Focused scores enable reliable discrimination of small differences in steatosis.

abstract：BACKGROUND:High grade basal-like breast carcinomas are triple negative, express basal cytokeratins, and are known for the overall poor prognosis and aggressive behavior. HPV related multiphenotypic sino-nasal carcinoma has overlapping histology with basal-like breast carcinomas, but carry the defining feature of associ...

journal_title：Diagnostic pathology

authors： Oramas DM,Bell D,Middleton LP

更新日期：2020-11-20 00:00:00

abstract：:Endometriosis is a clinical entity characterized by the presence of normal endometrial mucosa abnormally implanted in locations other than the uterine cavity. Endometriosis can be either endopelvic or extrapelvic depending on the location of endometrial tissue implantation. Despite the rarity of extrapelvic endometrio...

journal_title：Diagnostic pathology

authors： Machairiotis N,Stylianaki A,Dryllis G,Zarogoulidis P,Kouroutou P,Tsiamis N,Katsikogiannis N,Sarika E,Courcoutsakis N,Tsiouda T,Gschwendtner A,Zarogoulidis K,Sakkas L,Baliaka A,Machairiotis C

更新日期：2013-12-02 00:00:00

abstract：INTRODUCTION:Necrobiosis lipoidica diabeticorum is a rare disease of unclear etiology, that occurs in about 1% of diabetic patients. CASE REPORT:We present case of granulomatosis disciformis chronica et progressiva Miescher with good response to systemic corticosteroids therapy.Patient 45 years old woman, with primary...

journal_title：Diagnostic pathology

authors： Bergler-Czop B,Brzezińska-Wcisło L,Rogala-Poborska I

更新日期：2009-08-28 00:00:00

abstract：:Perivascular epithelioid cell tumor (PEComa) is a rare entity originating from mesenchymal tissue, which stains for both melanocytic and smooth muscle markers. We would like to present an unusual case of the PEComa of the mesentery which was unexpected discovery in a female patient with colonic adenocarcinoma. The tum...

journal_title：Diagnostic pathology

authors： Wejman J,Nowak K,Gielniewska L,Komorowska M,Dąbrowski W

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Several studies reported the dysregulation of miR-541 in the progression of some human malignancies. Osteosarcoma (OS) is one of the most common primary malignant bone tumors. This study aimed to assess the expression and clinical significance of miR-541 in OS patients and explore the biological function of ...

journal_title：Diagnostic pathology

authors： Liu C,Yi X

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:Microsatellite-unstable colorectal cancers (CRC) that are due to deficient DNA mismatch repair (dMMR) represent approximately 15% of all CRCs in the United States. These microsatellite-unstable CRCs represent a heterogenous group of diseases with distinct oncogenesis pathways. There are overlapping clinicopa...

journal_title：Diagnostic pathology

authors： Chen W,Swanson BJ,Frankel WL

更新日期：2017-03-04 00:00:00

abstract：BACKGROUND:The histopathological subtype, nuclear grade and presence or absence of comedonecrosis are established as critical elements in the reporting of ductal carcinoma in situ (DCIS) of the breast. The aims of this study were to determine the frequencies of morphological subtypes of DCIS, nuclear grade and comedone...

journal_title：Diagnostic pathology

authors： Perez AA,Balabram D,Salles Mde A,Gobbi H

更新日期：2014-12-03 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated B-cell post-transplantation lymphoproliferative disorder (PTLD) is a severe complication following stem cell transplantation. This is believed to occur as a result of iatrogenic immunosuppression leading to a relaxation of T-cell control of EBV infection and thus allowing viral reac...

journal_title：Diagnostic pathology

authors： Krenauer A,Moll A,Pönisch W,Schmitz N,Niedobitek G,Niederwieser D,Aigner T

更新日期：2010-03-31 00:00:00

abstract：BACKGROUND:Crystalloid podocytopathy with focal segmental glomerulosclerosis in plasma cell myeloma (PCM) is rare. CASE PRESENTATION:We present a case of crystalline deposition in the bone marrow (BM) and various renal cells with only proteinuria as a symptom. As workup for proteinuria, a renal biopsy sample was obtai...

journal_title：Diagnostic pathology

authors： Jeon YL,Lee WI,Choi Y,Kang SY,Kim MH,Lim SJ,Lee SH

更新日期：2015-12-16 00:00:00

abstract：:Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute myeloid leukemia (AML) and T lymphoblastic lymphoma. The bone marrow chromosome analysis showed the karyotype 46, XY, t(5;12)(q33;p13), which indicated presence of PDGFRB gene translocations. Therefore, this disease belo...

