Food allergy in a child with de novo KAT6A mutation.

abstract：Background:Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease usually characterized by chronic eosinophilia in the sinonasal mucosa, which often requires glucocorticoid (GC) therapy. However, the therapeutic response varies markedly between individuals. The objective of this study...

journal_title：Clinical and translational allergy

authors： Hong H,Wang D,Tan KS,Zheng R,Chen F,Gao W,He H,Shi J,Fan Y,Yang Q,Sun Y

更新日期：2018-07-02 00:00:00

abstract：BACKGROUND:Although efforts to improve the classification of hypersensitivity/allergic diseases have been made, they have not been considered a top-level category in the International Classification of Diseases (ICD)-10 and still are not in the ICD-11 beta phase linearization. ICD-10 is the most used classification sys...

journal_title：Clinical and translational allergy

authors： Tanno LK,Calderon MA,Goldberg BJ,Akdis CA,Papadopoulos NG,Demoly P

更新日期：2014-11-28 00:00:00

abstract：Background:Susceptibility to pepsin digestion of candidate transgene products is regarded an important parameter in the weight-of-evidence approach for allergenicity risk assessment of genetically modified crops. It has been argued that protocols used for this assessment should better reflect physiological conditions e...

journal_title：Clinical and translational allergy

authors： Akkerdaas J,Totis M,Barnett B,Bell E,Davis T,Edrington T,Glenn K,Graser G,Herman R,Knulst A,Ladics G,McClain S,Poulsen LK,Ranjan R,Rascle JB,Serrano H,Speijer D,Wang R,Pereira Mouriès L,Capt A,van Ree R

更新日期：2018-08-10 00:00:00

abstract：Background:Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and comorbid asthma have more severe disease and are difficult to treat. However, the molecular endotypes associated with CRSwNP with comorbid asthma (CRSwNP + AS) are not clear. This study aimed to investigate the characteristics of type 2 infl...

journal_title：Clinical and translational allergy

authors： Wang M,Bu X,Luan G,Lin L,Wang Y,Jin J,Zhang L,Wang C

更新日期：2020-07-03 00:00:00

abstract：BACKGROUND:Double-blind, placebo-controlled (DBPC) trials are the gold standard for demonstrating clinical efficacy and tolerability. The placebo effect, although an important feature in placebo-controlled studies, has never been systematically investigated in allergen-specific immunotherapy (SIT) studies. This study w...

journal_title：Clinical and translational allergy

authors： Narkus A,Lehnigk U,Haefner D,Klinger R,Pfaar O,Worm M

更新日期：2013-12-21 00:00:00

abstract：BACKGROUND:The European Academy of Allergy and Clinical Immunology is developing guidelines about how to prevent and manage food allergy. As part of the guidelines development process, a systematic review is planned to examine published research about the prevention of food allergy. This systematic review is one of sev...

journal_title：Clinical and translational allergy

authors： de Silva D,Panesar SS,Thusu S,Rader T,Halken S,Muraro A,Sheikh A

更新日期：2013-03-28 00:00:00

abstract：:Cosmetics and skin care products for neonates and infants are considered as ''hypoallergenic'', "tested" or ''safe''. Nevertheless, the prevalence of haptens in these products is a matter of concern, since allergic contact dermatitis in children is gaining an importance. We aimed to assess the prevalence of haptens in...

journal_title：Clinical and translational allergy

authors： Dumycz K,Kunkiel K,Feleszko W

更新日期：2019-03-08 00:00:00

abstract：BACKGROUND:For the development of forecasts for seasonal allergic rhinitis symptoms, it is essential to understand the relationship between grass pollen concentrations and the symptoms of grass pollen allergic patients. OBJECTIVE:The aim of this study was to delineate this relationship between seasonal allergic rhinit...

journal_title：Clinical and translational allergy

authors： de Weger LA,Beerthuizen T,Gast-Strookman JM,van der Plas DT,Terreehorst I,Hiemstra PS,Sont JK

更新日期：2011-12-21 00:00:00

abstract：:Drug hypersensitivity reactions (DHR) have been present since the advent of drugs. In particular T-cell mediated delayed-type hypersensitivity reactions represent a heterogeneous clinical entity with a diverse pathogenesis and result in a considerable burden of morbidity and mortality not only driven by the reactions ...

journal_title：Clinical and translational allergy

authors： Schrijvers R,Gilissen L,Chiriac AM,Demoly P

更新日期：2015-09-03 00:00:00

abstract：:[This corrects the article DOI: 10.1186/s13601-019-0303-6.]. ...

journal_title：Clinical and translational allergy

authors： Hox V,Lourijsen E,Jordens A,Aasbjerg K,Agache I,Alobid I,Bachert C,Boussery K,Campo P,Fokkens W,Hellings P,Hopkins C,Klimek L,Mäkelä M,Mösges R,Mullol J,Pujols L,Rondon C,Rudenko M,Toppila-Salmi S,Scadding G,Sch

