Recurrent cutaneous necrotizing eosinophilic vasculitis: a case report and review of the literature.

abstract：BACKGROUND:Human papillomavirus-associated oropharyngeal carcinoma (HPV-OPC) is clinicopathologically distinct entity from the HPV-unassociated one (nHPV-OPC). This study aimed to determine the relationship between histological subtypes of OPC and HPV status for Japanese cases and to identify histological structures of...

journal_title：Diagnostic pathology

authors： Fujimaki M,Fukumura Y,Mitani K,Kurisaki A,Yokoyama J,Ikeda K,Yao T

更新日期：2013-12-19 00:00:00

abstract：BACKGROUND:Esophageal cancer is one of the leading causes of cancer related deaths among the Iranians. There is still a high ratio of mortality and low 5 years survival which are related to the late onset and diagnosis. Majority of patients refer for the treatment in advanced stages of tumor progression. MAIN BODY:It ...

journal_title：Diagnostic pathology

authors： Abbaszadegan MR,Keyvani V,Moghbeli M

更新日期：2019-08-31 00:00:00

abstract：BACKGROUND:Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described the detailed clinicop...

journal_title：Diagnostic pathology

authors： Yamada S,Kirishima M,Hiraki T,Higashi M,Hatanaka K,Tanimoto A

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Although often associated with holoprosencephaly, little detail of the histopathology of cyclopia is available. Here, we describe the ocular findings in a case of trisomy 13 to better understand the histogenesis of the rosettes, or tubules, characteristic of the retinal dysplasia associated with this conditi...

journal_title：Diagnostic pathology

authors： Chan A,Lakshminrusimha S,Heffner R,Gonzalez-Fernandez F

更新日期：2007-12-18 00:00:00

abstract：BACKGROUND:The association between the Val158Met polymorphism in the catechol-O-methyltransferase (COMT) gene and lung cancer risk remains controversial and inconclusive. Therefore, the meta-analysis was performed to provide a quality reevaluation of the association between the COMT Val158Met polymorphism and the risk ...

journal_title：Diagnostic pathology

authors： Tan X,Chen M

更新日期：2014-10-04 00:00:00

abstract：BACKGROUND:Choriocarcinoma is a highly aggressive, malignant trophoblastic neoplasm that can be gestational or non-gestational in origin. Accurate discrimination between these two subtypes, the causative pregnancy type, and the pregnancy-to-treatment interval for gestational choriocarcinoma are vital for clinical manag...

journal_title：Diagnostic pathology

authors： Zhang X,Yan K,Chen J,Xie X

更新日期：2019-08-17 00:00:00

abstract：BACKGROUND:Primary central nervous system (CNS) diffuse large B-cell lymphoma (DLBCL) is a rare intracranial tumor, defined as DLBCL arising from the brain, spinal cord, leptomeninges and eye, with an overall annual incidence of 5 cases per million. The primary CNS anaplastic variant of DLBCL (A-DLBCL) is even less com...

journal_title：Diagnostic pathology

authors： Xu T,Jia Q,Wang Y,Liu Y,Han D,Li P,Ma J,Fan L,Yan Q,Guo S,Li M,Wang Z

更新日期：2019-05-20 00:00:00

abstract：BACKGROUND:Ischemia/reperfusion (I/R) injury of heart is one of the major causes of acute cardiac injury, which may result in worsening or even loss of heart function. With novel microRNAs being evolutionarily discovered, numbers of them remained functionally unknown. We aimed to discover novel microRNAs with therapeut...

journal_title：Diagnostic pathology

authors： Chen Y,Ye X,Yan F

更新日期：2019-10-31 00:00:00

abstract：BACKGROUND:Advancing knowledge in molecular pathogenesis of hepatocellular carcinoma (HCC) opens up new horizons in the diagnostic, prognostic and therapeutic perspectives. Assessing the expression of molecular targets prior to definitive treatment is gaining importance in clinical practice. In this study, we investiga...

journal_title：Diagnostic pathology

authors： Lo RC,Leung CO,Chok KS,Ng IO

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:We report a case of a 33-year-old man who presented with immunoglobulin (Ig)G4-related disease (IgG4-RD) forming a pseudotumor in the left paratesticular region during oral administration of corticosteroid for Wells syndrome, which involves cellulitis with eosinophilia. CASE PRESENTATION:The patient was int...

