Abstract:
BACKGROUND:Little is known about prevalence and risk factors of allergic rhinitis and chronic nasal symptoms among adults in Vietnam. We aimed to estimate the prevalence, risk factor patterns and co-morbidities of allergic rhinitis and chronic nasal symptoms in one urban and one rural area in northern Vietnam. METHODS:A cross-sectional questionnaire survey was conducted from August 2007 to January 2008 in urban Hoankiem and rural Bavi in Hanoi among adults aged 21-70 years. Of 7008 randomly selected subjects, 91.7% participated in Bavi and 70.3% in Hoankiem. RESULTS:Allergic rhinitis ever or chronic nasal symptoms were reported by 50.2%. The prevalence of allergic rhinitis ever was considerably higher in Hoankiem compared to Bavi, 29.6% vs 10.0% (p < 0.001). Allergic rhinitis ever and chronic nasal symptoms were both significantly associated with asthma and respiratory symptoms, respectively (p < 0.001). Exposure to gas, dust or fumes at work was significantly associated with allergic rhinitis ever, OR 1.57 (95% CI 1.34 - 1.84), nasal blocking, OR 1.90 (95% CI 1.68 - 2.15) and runny nose, OR 1.32 (95% CI 1.17 - 1.49), while somewhat surprisingly no association with smoking was found. Female sex was a significant risk factor for both nasal blocking and runny nose. CONCLUSIONS:Allergic rhinitis ever was considerably more common in the urban area. Nasal blocking and runny nose was each reported by about one third of the studied sample with no major urban-rural difference. Further, exposure to air pollution at work was significantly associated with allergic rhinitis ever, nasal blocking and runny nose.
journal_name
Clin Transl Allergyjournal_title
Clinical and translational allergyauthors
Lâm HT,Văn T Tng N,Ekerljung L,Rönmark E,Lundbäck Bdoi
10.1186/2045-7022-1-7subject
Has Abstractpub_date
2011-08-11 00:00:00pages
7issue
1issn
2045-7022pii
2045-7022-1-7journal_volume
1pub_type
杂志文章abstract:Background:Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and erythema multiforme (EM) are immunologically-mediated dermatological disorders commonly triggered by drug exposure and/or other external agents. We aimed to characterise SJS/TEN- and EM-drug-related hospitalisations in a nationwide administrat...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-017-0188-1
更新日期:2018-01-22 00:00:00
abstract::Crying combined with miscellaneous gastrointestinal symptoms are typical symptoms of infant with food allergy, but are also common among children with abnormal neurological development. Mutations in KAT6A gene is known to cause a syndrome characterized by developmental delay, hypotonia, cardiac defects, microcephaly, ...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-017-0155-x
更新日期:2017-06-22 00:00:00
abstract:Background:In severe asthma, high doses of inhaled corticosteroids (ICS) are used in order to achieve clinical and functional control. This study aimed to evaluate lung function in outpatients (children and adolescents) with severe asthma in Brazil, all of whom were treated with high doses of ICS. We evaluated all spir...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-017-0183-6
更新日期:2017-12-15 00:00:00
abstract:Background:Rhinitis is a common problem within the population. Many subjects with rhinitis also have atopic multimorbidity, such as asthma and eczema. The purpose of this investigation was to compare subjects with only rhinitis to those that have rhinitis, asthma and/or eczema in relation to immunoglobulin E (IgE) sens...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-020-0311-6
更新日期:2020-02-21 00:00:00
abstract:BACKGROUND:The FOXP3 gene is the master regulator for T regulatory cells and is under tight DNA methylation control at the Treg specific demethylated region (TSDR) in its first intron. This said, methylation of its promoter region, the significance of which is unknown, has also been associated with various immune-relat...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-015-0079-2
更新日期:2015-10-20 00:00:00
abstract:Background:Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease usually characterized by chronic eosinophilia in the sinonasal mucosa, which often requires glucocorticoid (GC) therapy. However, the therapeutic response varies markedly between individuals. The objective of this study...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-018-0211-1
更新日期:2018-07-02 00:00:00
abstract:Background:Asthma with atopy is often characterized by type 2 inflammation but less progress has been made in defining non-type 2 asthma. We have previously identified a subgroup of young non-atopic asthmatics with perceived food hypersensitivity and poor asthma control. Objective:Our aim was to further characterize t...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-019-0250-2
更新日期:2019-02-22 00:00:00
abstract::Eosinophilic disorders represent a group of pathologic conditions with highly heterogeneous pathophysiology and clinical presentation and variable prognosis, ranging from asymptomatic or mild, to severe and complex cases, with fatal outcome. Interest in this group of disorders has increased during the last two decades...
