Expression level of the growth factor progranulin is related with development of systemic lupus erythematosus.

abstract：:This study is an initial investigation on the capability of multispectral imaging to capture subtle spectral information that would enable the automatic delineation between the eosinophilic esophagitis and other eosin stained tissue components, especially the RBCs. In the method, a principal component analysis (PCA) w...

journal_title：Diagnostic pathology

authors： Bautista PA,Yagi Y

更新日期：2011-03-30 00:00:00

abstract：UNLABELLED:Gastroenteropancreatic neuroendocrine tumors are the most incident neuroendocrine tumors. In the new WHO classification (2010) the embryological derivation of each neoplastic entity is one of the most important parameters. Gangliocytic Paraganglioma is a tumor originating in the hindgut, a rare neoplasm, gen...

journal_title：Diagnostic pathology

authors： Tatangelo F,Cantile M,Pelella A,Losito NS,Scognamiglio G,Bianco F,Belli A,Botti G

更新日期：2014-03-12 00:00:00

abstract：BACKGROUND:We report a case of a 33-year-old man who presented with immunoglobulin (Ig)G4-related disease (IgG4-RD) forming a pseudotumor in the left paratesticular region during oral administration of corticosteroid for Wells syndrome, which involves cellulitis with eosinophilia. CASE PRESENTATION:The patient was int...

journal_title：Diagnostic pathology

authors： Karashima T,Taniguchi Y,Shimamoto T,Nao T,Nishikawa H,Fukata S,Kamada M,Inoue K,Oko K,Nakajima H,Sano S,Matsumoto M,Kuroda N,Kamei Y,Shuin T

更新日期：2014-12-09 00:00:00

abstract：OBJECTIVE:FNA is a simple, safe, cost-effective and accurate diagnostic tool for the initial screening of patients with thyroid nodules. The aims of this study were to determine the diagnostic utility of FNAC performed in our institution, assess the cytomorphologic features that contribute to diagnostic errors and prop...

journal_title：Diagnostic pathology

authors： Zhu Y,Song Y,Xu G,Fan Z,Ren W

更新日期：2020-01-03 00:00:00

abstract：BACKGROUND:Ki67 is currently the proliferation biomarker of choice, with both prognostic and predictive value in breast cancer. A lack of consensus regarding Ki67 use in pre-analytical, analytical and post-analytical practice may hinder its formal acceptance in the clinical setting. METHODS:One hundred breast cancer s...

journal_title：Diagnostic pathology

authors： Romero Q,Bendahl PO,Fernö M,Grabau D,Borgquist S

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availability of high-quality images could substantially improve the efficacy of the diagnostic procedure. Co...

journal_title：Diagnostic pathology

authors： Elfgen C,Papassotiropoulos B,Varga Z,Moskovszky L,Nap M,Güth U,Baege A,Amann E,Chiesa F,Tausch C

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:We examined the vascularity of mammary Paget disease histologically to confirm the increased blood flow observed previously by clinical imaging. The relationships among blood vessel density (BVD), histopathological parameters of blood flow in the nipple, and the expression of angiogenic factors such as basic...

journal_title：Diagnostic pathology

authors： Akishima-Fukasawa Y,Honma N,Ogata H,Akasaka Y,Mikami T

更新日期：2020-06-11 00:00:00

abstract：BACKGROUND:PD-L1 is a glycoprotein from the family of T-cell co-stimulatory molecules that are constitutively expressed by macrophages. Aberrant expression of PD-L1 is observed in human cancers associated with inhibition of the tumor-directed T-cell immune response. There are few reports in the literature evaluating PD...

journal_title：Diagnostic pathology

authors： Leite KR,Reis ST,Junior JP,Zerati M,Gomes Dde O,Camara-Lopes LH,Srougi M

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:Somatostatin receptor 2 (SSTR2) encodes somatostatin receptor that can inhibit the cell proliferation of solid tumors. Promoter hypermethylation is likely to silence the expression of SSTR2. The goal of our study was to investigate the association between SSTR2 promoter methylation and the risk and progressi...

journal_title：Diagnostic pathology

authors： Shen Z,Chen X,Li Q,Zhou C,Li J,Ye H,Duan S

更新日期：2016-01-22 00:00:00

abstract：UNLABELLED:Imaging appearance of cyst-like changes is most frequently described in primary neuroendocrine lesions, especially pancreatic NETs.The imaging finding of a pseudocystic lesion of the liver puts in differential diagnosis many pathologies such as infectious diseases, simple biliary cysts up to biliary cystaden...

journal_title：Diagnostic pathology

authors： Fiori S,Del Gobbo A,Gaudioso G,Caccamo L,Massironi S,Cavalcoli F,Bosari S,Ferrero S

