Cosmetics for neonates and infants: haptens in products' composition.

abstract：Background:Fungal and bacterial microbiota play an important role in development of asthma. We aim to characterize airway microbiome (mycobiome, bacteriome) and functional genes in asthmatics and controls. Methods:Sputum microbiome of controls, untreated asthma patients and inhaled corticosteroid (ICS) receiving patie...

journal_title：Clinical and translational allergy

authors： Huang C,Yu Y,Du W,Liu Y,Dai R,Tang W,Wang P,Zhang C,Shi G

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:Little is known about prevalence and risk factors of allergic rhinitis and chronic nasal symptoms among adults in Vietnam. We aimed to estimate the prevalence, risk factor patterns and co-morbidities of allergic rhinitis and chronic nasal symptoms in one urban and one rural area in northern Vietnam. METHODS...

journal_title：Clinical and translational allergy

authors： Lâm HT,Văn T Tng N,Ekerljung L,Rönmark E,Lundbäck B

更新日期：2011-08-11 00:00:00

abstract：Background:Asthma with atopy is often characterized by type 2 inflammation but less progress has been made in defining non-type 2 asthma. We have previously identified a subgroup of young non-atopic asthmatics with perceived food hypersensitivity and poor asthma control. Objective:Our aim was to further characterize t...

journal_title：Clinical and translational allergy

authors： Tsolakis N,Nordvall L,Janson C,Rydell N,Malinovschi A,Alving K

更新日期：2019-02-22 00:00:00

abstract：Background:In severe asthma, high doses of inhaled corticosteroids (ICS) are used in order to achieve clinical and functional control. This study aimed to evaluate lung function in outpatients (children and adolescents) with severe asthma in Brazil, all of whom were treated with high doses of ICS. We evaluated all spir...

journal_title：Clinical and translational allergy

authors： Versiani Nunes Pinheiro de Queiroz M,Gonçalves Alvim C,Cruz ÁA,de Lima Belizário Facury Lasmar LM

更新日期：2017-12-15 00:00:00

abstract：Background:Evidence regarding the clinical effectiveness of mite allergen avoidance for the treatment of asthma is lacking. In previous meta-analyses on mite allergen control, the baseline data were not discussed in detail. This study updates and extends the existing Cochrane review by Gøtzsche and Johansen (Cochrane D...

journal_title：Clinical and translational allergy

authors： van Boven FE,de Jong NW,Braunstahl GJ,Gerth van Wijk R,Arends LR

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Asthma is a frequent chronic respiratory disease in both children and adults. However, few data on asthma prevalence are available in Portugal. The Portuguese National Asthma Survey is the first nationwide study that uses standardized methods. We aimed to estimate the prevalence of current asthma in the Port...

journal_title：Clinical and translational allergy

authors： Sa-Sousa A,Morais-Almeida M,Azevedo LF,Carvalho R,Jacinto T,Todo-Bom A,Loureiro C,Bugalho-Almeida A,Bousquet J,Fonseca JA

更新日期：2012-08-29 00:00:00

abstract：BACKGROUND:Although efforts to improve the classification of hypersensitivity/allergic diseases have been made, they have not been considered a top-level category in the International Classification of Diseases (ICD)-10 and still are not in the ICD-11 beta phase linearization. ICD-10 is the most used classification sys...

journal_title：Clinical and translational allergy

authors： Tanno LK,Calderon MA,Goldberg BJ,Akdis CA,Papadopoulos NG,Demoly P

更新日期：2014-11-28 00:00:00

abstract：:Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30% of the total population, hence being associated with an important socio-economic burden. Different phenotypes of rhinitis and CRS...

journal_title：Clinical and translational allergy

authors： De Greve G,Hellings PW,Fokkens WJ,Pugin B,Steelant B,Seys SF

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:The efficacy of Lactobacillus paracasei NCC 2461 in modulating allergic rhinitis was previously evaluated in two exploratory clinical studies. Oral administration with NCC 2461 reduced specific subjective symptoms following nasal provocation tests with controlled grass pollen allergen concentrations. Our aim...

journal_title：Clinical and translational allergy

authors： Nembrini C,Singh A,De Castro CA,Mercenier A,Nutten S

更新日期：2015-12-09 00:00:00

abstract：:[This corrects the article DOI: 10.1186/s13601-016-0116-9.]. ...

journal_title：Clinical and translational allergy

authors： Bousquet J,Farrell J,Crooks G,Hellings P,Bel EH,Bewick M,Chavannes NH,de Sousa JC,Cruz AA,Haahtela T,Joos G,Khaltaev N,Malva J,Muraro A,Nogues M,Palkonen S,Pedersen S,Robalo-Cordeiro C,Samolinski B,Strandberg T,Va

