Impact of obesity on outcomes of paediatric acute pancreatitis based on a national administrative database.

Abstract:

BACKGROUND:Insufficient information is available on the relationship between obesity and outcome of paediatric patients with acute pancreatitis. OBJECTIVES:This study aimed to investigate the effect of obesity on outcomes of paediatric patients with acute pancreatitis based on a national administrative database. METHODS:A total of 500 cases in 416 paediatric patients with acute pancreatitis (aged 5-17 years) were referred from 260 hospitals between 2010 and 2012 in Japan. Patients were divided into two groups according to the presence of obesity: with obesity (n = 65) and without obesity (n = 435). Patient data were collected from the administrative database to compare the prevalence of severe acute pancreatitis, in-hospital mortality, length of stay (LOS) and medical costs between the groups. RESULTS:Both prevalence of severe acute pancreatitis and in-hospital mortality were significantly higher in paediatric patients with obesity than those without (36.9% vs. 16.3% and 3.1% vs. 0.0%; P < 0.001, respectively). Longer LOS and higher medical costs were also observed in paediatric patients with obesity (25.7 vs. 15.2 days, P < 0.001 and 14 169.5 vs. 7457.7 US dollars, P < 0.001, respectively). CONCLUSION:This study demonstrated that obesity significantly influenced the outcomes of paediatric acute pancreatitis.

journal_name

Pediatr Obes

journal_title

Pediatric obesity

authors

Murata A,Ohtani M,Muramatsu K,Kobori S,Tomioka S,Matsuda S

doi

10.1111/ijpo.12041

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

174-80

issue

3

eissn

2047-6302

issn

2047-6310

journal_volume

11

pub_type

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