Abstract:
BACKGROUND/OBJECTIVE:We evaluated the prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in 27 adolescents referred for weight loss surgery (WLS). RESULTS:On biopsy, 18 patients (66.7%) had NAFLD, and of those, 10 (37.0%) had NASH and 11 (40.7%) had fibrosis. Insulin, HbA1C and homeostatic model assessment of insulin resistance (HOMA-IR) were significantly higher in patients with NASH than those without NASH. Following WLS, 40% of patients with NASH had persistently elevated aminotransferase levels despite weight loss. CONCLUSION:We found that NASH is underdiagnosed in adolescents referred for WLS, and that hyperinsulinaemia, HOMA-IR and HbA1c can aid in identifying high-risk patients.
journal_name
Pediatr Obesjournal_title
Pediatric obesityauthors
Corey KE,Stanley TL,Misdraji J,Scirica C,Pratt J,Hoppin A,Misra Mdoi
10.1111/j.2047-6310.2014.219.xsubject
Has Abstractpub_date
2014-10-01 00:00:00pages
e91-3issue
5eissn
2047-6302issn
2047-6310journal_volume
9pub_type
杂志文章abstract:BACKGROUND:Overt or subclinical hypothyroidism is a common finding in adult populations affected by non-alcoholic fatty liver disease (NAFLD). Currently, there are only sparse data available on the association of thyroid dysfunction and NAFLD in obese children and adolescents. OBJECTIVE:The study aims to investigate t...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12110
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to establish, through measured height and weight, the prevalence of overweight and obesity in a representative sample of Maltese children aged 10-11 years. METHODS:Height and weight were measured in a sample, stratified by sex, region and type of school, of 874 year 6 children...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2013.00191.x
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Genetic and epigenetic variations may be an important contributer to altered eating behaviors in childhood which may lead to weight gain and obesity later in life. OBJECTIVE:This study aimed to evaluate epigenetic as well as genetic associations with appetite in young children. SUBJECTS AND METHODS:Partici...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12010
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Obesity is a global health concern but the United States has reported a leveling in obesity rates in the pediatric population. OBJECTIVE:To provide updated waist circumference (WC) percentile values, identify differences across time and discuss differences within the context of reported weight stabilization...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12150
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to investigate changes in volatile organic compounds (VOCs) in exhaled breath in overweight/obese children compared with their lean counterparts. STUDY DESIGN:Single exhaled breath was collected and analyzed per protocol using selective ion flow tube mass spectrometry (SIFT-MS...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2014.221.x
更新日期:2015-02-01 00:00:00
abstract::Childhood obesity monitoring is a fundamental component of obesity prevention but is poorly done in Australia. Monitoring obesity prevalence in children provides important population health data that can be used to track trends over time, identify areas at greatest risk of obesity, determine the effectiveness of inter...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00076.x
更新日期:2012-10-01 00:00:00
abstract::The association between total dietary fat intake and measures of body fatness in children with obesity remains inconsistent. This study aimed to determine whether dietary long-chain polyunsaturated fatty acids (LCPUFA) and LCPUFA status relate to body composition in children with obesity. Children (n = 63, 9.0 ± 0.2 y...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12689
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Previous studies have indicated that snacking is contributing to increased calorie intake of American children and that the energy density of snacks in US diets has increased in recent decades. OBJECTIVE:Examine short-term and long-term trends in the energy density and food sources of snacks for US children...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12220
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The Healthy Communities Study (HCS) was a national study of community programs and policies that aimed to address childhood obesity; it necessitated recruitment of a large sample of children from communities throughout the United States. OBJECTIVE:The HCS aimed to complete visits with an average of 45 child...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12455
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The data regarding prospective associations between physical activity (PA) and adiposity in youth are inconsistent. OBJECTIVE:The objective of this study was to investigate associations between baseline levels of objectively measured PA and changes in adiposity over 2.5 years from mid-to-late adolescence. ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12031
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:Sagittal diameter (SAD) has been reported to correlate to visceral fat and cardiovascular risk factors. SAD is measured with the individual lying down, halfway between the lower rib margin and the iliac crest; it represents the mid-height of the abdomen. The aim of this study was to validate SAD measured usi...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00095.x
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Pediatric obesity impacts on multiple domains of psychological health, including self-esteem and body image. OBJECTIVE:To determine the effect of multicomponent pediatric obesity treatment interventions on self-esteem and body image. METHODS:A systematic search of published literature up to June 2019 was u...
journal_title:Pediatric obesity
pub_type: 杂志文章,meta分析
doi:10.1111/ijpo.12600
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Early childhood temperament is increasingly recognized as an important attribute that may impact screen time use, outdoor play and childhood obesity. The relationship between temperament and nutrition in preschool children is less clear. OBJECTIVE:The objective of the study is to investigate if temperament ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12161
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:The effect of the patatin-like phospholipase domain containing 3 gene (PNPLA3) I148M polymorphism on the risk and severity of paediatric and adolescent nonalcoholic fatty liver disease (NAFLD) remains inconclusive. OBJECTIVES:We aimed to estimate the effect of this polymorphism not only on early-onset NAFLD...
