Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review.

Abstract:

BACKGROUND:The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. METHODS:We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. DISCUSSION:The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

journal_name

Clin Transl Allergy

authors

Dhami S,Nurmatov U,Pajno GB,Fernandez-Rivas M,Muraro A,Roberts G,Akdis C,Alvaro-Lozano M,Beyer K,Bindslev-Jensen C,Burks W,du Toit G,Ebisawa M,Eigenmann P,Knol E,Makela M,Nadeau KC,O'Mahony L,Papadopoulos N,Poulsen

doi

10.1186/s13601-016-0113-z

subject

Has Abstract

pub_date

2016-07-05 00:00:00

pages

24

issn

2045-7022

pii

113

journal_volume

6

pub_type

杂志文章
  • Dual exposure to smoking and household air pollution is associated with an increased risk of severe asthma in adults in Brazil.

    abstract:Background:The relationship between smoking, household pollution, dual exposure and severity of asthma in adults has not been sufficiently studied. We examined and compared the effects of cigarette smoking, domestic wood burning pollution and dual exposure (tobacco and wood burning) upon asthma severity in adults. Met...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-018-0235-6

    authors: Fernandes AGO,de Souza-Machado C,Pinheiro GP,de Oliva ST,Mota RCL,de Lima VB,Cruz CS,Chatkin JM,Cruz ÁA

    更新日期:2018-12-10 00:00:00

  • Having concomitant asthma phenotypes is common and independently relates to poor lung function in NHANES 2007-2012.

    abstract:Background:Evidence for distinct asthma phenotypes and their overlap is becoming increasingly relevant to identify personalized and targeted therapeutic strategies. In this study, we aimed to describe the overlap of five commonly reported asthma phenotypes in US adults with current asthma and assess its association wit...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-018-0201-3

    authors: Amaral R,Fonseca JA,Jacinto T,Pereira AM,Malinovschi A,Janson C,Alving K

    更新日期:2018-05-04 00:00:00

  • Cow's milk allergy in Dutch children: an epigenetic pilot survey.

    abstract:BACKGROUND:Cow's milk allergy (CMA) is a common disease in infancy. Early environmental factors are likely to contribute to CMA. It is known that epigenetic gene regulation can be altered by environmental factors. We have set up a proof of concept study, aiming to detect epigenetic associations specific with CMA. METH...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-016-0105-z

    authors: Petrus NCM,Henneman P,Venema A,Mul A,van Sinderen F,Haagmans M,Mook O,Hennekam RC,Sprikkelman AB,Mannens M

    更新日期:2016-05-04 00:00:00

  • Protocol for a double-blind randomised controlled trial of low dose intradermal grass pollen immunotherapy versus a histamine control on symptoms and medication use in adults with seasonal allergic rhinitis (PollenLITE).

    abstract:BACKGROUND:Subcutaneous immunotherapy with high dose grass pollen (typically microgram quantities) was first described over 100 years ago. This treatment suppresses allergen-induced cutaneous late responses, with lesser effects on early responses. We previously reported that repeated 2-weekly intradermal injections of ...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/2045-7022-3-27

    authors: Slovick A,Douiri A,Kelly J,Guerra A,Muir R,Tsioulos K,Murphy C,Shamji MH,Ying S,Durham SR,Till SJ

    更新日期:2013-08-21 00:00:00

  • Protease resistance of food proteins: a mixed picture for predicting allergenicity but a useful tool for assessing exposure.

    abstract:Background:Susceptibility to pepsin digestion of candidate transgene products is regarded an important parameter in the weight-of-evidence approach for allergenicity risk assessment of genetically modified crops. It has been argued that protocols used for this assessment should better reflect physiological conditions e...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-018-0216-9

    authors: Akkerdaas J,Totis M,Barnett B,Bell E,Davis T,Edrington T,Glenn K,Graser G,Herman R,Knulst A,Ladics G,McClain S,Poulsen LK,Ranjan R,Rascle JB,Serrano H,Speijer D,Wang R,Pereira Mouriès L,Capt A,van Ree R

    更新日期:2018-08-10 00:00:00

  • Correction to: Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper.

    abstract::[This corrects the article DOI: 10.1186/s13601-019-0303-6.]. ...

    journal_title:Clinical and translational allergy

    pub_type: 已发布勘误

    doi:10.1186/s13601-020-00343-w

    authors: Hox V,Lourijsen E,Jordens A,Aasbjerg K,Agache I,Alobid I,Bachert C,Boussery K,Campo P,Fokkens W,Hellings P,Hopkins C,Klimek L,Mäkelä M,Mösges R,Mullol J,Pujols L,Rondon C,Rudenko M,Toppila-Salmi S,Scadding G,Sch

