A meta-analysis of baseline characteristics in trials on mite allergen avoidance in asthmatics: room for improvement.

abstract：Background:The relationship between smoking, household pollution, dual exposure and severity of asthma in adults has not been sufficiently studied. We examined and compared the effects of cigarette smoking, domestic wood burning pollution and dual exposure (tobacco and wood burning) upon asthma severity in adults. Met...

journal_title：Clinical and translational allergy

authors： Fernandes AGO,de Souza-Machado C,Pinheiro GP,de Oliva ST,Mota RCL,de Lima VB,Cruz CS,Chatkin JM,Cruz ÁA

更新日期：2018-12-10 00:00:00

abstract：:On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European Parliament of Brussels and was hosted by MEP David Borrelli and MEP Sirpa ...

journal_title：Clinical and translational allergy

authors： Hellings PW,Borrelli D,Pietikainen S,Agache I,Akdis C,Bachert C,Bewick M,Botjes E,Constantinidis J,Fokkens W,Haahtela T,Hopkins C,Illario M,Joos G,Lund V,Muraro A,Pugin B,Seys S,Somekh D,Stjärne P,Valiulis A,Val

更新日期：2017-12-27 00:00:00

abstract：UNLABELLED: BACKGROUND:The transition to adulthood can be particularly challenging for young people with severe allergies, who must learn to balance personal safety with independent living. Information and support for young people and their families are crucial to successfully managing this transition. We sought to: g...

journal_title：Clinical and translational allergy

authors： Worth A,Regent L,Levy M,Ledford C,East M,Sheikh A

更新日期：2013-01-22 00:00:00

abstract：Background:Asthma with atopy is often characterized by type 2 inflammation but less progress has been made in defining non-type 2 asthma. We have previously identified a subgroup of young non-atopic asthmatics with perceived food hypersensitivity and poor asthma control. Objective:Our aim was to further characterize t...

journal_title：Clinical and translational allergy

authors： Tsolakis N,Nordvall L,Janson C,Rydell N,Malinovschi A,Alving K

更新日期：2019-02-22 00:00:00

abstract：:[This corrects the article DOI: 10.1186/s13601-019-0303-6.]. ...

journal_title：Clinical and translational allergy

authors： Hox V,Lourijsen E,Jordens A,Aasbjerg K,Agache I,Alobid I,Bachert C,Boussery K,Campo P,Fokkens W,Hellings P,Hopkins C,Klimek L,Mäkelä M,Mösges R,Mullol J,Pujols L,Rondon C,Rudenko M,Toppila-Salmi S,Scadding G,Sch

更新日期：2020-09-28 00:00:00

abstract：:[This corrects the article DOI: 10.1186/s13601-016-0116-9.]. ...

journal_title：Clinical and translational allergy

authors： Bousquet J,Farrell J,Crooks G,Hellings P,Bel EH,Bewick M,Chavannes NH,de Sousa JC,Cruz AA,Haahtela T,Joos G,Khaltaev N,Malva J,Muraro A,Nogues M,Palkonen S,Pedersen S,Robalo-Cordeiro C,Samolinski B,Strandberg T,Va

更新日期：2017-02-20 00:00:00

abstract：Background:Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and erythema multiforme (EM) are immunologically-mediated dermatological disorders commonly triggered by drug exposure and/or other external agents. We aimed to characterise SJS/TEN- and EM-drug-related hospitalisations in a nationwide administrat...

journal_title：Clinical and translational allergy

authors： Sousa-Pinto B,Araújo L,Freitas A,Correia O,Delgado L

更新日期：2018-01-22 00:00:00

abstract：Background:Diagnostic workup of penicillin allergy comprises skin testing with penicillins, and patients are deemed allergic if skin test is positive. However, the literature suggests that skin test-positive patients may be challenge-negative, indicating that the skin test may be falsely positive. Objective:To investi...

journal_title：Clinical and translational allergy

authors： Tannert LK,Falkencrone S,Mortz CG,Bindslev-Jensen C,Skov PS

更新日期：2017-11-17 00:00:00

abstract：:Oral allergy syndrome (OAS) is one of the most common IgE-mediated allergic reactions. It is characterized by a number of symptoms induced by the exposure of the oral and pharyngeal mucosa to allergenic proteins belonging to class 1 or to class 2 food allergens. OAS occurring when patients sensitized to pollens are ex...

journal_title：Clinical and translational allergy

authors： Alessandri C,Ferrara R,Bernardi ML,Zennaro D,Tuppo L,Giangrieco I,Ricciardi T,Tamburrini M,Ciardiello MA,Mari A

更新日期：2020-06-17 00:00:00

abstract：:Crying combined with miscellaneous gastrointestinal symptoms are typical symptoms of infant with food allergy, but are also common among children with abnormal neurological development. Mutations in KAT6A gene is known to cause a syndrome characterized by developmental delay, hypotonia, cardiac defects, microcephaly, ...

