Abstract：
BACKGROUND:We report a case of a 33-year-old man who presented with immunoglobulin (Ig)G4-related disease (IgG4-RD) forming a pseudotumor in the left paratesticular region during oral administration of corticosteroid for Wells syndrome, which involves cellulitis with eosinophilia. CASE PRESENTATION:The patient was introduced to our institution from a private hospital with a 3-month history of asymptomatic left scrotal mass. A 5-cm diameter nodule was palpable in the left scrotum. Tumor lesion in the left paratestis involving the epididymis and spermatic cord was observed on computed tomography and magnetic resonance imaging. Blood testing showed no abnormalities other than a minimal increase in C-reactive protein levels. Urine examination likewise revealed no significant findings. Left radical orchidectomy was performed under a diagnosis of left paratesticular neoplasm suspected as malignant tumor. The tumor was pathologically identified as IgG4-RD of the left paratestis involving the epididymis and spermatic cord. CONCLUSIONS:We present a first description of IgG4-RD in a patient with Wells syndrome and the ninth case of IgG4-RD in a scrotal organ, and discuss this very rare entity with reference to the literature. VIRTUAL SLIDES:The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/13000_2014_225.
journal_name
Diagn Patholjournal_title
Diagnostic pathologyauthors
Karashima T,Taniguchi Y,Shimamoto T,Nao T,Nishikawa H,Fukata S,Kamada M,Inoue K,Oko K,Nakajima H,Sano S,Matsumoto M,Kuroda N,Kamei Y,Shuin Tdoi
10.1186/s13000-014-0225-5subject
Has Abstractpub_date
2014-12-09 00:00:00pages
225issn
1746-1596pii
s13000-014-0225-5journal_volume
9pub_type
杂志文章,评审abstract：BACKGROUND:To quantify the effect of cruciferous vegetable consumption on the incidence of ovarian cancer by meta-analyzing the existing observational studies and provides quantitative and high-level evidence. METHODS:A detailed literature search of Medline and EMBASE for all relevant papers published. A meta-analysis...
journal_title：Diagnostic pathology
pub_type： 杂志文章,meta分析
doi：10.1186/1746-1596-9-7
更新日期：2014-01-20 00:00:00
abstract：BACKGROUND:Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availability of high-quality images could substantially improve the efficacy of the diagnostic procedure. Co...
journal_title：Diagnostic pathology
pub_type： 杂志文章
doi：10.1186/s13000-019-0835-z
更新日期：2019-06-15 00:00:00
abstract：BACKGROUND:Metastatic spread of tumor through lymphatic vasculature is an important adverse prognostic factor in a variety of human cancer and tumor lymphangiogenesis requires the interplay of several growth factors. Platelet-derived growth factor (PDGF)-BB and vascular endothelial growth factor (VEGF)-C are two import...
journal_title：Diagnostic pathology
pub_type： 杂志文章
doi：10.1186/1746-1596-9-128
更新日期：2014-06-27 00:00:00
abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, mainly due to its high rates of postoperative recurrence and metastasis. Please remove, it currently ranks as the third most common cause of cancer-related deaths. MiRNAs are a set of small, single-stranded, non-coding RNA m...
journal_title：Diagnostic pathology
pub_type： 杂志文章,收录出版
doi：10.1186/s13000-015-0371-4
更新日期：2015-08-07 00:00:00
abstract：OBJECTIVES:RAD51 gene plays an important role in the pathogenesis of squamous cell carcinoma of the head and neck (SCCHN), colorectal cancer, ovarian cancer and acute leukaemia. A number of studies assessed the association between RAD51 135G/C polymorphism and the risk of these cancers in different population. However,...
journal_title：Diagnostic pathology
pub_type： 杂志文章,meta分析
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更新日期：2014-01-23 00:00:00
abstract：BACKGROUND:Preventive and therapeutic options for renal failure are still limited. Gene expression profile analysis is powerful in the identification of biological differences between end stage renal failure patients and healthy controls. Previous studies mainly used variance/regression analysis without considering var...
