A fatal case of severe neck abscess due to a third branchial cleft fistula: morphologic and immunohistochemical analyses.

abstract：BACKGROUND:The microRNAs present a class of non-coding RNAs which are usually implicated in tumor biology. Recent report has unraveled that a novel member of microRNA family called miR-1246. However, the functional role and molecular mechanisms of miR-1246 in non-small cell lung cancer (NSCLC) is still elusive. METHOD...

journal_title：Diagnostic pathology

authors： Huang W,Li H,Luo R

更新日期：2015-07-25 00:00:00

abstract：:Cellular Angiofibroma (CA) represents a quite recently described mesenchymal tumour that occurs in both genders, in particular in the vulvo-vaginal region in women and in the inguino-scrotal area in men. The first description of this tumour dates from Nucci et al. article in 1997; since then, the literature reports di...

journal_title：Diagnostic pathology

authors： Mandato VD,Santagni S,Cavazza A,Aguzzoli L,Abrate M,La Sala GB

更新日期：2015-07-19 00:00:00

abstract：BACKGROUND:The aim of this report is related to adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of the spermatic cord leiomyosarcoma. Primary paratesticular tumors are rare, only accounting for 7% to 10% of all intrascrotal tumors. In adults, more than 75% of these le...

journal_title：Diagnostic pathology

authors： Galosi AB,Scarpelli M,Mazzucchelli R,Lopez-Beltran A,Giustini L,Cheng L,Montironi R

更新日期：2014-05-06 00:00:00

abstract：UNLABELLED:Since first reported in 1986, 14 cases of extrauterine adenomyoma have been reported in the English literature, most often occurring in the ovaries. In this report, we present the first case of extrauterine adenomyoma involving the liver in a 29-year-old woman who presented with a 2-year history of low back ...

journal_title：Diagnostic pathology

authors： Huanwen W,Hui Z,Xiaowei X,Zhaohui L

更新日期：2013-08-05 00:00:00

abstract：BACKGROUND:Although often associated with holoprosencephaly, little detail of the histopathology of cyclopia is available. Here, we describe the ocular findings in a case of trisomy 13 to better understand the histogenesis of the rosettes, or tubules, characteristic of the retinal dysplasia associated with this conditi...

journal_title：Diagnostic pathology

authors： Chan A,Lakshminrusimha S,Heffner R,Gonzalez-Fernandez F

更新日期：2007-12-18 00:00:00

abstract：BACKGROUND:Malignant melanoma is the most lethal form of skin cancer with a variable clinical course even in patients with thin melanomas and localized disease. Despite increasing insights into melanoma biology, no prognostic biomarkers have yet been incorporated into clinical protocols. Reduced expression of the RNA b...

journal_title：Diagnostic pathology

authors： Nodin B,Fridberg M,Jonsson L,Bergman J,Uhlén M,Jirström K

更新日期：2012-07-17 00:00:00

abstract：:Meningioma, craniopharyngeoma and glioma are mainly intracranial lesions. Nevertheless, in rare cases these entities may occur solely as extracranial lesions that may present as intranasal/sinusoidal masses, with headaches and nasal obstruction. We present three cases of common intracranial tumors, with purely extracr...

journal_title：Diagnostic pathology

authors： Arndt S,Wiech T,Mader I,Aschendorff A,Maier W

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Esophageal cancer is one of the leading causes of cancer related deaths among the Iranians. There is still a high ratio of mortality and low 5 years survival which are related to the late onset and diagnosis. Majority of patients refer for the treatment in advanced stages of tumor progression. MAIN BODY:It ...

journal_title：Diagnostic pathology

authors： Abbaszadegan MR,Keyvani V,Moghbeli M

更新日期：2019-08-31 00:00:00

abstract：:Diagnostic surgical pathology or tissue–based diagnosis still remains the most reliable and specific diagnostic medical procedure. The development of whole slide scanners permits the creation of virtual slides and to work on so-called virtual microscopes. In addition to interactive work on virtual slides approaches ha...

journal_title：Diagnostic pathology

authors： Kayser K,Görtler J,Borkenfeld S,Kayser G

更新日期：2011-01-01 00:00:00

abstract：UNLABELLED:Gastroenteropancreatic neuroendocrine tumors are the most incident neuroendocrine tumors. In the new WHO classification (2010) the embryological derivation of each neoplastic entity is one of the most important parameters. Gangliocytic Paraganglioma is a tumor originating in the hindgut, a rare neoplasm, gen...

journal_title：Diagnostic pathology

authors： Tatangelo F,Cantile M,Pelella A,Losito NS,Scognamiglio G,Bianco F,Belli A,Botti G

