Abstract:
BACKGROUND:While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The aim of this study was to investigate Health Related Quality of Life (HRQL) in children with and without food hypersensitivity. Further, we compared HRQL between children with different phenotypes of food hypersensitivity. METHODS:In a large population-based cohort of schoolchildren in Northern Sweden, the parents of 2612 (96% of invited) completed a questionnaire. All 125 (5%) children who reported complete elimination of milk, egg, fish or wheat due to food hypersensitivity were invited to a clinical examination and 94 children participated. Of these, 75 children also completed a generic (KIDSCREEN-52) and a disease-specific HRQL questionnaire (FAQLQ-TF). Thereafter, these children were categorised into the different phenotypes: current food allergy, outgrown food allergy, and lactose intolerance. Additionally, 209 children with unrestricted diets answered the generic questionnaire. RESULTS:The median score of all KIDSCREEN-52 domains were above the population norm of 50 both in children with and without food hypersensitivity. No significant differences in distribution in generic or disease-specific HRQL were found between children with or without food hypersensitivity. There were no significant differences in HRQL between children with different phenotypes of food hypersensitivity. However, children with current food allergy tended to have the lowest HRQL. Further, poor HRQL defined as ≥75th percentile for the disease specific score was significantly more common in the current food allergy phenotype in the domain Emotional impact and the total FAQLQ, compared to the other phenotypes. CONCLUSIONS:In this population-based study, 12-13 year old children reported good HRQL regardless of having food hypersensitivity or not. However, the children with the current phenotype reported lower HRQL than the other phenotypes.
journal_name
Clin Transl Allergyjournal_title
Clinical and translational allergyauthors
Strinnholm Å,Hedman L,Winberg A,Jansson SA,Lindh V,Rönmark Edoi
10.1186/s13601-017-0156-9subject
Has Abstractpub_date
2017-07-03 00:00:00pages
20issn
2045-7022pii
156journal_volume
7pub_type
杂志文章abstract:BACKGROUND:Although efforts to improve the classification of hypersensitivity/allergic diseases have been made, they have not been considered a top-level category in the International Classification of Diseases (ICD)-10 and still are not in the ICD-11 beta phase linearization. ICD-10 is the most used classification sys...
journal_title:Clinical and translational allergy
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
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journal_title:Clinical and translational allergy
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journal_title:Clinical and translational allergy
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1186/2045-7022-3-10
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/2045-7022-1-17
更新日期:2011-12-12 00:00:00
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journal_title:Clinical and translational allergy
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journal_title:Clinical and translational allergy
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doi:10.1186/s13601-015-0085-4
更新日期:2015-12-09 00:00:00
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pub_type: 杂志文章
doi:10.1186/s13601-017-0155-x
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/2045-7022-2-15
更新日期:2012-08-29 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章,评审
doi:10.1186/s13601-017-0157-8
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更新日期:2011-12-21 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-018-0234-7
更新日期:2018-12-04 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
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更新日期:2018-07-02 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
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更新日期:2015-06-03 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/2045-7022-1-7
更新日期:2011-08-11 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章,评审
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更新日期:2015-09-03 00:00:00
abstract::[This corrects the article DOI: 10.1186/s13601-019-0303-6.]. ...
journal_title:Clinical and translational allergy
pub_type: 已发布勘误
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更新日期:2020-09-28 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
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更新日期:2020-11-23 00:00:00
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journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-019-0282-7
更新日期:2019-08-21 00:00:00