journal_title:Pediatric obesity
pub_type: 杂志文章,meta分析
doi:10.1111/ijpo.12615
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Obesity in children is considered the main childhood health problem. OBJECTIVE:To assess the impact of 7-year community-based interventions on the trend prevalence of overweight and obesity in French preschool children and primary school children between 2008 and 2015. METHODS:Two cross-sectional studies w...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12761
更新日期:2020-12-17 00:00:00
abstract:BACKGROUND:Executive functioning (EF) difficulties may be associated with problems regulating eating behaviours. Few studies have evaluated this question in youth using diverse measures of EF or objective measures of energy intake. METHODS:The current study used neuropsychological tasks and a laboratory test meal to e...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12614
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Non-alcoholic fatty liver disease (NAFLD), prediabetes and type 2 diabetes mellitus are known to be closely linked with obesity as early as during childhood. OBJECTIVES:The study aimed to determine the prevalence of prediabetes and T2DM in children with obesity with or without increased transaminases. METH...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12601
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:In adults, adherence to the Mediterranean diet has been inversely associated with cardiovascular risk, but the extent to which diet in pregnancy is associated with offspring adiposity is unclear. We aimed to investigate the association between adherence to Mediterranean diet in pregnancy and offspring cardio...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12191
更新日期:2017-08-01 00:00:00
abstract:UNLABELLED:What is already known about this subject Children born to women with gestational diabetes have greater risk for obesity. Obesity in adults and children is associated with blunted postprandial gut hormone responses. What this study adds Children of women with gestational diabetes have a blunted postprandial r...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00140.x
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:Growing evidence indicates that ambient (AAP: NO2 , PM2.5 and O3 ) and traffic-related air pollutants (TRAP) contribute to metabolic disease risk in adults; however, few studies have examined these relationships in children. METHODS:Metabolic profiling was performed in 429 overweight and obese African-Ameri...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12188
更新日期:2018-01-01 00:00:00
abstract::Mobile health (mHealth) is a relatively nascent field, with a variety of technologies being explored and developed. Because of the explosive growth in this field, it is of interest to examine the design, development and efficacy of various interventions as research becomes available. This systematic review examines cu...
journal_title:Pediatric obesity
pub_type: 杂志文章,评审
doi:10.1111/ijpo.12002
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Child obesity is a growing public health concern. Excess weight in childhood is known to be associated with a high risk of obesity and obesity-related comorbidities in adulthood. OBJECTIVES:This study quantifies lifetime excess costs of overweight and obese adults in Germany taking the history of obesity in...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.278
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:This study investigated if levels of allostatic load (ALoad) differed according to race/ethnicity in children and if ALoad was associated with obesity-related measures. METHODS:A multiethnic sample of 307 children aged seven to 12 was evaluated, composed of 39% European American (EA), 35% African American (A...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12501
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:The prevalence of obesity in childhood is of high concern, especially in deprived populations. We explored trends in obesity following the introduction of a citywide strategy focused on preschool children. METHODS:Analysis of obesity prevalence using the National Child Measurement Programme 2009 to 2017 for...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12529
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to examine the relationship between diet and inflammation, and adiposity in minority youth. DESIGN AND METHODS:The study was designed as a cross-sectional analysis of 142 overweight (≥85th body mass index percentile) Hispanic and African-American adolescents (14-18 years) with...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12017
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Increases in portion size are thought by many to promote obesity in children. However, this relationship remains unclear. Here, we explore the extent to which a child's BMI is predicted both by parental beliefs about their child's ideal and maximum portion size and/or by the child's own beliefs. METHODS:Par...
journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijpo.12218
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Obesity is a risk factor for asthma. However, it is unclear if increased obesity prevalence contributed to rising childhood asthma prevalence. OBJECTIVE:To assess if population-level changes in weight status impacted asthma prevalence over time. METHODS:Using nationally representative 1988-2014 National He...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12246
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Drink personalization (featuring names on bottle labels) has been used by soft drink companies to make their drinks attractive to children, potentially increasing consumption. To date, no publically available research has evaluated the influence of personalization on children's drink choices. OBJECTIVES:To ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12193
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Weight/length (W/L) indices are poor surrogates for adiposity in preterm infants born appropriate for gestational age (AGA) at birth, but whether the association subsequently improves is unknown. OBJECTIVE:To determine if W/L indices accurately reflect adiposity in premature infants born AGA in later infanc...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12744
更新日期:2020-11-03 00:00:00
abstract:BACKGROUND:Few studies have assessed how well body mass index (BMI), waist circumference (WC), or waist to height ratio (WtHR) perform in identifying cardio-metabolic risk among youth. OBJECTIVE:The objective of this study was to evaluate the utility of BMI and WC percentiles and WtHR to distinguish adolescents with a...
journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijpo.267
更新日期:2015-10-01 00:00:00