journal_title：Diagnostic pathology

authors： Karashima T,Taniguchi Y,Shimamoto T,Nao T,Nishikawa H,Fukata S,Kamada M,Inoue K,Oko K,Nakajima H,Sano S,Matsumoto M,Kuroda N,Kamei Y,Shuin T

更新日期：2014-12-09 00:00:00

abstract：BACKGROUND:Metadherin (MTDH) has been reported to be associated with cancer progression in various types of human cancers including breast cancer. Whether MTDH contributes to carcinogenesis of breast cancer is still unknown. In the present study, we investigated the expression of MTDH in normal, UDH (usual ductal hyper...

journal_title：Diagnostic pathology

authors： Su P,Zhang Q,Yang Q

更新日期：2010-06-18 00:00:00

abstract：BACKGROUND:Assessment of hemoglobin is one of the most reliable indicators for anemia, and is widely used to screen for anemia among pregnant women. The HemoCue® has been widely used for as a point-of-care device for hemoglobin estimation in health facilities. Previous studies showed contradictory results regarding the...

journal_title：Diagnostic pathology

authors： Adam I,Ahmed S,Mahmoud MH,Yassin MI

更新日期：2012-03-21 00:00:00

abstract：BACKGROUND:Reduced DNA repair capacities due to inherited polymorphisms may increase the susceptibility to cancers including gastric cancer. Previous studies investigating the association between Xeroderma Pigmentosum group C (XPC) gene polymorphisms and gastric cancer risk reported inconsistent results. We performed a...

journal_title：Diagnostic pathology

authors： Peng Q,Chen Z,Lu Y,Lao X,Mo C,Li R,Qin X,Li S

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:Metastatic spread of tumor through lymphatic vasculature is an important adverse prognostic factor in a variety of human cancer and tumor lymphangiogenesis requires the interplay of several growth factors. Platelet-derived growth factor (PDGF)-BB and vascular endothelial growth factor (VEGF)-C are two import...

journal_title：Diagnostic pathology

authors： Liu J,Liu C,Qiu L,Li J,Zhang P,Sun Y

更新日期：2014-06-27 00:00:00

abstract：:This study is an initial investigation on the capability of multispectral imaging to capture subtle spectral information that would enable the automatic delineation between the eosinophilic esophagitis and other eosin stained tissue components, especially the RBCs. In the method, a principal component analysis (PCA) w...

journal_title：Diagnostic pathology

authors： Bautista PA,Yagi Y

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:HER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti-HER2/neu treatment. METHODS:We systematically evaluated the HER2/n...

journal_title：Diagnostic pathology

authors： Woo JS,Apple SK,Sullivan PS,Rao JY,Ostrzega N,Moatamed NA

更新日期：2016-10-22 00:00:00

abstract：BACKGROUND:Several studies reported the dysregulation of miR-541 in the progression of some human malignancies. Osteosarcoma (OS) is one of the most common primary malignant bone tumors. This study aimed to assess the expression and clinical significance of miR-541 in OS patients and explore the biological function of ...

journal_title：Diagnostic pathology

authors： Liu C,Yi X

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:Human kallikrein gene 6 (KLK6) is a member of the human kallikrein gene family (Kallikreins, KLKs). Human kallikrein-related peptidase 6 (hK6) is a trypsin-like serine protease encoded by the KLK6, has been reported to be highly expressed in several cancers including gastric cancer. In this study, we investi...

journal_title：Diagnostic pathology

authors： Liu X,Xiong H,Li J,He Y,Yuan X

更新日期：2013-04-15 00:00:00

abstract：:A transrectal needle biopsy from a 63-year-old man was decided because of a high prostatic specific antigen in the blood, and a hard right lobe in rectal examination. 10 examples were taken from each lobe. In 1 of 4 of the examples from the left lobe, which contained a small focus of adenocarcinoma, numerous eosinophi...

journal_title：Diagnostic pathology

authors： Aydin O

更新日期：2006-09-07 00:00:00

abstract：BACKGROUND:The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily Afr...

journal_title：Diagnostic pathology

authors： Wang H,Tsang P,D'Cruz C,Clarke K

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:Maspin is a unique member of the serine protease inhibitor superfamily and its expression is found in myoepithelial cells of normal mammary glands; therefore, it has been considered to be a myoepithelial marker. We previously reported that maspin was frequently expressed in biologically aggressive breast can...

