Circulating granulysin levels in healthcare workers and latent tuberculosis infection estimated using interferon-gamma release assays.

abstract：BACKGROUND:Vitamin D enhances host protective immune responses to Mycobacterium tuberculosis by suppressing Interferon-gamma (IFN-g) and reducing disease associated inflammation in the host. The objectives of this study were to determine whether vitamin D supplementation to patients with tuberculosis (TB) could influen...

journal_title：BMC infectious diseases

authors： Salahuddin N,Ali F,Hasan Z,Rao N,Aqeel M,Mahmood F

更新日期：2013-01-19 00:00:00

abstract：BACKGROUND:Direct immunofluorescence assays (DFA) are a rapid and inexpensive method for the detection of respiratory viruses and may therefore be used for surveillance. Few epidemiological studies have been published based solely on DFA and none included respiratory picornaviruses and human metapneumovirus (hMPV). We ...

journal_title：BMC infectious diseases

authors： Sadeghi CD,Aebi C,Gorgievski-Hrisoho M,Mühlemann K,Barbani MT

更新日期：2011-02-07 00:00:00

abstract：BACKGROUND:In order to investigate the epidemiology, molecular characteristics, and distribution of extended-spectrum β-lactamase (ESBL)- and AmpC-producing Escherichia coli from community-onset infections in Chinese county hospitals. METHODS:E. coli isolates were collected from patients with community-onset infection...

journal_title：BMC infectious diseases

authors： Zhang J,Zheng B,Zhao L,Wei Z,Ji J,Li L,Xiao Y

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:Diabetes is a risk factor for infection with coronaviruses. This study describes the demographic, clinical data, and outcomes of critically ill patients with diabetes and Middle East Respiratory Syndrome (MERS). METHODS:This retrospective cohort study was conducted at 14 hospitals in Saudi Arabia (September...

journal_title：BMC infectious diseases

authors： Jose J,Al-Dorzi HM,Al-Omari A,Mandourah Y,Al-Hameed F,Sadat M,Al Qasim E,Alraddadi B,Al Harthy A,Al Mekhlafi GA,Almotairi A,Al Khatib K,Abdulmomen A,Qushmaq I,Sindi AA,Mady A,Solaiman O,Al-Raddadi R,Maghrabi K,Ragab

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:There have been no reports regarding clinical features and molecular characteristics of childhood methicillin-susceptible Staphylococcus aureus (MSSA) infections in Taiwan. METHODS:We prospectively collected clinical S. aureus isolates from patients aged < 18 years in a university-affiliated hospital in 201...

journal_title：BMC infectious diseases

authors： Chen YJ,Chen PA,Chen CJ,Huang YC

更新日期：2019-05-10 00:00:00

abstract：BACKGROUND:Although early presentation to HIV-care is essential to ensure timely initiation of antiretroviral therapy, recent studies have shown that especially migrants present to HIV-care at a later stage of HIV-infection. Currently, thirty percent of all newly diagnosed HIV cases in Germany originate from abroad. So...

journal_title：BMC infectious diseases

authors： Zeitlmann N,Gunsenheimer-Bartmeyer B,Santos-Hövener C,Kollan C,An der Heiden M,ClinSurv Study Group.

更新日期：2016-12-07 00:00:00

abstract：BACKGROUND:Microscopic examination of peripheral blood smear produces reliable results both about the malaria infection status and level of parasitemia. However, test results are affected by skill of the laboratory personnel, workload, condition of microscopes and quality of laboratory supplies. Therefore, continuous m...

journal_title：BMC infectious diseases

authors： Tegegne B,Ejigu K,Alemu G,Fetene Y,Endaylalu K,Melese M

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:In comparison to restriction fragment length polymorphism (RFLP) typing, variable number of tandem repeat (VNTR) typing is easier to perform, faster and yields results in a simple, numerical format. Therefore, this technique has gained recognition as the new international gold standard in typing of Mycobacte...

journal_title：BMC infectious diseases

authors： Huyen MN,Kremer K,Lan NT,Buu TN,Cobelens FG,Tiemersma EW,de Haas P,van Soolingen D

更新日期：2013-02-02 00:00:00

abstract：BACKGROUND:It is widely assumed that voluntary counselling and testing (VCT) services contribute to HIV prevention by motivating clients to reduce sexual risk-taking. However, findings from sub-Saharan Africa have been mixed, particularly among HIV-negative persons. We explored associations between VCT use and changes ...

journal_title：BMC infectious diseases

authors： Cawley C,Wringe A,Slaymaker E,Todd J,Michael D,Kumugola Y,Urassa M,Zaba B

更新日期：2014-03-22 00:00:00

abstract：BACKGROUND:Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of developing opportunistic infections or re-activation of latent infections, with higher associated morbidity and mortality. The aim of this quality improvement ...

journal_title：BMC infectious diseases

authors： Chadwick DR,Sayeed L,Rose M,Budd E,Mohammed M,Harrison S,Azad J,Maddox J

