Increased brain cortical thickness associated with visceral fat in adolescents.

Abstract:

BACKGROUND:There has been a growing amount of evidence indicating that excess visceral fat is associated with alterations in brain structure and function, including brain cortical thinning in adults. OBJECTIVES:This study aims to investigate the relationship between brain cortical thickness with obesity assessments, in adolescents. METHODS:In this study, we measured three different obesity assessments within an adolescent population (aged 15 - 18 years): body mass index (BMI), visceral fat ratio measured with an MRI and hepatorenal gradient measured with an ultrasound. Volunteers also underwent an MRI scan to measure brain structure. RESULTS:Results indicated that there was no relationship of BMI or hepatorenal gradient with brain cortical dimensions. However, there was a significant association between visceral fat ratio and an increase of cortical thickness throughout the brain. CONCLUSIONS:These results suggest that visceral fat, but not BMI, is correlated with cortical thickening in adolescence.

journal_name

Pediatr Obes

journal_title

Pediatric obesity

authors

Saute RL,Soder RB,Alves Filho JO,Baldisserotto M,Franco AR

doi

10.1111/ijpo.12190

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

74-77

issue

1

eissn

2047-6302

issn

2047-6310

journal_volume

13

pub_type

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