journal_title：Clinical and translational allergy

authors： Elenius V,Lähdesmäki T,Hietala M,Jartti T

更新日期：2017-06-22 00:00:00

abstract：BACKGROUND:Indoleamine 2,3-dioxygenase (IDO) is a tryptophan catalyzing enzyme. It has been suggested that it has a role in lower airway allergic inflammations, but its role in allergic rhinitis has not been investigated. OBJECTIVE:Our aim was to evaluate the expression of IDO in the nasal mucosa of allergic rhinitis ...

journal_title：Clinical and translational allergy

authors： Luukkainen A,Karjalainen J,Honkanen T,Lehtonen M,Paavonen T,Toppila-Salmi S

更新日期：2011-12-12 00:00:00

abstract：BACKGROUND:Double-blind, placebo-controlled (DBPC) trials are the gold standard for demonstrating clinical efficacy and tolerability. The placebo effect, although an important feature in placebo-controlled studies, has never been systematically investigated in allergen-specific immunotherapy (SIT) studies. This study w...

journal_title：Clinical and translational allergy

authors： Narkus A,Lehnigk U,Haefner D,Klinger R,Pfaar O,Worm M

更新日期：2013-12-21 00:00:00

abstract：:Eosinophilic disorders represent a group of pathologic conditions with highly heterogeneous pathophysiology and clinical presentation and variable prognosis, ranging from asymptomatic or mild, to severe and complex cases, with fatal outcome. Interest in this group of disorders has increased during the last two decades...

journal_title：Clinical and translational allergy

authors： Leru PM

更新日期：2019-07-25 00:00:00

abstract：Background:In severe asthma, high doses of inhaled corticosteroids (ICS) are used in order to achieve clinical and functional control. This study aimed to evaluate lung function in outpatients (children and adolescents) with severe asthma in Brazil, all of whom were treated with high doses of ICS. We evaluated all spir...

journal_title：Clinical and translational allergy

authors： Versiani Nunes Pinheiro de Queiroz M,Gonçalves Alvim C,Cruz ÁA,de Lima Belizário Facury Lasmar LM

更新日期：2017-12-15 00:00:00

abstract：BACKGROUND:Although efforts to improve the classification of hypersensitivity/allergic diseases have been made, they have not been considered a top-level category in the International Classification of Diseases (ICD)-10 and still are not in the ICD-11 beta phase linearization. ICD-10 is the most used classification sys...

journal_title：Clinical and translational allergy

authors： Tanno LK,Calderon MA,Goldberg BJ,Akdis CA,Papadopoulos NG,Demoly P

更新日期：2014-11-28 00:00:00

abstract：Background:Vitamin D has been reported to be associated with many allergic diseases. There are a limited number of the studies of vitamin D supplementation in patients with chronic spontaneous urticaria (CSU). This study aims to study the relationship between vitamin D and CSU in terms of serum vitamin D levels, and th...

journal_title：Clinical and translational allergy

authors： Tuchinda P,Kulthanan K,Chularojanamontri L,Arunkajohnsak S,Sriussadaporn S

更新日期：2018-12-04 00:00:00

abstract：Background:Blood eosinophil count (BEC) and fractional exhaled nitric oxide (FeNO) concentration are established biomarkers in asthma, associated particularly with the risk of exacerbations. We evaluated the relationship of BEC and FeNO as complementary and independent biomarkers of severe asthma exacerbations. Method...

journal_title：Clinical and translational allergy

authors： Price DB,Bosnic-Anticevich S,Pavord ID,Roche N,Halpin DMG,Bjermer L,Usmani OS,Brusselle G,Ming SWY,Rastogi S

更新日期：2019-08-21 00:00:00

abstract：BACKGROUND:The FOXP3 gene is the master regulator for T regulatory cells and is under tight DNA methylation control at the Treg specific demethylated region (TSDR) in its first intron. This said, methylation of its promoter region, the significance of which is unknown, has also been associated with various immune-relat...

journal_title：Clinical and translational allergy

authors： Bégin P,Schulze J,Baron U,Olek S,Bauer RN,Passerini L,Baccheta R,Nadeau KC

更新日期：2015-10-20 00:00:00

abstract：Background:In daily practice, one-third of sesame allergic patients, confirmed by clinical history or food challenge, do not show any detectable specific IgE using current diagnostics. Currently used sesame extracts are water-based and therefore lacking hydrophobic proteins like oleosins. Oleosins, the stabilizer of li...

journal_title：Clinical and translational allergy

authors： Ehlers AM,Rossnagel M,Brix B,Blankestijn MA,Le TM,Suer W,Otten HG,Knulst AC

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:The efficacy of Lactobacillus paracasei NCC 2461 in modulating allergic rhinitis was previously evaluated in two exploratory clinical studies. Oral administration with NCC 2461 reduced specific subjective symptoms following nasal provocation tests with controlled grass pollen allergen concentrations. Our aim...