journal_title：Diagnostic pathology

authors： Chang H,Chuang WY,Sun CF,Barnard MR

更新日期：2012-02-22 00:00:00

abstract：BACKGROUND:In recent years, a battery-powered bone marrow biopsy system was developed and cleared by the U.S. Food and Drug Administration to allow health care providers to access the bone marrow space quickly and efficiently. A multicenter randomized clinical trial was designed for adult patients to determine if the p...

journal_title：Diagnostic pathology

authors： Berenson JR,Yellin O,Blumenstein B,Bojanower D,Croopnick J,Aboulafia D,Upadhyaya G,Spadaccini C

更新日期：2011-03-23 00:00:00

abstract：OBJECTIVE:MicroRNA-100 (miR-100) has been demonstrated to be downregulated in bladder cancer tissues, and enforced expression of this miRNA may inhibit cell growth and colony formation of human bladder cancer 5637 cells in vitro. However, the clinical significance of miR-100 in human bladder cancer has not yet been elu...

journal_title：Diagnostic pathology

authors： Wang S,Xue S,Dai Y,Yang J,Chen Z,Fang X,Zhou W,Wu W,Li Q

更新日期：2012-11-22 00:00:00

abstract：UNLABELLED:Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem in differential diagnosis with medulloblastoma and primitive neuroectodermal tumors. We present the ...

journal_title：Diagnostic pathology

authors： Mahdi Y,Kharmoum J,Alouan A,Elouarradi H,Elkhiyat I,Maher M,Benchrif MZ,Kili A,Daoudi R,Cherradi N

更新日期：2015-05-02 00:00:00

abstract：OBJECTIVES:This study consisted of two parts. One part was to analyze the survival rates of adenoid cystic carcinoma (ACC) in Chinese and explain the difference between our data and the literature. The other was to analyze the relationship between the expression of CD117 and the histological grade and the prognosis. M...

journal_title：Diagnostic pathology

authors： Zhou Q,Chang H,Zhang H,Han Y,Liu H

更新日期：2012-09-10 00:00:00

abstract：BACKGROUND:Hypermethylation of the promoter region of the RAS association domain family 1A gene (RASSF1A) occurs widely in hepatocellular carcinoma (HCC) tissues. While the diagnostic performance of the use of RASSF1A methylation as a serum or plasma marker in patients with HCC has varied largely in the literature,we c...

journal_title：Diagnostic pathology

authors： Dong X,He H,Zhang W,Yu D,Wang X,Chen Y

更新日期：2015-08-04 00:00:00

abstract：BACKGROUND:It is not clear if sentinel lymph node (SLN) mapping can improve outcomes in patients with colorectal cancers. The purpose of this study was to determine the prognostic values of ex vivo sentinel lymph node (SLN) mapping and immunohistochemical (IHC) detection of SLN micrometastasis in colorectal cancers. M...

journal_title：Diagnostic pathology

authors： Wang FL,Shen F,Wan DS,Lu ZH,Li LR,Chen G,Wu XJ,Ding PR,Kong LH,Pan ZZ

更新日期：2012-06-22 00:00:00

abstract：:Diagnostic surgical pathology or tissue–based diagnosis still remains the most reliable and specific diagnostic medical procedure. The development of whole slide scanners permits the creation of virtual slides and to work on so-called virtual microscopes. In addition to interactive work on virtual slides approaches ha...

journal_title：Diagnostic pathology

authors： Kayser K,Görtler J,Borkenfeld S,Kayser G

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The outbreak of a novel coronavirus since December 2019, became an emergency of major international concern. As of June 21, 2020, the SARS-CoV-2 pandemic has caused 8,769,844 confirmed infections with 463,745 fatal cases worldwide. The SARS-CoV-2 outbreak is a major challenge for clinicians. In our clinic, w...

journal_title：Diagnostic pathology

authors： Zhai P,Ding Y,Li Y

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Human papillomavirus-associated oropharyngeal carcinoma (HPV-OPC) is clinicopathologically distinct entity from the HPV-unassociated one (nHPV-OPC). This study aimed to determine the relationship between histological subtypes of OPC and HPV status for Japanese cases and to identify histological structures of...

journal_title：Diagnostic pathology

authors： Fujimaki M,Fukumura Y,Mitani K,Kurisaki A,Yokoyama J,Ikeda K,Yao T

更新日期：2013-12-19 00:00:00

abstract：:Perivascular epithelioid cell (PEC) tumors (PEComas) are a family of related mesenchymal tumors composed of PECs which co-express melanocytic and smooth muscle markers. Although their distinctive histologic, immunohistochemical, ultrastructural, and genetic features have been clearly demonstrated, their histogenesis a...