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:For a long time, the role of CD8(+) T cells in blood-stage malaria was not considered important because erythrocytes do not express major histocompatibility complex (MHC) class I proteins. While recent evidences suggest that CD8(+) T cells may play an important role during the erythrocytic phase of infection...

journal_title：BMC infectious diseases

authors： Hojo-Souza NS,Pereira DB,Passos LS,Gazzinelli-Guimarães PH,Cardoso MS,Tada MS,Zanini GM,Bartholomeu DC,Fujiwara RT,Bueno LL

更新日期：2015-01-31 00:00:00

abstract：BACKGROUND:Non-adherence to tuberculosis (TB) treatment is the most important cause of poor TB outcomes, and improving support for TB patients is a primary priority for governments, but there has been little research on the effects of family, social and national policy support factors on TB treatment adherence. The cur...

journal_title：BMC infectious diseases

authors： Chen X,Du L,Wu R,Xu J,Ji H,Zhang Y,Zhu X,Zhou L

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Inappropriate antibiotic use is linked to the spread of antimicrobial resistance worldwide, but there are limited systemic data on antibiotic utilization in low- and middle-income countries. The purpose of this study was to evaluate the prevalence and patterns of antibiotic prescription in an ambulatory care...

journal_title：BMC infectious diseases

authors： Zhang HL,Bodinayake C,Wijayaratne GB,Jayatissa P,Piyasiri DLB,Kurukulasooriya R,Sheng T,Nagahawatte A,Woods C,Tillekeratne LG

更新日期：2021-01-21 00:00:00

abstract：:The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single dose rifampicin (SDR) as post-exposure prophylaxis (PEP) for contacts of leprosy patients, reduces their risk to develop leprosy by 60%. This...

journal_title：BMC infectious diseases

authors： Mieras LF,Taal AT,van Brakel WH,Cambau E,Saunderson PR,Smith WCS,Prakoeswa CRS,Astari L,Scollard DM,do Nascimento DC,Grosset J,Kar HK,Izumi S,Gillini L,Virmond MCL,Sturkenboom MGG

更新日期：2018-10-05 00:00:00

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF-α) plays a key role in the containment of tuberculosis. The relationship between the TNF -238G/A polymorphism and tuberculosis susceptibility remains inconclusive. A comprehensive meta-analysis was made to provide a more precise estimate of the relationship between them. MET...

journal_title：BMC infectious diseases

authors： Zhang Z,Zhu H,Pu X,Meng S,Zhang F,Xun L,Liu Q,Wang Y

更新日期：2012-11-28 00:00:00

abstract：BACKGROUND:Pandemic influenza vaccine manufacturing capacity and distribution agility is enhanced through the availability of equivalent antigen-sparing vaccines. We evaluated equivalence in terms of immunogenicity between GlaxoSmithKline Vaccines' A/California/7/2009 (H1N1)v-like-AS03 vaccines manufactured in Dresden ...

journal_title：BMC infectious diseases

authors： Launay O,Duval X,Fitoussi S,Jilg W,Kerdpanich A,Montellano M,Schwarz TF,Watanveerade V,Wenzel JJ,Zalcman G,Bambure V,Li P,Caplanusi A,Madan A,Gillard P,Vaughn DW

更新日期：2013-09-16 00:00:00

abstract：BACKGROUND:The ocular manifestations of HIV may lead to visual impairment or blindness. In India, patients typically initiate antiretroviral treatment (ART) with low CD4 cell counts when the risk of ocular complications may be high. The objective of this study was to determine the prevalence and types of HIV-associated...

journal_title：BMC infectious diseases

authors： Pathai S,Deshpande A,Gilbert C,Lawn SD

更新日期：2009-09-23 00:00:00

abstract：BACKGROUND:Community-genotype methicillin-resistant Staphylococcus aureus (CG-MRSA) clones are a global concern due to their resistance and increased virulence and their ability to cause infections both hospitalized patients and healthy people in the community. Here, we characterize 32 isolates of a new CG-MRSA clone. ...

journal_title：BMC infectious diseases

authors： Escobar-Perez J,Reyes N,Marquez-Ortiz RA,Rebollo J,Pinzón H,Tovar C,Moreno-Castañeda J,Corredor ZL,Castro BE,Moncada MV,Vanegas N

更新日期：2017-01-31 00:00:00

abstract：:The study of hepatitis C virus (HCV) genotypes/subtypes, quasispecies and recombinants obtained by virus genome sequencing are important for epidemiological studies, to trace the source of infection, for development of new direct acting antivirals (DAAs) therapy and for understanding antiviral selection pressures. The...

journal_title：BMC infectious diseases

authors： Marascio N,Torti C,Liberto M,Focà A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Neonatal sepsis is one of the major causes of death during the first month of life and early empirical treatment with injectable antibiotics is a life-saving intervention. Adherence to World Health Organisation guidelines on first line antibiotics is crucial to mitigate the risks of increased antimicrobial r...