journal_title：Clinical and translational allergy

authors： Nembrini C,Singh A,De Castro CA,Mercenier A,Nutten S

更新日期：2015-12-09 00:00:00

abstract：BACKGROUND:Little is known about prevalence and risk factors of allergic rhinitis and chronic nasal symptoms among adults in Vietnam. We aimed to estimate the prevalence, risk factor patterns and co-morbidities of allergic rhinitis and chronic nasal symptoms in one urban and one rural area in northern Vietnam. METHODS...

journal_title：Clinical and translational allergy

authors： Lâm HT,Văn T Tng N,Ekerljung L,Rönmark E,Lundbäck B

更新日期：2011-08-11 00:00:00

abstract：:Drug hypersensitivity reactions (DHR) have been present since the advent of drugs. In particular T-cell mediated delayed-type hypersensitivity reactions represent a heterogeneous clinical entity with a diverse pathogenesis and result in a considerable burden of morbidity and mortality not only driven by the reactions ...

journal_title：Clinical and translational allergy

authors： Schrijvers R,Gilissen L,Chiriac AM,Demoly P

更新日期：2015-09-03 00:00:00

abstract：Background:Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and comorbid asthma have more severe disease and are difficult to treat. However, the molecular endotypes associated with CRSwNP with comorbid asthma (CRSwNP + AS) are not clear. This study aimed to investigate the characteristics of type 2 infl...

journal_title：Clinical and translational allergy

authors： Wang M,Bu X,Luan G,Lin L,Wang Y,Jin J,Zhang L,Wang C

更新日期：2020-07-03 00:00:00

abstract：:Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30% of the total population, hence being associated with an important socio-economic burden. Different phenotypes of rhinitis and CRS...

journal_title：Clinical and translational allergy

authors： De Greve G,Hellings PW,Fokkens WJ,Pugin B,Steelant B,Seys SF

更新日期：2017-07-12 00:00:00

abstract：:Cosmetics and skin care products for neonates and infants are considered as ''hypoallergenic'', "tested" or ''safe''. Nevertheless, the prevalence of haptens in these products is a matter of concern, since allergic contact dermatitis in children is gaining an importance. We aimed to assess the prevalence of haptens in...

journal_title：Clinical and translational allergy

authors： Dumycz K,Kunkiel K,Feleszko W

更新日期：2019-03-08 00:00:00

abstract：BACKGROUND:Asthma is a frequent chronic respiratory disease in both children and adults. However, few data on asthma prevalence are available in Portugal. The Portuguese National Asthma Survey is the first nationwide study that uses standardized methods. We aimed to estimate the prevalence of current asthma in the Port...

journal_title：Clinical and translational allergy

authors： Sa-Sousa A,Morais-Almeida M,Azevedo LF,Carvalho R,Jacinto T,Todo-Bom A,Loureiro C,Bugalho-Almeida A,Bousquet J,Fonseca JA

更新日期：2012-08-29 00:00:00

abstract：BACKGROUND:A drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T cell mediated hypersensitivity reaction. Relapses of symptoms in the recovery phase are frequent and linked to the reduction of the corticosteroid treatment, to viral reactivations or to the exposure to new drugs. Here, we analyzed...

journal_title：Clinical and translational allergy

authors： Jörg L,Helbling A,Yerly D,Pichler WJ

更新日期：2020-11-23 00:00:00

abstract：Background:Fungal and bacterial microbiota play an important role in development of asthma. We aim to characterize airway microbiome (mycobiome, bacteriome) and functional genes in asthmatics and controls. Methods:Sputum microbiome of controls, untreated asthma patients and inhaled corticosteroid (ICS) receiving patie...

journal_title：Clinical and translational allergy

authors： Huang C,Yu Y,Du W,Liu Y,Dai R,Tang W,Wang P,Zhang C,Shi G

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:Subcutaneous immunotherapy with high dose grass pollen (typically microgram quantities) was first described over 100 years ago. This treatment suppresses allergen-induced cutaneous late responses, with lesser effects on early responses. We previously reported that repeated 2-weekly intradermal injections of ...

journal_title：Clinical and translational allergy

authors： Slovick A,Douiri A,Kelly J,Guerra A,Muir R,Tsioulos K,Murphy C,Shamji MH,Ying S,Durham SR,Till SJ

更新日期：2013-08-21 00:00:00

abstract：BACKGROUND:With the aim of actively contributing to the ongoing 11(th) International Classification of Diseases (ICD) revision, an international collaboration led by the European Academy of Allergy and Clinical Immunology (EAACI) has decided to revise the classification of hypersensitivity/allergic diseases and to vali...

journal_title：Clinical and translational allergy

authors： Tanno LK,Calderon M,Papadopoulos NG,Demoly P,EAACI\/WAO Task force of a Global Classification of Hypersensitivity\/Allergic diseases.

更新日期：2015-06-03 00:00:00