    更新日期:2020-09-28 00:00:00

  • Allergic rhinitis in northern vietnam: increased risk of urban living according to a large population survey.

    abstract:BACKGROUND:Little is known about prevalence and risk factors of allergic rhinitis and chronic nasal symptoms among adults in Vietnam. We aimed to estimate the prevalence, risk factor patterns and co-morbidities of allergic rhinitis and chronic nasal symptoms in one urban and one rural area in northern Vietnam. METHODS...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/2045-7022-1-7

    authors: Lâm HT,Văn T Tng N,Ekerljung L,Rönmark E,Lundbäck B

    更新日期:2011-08-11 00:00:00

  • Is a positive intracutaneous test induced by penicillin mediated by histamine? A cutaneous microdialysis study in penicillin-allergic patients.

    abstract:Background:Diagnostic workup of penicillin allergy comprises skin testing with penicillins, and patients are deemed allergic if skin test is positive. However, the literature suggests that skin test-positive patients may be challenge-negative, indicating that the skin test may be falsely positive. Objective:To investi...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-017-0179-2

    authors: Tannert LK,Falkencrone S,Mortz CG,Bindslev-Jensen C,Skov PS

    更新日期:2017-11-17 00:00:00

  • Indoleamine 2,3-dioxygenase expression in patients with allergic rhinitis: a case-control study.

    abstract:BACKGROUND:Indoleamine 2,3-dioxygenase (IDO) is a tryptophan catalyzing enzyme. It has been suggested that it has a role in lower airway allergic inflammations, but its role in allergic rhinitis has not been investigated. OBJECTIVE:Our aim was to evaluate the expression of IDO in the nasal mucosa of allergic rhinitis ...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/2045-7022-1-17

    authors: Luukkainen A,Karjalainen J,Honkanen T,Lehtonen M,Paavonen T,Toppila-Salmi S

    更新日期:2011-12-12 00:00:00

  • Cosmetics for neonates and infants: haptens in products' composition.

    abstract::Cosmetics and skin care products for neonates and infants are considered as ''hypoallergenic'', "tested" or ''safe''. Nevertheless, the prevalence of haptens in these products is a matter of concern, since allergic contact dermatitis in children is gaining an importance. We aimed to assess the prevalence of haptens in...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-019-0257-8

    authors: Dumycz K,Kunkiel K,Feleszko W

    更新日期:2019-03-08 00:00:00

  • The association between airborne pollen monitoring and sensitization in the hot desert climate.

    abstract:Background:Pollen is a major cause of allergic respiratory diseases. In Qatar, data on the presence and prevalence of allergenic airborne types of pollen is quite limited. Methods:The study aimed to determine and correlate the most frequently implicated airborne pollen detected by aerobiological monitoring samplers in...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-020-00339-6

    authors: Al-Nesf MA,Gharbi D,Mobayed HM,Dason BR,Mohammed Ali R,Taha S,Tuffaha A,Adeli M,Sattar HA,Trigo MDM

    更新日期:2020-08-10 00:00:00

  • Prospective validation of the "rhino conjunctivitis allergy-control-SCORE©" (RC-ACS©).

    abstract:BACKGROUND:Recently we reported the validation of the "Allergy-Control-SCORE© (ACS)" which assesses symptom severity as well as medication use on three dimensions lung, nose and eyes. The aim of this study was to test the validity of the score for eyes and nose. METHODS:One-hundred-twenty-one consenting subjects (age ...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/2045-7022-2-17

    authors: Häfner D,Reich K,Zschocke I,Lotzin A,Meyer H,Kettner J,Narkus A

    更新日期:2012-09-19 00:00:00

  • Drug-related relapses in drug reaction with eosinophilia and systemic symptoms (DRESS).

    abstract:BACKGROUND:A drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T cell mediated hypersensitivity reaction. Relapses of symptoms in the recovery phase are frequent and linked to the reduction of the corticosteroid treatment, to viral reactivations or to the exposure to new drugs. Here, we analyzed...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-020-00359-2

    authors: Jörg L,Helbling A,Yerly D,Pichler WJ

    更新日期:2020-11-23 00:00:00

  • Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

    abstract::[This corrects the article DOI: 10.1186/s13601-016-0116-9.]. ...

    journal_title:Clinical and translational allergy

    pub_type: 已发布勘误

    doi:10.1186/s13601-016-0135-6

    authors: Bousquet J,Farrell J,Crooks G,Hellings P,Bel EH,Bewick M,Chavannes NH,de Sousa JC,Cruz AA,Haahtela T,Joos G,Khaltaev N,Malva J,Muraro A,Nogues M,Palkonen S,Pedersen S,Robalo-Cordeiro C,Samolinski B,Strandberg T,Va

