Using mobile phone text messaging for malaria surveillance in rural Kenya.

abstract：BACKGROUND:The Drugs for Neglected Diseases initiative (DNDi) is a not-for profit organization committed to providing affordable medicines and access to treatments in resource-poor settings. Traditionally drug development has happened "in house" within pharmaceutical companies, with research and development costs ultim...

journal_title：Malaria journal

authors： Wells S,Diap G,Kiechel JR

更新日期：2013-02-21 00:00:00

abstract：BACKGROUND:Previous efforts to eradicate malaria parasites, particularly Plasmodium falciparum, have failed in part due to the emergence of drug resistant parasites and mosquitoes resistant to insecticides. Using an artemisinin-based combination therapy (ACT) that kills parasites quickly, a strategy was designed to eli...

journal_title：Malaria journal

authors： Song J,Socheat D,Tan B,Dara P,Deng C,Sokunthea S,Seila S,Ou F,Jian H,Li G

更新日期：2010-02-23 00:00:00

abstract：BACKGROUND:The adaptation of malaria vectors to urban areas is becoming a serious challenge for malaria control. The study presents the evolution of pyrethroid resistance in mosquito populations from the cities of Douala and Yaoundé between 2010 and 2013. METHODS:Susceptibility tests to permethrin and deltamethrin wer...

journal_title：Malaria journal

authors： Antonio-Nkondjio C,Tene Fossog B,Kopya E,Poumachu Y,Menze Djantio B,Ndo C,Tchuinkam T,Awono-Ambene P,Wondji CS

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:Malaria is a major health problem in sub-Saharan Africa where over 90% of the world's malaria cases occur. Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization as first-line and second-line treatments for uncomplicated falciparum malaria. However, there are a growing nu...

journal_title：Malaria journal

authors： Ndwigah S,Stergachis A,Abuga K,Mugo H,Kibwage I

更新日期：2018-09-15 00:00:00

abstract：BACKGROUND:Primaquine is effective against the latent liver stage of Plasmodium vivax. Eliminating the latent liver stage of P. vivax is one of the necessary conditions to achieve the goal of malaria elimination in Lao People's Democratic Republic (PDR) by 2030. However, people with glucose-6-phosphate dehydrogenase (G...

journal_title：Malaria journal

authors： Ong KIC,Iwagami M,Araki H,Khattignavong P,Soundala P,Keomalaphet S,Prasayasith P,Lorpachan L,Xangsayalath P,Pongvongsa T,Hongvanthong B,Brey PT,Kano S,Jimba M

更新日期：2019-03-12 00:00:00

abstract：BACKGROUND:The receptors for adhesion of Plasmodium falciparum-infected red blood cells (RBC) in the placenta have been identified as chondroitin-4-sulphate (C4S) proteoglycans, and the more sulphate-rich chondroitin oligosaccharides have been reported to inhibit adhesion. Since the anti-malarial drug chloroquine accum...

journal_title：Malaria journal

authors： Bhattacharyya S,Solakyildirim K,Zhang Z,Linhardt RJ,Tobacman JK

更新日期：2009-12-17 00:00:00

abstract：:Genetic manipulation of malaria parasites remains an inefficient, time-consuming and resource-intensive process. Presented here is a set of methods for 96-well plate-based transfection and culture that improve the efficiency of genetic manipulation of Plasmodium falciparum. Compared to standard protocols plate-based t...

journal_title：Malaria journal

authors： Caro F,Miller MG,DeRisi JL

更新日期：2012-01-18 00:00:00

abstract：BACKGROUND:Complement (C) can be activated during malaria, C components consumed and inflammatory mediators produced. This has potential to impair host innate defence. METHODS:In a case-control study, C activation was assessed by measuring serum haemolytic activity (CH50), functional activity of each pathway and level...

journal_title：Malaria journal

authors： Nyakoe NK,Taylor RP,Makumi JN,Waitumbi JN

更新日期：2009-01-09 00:00:00

abstract：BACKGROUND:Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine (T) at the codon 76. Previous studies have shown that microsatellite (MS) haplotype variation can be used to study the evolution o...

journal_title：Malaria journal

authors： DaRe JT,Mehlotra RK,Michon P,Mueller I,Reeder J,Sharma YD,Stoneking M,Zimmerman PA

更新日期：2007-03-21 00:00:00

abstract：BACKGROUND:There is growing concern that malaria vector resistance to pyrethroid insecticides may reduce the effectiveness of long-lasting insecticidal nets (LLINs). Combination LLINs are designed to control susceptible and pyrethroid-resistant mosquito populations through a mixture of pyrethroid with piperonyl butoxid...