更新日期：2013-09-13 00:00:00

abstract：UNLABELLED:Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem in differential diagnosis with medulloblastoma and primitive neuroectodermal tumors. We present the ...

journal_title：Diagnostic pathology

authors： Mahdi Y,Kharmoum J,Alouan A,Elouarradi H,Elkhiyat I,Maher M,Benchrif MZ,Kili A,Daoudi R,Cherradi N

更新日期：2015-05-02 00:00:00

abstract：:This research was conducted on ten glass slides selected from the histopathology evaluation chickens. Five slides of control's chickens healthy and five slides of chickens infected experimentally with chicken anemia virus (CAV slide) between one and twenty-one days post infection (PI), they were analyzed in magnificat...

journal_title：Diagnostic pathology

authors： García L,Bermudez V,Brett M,Peroza L,Landa J,Borregales F

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:Metadherin (MTDH) has been reported to be associated with cancer progression in various types of human cancers including breast cancer. Whether MTDH contributes to carcinogenesis of breast cancer is still unknown. In the present study, we investigated the expression of MTDH in normal, UDH (usual ductal hyper...

journal_title：Diagnostic pathology

authors： Su P,Zhang Q,Yang Q

更新日期：2010-06-18 00:00:00

abstract：BACKGROUND:Acute promyelocytic leukemia is a cytogenetically well defined entity. Nevertheless, some features observed at diagnosis are related to a worse outcome of the patients. METHODS:In a prospective study, we analyzed peripheral (PB) leukocyte count, immunophenotype, methylation status of CDKN2B, CDKN2A and TP73...

journal_title：Diagnostic pathology

authors： De Mello MR,Albuquerque DM,Pereira-Cunha FG,Albanez KB,Pagnano KB,Costa FF,Metze K,Lorand-Metze I

更新日期：2012-06-28 00:00:00

abstract：:A 42-year-old male presented right upper abdomen pain for more than 6 days, which misdiagnose calculus of intrahepatic duct and acute cholecystitis. An approximately 1.5 cm x 1.0 cm x 1.0 cm nodule was found and resected in left lateral lobe of hepatic. Pathological examination showed spindle cell and fibroblast -like...

journal_title：Diagnostic pathology

authors： Liu Q,Liu J,Chen W,Mao S,Guo Y

更新日期：2013-12-02 00:00:00

abstract：BACKGROUND:c-MET is an oncogene protein that plays important role in gastric carcinogenesis and has been introduced as a prognostic marker and potential therapeutic target. The aim of this study was to evaluate the frequency of c-MET overexpression and its relationship with clinicopathological variables in gastric canc...

journal_title：Diagnostic pathology

authors： Sotoudeh K,Hashemi F,Madjd Z,Sadeghipour A,Molanaei S,Kalantary E

更新日期：2012-05-28 00:00:00

abstract：BACKGROUND:Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade tumour of salivary glands that was first described as a distinct entity in 1994 by Milchgrub et al. EWSR1-ATF1 fusion was found to be specific for this tumour. The majority of the reported cases of HCCC arise from minor salivary glands within the or...

journal_title：Diagnostic pathology

authors： AlAli BM,Alyousef MJ,Kamel AS,Al Hamad MA,Al-Bar MH,Algowiez RM

更新日期：2017-09-25 00:00:00

abstract：BACKGROUND/OBJECTIVE:Metastatic adenocarcinoma from an unknown primary site is a common clinical problem. Determining the cytokeratin (CK) 7/CK20 pattern of tumors is one of the most helpful procedures for this purpose since the CK7-/CK20+ pattern is typical of colorectal adenocarcinomas. CDX2, a critical nuclear trans...

journal_title：Diagnostic pathology

authors： Bayrak R,Haltas H,Yenidunya S

更新日期：2012-01-23 00:00:00

abstract：BACKGROUND:A recently published transcript set is suitable for gene expression-based discrimination of normal colonic and colorectal cancer (CRC) biopsy samples. Our aim was to test the discriminatory power of the CRC-specific transcript set on independent biopsies and on formalin-fixed, paraffin-embedded (FFPE) tissue...

journal_title：Diagnostic pathology

authors： Kalmár A,Wichmann B,Galamb O,Spisák S,Tóth K,Leiszter K,Nielsen BS,Barták BK,Tulassay Z,Molnár B

更新日期：2015-07-25 00:00:00

abstract：:Bronchoalveolar lavage (BAL) is a useful diagnostic tool in interstitial lung diseases (ILD). However, differential cell counts are often non specific and immunocytochemistry is time consuming. Staining of glycoproteins by periodic acid Schiff (PAS) reaction may help in discriminating different forms of ILD. In additi...