    更新日期:2017-02-20 00:00:00

  • Eosinophilic disorders: evaluation of current classification and diagnostic criteria, proposal of a practical diagnostic algorithm.

    abstract::Eosinophilic disorders represent a group of pathologic conditions with highly heterogeneous pathophysiology and clinical presentation and variable prognosis, ranging from asymptomatic or mild, to severe and complex cases, with fatal outcome. Interest in this group of disorders has increased during the last two decades...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章,评审

    doi:10.1186/s13601-019-0277-4

    authors: Leru PM

    更新日期:2019-07-25 00:00:00

  • Sesame oleosins are minor allergens.

    abstract:Background:In daily practice, one-third of sesame allergic patients, confirmed by clinical history or food challenge, do not show any detectable specific IgE using current diagnostics. Currently used sesame extracts are water-based and therefore lacking hydrophobic proteins like oleosins. Oleosins, the stabilizer of li...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-019-0271-x

    authors: Ehlers AM,Rossnagel M,Brix B,Blankestijn MA,Le TM,Suer W,Otten HG,Knulst AC

    更新日期:2019-06-28 00:00:00

  • Lung function in severe pediatric asthma: a longitudinal study in children and adolescents in Brazil.

    abstract:Background:In severe asthma, high doses of inhaled corticosteroids (ICS) are used in order to achieve clinical and functional control. This study aimed to evaluate lung function in outpatients (children and adolescents) with severe asthma in Brazil, all of whom were treated with high doses of ICS. We evaluated all spir...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-017-0183-6

    authors: Versiani Nunes Pinheiro de Queiroz M,Gonçalves Alvim C,Cruz ÁA,de Lima Belizário Facury Lasmar LM

    更新日期:2017-12-15 00:00:00

  • Food allergy in a child with de novo KAT6A mutation.

    abstract::Crying combined with miscellaneous gastrointestinal symptoms are typical symptoms of infant with food allergy, but are also common among children with abnormal neurological development. Mutations in KAT6A gene is known to cause a syndrome characterized by developmental delay, hypotonia, cardiac defects, microcephaly, ...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-017-0155-x

    authors: Elenius V,Lähdesmäki T,Hietala M,Jartti T

    更新日期:2017-06-22 00:00:00

  • The placebo effect in allergen-specific immunotherapy trials.

    abstract:BACKGROUND:Double-blind, placebo-controlled (DBPC) trials are the gold standard for demonstrating clinical efficacy and tolerability. The placebo effect, although an important feature in placebo-controlled studies, has never been systematically investigated in allergen-specific immunotherapy (SIT) studies. This study w...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/2045-7022-3-42

    authors: Narkus A,Lehnigk U,Haefner D,Klinger R,Pfaar O,Worm M

    更新日期:2013-12-21 00:00:00

  • Relationship between vitamin D and chronic spontaneous urticaria: a systematic review.

    abstract:Background:Vitamin D has been reported to be associated with many allergic diseases. There are a limited number of the studies of vitamin D supplementation in patients with chronic spontaneous urticaria (CSU). This study aims to study the relationship between vitamin D and CSU in terms of serum vitamin D levels, and th...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-018-0234-7

    authors: Tuchinda P,Kulthanan K,Chularojanamontri L,Arunkajohnsak S,Sriussadaporn S

    更新日期:2018-12-04 00:00:00

  • Prolonged efficacy of the 300IR 5-grass pollen tablet up to 2 years after treatment cessation, as measured by a recommended daily combined score.

    abstract:BACKGROUND:The 300IR (index of reactivity) 5-grass pollen tablet has favorable short-term and sustained clinical efficacy in patients with grass pollen-induced allergic rhinoconjunctivitis (ARC). Here, we report maintenance of efficacy and safety over 2 years following treatment discontinuation. METHODS:Randomized, do...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-015-0057-8

    authors: Didier A,Malling HJ,Worm M,Horak F,Sussman GL

    更新日期:2015-05-22 00:00:00

  • Stevens-Johnson syndrome/toxic epidermal necrolysis and erythema multiforme drug-related hospitalisations in a national administrative database.

    abstract:Background:Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and erythema multiforme (EM) are immunologically-mediated dermatological disorders commonly triggered by drug exposure and/or other external agents. We aimed to characterise SJS/TEN- and EM-drug-related hospitalisations in a nationwide administrat...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-017-0188-1

    authors: Sousa-Pinto B,Araújo L,Freitas A,Correia O,Delgado L

    更新日期:2018-01-22 00:00:00

  • European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases: report of the European Union Parliament Summit (29 March 2017).