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pub_type： 杂志文章
doi：10.1186/1746-1596-9-137
更新日期：2014-07-05 00:00:00
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journal_title：Diagnostic pathology
pub_type： 杂志文章
doi：10.1186/s13000-015-0406-x
更新日期：2015-09-17 00:00:00
abstract：BACKGROUND:Branchial cleft anomalies constitute a frequently encountered and commonly non-lethal disease in otolaryngology, and result from aberrant embryonic development. The third branchial cleft fistula is one of the four known specific types of branchial cleft anomalies, and always presents as recurrent neck absces...
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pub_type： 杂志文章
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更新日期：2016-09-15 00:00:00
abstract：BACKGROUND:Human papillomavirus-associated oropharyngeal carcinoma (HPV-OPC) is clinicopathologically distinct entity from the HPV-unassociated one (nHPV-OPC). This study aimed to determine the relationship between histological subtypes of OPC and HPV status for Japanese cases and to identify histological structures of...
journal_title：Diagnostic pathology
pub_type： 杂志文章
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更新日期：2013-12-19 00:00:00
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更新日期：2020-04-01 00:00:00
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更新日期：2020-11-20 00:00:00
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更新日期：2015-12-16 00:00:00
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journal_title：Diagnostic pathology
pub_type： 杂志文章
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更新日期：2011-12-30 00:00:00
abstract：:A case of prenatally diagnosed, giant cord hemangioma is reported, which was accompanied by the elevation of maternal serum alpha-fetoprotein (MS-AFP) and human chorionic gonadotropin (MS-hCG) levels. A 30-year-old woman without a previous history of gravida or para, presented with intermittent abdominal pain at 26 we...
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更新日期：2015-09-04 00:00:00
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pub_type： 杂志文章
doi：10.1186/s13000-016-0495-1
更新日期：2016-05-25 00:00:00
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更新日期：2020-10-06 00:00:00
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journal_title：Diagnostic pathology
pub_type： 杂志文章
doi：10.1186/1746-1596-9-54
更新日期：2014-03-12 00:00:00
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更新日期：2015-04-02 00:00:00
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doi：10.1186/1746-1596-1-37
更新日期：2006-10-17 00:00:00
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doi：10.1186/1746-1596-7-38
更新日期：2012-04-12 00:00:00
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更新日期：2021-01-09 00:00:00
abstract：BACKGROUND:Chronic hepatitis B virus (HBV) infection is a known major etiological factor for hepatocellular carcinoma (HCC) development. Alpha-fetoprotein (AFP) is widely used to detect primary HCC, whereas its sensitivity and specificity are not satisfying. Recently, circulating microRNAs (miRNAs) have been reported t...
journal_title：Diagnostic pathology
pub_type： 杂志文章
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更新日期：2015-07-28 00:00:00
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pub_type： 杂志文章,评审
doi：10.1186/s13000-019-0802-8
更新日期：2019-04-09 00:00:00
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journal_title：Diagnostic pathology
pub_type： 杂志文章,meta分析,评审
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更新日期：2012-08-13 00:00:00
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journal_title：Diagnostic pathology
pub_type： 杂志文章
doi：10.1186/s13000-017-0664-x
更新日期：2017-10-16 00:00:00
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journal_title：Diagnostic pathology
pub_type： 杂志文章
doi：10.1186/1746-1596-6-s1-s12
更新日期：2011-01-01 00:00:00
abstract：UNLABELLED:Metastatic renal cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews. Only 40 cases were reported in the literature. We report a first case of gallbladder polypoid tumor revealing metastatic clear cell renal cell carcinoma, which demonstra...
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pub_type： 杂志文章,评审
doi：10.1186/1746-1596-8-4
更新日期：2013-01-10 00:00:00
