Disseminated Saksenaea infection in an immunocompromised host associated with a good clinical outcome: a case report and review of the literature.

Abstract:

BACKGROUND:Saksenaea species (spp.) are uncommon causes of mucormycosis but are emerging pathogens mostly associated with trauma and soil contamination often in immunocompetent hosts. Due to lack of sporulation in the laboratory, diagnosis and susceptibility testing is difficult so optimal treatment regimens are unknown. CASE PRESENTATION:A 67 year-old man from the Northern Territory in Australia, with a history of eosinophilic granulomatosis with polyangiitis, developed disseminated Saksenaea infection after initially presenting with symptoms consistent with bacterial pyelonephritis. Despite a delay in diagnosis; with aggressive surgical management and dual therapy with amphotericin B and posaconazole, he survived. CONCLUSIONS:We describe an unusual case of disseminated infection with a favourable outcome to date.

journal_name

BMC Infect Dis

journal_title

BMC infectious diseases

authors

Davidson N,Campbell K,Foroughi F,Tayal V,Lynar S,Crawford LC,Kidd SE,Baird R,Davies J,Meumann EM

doi

10.1186/s12879-020-05459-9

subject

Has Abstract

pub_date

2020-10-14 00:00:00

pages

755

issue

1

issn

1471-2334

pii

10.1186/s12879-020-05459-9

journal_volume

20

pub_type

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