更新日期：2020-09-28 00:00:00

abstract：:Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30% of the total population, hence being associated with an important socio-economic burden. Different phenotypes of rhinitis and CRS...

journal_title：Clinical and translational allergy

authors： De Greve G,Hellings PW,Fokkens WJ,Pugin B,Steelant B,Seys SF

更新日期：2017-07-12 00:00:00

abstract：Background:Diagnostic workup of penicillin allergy comprises skin testing with penicillins, and patients are deemed allergic if skin test is positive. However, the literature suggests that skin test-positive patients may be challenge-negative, indicating that the skin test may be falsely positive. Objective:To investi...

journal_title：Clinical and translational allergy

authors： Tannert LK,Falkencrone S,Mortz CG,Bindslev-Jensen C,Skov PS

更新日期：2017-11-17 00:00:00

abstract：:[This corrects the article DOI: 10.1186/s13601-016-0116-9.]. ...

journal_title：Clinical and translational allergy

authors： Bousquet J,Farrell J,Crooks G,Hellings P,Bel EH,Bewick M,Chavannes NH,de Sousa JC,Cruz AA,Haahtela T,Joos G,Khaltaev N,Malva J,Muraro A,Nogues M,Palkonen S,Pedersen S,Robalo-Cordeiro C,Samolinski B,Strandberg T,Va

更新日期：2017-02-20 00:00:00

abstract：BACKGROUND:The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathophysiological processes and the currently available biological tools for ...

journal_title：Clinical and translational allergy

authors： van Bilsen JHM,Sienkiewicz-Szłapka E,Lozano-Ojalvo D,Willemsen LEM,Antunes CM,Molina E,Smit JJ,Wróblewska B,Wichers HJ,Knol EF,Ladics GS,Pieters RHH,Denery-Papini S,Vissers YM,Bavaro SL,Larré C,Verhoeckx KCM,Roggen EL

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:Recently we reported the validation of the "Allergy-Control-SCORE© (ACS)" which assesses symptom severity as well as medication use on three dimensions lung, nose and eyes. The aim of this study was to test the validity of the score for eyes and nose. METHODS:One-hundred-twenty-one consenting subjects (age ...

journal_title：Clinical and translational allergy

authors： Häfner D,Reich K,Zschocke I,Lotzin A,Meyer H,Kettner J,Narkus A

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The aim of this study was to investigate Health Related Quality of Life (HRQL) in children with and withou...

journal_title：Clinical and translational allergy

authors： Strinnholm Å,Hedman L,Winberg A,Jansson SA,Lindh V,Rönmark E

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:A drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T cell mediated hypersensitivity reaction. Relapses of symptoms in the recovery phase are frequent and linked to the reduction of the corticosteroid treatment, to viral reactivations or to the exposure to new drugs. Here, we analyzed...

journal_title：Clinical and translational allergy

authors： Jörg L,Helbling A,Yerly D,Pichler WJ

更新日期：2020-11-23 00:00:00

abstract：Background:Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and erythema multiforme (EM) are immunologically-mediated dermatological disorders commonly triggered by drug exposure and/or other external agents. We aimed to characterise SJS/TEN- and EM-drug-related hospitalisations in a nationwide administrat...

journal_title：Clinical and translational allergy

authors： Sousa-Pinto B,Araújo L,Freitas A,Correia O,Delgado L

更新日期：2018-01-22 00:00:00

abstract：Background:Blood eosinophil count (BEC) and fractional exhaled nitric oxide (FeNO) concentration are established biomarkers in asthma, associated particularly with the risk of exacerbations. We evaluated the relationship of BEC and FeNO as complementary and independent biomarkers of severe asthma exacerbations. Method...

journal_title：Clinical and translational allergy

authors： Price DB,Bosnic-Anticevich S,Pavord ID,Roche N,Halpin DMG,Bjermer L,Usmani OS,Brusselle G,Ming SWY,Rastogi S

更新日期：2019-08-21 00:00:00

abstract：BACKGROUND:Asthma is a frequent chronic respiratory disease in both children and adults. However, few data on asthma prevalence are available in Portugal. The Portuguese National Asthma Survey is the first nationwide study that uses standardized methods. We aimed to estimate the prevalence of current asthma in the Port...

journal_title：Clinical and translational allergy

authors： Sa-Sousa A,Morais-Almeida M,Azevedo LF,Carvalho R,Jacinto T,Todo-Bom A,Loureiro C,Bugalho-Almeida A,Bousquet J,Fonseca JA

更新日期：2012-08-29 00:00:00

abstract：Background:The relationship between smoking, household pollution, dual exposure and severity of asthma in adults has not been sufficiently studied. We examined and compared the effects of cigarette smoking, domestic wood burning pollution and dual exposure (tobacco and wood burning) upon asthma severity in adults. Met...