journal_title:Clinical and translational allergy
pub_type: 杂志文章,评审
doi:10.1186/s13601-019-0277-4
更新日期:2019-07-25 00:00:00
abstract:BACKGROUND:While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The aim of this study was to investigate Health Related Quality of Life (HRQL) in children with and withou...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-017-0156-9
更新日期:2017-07-03 00:00:00
abstract::Drug hypersensitivity reactions (DHR) have been present since the advent of drugs. In particular T-cell mediated delayed-type hypersensitivity reactions represent a heterogeneous clinical entity with a diverse pathogenesis and result in a considerable burden of morbidity and mortality not only driven by the reactions ...
journal_title:Clinical and translational allergy
pub_type: 杂志文章,评审
doi:10.1186/s13601-015-0073-8
更新日期:2015-09-03 00:00:00
abstract:BACKGROUND:Although efforts to improve the classification of hypersensitivity/allergic diseases have been made, they have not been considered a top-level category in the International Classification of Diseases (ICD)-10 and still are not in the ICD-11 beta phase linearization. ICD-10 is the most used classification sys...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/2045-7022-4-42
更新日期:2014-11-28 00:00:00
abstract::Cosmetics and skin care products for neonates and infants are considered as ''hypoallergenic'', "tested" or ''safe''. Nevertheless, the prevalence of haptens in these products is a matter of concern, since allergic contact dermatitis in children is gaining an importance. We aimed to assess the prevalence of haptens in...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-019-0257-8
更新日期:2019-03-08 00:00:00
abstract:BACKGROUND:Asthma is a frequent chronic respiratory disease in both children and adults. However, few data on asthma prevalence are available in Portugal. The Portuguese National Asthma Survey is the first nationwide study that uses standardized methods. We aimed to estimate the prevalence of current asthma in the Port...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/2045-7022-2-15
更新日期:2012-08-29 00:00:00
abstract::[This corrects the article DOI: 10.1186/s13601-019-0303-6.]. ...
journal_title:Clinical and translational allergy
pub_type: 已发布勘误
doi:10.1186/s13601-020-00343-w
更新日期:2020-09-28 00:00:00
abstract:BACKGROUND:Recently we reported the validation of the "Allergy-Control-SCORE© (ACS)" which assesses symptom severity as well as medication use on three dimensions lung, nose and eyes. The aim of this study was to test the validity of the score for eyes and nose. METHODS:One-hundred-twenty-one consenting subjects (age ...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/2045-7022-2-17
更新日期:2012-09-19 00:00:00
abstract:BACKGROUND:Suspected penicillin allergy (Pen-A) is often not verified by diagnostic testing. In third line penicillin allergy labels were associated with prescription of broad spectrum antibiotics, hospital stay duration and readmission. OBJECTIVE:Assess the impact of Pen-A labels on antibiotic and health care use in ...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-017-0154-y
更新日期:2017-06-07 00:00:00
abstract:Background:Blood eosinophil count (BEC) and fractional exhaled nitric oxide (FeNO) concentration are established biomarkers in asthma, associated particularly with the risk of exacerbations. We evaluated the relationship of BEC and FeNO as complementary and independent biomarkers of severe asthma exacerbations. Method...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-019-0282-7
更新日期:2019-08-21 00:00:00
abstract:BACKGROUND:Cow's milk allergy (CMA) is a common disease in infancy. Early environmental factors are likely to contribute to CMA. It is known that epigenetic gene regulation can be altered by environmental factors. We have set up a proof of concept study, aiming to detect epigenetic associations specific with CMA. METH...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-016-0105-z
更新日期:2016-05-04 00:00:00
abstract:Background:The relationship between smoking, household pollution, dual exposure and severity of asthma in adults has not been sufficiently studied. We examined and compared the effects of cigarette smoking, domestic wood burning pollution and dual exposure (tobacco and wood burning) upon asthma severity in adults. Met...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-018-0235-6
更新日期:2018-12-10 00:00:00
abstract::On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European Parliament of Brussels and was hosted by MEP David Borrelli and MEP Sirpa ...