journal_title：Malaria journal

authors： Cisse MBM,Sangare D,Oxborough RM,Dicko A,Dengela D,Sadou A,Mihigo J,George K,Norris L,Fornadel C

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Malaria can be eradicated from islands. To assess the prospects for eradication of malaria from the island of Príncipe in the Gulf of Guinea, we fitted a mathematical model to age-prevalence curves and thus obtained estimates of the vectorial capacity and of the basic reproductive number (R0) for malaria. M...

journal_title：Malaria journal

authors： Hagmann R,Charlwood JD,Gil V,Ferreira C,do Rosário V,Smith TA

更新日期：2003-06-18 00:00:00

abstract：BACKGROUND:Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmodium vivax malaria whe...

journal_title：Malaria journal

authors： Njokah MJ,Kang'ethe JN,Kinyua J,Kariuki D,Kimani FT

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:Increased control has produced remarkable reductions of malaria in some parts of sub-Saharan Africa, including Rwanda. In the southern highlands, near the district capital of Butare (altitude, 1,768 m), a combined community-and facility-based survey on Plasmodium infection was conducted early in 2010. METHO...

journal_title：Malaria journal

authors： Gahutu JB,Steininger C,Shyirambere C,Zeile I,Cwinya-Ay N,Danquah I,Larsen CH,Eggelte TA,Uwimana A,Karema C,Musemakweri A,Harms G,Mockenhaupt FP

更新日期：2011-05-18 00:00:00

abstract：BACKGROUND:The objective of this study to detect Plasmodium and a subspecies of Plasmodium using filter paper in malaria endemic province, Sanliurfa, in Turkey, compare the results of nested PCR (nPCR) with microscopy for the diagnosis of malaria and present the epidemiological data of malaria. METHODS:This study was ...

journal_title：Malaria journal

authors： Yentur Doni N,Yildiz Zeyrek F,Seyrek A

更新日期：2016-05-28 00:00:00

abstract：BACKGROUND:Severe malaria has been attributed to the expression of a restricted subset of the var multi-gene family, which encodes for Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 mediates cytoadherence and sequestration of infected erythrocytes into the post-capillary venules of vital organs s...

journal_title：Malaria journal

authors： Mugasa J,Qi W,Rusch S,Rottmann M,Beck HP

更新日期：2012-07-16 00:00:00

abstract：BACKGROUND:Information is needed on the expected durability of insecticidal nets under operational conditions. The persistence of insecticidal efficacy is important to estimate the median serviceable life of nets under field conditions and to plan for net replacement. METHODS:Deltamethrin residue levels were evaluated...

journal_title：Malaria journal

authors： Anshebo GY,Graves PM,Smith SC,Wills AB,Damte M,Endeshaw T,Shargie EB,Gebre T,Mosher AW,Patterson AE,Emerson PM

更新日期：2014-03-06 00:00:00

abstract：BACKGROUND:Anopheles nuneztovari sensu lato comprises cryptic species in northern South America, and the Brazilian populations encompass distinct genetic lineages within the Brazilian Amazon region. This study investigated, based on two molecular markers, whether these lineages might actually deserve species status. M...

journal_title：Malaria journal

authors： Scarpassa VM,Cunha-Machado AS,Saraiva JF

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDT) and real-time PCR (qPCR) assays are sensitive for diagnosing malaria, but because they detect antigen and DNA, respectively, positivity may not reflect active infection. Performance characteristics of RDT and qPCR in Plasmodium falciparum positive specimens were evaluated over ti...

journal_title：Malaria journal

authors： Phuong M,Lau R,Ralevski F,Boggild AK

更新日期：2015-09-17 00:00:00

abstract：BACKGROUND:Mosquito-feeding assays are important tools to guide the development and support the evaluation of transmission-blocking interventions. These functional bioassays measure the sporogonic development of gametocytes in blood-fed mosquitoes. Measuring the infectivity of low gametocyte densities has become increa...

journal_title：Malaria journal

authors： Reuling IJ,Stone WJR,van de Vegte-Bolmer M,van Gemert GJ,Siebelink-Stoter R,Graumans W,Lanke K,Bousema T,Sauerwein RW

更新日期：2017-08-05 00:00:00

abstract：BACKGROUND:Increasing access to health care services is considered central to improving the health of populations. Existing reviews to understand factors affecting access to health care have focused on attributes of patients and their communities that act as 'barriers' to access, such as education level, financial and ...