更新日期：2014-03-12 00:00:00

abstract：BACKGROUND:To identify critical genes and biological pathways in acute lung injury (ALI), a comparative analysis of gene expression profiles of patients with ALI + sepsis compared with patients with sepsis alone were performed with bioinformatic tools. METHODS:GSE10474 was downloaded from Gene Expression Omnibus, incl...

journal_title：Diagnostic pathology

authors： Guo Z,Zhao C,Wang Z

更新日期：2014-09-26 00:00:00

abstract：UNLABELLED:Imaging appearance of cyst-like changes is most frequently described in primary neuroendocrine lesions, especially pancreatic NETs.The imaging finding of a pseudocystic lesion of the liver puts in differential diagnosis many pathologies such as infectious diseases, simple biliary cysts up to biliary cystaden...

journal_title：Diagnostic pathology

authors： Fiori S,Del Gobbo A,Gaudioso G,Caccamo L,Massironi S,Cavalcoli F,Bosari S,Ferrero S

更新日期：2013-09-13 00:00:00

abstract：BACKGROUND:Rhabdoid colorectal tumor (RCT) is a rare, highly aggressive neoplasm recurrent in elderly patients, commonly at the caecum. The molecular mechanisms underlying RCT pathogenesis remain poorly elucidated. The differential diagnosis is with the malignant rhabdoid tumors of infancy characterized by genetic inac...

journal_title：Diagnostic pathology

authors： Pancione M,Remo A,Sabatino L,Zanella C,Votino C,Fucci A,Di Blasi A,Lepore G,Daniele B,Fenizia F,Molinari E,Normanno N,Manfrin E,Vendraminelli R,Colantuoni V

更新日期：2013-02-20 00:00:00

abstract：UNLABELLED:Perivascular epithelioid cell tumors (PEComas) encompass a group of rare mesenchymal neoplasms, which typically have a perivascular location with dual melanocytic and muscular differentiation. They are found in a variety of localizations, though lesions in the liver are exceedingly rare. Because of their rar...

journal_title：Diagnostic pathology

authors： Ameurtesse H,Chbani L,Bennani A,Toughrai I,Beggui N,Kamaoui I,Elfatemi H,Harmouch T,Amarti A

更新日期：2014-07-17 00:00:00

abstract：BACKGROUND:Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described the detailed clinicop...

journal_title：Diagnostic pathology

authors： Yamada S,Kirishima M,Hiraki T,Higashi M,Hatanaka K,Tanimoto A

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Adult granulosa cell tumors of the ovary (GCTs) are sex cord stromal tumors of unpredictable behaviour. Up to now, the prediction of the relapsing/malignant potential remains difficult. CD56 (NCAM) in GCTs was previously described in only two studies. However, the expression of its isoforms was not examined....

journal_title：Diagnostic pathology

authors： Völker HU,Engert S,Cramer A,Schmidt M,Kämmerer U,Müller-Hermelink HK,Gattenlöhner S

更新日期：2008-07-09 00:00:00

abstract：BACKGROUND:The association between the Val158Met polymorphism in the catechol-O-methyltransferase (COMT) gene and lung cancer risk remains controversial and inconclusive. Therefore, the meta-analysis was performed to provide a quality reevaluation of the association between the COMT Val158Met polymorphism and the risk ...

journal_title：Diagnostic pathology

authors： Tan X,Chen M

更新日期：2014-10-04 00:00:00

abstract：UNLABELLED:We report a case of recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) in a 57-year-old male. The patient presented with papules and pruritus of the lower limbs of more than 1 month duration, and with angioedema and intensively pruritic, necrotizing lesions of the bilateral anterior tibias and f...

journal_title：Diagnostic pathology

authors： Li W,Cao W,Song H,Ciu Y,Lu X,Zhang F

更新日期：2013-11-07 00:00:00

abstract：BACKGROUND:Automated image analysis enables quantitative measurement of steatosis in histological images. However, spatial heterogeneity of steatosis can make quantitative steatosis scores unreliable. To improve the reliability, we have developed novel scores that are "focused" on steatotic tissue areas. METHODS:Focus...

journal_title：Diagnostic pathology

authors： Homeyer A,Hammad S,Schwen LO,Dahmen U,Höfener H,Gao Y,Dooley S,Schenk A

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:Nuclear protein in testis (NUT) midline carcinomas (NMC) are rare, highly aggressive epithelial neoplasms, characterised by protein expression of NUT-fusion proteins which reflects the genetic translocation between chromosome 15 and 19. NMC occurs mainly in midline structures, but there are reports regarding...

