Cellular angiofibroma in women: a review of the literature.

Abstract:

:Cellular Angiofibroma (CA) represents a quite recently described mesenchymal tumour that occurs in both genders, in particular in the vulvo-vaginal region in women and in the inguino-scrotal area in men. The first description of this tumour dates from Nucci et al. article in 1997; since then, the literature reports different reviews and case report of this tumour in both genders, but no article specifically addressing CA treatment and follow-up in women. In this review we collected all 79 published female CA cases, analyzing the clinical, pathological and immunohistochemical features of the tumour.CA affects women mostly during the fifth decade of life, it is generally a small and asymptomatic mass that mainly arises in the vulvo-vaginal region, although there are reported pelvic and extra-pelvic cases. The treatment requires a simple local excision due to an extremely low ability to recurrent locally and no chance to metastasize. Throughout the immunohistochemical and pathological findings it is also easily possible a differential diagnosis from the other soft tissue tumours which affect the vulvo-vaginal area, such as spindle cell lipoma, solitary fibrous tumour, angiomyofibroblastoma and aggressive angiomyxoma.

journal_name

Diagn Pathol

journal_title

Diagnostic pathology

authors

Mandato VD,Santagni S,Cavazza A,Aguzzoli L,Abrate M,La Sala GB

doi

10.1186/s13000-015-0361-6

subject

Has Abstract

pub_date

2015-07-19 00:00:00

pages

114

issn

1746-1596

pii

10.1186/s13000-015-0361-6

journal_volume

10

pub_type

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