journal_title：Malaria journal

authors： Kizito J,Kayendeke M,Nabirye C,Staedke SG,Chandler CI

更新日期：2012-02-23 00:00:00

abstract：BACKGROUND:Declining in clinical efficacy of artesunate-mefloquine combination has been documented in areas along the eastern border (Thai-Cambodian) of Thailand. In the present study, the clinical efficacy of the three-day combination regimen of artesunate-mefloquine as first-line treatment for acute uncomplicated fal...

journal_title：Malaria journal

authors： Na-Bangchang K,Ruengweerayut R,Mahamad P,Ruengweerayut K,Chaijaroenkul W

更新日期：2010-10-08 00:00:00

abstract：BACKGROUND:Rosette-formation of Plasmodium falciparum parasitized erythrocytes is of importance in the development of severe malaria. The parasite-derived molecule PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1), central to rosetting, is suggested to be included in a multimeric vaccine targeting severe di...

journal_title：Malaria journal

authors： Angeletti D,Albrecht L,Wahlgren M,Moll K

更新日期：2013-01-24 00:00:00

abstract：BACKGROUND:The objective of this work was to develop a model to predict malaria incidence in an area of unstable transmission by studying the association between environmental variables and disease dynamics. METHODS:The study was carried out in Karuzi, a province in the Burundi highlands, using time series of monthly ...

journal_title：Malaria journal

authors： Gomez-Elipe A,Otero A,van Herp M,Aguirre-Jaime A

更新日期：2007-09-24 00:00:00

abstract：BACKGROUND:Malaria was endemic in the Rhône-Alpes area of eastern France in the 19th century and life expectancy was particularly shortened in Alpine valleys. This study was designed to determine how the disease affected people in the area and to identify the factors influencing malaria transmission. METHODS:Demograph...

journal_title：Malaria journal

authors： Sérandour J,Girel J,Boyer S,Ravanel P,Lemperière G,Raveton M

更新日期：2007-08-29 00:00:00

abstract：BACKGROUND:Although it is well known that drug pressure selects for drug-resistant parasites, the role of transmission reduction by insecticide-treated bed nets (ITNs) on drug resistance remains unclear. In this study, the drug resistance profile of current and previous first-line anti-malarials in Kenya was assessed w...

journal_title：Malaria journal

authors： Shah M,Omosun Y,Lal A,Odero C,Gatei W,Otieno K,Gimnig JE,ter Kuile F,Hawley WA,Nahlen B,Kariuki S,Walker E,Slutsker L,Hamel M,Shi YP

更新日期：2015-02-14 00:00:00

abstract：BACKGROUND:Malaria continues to be a disease of massive burden in Africa, and the public health resources targeted at surveillance, prevention, control, and intervention comprise large outlays of expense. Malaria transmission is largely constrained by the suitability of the climate for Anopheles mosquitoes and Plasmodi...

journal_title：Malaria journal

authors： Ryan SJ,Lippi CA,Zermoglio F

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:As South Africa strives to achieve malaria elimination by 2018 (zero local cases) the country needs to strengthen its disease surveillance system by reducing the timeliness from case diagnosis to notification of key stakeholders in the malaria programme. This study evaluated the feasibility of a 24-h mobile ...

journal_title：Malaria journal

authors： Baloyi RE,Shandukani MB,Graffy R,Misiani E,Mayet N,Mabunda E,Mabuza A,Qwabe B,Ngwenyama B,Reddy C,Moonasar D

更新日期：2018-08-23 00:00:00

abstract：BACKGROUND:Rapid diagnosis and correct treatment of cases are the main objectives of control programs in malaria-endemic areas. METHODS AND RESULTS:To evaluate these criteria and in a comparative study, blood specimens were collected from 120 volunteers seeking care at the Malaria Health Center in Chahbahar district. ...

journal_title：Malaria journal

authors： Zakeri S,Najafabadi ST,Zare A,Djadid ND

更新日期：2002-02-08 00:00:00

abstract：BACKGROUND:Control of mosquitoes requires the ability to evaluate new insecticides and to monitor resistance to existing insecticides. Monitoring tools should be flexible and low cost so that they can be deployed in remote, resource poor areas. Ideally, a bioassay should be able to simulate transient contact between mo...

journal_title：Malaria journal

authors： Sternberg ED,Waite JL,Thomas MB

更新日期：2014-12-16 00:00:00

abstract：BACKGROUND:Thrombocytopaenia is the most frequent malaria-associated haematologic alteration observed with all five Plasmodium parasites causing disease in humans. Although not included in the World Health Organization criteria for severe Plasmodium falciparum malaria, severe thrombocytopaenia has been increasingly men...

journal_title：Malaria journal

authors： Antinori S,Corona A,Ridolfo AL,Galimberti L,Ricaboni D,Milazzo L,Corbellino M

更新日期：2016-02-19 00:00:00