journal_title:Clinical and translational allergy
pub_type: 杂志文章,评审
doi:10.1186/s13601-017-0186-3
更新日期:2017-12-27 00:00:00
abstract:Background:Evidence regarding the clinical effectiveness of mite allergen avoidance for the treatment of asthma is lacking. In previous meta-analyses on mite allergen control, the baseline data were not discussed in detail. This study updates and extends the existing Cochrane review by Gøtzsche and Johansen (Cochrane D...
journal_title:Clinical and translational allergy
pub_type: 杂志文章,评审
doi:10.1186/s13601-019-0306-3
更新日期:2020-01-06 00:00:00
abstract:Background:Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and comorbid asthma have more severe disease and are difficult to treat. However, the molecular endotypes associated with CRSwNP with comorbid asthma (CRSwNP + AS) are not clear. This study aimed to investigate the characteristics of type 2 infl...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-020-00332-z
更新日期:2020-07-03 00:00:00
abstract:BACKGROUND:The 300IR (index of reactivity) 5-grass pollen tablet has favorable short-term and sustained clinical efficacy in patients with grass pollen-induced allergic rhinoconjunctivitis (ARC). Here, we report maintenance of efficacy and safety over 2 years following treatment discontinuation. METHODS:Randomized, do...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-015-0057-8
更新日期:2015-05-22 00:00:00
abstract:Background:Pollen is a major cause of allergic respiratory diseases. In Qatar, data on the presence and prevalence of allergenic airborne types of pollen is quite limited. Methods:The study aimed to determine and correlate the most frequently implicated airborne pollen detected by aerobiological monitoring samplers in...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-020-00339-6
更新日期:2020-08-10 00:00:00
abstract:Background:Diagnostic workup of penicillin allergy comprises skin testing with penicillins, and patients are deemed allergic if skin test is positive. However, the literature suggests that skin test-positive patients may be challenge-negative, indicating that the skin test may be falsely positive. Objective:To investi...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-017-0179-2
更新日期:2017-11-17 00:00:00
abstract::Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30% of the total population, hence being associated with an important socio-economic burden. Different phenotypes of rhinitis and CRS...
journal_title:Clinical and translational allergy
pub_type: 杂志文章,评审
doi:10.1186/s13601-017-0157-8
更新日期:2017-07-12 00:00:00
abstract:BACKGROUND:A drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T cell mediated hypersensitivity reaction. Relapses of symptoms in the recovery phase are frequent and linked to the reduction of the corticosteroid treatment, to viral reactivations or to the exposure to new drugs. Here, we analyzed...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-020-00359-2
更新日期:2020-11-23 00:00:00
abstract:BACKGROUND:Subcutaneous immunotherapy with high dose grass pollen (typically microgram quantities) was first described over 100 years ago. This treatment suppresses allergen-induced cutaneous late responses, with lesser effects on early responses. We previously reported that repeated 2-weekly intradermal injections of ...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/2045-7022-3-27
更新日期:2013-08-21 00:00:00
abstract::[This corrects the article DOI: 10.1186/s13601-016-0116-9.]. ...
journal_title:Clinical and translational allergy
pub_type: 已发布勘误
doi:10.1186/s13601-016-0135-6
更新日期:2017-02-20 00:00:00
abstract:Background:Fungal and bacterial microbiota play an important role in development of asthma. We aim to characterize airway microbiome (mycobiome, bacteriome) and functional genes in asthmatics and controls. Methods:Sputum microbiome of controls, untreated asthma patients and inhaled corticosteroid (ICS) receiving patie...
journal_title:Clinical and translational allergy
pub_type: 杂志文章
doi:10.1186/s13601-020-00345-8
更新日期:2020-10-22 00:00:00