journal_title：BMC infectious diseases

authors： Ekman B,Paudel P,Basnet O,Kc A,Wrammert J

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Dengue fever and leptospirosis have partially overlapping geographic distributions, similar clinical presentations and potentially life-threatening complications but require different treatments. Distinguishing between these cosmopolitan emerging pathogens represents a diagnostic dilemma of global importance...

journal_title：BMC infectious diseases

authors： Conroy AL,Gélvez M,Hawkes M,Rajwans N,Liles WC,Villar-Centeno LA,Kain KC

更新日期：2014-01-20 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) continues to be a public health challenge in Saudi Arabia, particularly for the elderly. This study was conducted to estimate mortality per 1000 person-year among TB and resistant TB cases and to identifying factors associated with mortality. METHODS:This is a retrospective cohort study of...

journal_title：BMC infectious diseases

authors： Aljadani R,Ahmed AE,Al-Jahdali H

更新日期：2019-05-16 00:00:00

abstract：BACKGROUND:Temporary increases in plasma HIV RNA ('blips') are common in HIV patients on combination antiretroviral therapy (cART). Blips above 500 copies/mL have been associated with subsequent viral rebound. It is not clear if this relationship still holds when measurements are made using newer more sensitive assays....

journal_title：BMC infectious diseases

authors： Young J,Rickenbach M,Calmy A,Bernasconi E,Staehelin C,Schmid P,Cavassini M,Battegay M,Günthard HF,Bucher HC,Swiss HIV Cohort Study.

更新日期：2015-09-21 00:00:00

abstract：BACKGROUND:Hospital-based surveillance for pneumococcal meningitis has been conducted since January 1996 in the city of Salvador, Brazil. The purpose of this study was to describe the temporal evolution of Penicillin Non-Susceptible Streptococcus pneumoniae (PNSSP) in regards to serotype distributions and clonal divers...

journal_title：BMC infectious diseases

authors： dos Santos MS,Azevedo J,Menezes AP,Cordeiro SM,Escobar EC,Lima JB,Campos LC,Carvalho Mda G,Reis MG,Ko AI,Reis JN

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:The central-line associated bloodstream infections (CLABSI) are the most common healthcare-associated infections in childhood. Despite the international data available on healthcare-associated infections in selected groups of patients, there is a lack of large and good quality studies. The present survey is ...

journal_title：BMC infectious diseases

authors： Venturini E,Montagnani C,Benni A,Becciani S,Biermann KP,De Masi S,Chiappini E,de Martino M,Galli L,CLABSI (central-line associated bloodstream infections) study group.

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Undernutrition is one of the most common problems among people living with HIV, contributing to premature death and the development of comorbidities within this population. In Sub-Saharan Africa (SSA), the impacts of these often inter-related conditions appear in a series of fragmented and inconclusive studi...

journal_title：BMC infectious diseases

authors： Alebel A,Demant D,Petrucka P,Sibbritt D

更新日期：2021-01-04 00:00:00

abstract：BACKGROUND:Mycobacterium goodii is a rare cause of significant infection. M. goodii has mainly been associated with lymphadenitis, cellulitis, osteomyelitis, and wound infection. CASE PRESENTATION:A case of a 76-year-old Caucasian female is presented. The patient developed a prosthetic valve endocarditis caused by M. ...

journal_title：BMC infectious diseases

authors： Jönsson G,Rydberg J,Sturegård E,Christensson B

更新日期：2012-11-14 00:00:00

abstract：BACKGROUND:The swine influenza H1N1 first identified in Mexico, spread rapidly across the globe and is considered the fastest moving pandemic in history. The early phase of an outbreak, in which data is relatively scarce, presents scientific challenges on key issues such as: scale, severity and immunity which are funda...

journal_title：BMC infectious diseases

authors： Roll U,Yaari R,Katriel G,Barnea O,Stone L,Mendelson E,Mandelboim M,Huppert A

更新日期：2011-04-14 00:00:00

abstract：BACKGROUND:Middle East Respiratory Syndrome (MERS) is caused by MERS coronavirus (MERS-CoV). More than 80% of reported cases have occurred in Saudi Arabia, with a mortality exceeding 50%. Health-care workers (HCWs) are at risk of acquiring and transmitting this virus, so the concerns of HCWs in Saudi Arabia regarding M...

journal_title：BMC infectious diseases

authors： Abolfotouh MA,AlQarni AA,Al-Ghamdi SM,Salam M,Al-Assiri MH,Balkhy HH

更新日期：2017-01-03 00:00:00

abstract：BACKGROUND:Erythema induratum of Bazin (EIB) - nodular vasculitis associated with Mycobacterium tuberculosis (TB) - and Tuberculosis-Associated Ocular Inflammation (TB-AOI) represent uncommon manifestations of TB. There is limited data and a lack of diagnostic and treatment standards for these conditions. METHODS:Elev...

journal_title：BMC infectious diseases

authors： Connors WJ,Fisher DA,Kunimoto DY,Jarand JM

更新日期：2019-01-29 00:00:00