更新日期：2017-02-20 00:00:00

abstract：:Oral allergy syndrome (OAS) is one of the most common IgE-mediated allergic reactions. It is characterized by a number of symptoms induced by the exposure of the oral and pharyngeal mucosa to allergenic proteins belonging to class 1 or to class 2 food allergens. OAS occurring when patients sensitized to pollens are ex...

journal_title：Clinical and translational allergy

authors： Alessandri C,Ferrara R,Bernardi ML,Zennaro D,Tuppo L,Giangrieco I,Ricciardi T,Tamburrini M,Ciardiello MA,Mari A

更新日期：2020-06-17 00:00:00

abstract：:We present three cases with anaphylaxis after injection of a depot corticosteroid. First, the steroid was suspected as the elicitor, but after evaluation the excipient macrogol was found to be the elicitor. One of the patients had reactions to several unrelated drugs. Increased awareness of anaphylaxis to excipients s...

journal_title：Clinical and translational allergy

authors： Brandt N,Garvey LH,Bindslev-Jensen U,Kjaer HF,Bindslev-Jensen C,Mortz CG

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Suspected penicillin allergy (Pen-A) is often not verified by diagnostic testing. In third line penicillin allergy labels were associated with prescription of broad spectrum antibiotics, hospital stay duration and readmission. OBJECTIVE:Assess the impact of Pen-A labels on antibiotic and health care use in ...

journal_title：Clinical and translational allergy

authors： Su T,Broekhuizen BDL,Verheij TJM,Rockmann H

更新日期：2017-06-07 00:00:00

abstract：:Drug hypersensitivity reactions (DHR) have been present since the advent of drugs. In particular T-cell mediated delayed-type hypersensitivity reactions represent a heterogeneous clinical entity with a diverse pathogenesis and result in a considerable burden of morbidity and mortality not only driven by the reactions ...

journal_title：Clinical and translational allergy

authors： Schrijvers R,Gilissen L,Chiriac AM,Demoly P

更新日期：2015-09-03 00:00:00

abstract：Background:Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and erythema multiforme (EM) are immunologically-mediated dermatological disorders commonly triggered by drug exposure and/or other external agents. We aimed to characterise SJS/TEN- and EM-drug-related hospitalisations in a nationwide administrat...

journal_title：Clinical and translational allergy

authors： Sousa-Pinto B,Araújo L,Freitas A,Correia O,Delgado L

更新日期：2018-01-22 00:00:00

abstract：BACKGROUND:The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathophysiological processes and the currently available biological tools for ...

journal_title：Clinical and translational allergy

authors： van Bilsen JHM,Sienkiewicz-Szłapka E,Lozano-Ojalvo D,Willemsen LEM,Antunes CM,Molina E,Smit JJ,Wróblewska B,Wichers HJ,Knol EF,Ladics GS,Pieters RHH,Denery-Papini S,Vissers YM,Bavaro SL,Larré C,Verhoeckx KCM,Roggen EL

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:The European Academy of Allergy and Clinical Immunology is developing guidelines about how to prevent and manage food allergy. As part of the guidelines development process, a systematic review is planned to examine published research about the prevention of food allergy. This systematic review is one of sev...

journal_title：Clinical and translational allergy

authors： de Silva D,Panesar SS,Thusu S,Rader T,Halken S,Muraro A,Sheikh A

更新日期：2013-03-28 00:00:00

abstract：BACKGROUND:The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. METHODS:We w...

journal_title：Clinical and translational allergy

authors： Dhami S,Nurmatov U,Pajno GB,Fernandez-Rivas M,Muraro A,Roberts G,Akdis C,Alvaro-Lozano M,Beyer K,Bindslev-Jensen C,Burks W,du Toit G,Ebisawa M,Eigenmann P,Knol E,Makela M,Nadeau KC,O'Mahony L,Papadopoulos N,Poulsen

更新日期：2016-07-05 00:00:00

abstract：BACKGROUND:Double-blind, placebo-controlled (DBPC) trials are the gold standard for demonstrating clinical efficacy and tolerability. The placebo effect, although an important feature in placebo-controlled studies, has never been systematically investigated in allergen-specific immunotherapy (SIT) studies. This study w...

journal_title：Clinical and translational allergy

authors： Narkus A,Lehnigk U,Haefner D,Klinger R,Pfaar O,Worm M

更新日期：2013-12-21 00:00:00

abstract：:Crying combined with miscellaneous gastrointestinal symptoms are typical symptoms of infant with food allergy, but are also common among children with abnormal neurological development. Mutations in KAT6A gene is known to cause a syndrome characterized by developmental delay, hypotonia, cardiac defects, microcephaly, ...