journal_title：Diagnostic pathology

authors： Hauber HP,Zabel P

更新日期：2009-04-23 00:00:00

abstract：BACKGROUND:Spontaneous isolated dissection of the superior mesenteric artery (SMA) can lead to bowel ischemia, aneurysm rupture, or even death. Studies have suggested that mechanical or hemodynamic stress on the vascular wall of the SMA may be a contributor, but its pathogenesis is unclear. CASE PRESENTATION:A 57-year...

journal_title：Diagnostic pathology

authors： Akuzawa N,Kurabayashi M,Suzuki T,Yoshinari D,Kobayashi M,Tanahashi Y,Makita F,Saito R

更新日期：2017-10-16 00:00:00

abstract：BACKGROUND:Mesonephric adenocarcinoma (MNAC) is a rare tumor of the female genital tract, which originates from mesonephric duct remnants. Its diagnosis is pathologically challenging, because MNAC may exhibit a mixture of morphological patterns that complicates the differential diagnosis. CASE PRESENTATION:The patient...

journal_title：Diagnostic pathology

authors： Montalvo N,Redrobán L,Galarza D

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:Branchial cleft anomalies constitute a frequently encountered and commonly non-lethal disease in otolaryngology, and result from aberrant embryonic development. The third branchial cleft fistula is one of the four known specific types of branchial cleft anomalies, and always presents as recurrent neck absces...

journal_title：Diagnostic pathology

authors： Tong F,Liang Y,Khan MF,Zhang L,Li W,Mahmoodurrahman M,Zhou Y

更新日期：2016-09-15 00:00:00

abstract：:Perivascular epithelioid cell tumor (PEComa) is a rare entity originating from mesenchymal tissue, which stains for both melanocytic and smooth muscle markers. We would like to present an unusual case of the PEComa of the mesentery which was unexpected discovery in a female patient with colonic adenocarcinoma. The tum...

journal_title：Diagnostic pathology

authors： Wejman J,Nowak K,Gielniewska L,Komorowska M,Dąbrowski W

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:To identify critical genes and biological pathways in acute lung injury (ALI), a comparative analysis of gene expression profiles of patients with ALI + sepsis compared with patients with sepsis alone were performed with bioinformatic tools. METHODS:GSE10474 was downloaded from Gene Expression Omnibus, incl...

journal_title：Diagnostic pathology

authors： Guo Z,Zhao C,Wang Z

更新日期：2014-09-26 00:00:00

abstract：BACKGROUND:Prostate cancer patients with rectal involvement are rare, and the factors associated with the survival of these patients are yet to be elucidated. PATIENTS AND METHODS:We collected data on patients who were admitted to our hospital for prostate cancer in the last thirteen years and of those in studies in t...

journal_title：Diagnostic pathology

authors： Wang H,Yao Y,Li B

更新日期：2014-02-20 00:00:00

abstract：BACKGROUND:Preventive and therapeutic options for renal failure are still limited. Gene expression profile analysis is powerful in the identification of biological differences between end stage renal failure patients and healthy controls. Previous studies mainly used variance/regression analysis without considering var...

journal_title：Diagnostic pathology

authors： Ding S,Xu Y,Hao T,Ma P

更新日期：2014-07-05 00:00:00

abstract：BACKGROUND:Human papillomavirus-associated oropharyngeal carcinoma (HPV-OPC) is clinicopathologically distinct entity from the HPV-unassociated one (nHPV-OPC). This study aimed to determine the relationship between histological subtypes of OPC and HPV status for Japanese cases and to identify histological structures of...

journal_title：Diagnostic pathology

authors： Fujimaki M,Fukumura Y,Mitani K,Kurisaki A,Yokoyama J,Ikeda K,Yao T

更新日期：2013-12-19 00:00:00

abstract：BACKGROUND:IgG4-TIN is the most common pattern of renal involvement in IgG4-related disease. There are several proposed diagnostic criteria of IgG4-TIN recently. Two of them proposed by the Mayo Clinic and JSN are predominant. However, histopathological criteria of the number of IgG4+ plasma cells and several histologi...

journal_title：Diagnostic pathology

authors： Tang X,Zhu B,Chen R,Hu Y,Zhang Y,Zhu X,Chen H,Wang Y

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Esophageal cancer is one of the leading causes of cancer related deaths among the Iranians. There is still a high ratio of mortality and low 5 years survival which are related to the late onset and diagnosis. Majority of patients refer for the treatment in advanced stages of tumor progression. MAIN BODY:It ...

journal_title：Diagnostic pathology

authors： Abbaszadegan MR,Keyvani V,Moghbeli M

更新日期：2019-08-31 00:00:00