We attempted to analyze the risk factors of intracranial infection after puncture of cerebral hematoma, to provide insi...

journal_title：BMC infectious diseases

authors： Han H,Li Y,Liu L,Liu N,Wang Y,Zhang M

更新日期：2020-12-11 00:00:00