journal_title：Clinical and translational allergy

authors： Elenius V,Lähdesmäki T,Hietala M,Jartti T

更新日期：2017-06-22 00:00:00

abstract：Background:Diagnostic workup of penicillin allergy comprises skin testing with penicillins, and patients are deemed allergic if skin test is positive. However, the literature suggests that skin test-positive patients may be challenge-negative, indicating that the skin test may be falsely positive. Objective:To investi...

journal_title：Clinical and translational allergy

authors： Tannert LK,Falkencrone S,Mortz CG,Bindslev-Jensen C,Skov PS

更新日期：2017-11-17 00:00:00

abstract：BACKGROUND:While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The aim of this study was to investigate Health Related Quality of Life (HRQL) in children with and withou...

journal_title：Clinical and translational allergy

authors： Strinnholm Å,Hedman L,Winberg A,Jansson SA,Lindh V,Rönmark E

更新日期：2017-07-03 00:00:00

abstract：Background:In daily practice, one-third of sesame allergic patients, confirmed by clinical history or food challenge, do not show any detectable specific IgE using current diagnostics. Currently used sesame extracts are water-based and therefore lacking hydrophobic proteins like oleosins. Oleosins, the stabilizer of li...

journal_title：Clinical and translational allergy

authors： Ehlers AM,Rossnagel M,Brix B,Blankestijn MA,Le TM,Suer W,Otten HG,Knulst AC

更新日期：2019-06-28 00:00:00

abstract：Background:The relationship between smoking, household pollution, dual exposure and severity of asthma in adults has not been sufficiently studied. We examined and compared the effects of cigarette smoking, domestic wood burning pollution and dual exposure (tobacco and wood burning) upon asthma severity in adults. Met...

journal_title：Clinical and translational allergy

authors： Fernandes AGO,de Souza-Machado C,Pinheiro GP,de Oliva ST,Mota RCL,de Lima VB,Cruz CS,Chatkin JM,Cruz ÁA

更新日期：2018-12-10 00:00:00

abstract：Background:Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease usually characterized by chronic eosinophilia in the sinonasal mucosa, which often requires glucocorticoid (GC) therapy. However, the therapeutic response varies markedly between individuals. The objective of this study...

journal_title：Clinical and translational allergy

authors： Hong H,Wang D,Tan KS,Zheng R,Chen F,Gao W,He H,Shi J,Fan Y,Yang Q,Sun Y

更新日期：2018-07-02 00:00:00

abstract：BACKGROUND:A drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T cell mediated hypersensitivity reaction. Relapses of symptoms in the recovery phase are frequent and linked to the reduction of the corticosteroid treatment, to viral reactivations or to the exposure to new drugs. Here, we analyzed...

journal_title：Clinical and translational allergy

authors： Jörg L,Helbling A,Yerly D,Pichler WJ

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Cow's milk allergy (CMA) is a common disease in infancy. Early environmental factors are likely to contribute to CMA. It is known that epigenetic gene regulation can be altered by environmental factors. We have set up a proof of concept study, aiming to detect epigenetic associations specific with CMA. METH...

journal_title：Clinical and translational allergy

authors： Petrus NCM,Henneman P,Venema A,Mul A,van Sinderen F,Haagmans M,Mook O,Hennekam RC,Sprikkelman AB,Mannens M

更新日期：2016-05-04 00:00:00

abstract：BACKGROUND:The 300IR (index of reactivity) 5-grass pollen tablet has favorable short-term and sustained clinical efficacy in patients with grass pollen-induced allergic rhinoconjunctivitis (ARC). Here, we report maintenance of efficacy and safety over 2 years following treatment discontinuation. METHODS:Randomized, do...

journal_title：Clinical and translational allergy

authors： Didier A,Malling HJ,Worm M,Horak F,Sussman GL

更新日期：2015-05-22 00:00:00

abstract：BACKGROUND:With the aim of actively contributing to the ongoing 11(th) International Classification of Diseases (ICD) revision, an international collaboration led by the European Academy of Allergy and Clinical Immunology (EAACI) has decided to revise the classification of hypersensitivity/allergic diseases and to vali...

journal_title：Clinical and translational allergy

authors： Tanno LK,Calderon M,Papadopoulos NG,Demoly P,EAACI\/WAO Task force of a Global Classification of Hypersensitivity\/Allergic diseases.

更新日期：2015-06-03 00:00:00

abstract：BACKGROUND:For the development of forecasts for seasonal allergic rhinitis symptoms, it is essential to understand the relationship between grass pollen concentrations and the symptoms of grass pollen allergic patients. OBJECTIVE:The aim of this study was to delineate this relationship between seasonal allergic rhinit...

journal_title：Clinical and translational allergy

authors： de Weger LA,Beerthuizen T,Gast-Strookman JM,van der Plas DT,Terreehorst I,Hiemstra PS,Sont JK

更新日期：2011-12-21 00:00:00