    abstract::On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European Parliament of Brussels and was hosted by MEP David Borrelli and MEP Sirpa ...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章,评审

    doi:10.1186/s13601-017-0186-3

    authors: Hellings PW,Borrelli D,Pietikainen S,Agache I,Akdis C,Bachert C,Bewick M,Botjes E,Constantinidis J,Fokkens W,Haahtela T,Hopkins C,Illario M,Joos G,Lund V,Muraro A,Pugin B,Seys S,Somekh D,Stjärne P,Valiulis A,Val

    更新日期:2017-12-27 00:00:00

  • Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins.

    abstract:BACKGROUND:The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathophysiological processes and the currently available biological tools for ...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章,评审

    doi:10.1186/s13601-017-0152-0

    authors: van Bilsen JHM,Sienkiewicz-Szłapka E,Lozano-Ojalvo D,Willemsen LEM,Antunes CM,Molina E,Smit JJ,Wróblewska B,Wichers HJ,Knol EF,Ladics GS,Pieters RHH,Denery-Papini S,Vissers YM,Bavaro SL,Larré C,Verhoeckx KCM,Roggen EL

    更新日期:2017-05-12 00:00:00

  • Association of elevated fractional exhaled nitric oxide concentration and blood eosinophil count with severe asthma exacerbations.

    abstract:Background:Blood eosinophil count (BEC) and fractional exhaled nitric oxide (FeNO) concentration are established biomarkers in asthma, associated particularly with the risk of exacerbations. We evaluated the relationship of BEC and FeNO as complementary and independent biomarkers of severe asthma exacerbations. Method...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-019-0282-7

    authors: Price DB,Bosnic-Anticevich S,Pavord ID,Roche N,Halpin DMG,Bjermer L,Usmani OS,Brusselle G,Ming SWY,Rastogi S

    更新日期:2019-08-21 00:00:00

  • Health Related Quality of Life among schoolchildren aged 12-13 years in relation to food hypersensitivity phenotypes: a population-based study.

    abstract:BACKGROUND:While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The aim of this study was to investigate Health Related Quality of Life (HRQL) in children with and withou...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-017-0156-9

    authors: Strinnholm Å,Hedman L,Winberg A,Jansson SA,Lindh V,Rönmark E

    更新日期:2017-07-03 00:00:00

  • Preventing food allergy: protocol for a rapid systematic review.

    abstract:BACKGROUND:The European Academy of Allergy and Clinical Immunology is developing guidelines about how to prevent and manage food allergy. As part of the guidelines development process, a systematic review is planned to examine published research about the prevention of food allergy. This systematic review is one of sev...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/2045-7022-3-10

    authors: de Silva D,Panesar SS,Thusu S,Rader T,Halken S,Muraro A,Sheikh A

    更新日期:2013-03-28 00:00:00

  • Sinus computed tomography predicts clinical response to corticosteroids in chronic rhinosinusitis with nasal polyps.

    abstract:Background:Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease usually characterized by chronic eosinophilia in the sinonasal mucosa, which often requires glucocorticoid (GC) therapy. However, the therapeutic response varies markedly between individuals. The objective of this study...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-018-0211-1

    authors: Hong H,Wang D,Tan KS,Zheng R,Chen F,Gao W,He H,Shi J,Fan Y,Yang Q,Sun Y

    更新日期:2018-07-02 00:00:00

  • Study of atopic multimorbidity in subjects with rhinitis using multiplex allergen component analysis.

    abstract:Background:Rhinitis is a common problem within the population. Many subjects with rhinitis also have atopic multimorbidity, such as asthma and eczema. The purpose of this investigation was to compare subjects with only rhinitis to those that have rhinitis, asthma and/or eczema in relation to immunoglobulin E (IgE) sens...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-020-0311-6

    authors: Blöndal V,Sundbom F,Borres MP,Högman M,Alving K,Malinovschi A,Janson C

    更新日期:2020-02-21 00:00:00

  • Distinct type 2-high inflammation associated molecular signatures of chronic rhinosinusitis with nasal polyps with comorbid asthma.

    abstract:Background:Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and comorbid asthma have more severe disease and are difficult to treat. However, the molecular endotypes associated with CRSwNP with comorbid asthma (CRSwNP + AS) are not clear. This study aimed to investigate the characteristics of type 2 infl...

    journal_title:Clinical and translational allergy

    pub_type: 杂志文章

    doi:10.1186/s13601-020-00332-z

    authors: Wang M,Bu X,Luan G,Lin L,Wang Y,Jin J,Zhang L,Wang C

    更新日期:2020-07-03 00:00:00