journal_title：Diagnostic pathology

authors： Lund-Iversen M,Grøholt KK,Helland Å,Borgen E,Brustugun OT

更新日期：2015-09-05 00:00:00

abstract：BACKGROUND:The transcriptional co-activator, TAZ, is an important effector of the Hippo pathway and is critical for the development of human cancers. However, the expression and prognostic significance of TAZ in retinoblastoma is currently unclear. METHODS:TAZ expression was examined in 43 retinoblastoma samples by im...

journal_title：Diagnostic pathology

authors： Zhang Y,Xue C,Cui H,Huang Z

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:High altitude pulmonary edema (HAPE) affects individuals and is characterized by alveolar flooding with protein-rich edema as a consequence of blood-gas barrier disruption. In this study, we hypothesized that aquaporin 5 (AQP5) which is one kind of water channels may play a role in preservation of alveolar e...

journal_title：Diagnostic pathology

authors： She J,Bi J,Tong L,Song Y,Bai C

更新日期：2013-11-25 00:00:00

abstract：:This study examined the effect of tissue section thickness and consistency--parameters outside the direct control of the imaging devices themselves--on WSI capture speed and image quality. Preliminary data indicates that thinner, more consistent tissue sectioning (such as those produced by automated tissue sectioning ...

journal_title：Diagnostic pathology

authors： Yagi Y,Gilbertson JR

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:c-MET is an oncogene protein that plays important role in gastric carcinogenesis and has been introduced as a prognostic marker and potential therapeutic target. The aim of this study was to evaluate the frequency of c-MET overexpression and its relationship with clinicopathological variables in gastric canc...

journal_title：Diagnostic pathology

authors： Sotoudeh K,Hashemi F,Madjd Z,Sadeghipour A,Molanaei S,Kalantary E

更新日期：2012-05-28 00:00:00

abstract：:Sclerosing rhabdomyosarcoma (SRMS) is an infrequent variant of rhabdomyosarcoma characterized by extensive intercellular hyaline fibrosis. We report the case of a 37 year-old male with a 9 x 6 cm SRMS on the right elbow. Histologically, the tumor showed an abundant extracellular hyaline matrix with extratumoral vascul...

journal_title：Diagnostic pathology

authors： Martorell M,Ortiz CM,Garcia JA

更新日期：2010-08-11 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) is one of the most powerful genetic analysis tools for pathological diagnoses. FISH can detect various genetic abnormalities including gene translocation that was specifically found in translocation-related sarcomas (TRSs). Here, we report the use of FISH in expert r...

journal_title：Diagnostic pathology

authors： Sugita S,Asanuma H,Hasegawa T

更新日期：2016-04-12 00:00:00

abstract：OBJECTIVES:RAD51 gene plays an important role in the pathogenesis of squamous cell carcinoma of the head and neck (SCCHN), colorectal cancer, ovarian cancer and acute leukaemia. A number of studies assessed the association between RAD51 135G/C polymorphism and the risk of these cancers in different population. However,...

journal_title：Diagnostic pathology

authors： Cheng D,Shi H,Zhang K,Yi L,Zhen G

更新日期：2014-01-23 00:00:00

abstract：BACKGROUND:Intestinal metaplasia (IM) of the gastric mucosa is classified as complete (Type I) and incomplete IM (Type II and III) subtypes, which showed significantly different risk for developing to gastric adenocarcinoma (GAC). GCRG213, a variant of L1-endonuclease (L1-EN), first identified in our lab, was upregulat...

journal_title：Diagnostic pathology

authors： Duan X,Lian H,Li J,Wu B,Wang W,Wu T,Wang C,Dou Y,Zhou Z,Wang B,Xue L,Wang G

更新日期：2019-06-21 00:00:00

abstract：INTRODUCTION:Nemaline myopathy is a rare genetic muscle disorder defined by the presence of nemaline rods in the muscle fibre sarcoplasm. Congenital nemaline myopathy is the most serious form of the disease's spectrum. CASE PRESENTATION:The affected newborn has no spontaneous movement, fractures at birth and respirato...

journal_title：Diagnostic pathology

authors： Waisayarat J,Suriyonplengsaeng C,Khongkhatithum C,Rochanawutanon M

更新日期：2015-04-16 00:00:00

abstract：BACKGROUND:Mesonephric adenocarcinoma (MNAC) is a rare tumor of the female genital tract, which originates from mesonephric duct remnants. Its diagnosis is pathologically challenging, because MNAC may exhibit a mixture of morphological patterns that complicates the differential diagnosis. CASE PRESENTATION:The patient...

journal_title：Diagnostic pathology

authors： Montalvo N,Redrobán L,Galarza D

更新日期：2019-07-03 00:00:00