journal_title：Diagnostic pathology

authors： Umekita Y,Ohi Y,Souda M,Rai Y,Sagara Y,Sagara Y,Tamada S,Tanimoto A

更新日期：2011-04-16 00:00:00

abstract：BACKGROUND:We examined the vascularity of mammary Paget disease histologically to confirm the increased blood flow observed previously by clinical imaging. The relationships among blood vessel density (BVD), histopathological parameters of blood flow in the nipple, and the expression of angiogenic factors such as basic...

journal_title：Diagnostic pathology

authors： Akishima-Fukasawa Y,Honma N,Ogata H,Akasaka Y,Mikami T

更新日期：2020-06-11 00:00:00

abstract：BACKGROUND:The polymorphism Pro12Ala in peroxisome proliferator-activated receptor-γ2 gene (PPARγ2) has been reported to be associated with diabetic nephropathy (DN) in some studies, though the results remain inconclusive. To explore this relationship between PPARγ2 Pro12Ala polymorphism and the susceptibility for DN, ...

journal_title：Diagnostic pathology

authors： Wang L,Teng Z,Cai S,Wang D,Zhao X,Yu K

更新日期：2013-07-15 00:00:00

abstract：UNLABELLED:Cutaneous mast cell tumours (MCTs) are the most common skin tumours in dogs. Due to the prevalence of canine MCTs and the variable biologic behavior of this disease, accurate prognostication and a thorough understanding of MCT biology are critical for the treatment of this disease. A cytologic diagnosis of m...

journal_title：Diagnostic pathology

authors： Hosseini E,Pedram B,Bahrami AM,Moghaddam MH,Javanbakht J,Ghomi FE,Moghaddam NJ,Koohestani M,Shafiee R

更新日期：2014-01-20 00:00:00

abstract：BACKGROUND:Primary diffuse large B cell lymphoma (DLBCL) of the uterus is rare, and primary DLBCL arising from a uterine leiomyoma (collision tumor) has not been reported in the literature. CASE PRESENTATION:We describe the clinical, histological, immunohistochemical, and molecular features of primary DLBCL arising fr...

journal_title：Diagnostic pathology

authors： Zhao L,Ma Q,Wang Q,Zeng Y,Luo Q,Xiao H

更新日期：2016-01-20 00:00:00

abstract：BACKGROUND:Mixed adeno-neuroendocrine carcinoma (MANEC) of the biliary tract is rare with only a few reported cases. Consequently, knowledge about their pathogenesis, histopathological characteristics and outcomes is sparce. CASE PRESENTATION:A 53-year old man presented with epigastric pain on a background of excessiv...

journal_title：Diagnostic pathology

authors： Zheng SL,Yip VS,Pedica F,Prachalias A,Quaglia A

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:Glomus tumors typically occur in the subcutaneous tissue of distal extremities, but rarely in visceral organs. Most glomus tumors are benign, while others have been reported to have malignant potential. Herein, a unique case of a liver glomus tumor with atypical histological features is reported. CASE PRESE...

journal_title：Diagnostic pathology

authors： Hirose K,Matsui T,Nagano H,Eguchi H,Marubashi S,Wada H,Morii E

更新日期：2015-07-19 00:00:00

abstract：BACKGROUND:Rheumatoid Arthritis is a chronic disease leading to decreased quality of life with a rather variable response rate to Disease Modifying Anti Rheumatic Drugs. Methotrexate (MTX) is the gold standard therapy in Rheumatoid Arthritis. The Multidrug resistance Related Protein and Multi Drug Resistance protein 1,...

journal_title：Diagnostic pathology

authors： Micsik T,Lőrincz A,Gál J,Schwab R,Peták I

更新日期：2015-12-30 00:00:00

abstract：:A 42-year-old male presented right upper abdomen pain for more than 6 days, which misdiagnose calculus of intrahepatic duct and acute cholecystitis. An approximately 1.5 cm x 1.0 cm x 1.0 cm nodule was found and resected in left lateral lobe of hepatic. Pathological examination showed spindle cell and fibroblast -like...

journal_title：Diagnostic pathology

authors： Liu Q,Liu J,Chen W,Mao S,Guo Y

更新日期：2013-12-02 00:00:00

abstract：:Primary pleural angiosarcoma is a rare and clinically aggressive tumor. Patients usually present with chest pain, dyspnea, hemoptysis and/or cough. Radiologic studies reveal diffuse pleural thickening and pleural effusion with or without mass lesion. The clinical and radiological features both resemble those of mesoth...

journal_title：Diagnostic pathology

authors： Kao YC,Chow JM,Wang KM,Fang CL,Chu JS,Chen CL

更新日期：2011-12-30 00:00:00