journal_title：Clinical and translational allergy

authors： Fernandes AGO,de Souza-Machado C,Pinheiro GP,de Oliva ST,Mota RCL,de Lima VB,Cruz CS,Chatkin JM,Cruz ÁA

更新日期：2018-12-10 00:00:00

abstract：BACKGROUND:With the aim of actively contributing to the ongoing 11(th) International Classification of Diseases (ICD) revision, an international collaboration led by the European Academy of Allergy and Clinical Immunology (EAACI) has decided to revise the classification of hypersensitivity/allergic diseases and to vali...

journal_title：Clinical and translational allergy

authors： Tanno LK,Calderon M,Papadopoulos NG,Demoly P,EAACI\/WAO Task force of a Global Classification of Hypersensitivity\/Allergic diseases.

更新日期：2015-06-03 00:00:00

abstract：:On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European Parliament of Brussels and was hosted by MEP David Borrelli and MEP Sirpa ...

journal_title：Clinical and translational allergy

authors： Hellings PW,Borrelli D,Pietikainen S,Agache I,Akdis C,Bachert C,Bewick M,Botjes E,Constantinidis J,Fokkens W,Haahtela T,Hopkins C,Illario M,Joos G,Lund V,Muraro A,Pugin B,Seys S,Somekh D,Stjärne P,Valiulis A,Val

更新日期：2017-12-27 00:00:00

abstract：BACKGROUND:Indoleamine 2,3-dioxygenase (IDO) is a tryptophan catalyzing enzyme. It has been suggested that it has a role in lower airway allergic inflammations, but its role in allergic rhinitis has not been investigated. OBJECTIVE:Our aim was to evaluate the expression of IDO in the nasal mucosa of allergic rhinitis ...

journal_title：Clinical and translational allergy

authors： Luukkainen A,Karjalainen J,Honkanen T,Lehtonen M,Paavonen T,Toppila-Salmi S

更新日期：2011-12-12 00:00:00

abstract：Background:Pollen is a major cause of allergic respiratory diseases. In Qatar, data on the presence and prevalence of allergenic airborne types of pollen is quite limited. Methods:The study aimed to determine and correlate the most frequently implicated airborne pollen detected by aerobiological monitoring samplers in...

journal_title：Clinical and translational allergy

authors： Al-Nesf MA,Gharbi D,Mobayed HM,Dason BR,Mohammed Ali R,Taha S,Tuffaha A,Adeli M,Sattar HA,Trigo MDM

更新日期：2020-08-10 00:00:00

abstract：Background:Vitamin D has been reported to be associated with many allergic diseases. There are a limited number of the studies of vitamin D supplementation in patients with chronic spontaneous urticaria (CSU). This study aims to study the relationship between vitamin D and CSU in terms of serum vitamin D levels, and th...

journal_title：Clinical and translational allergy

authors： Tuchinda P,Kulthanan K,Chularojanamontri L,Arunkajohnsak S,Sriussadaporn S

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. METHODS:We w...

journal_title：Clinical and translational allergy

authors： Dhami S,Nurmatov U,Pajno GB,Fernandez-Rivas M,Muraro A,Roberts G,Akdis C,Alvaro-Lozano M,Beyer K,Bindslev-Jensen C,Burks W,du Toit G,Ebisawa M,Eigenmann P,Knol E,Makela M,Nadeau KC,O'Mahony L,Papadopoulos N,Poulsen

更新日期：2016-07-05 00:00:00

abstract：BACKGROUND:Little is known about prevalence and risk factors of allergic rhinitis and chronic nasal symptoms among adults in Vietnam. We aimed to estimate the prevalence, risk factor patterns and co-morbidities of allergic rhinitis and chronic nasal symptoms in one urban and one rural area in northern Vietnam. METHODS...

journal_title：Clinical and translational allergy

authors： Lâm HT,Văn T Tng N,Ekerljung L,Rönmark E,Lundbäck B

更新日期：2011-08-11 00:00:00

abstract：Background:Evidence for distinct asthma phenotypes and their overlap is becoming increasingly relevant to identify personalized and targeted therapeutic strategies. In this study, we aimed to describe the overlap of five commonly reported asthma phenotypes in US adults with current asthma and assess its association wit...

journal_title：Clinical and translational allergy

authors： Amaral R,Fonseca JA,Jacinto T,Pereira AM,Malinovschi A,Janson C,Alving K

更新日期：2018-05-04 00:00:00

abstract：BACKGROUND:The efficacy of Lactobacillus paracasei NCC 2461 in modulating allergic rhinitis was previously evaluated in two exploratory clinical studies. Oral administration with NCC 2461 reduced specific subjective symptoms following nasal provocation tests with controlled grass pollen allergen concentrations. Our aim...

journal_title：Clinical and translational allergy

authors： Nembrini C,Singh A,De Castro CA,Mercenier A,Nutten S

更新日期：2015-12-09 00:00:00