journal_title：Diagnostic pathology

authors： Fang CL,Lin YH,Chen WY

更新日期：2012-09-03 00:00:00

abstract：BACKGROUND:World Health Organization (WHO) criteria are commonly used to diagnose plasma cell myeloma (PCM); however, these criteria are complex and require several laboratory parameters. For differentiating reactive plasmacytosis from clonal plasma cell (PC) neoplasms such as PCM, it is important to accurately determi...

journal_title：Diagnostic pathology

authors： Nakayama S,Yokote T,Hirata Y,Iwaki K,Akioka T,Miyoshi T,Takayama A,Nishiwaki U,Masuda Y,Ikemoto T,Tanaka H,Nishimura Y,Tsuji M,Hanafusa T

更新日期：2012-09-28 00:00:00

abstract：OBJECTIVES:Non-Hodgkin's lymphoma (NHL) primarily derived from the base of the tongue, is rare. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are important aetiological risk factors for tumours of the head and neck. This study describes the clinicopathological features of NHL in the tongue base and the status...

journal_title：Diagnostic pathology

authors： Ren X,Cheng Y,Wu S,Zeng X,Shi X,Ling Q,Li Z,Liang Z,Wang B

更新日期：2020-04-01 00:00:00

abstract：:Endocervicosis in the urinary bladder is a rare benign condition. We present a case in a 37-year-old woman with classical clinical and pathological features of endocervicosis. The unusual observation of endocervical-like mucinous epithelium in continuity with the urothelium in addition to fully developed endocervicosi...

journal_title：Diagnostic pathology

authors： Cheah PL,Looi LM,Lee GE,Teoh KH,Mun KS,Nazarina AR

更新日期：2011-06-23 00:00:00

abstract：UNLABELLED:Giant cell angioblastoma (GCAB) is an extremely rare soft tissue tumor of early childhood and only five cases have been described to date. As such the clinical, pathological, and prognostic features are poorly defined. We prensent here a new case of GCAB in bone of a child aged 4-years old. The lesion was co...

journal_title：Diagnostic pathology

authors： Mao RJ,Jiang ZM,Zhang HZ,Zhu XZ,Zhang QL

更新日期：2012-08-29 00:00:00

abstract：BACKGROUND:Mesonephric-like adenocarcinoma (M-LAC) is a rare, recently described tumor occurring in the uterine corpus and ovary, which shares the same morphological and immunohistochemical features with the more common mesonephric adenocarcinoma (MAC), which mostly arises the uterine cervix. Despite the similarities b...

journal_title：Diagnostic pathology

authors： Dundr P,Gregová M,Němejcová K,Bártů M,Hájková N,Hojný J,Stružinská I,Fischerová D

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:HER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti-HER2/neu treatment. METHODS:We systematically evaluated the HER2/n...

journal_title：Diagnostic pathology

authors： Woo JS,Apple SK,Sullivan PS,Rao JY,Ostrzega N,Moatamed NA

更新日期：2016-10-22 00:00:00

abstract：BACKGROUND:Malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare entity that was first described by Zambrano et al. in 2003 as "Clear cell sarcoma-like tumor of the gastrointestinal tract". It shares some of the histological features of clear cell sarcoma (CCS) but lacks the immunohistochemical r...

journal_title：Diagnostic pathology

authors： Alyousef MJ,Alratroot JA,ElSharkawy T,Shawarby MA,Al Hamad MA,Hashem TM,Alsayyah A

更新日期：2017-03-20 00:00:00

abstract：:Bronchoalveolar lavage (BAL) is a useful diagnostic tool in interstitial lung diseases (ILD). However, differential cell counts are often non specific and immunocytochemistry is time consuming. Staining of glycoproteins by periodic acid Schiff (PAS) reaction may help in discriminating different forms of ILD. In additi...

journal_title：Diagnostic pathology

authors： Hauber HP,Zabel P

更新日期：2009-04-23 00:00:00

abstract：:Telepathology, the practice of pathology at a long distance, has advanced continuously since 1986. Today, fourth-generation telepathology systems, so-called virtual slide telepathology systems, are being used for education applications. Both conventional and innovative surgical pathology diagnostic services are being ...

journal_title：Diagnostic pathology

authors： Ayad E

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:Transbronchial needle aspiration (TBNA) is a minimally invasive procedure performed to diagnose lymph node (LN) adenopathy. TBNA with and without endobronchial ultrasound (EBUS) guidance has a high diagnostic yield for malignant LN enlargement, but the value for diagnosing benign LN enlargement has been less...

journal_title：Diagnostic pathology

authors： Shen H,Lou L,Chen T,Zou Y,Wang B,Xu Z,Ye Q,Shen H,Li W,Xia Y

更新日期：2020-04-15 00:00:00