HPV vaccines and cancer prevention, science versus activism.

abstract：:The African Organization for Research and training in Cancer (AORTIC) bases the following position statements on a critical appraisal of the state on cancer research and cancer care in Africa including information on the availability of data on cancer burden, screening and prevention for cancer in Africa, cancer care ...

journal_title：Infectious agents and cancer

authors： Ogunbiyi JO,Stefan DC,Rebbeck TR

更新日期：2016-12-06 00:00:00

abstract：:Poly(ADP-ribose) polymerases (PARPs) comprise of a large family of 17 proteins encoded by various genes which participate in genome maintenance, apoptosis, inflammatory responses and the regulation of gene expression programs. PARP inhibitors, as therapeutic agents, come into play acting on both PARP 1 and PARP 2. The...

journal_title：Infectious agents and cancer

authors： Usmani H,Hussain SA,Sheikh A

更新日期：2013-12-02 00:00:00

abstract：: The eruption of Kaposi sarcoma (KS) and aggressive non-Hodgkin lymphoma (NHL) in young homosexual men in 1981 in the West heralded the onset of the human immunodeficiency virus (HIV) infection epidemic, which remains one of the biggest challenges to global public health and science ever. Because KS and NHL were incre...

journal_title：Infectious agents and cancer

authors： Mbulaiteye SM,Bhatia K,Adebamowo C,Sasco AJ

更新日期：2011-10-17 00:00:00

abstract：BACKGROUND:Recent studies have revealed the positive antiproliferative and cytotoxic effects of antiviral agents in cancer treatment. The real effect of adjuvant antiviral therapy is still controversial due to the lack of studies in biochemical mechanisms. Here, we studied the effect of the antiviral agent acyclovir on...

journal_title：Infectious agents and cancer

authors： Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D

更新日期：2017-03-23 00:00:00

abstract：BACKGROUND:Human Papillomavirus (HPV) detection results comparing paraffin embedded cervical tissue and other cervical specimens have been done with varying degrees of agreement. However, studies comparing freshly frozen specimens and paraffin embedded specimens of invasive cervical carcinomas are lacking. The aim of t...

journal_title：Infectious agents and cancer

authors： Odida M,de Sanjose S,Sandin S,Quiros B,Alemany L,Lloveras B,Quint W,Kleter B,Alejo M,van Doorn LJ,Weiderpass E

更新日期：2010-09-16 00:00:00

abstract：BACKGROUND:A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined. The aim of this study was to analyze the presence and functionality of human papillomavirus (HPV) and polyomaviruses (BKPyV and JCPyV) in prostate carcinomas in Chilean patie...

journal_title：Infectious agents and cancer

authors： Rodríguez H,Levican J,Muñoz JP,Carrillo D,Acevedo ML,Gaggero A,León O,Gheit T,Espinoza-Navarro O,Castillo J,Gallegos I,Tommasino M,Aguayo F

更新日期：2015-09-01 00:00:00

abstract：:We carried out a retrospective study on the prevalence of HPV and genotype distribution by nested PCR and nucleotide sequencing analysis, in formalin-fixed, paraffin-embedded biopsies of 135 head and neck cancers (HNC) and 29 cervical cancers received between 2009 and 2017 for diagnosis at the Laboratoire National de ...

journal_title：Infectious agents and cancer

authors： Kofi B,Mossoro-Kpinde CD,Mboumba Bouassa RS,Péré H,Robin L,Gresenguet G,Bélec L

更新日期：2019-04-08 00:00:00

abstract：:A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies ...

journal_title：Infectious agents and cancer

authors： Lin F,Zeng A,Yang N,Lin H,Yang E,Wang S,Pintel D,Qiu J

更新日期：2007-01-31 00:00:00

abstract：BACKGROUND:It has been hypothesized that human cytomegalovirus (HCMV) may be associated with breast cancer progression. However, the role of HCMV infection in breast cancer remains controversial. We aimed to assess whether HCMV genes (UL122 and UL83) could be detected in breast carcinomas and reinvestigated their possi...

journal_title：Infectious agents and cancer

authors： Utrera-Barillas D,Valdez-Salazar HA,Gómez-Rangel D,Alvarado-Cabrero I,Aguilera P,Gómez-Delgado A,Ruiz-Tachiquin ME

更新日期：2013-04-04 00:00:00

abstract：BACKGROUND:Lymphoma is highly associated with HIV in sub-Saharan Africa (SSA), which contributes to worse outcomes relative to resource-rich settings, and frequent failure of first-line chemotherapy. However, there are no second-line treatment descriptions for adults with relapsed or refractory lymphoma (RRL) in SSA. ...

journal_title：Infectious agents and cancer

authors： Kaimila B,van der Gronde T,Stanley C,Kasonkanji E,Chikasema M,Tewete B,Fox P,Gopal S

更新日期：2017-08-09 00:00:00

abstract：BACKGROUND:We have previously reported the case of an immunocompetent female patient with a primary cutaneous CD30+ anaplastic large-cell lymphoma (PCALCL) located on her upper right eyelid characterized by the presence of a concurrent active infection by C. pneumoniae and Human herpesvirus 8 (HHV8). This finding sugge...

journal_title：Infectious agents and cancer

authors： Caselli E,Borghi A,Maritati M,Gafà R,Lanza G,Di Luca D,Virgili A,Contini C

更新日期：2016-07-05 00:00:00

abstract：Background:The aims of this study were to evaluate whether HPV infection has a prognostic role in patients with esophageal squamous cell carcinoma who underwent oncological treatment and also to compare the heat shock proteins (Hsp) 90, 27 and 16.2 and growth hormone-releasing hormone receptor (GHRH-R) expression patte...

journal_title：Infectious agents and cancer

authors： Bognár L,Hegedűs I,Bellyei S,Pozsgai É,Zoltán L,Gombos K,Horváth ÖP,Vereczkei A,Papp A

更新日期：2018-11-29 00:00:00

abstract：BACKGROUND:MDM2 gene polymorphisms 285G/C and 344 T/A are two single nucleotide polymorphisms (SNPs) recently identified as important variants that could influence the expression of MDM2 gene through the modulation of transcription factors binding on the SNP309T/G. The 285C variant seems to present a geographically dis...

journal_title：Infectious agents and cancer

authors： Rebbani K,Ezzikouri S,Marchio A,Kandil M,Pineau P,Benjelloun S

更新日期：2014-04-07 00:00:00

abstract：Background:Cervical cancer is a common cancer among women worldwide and is closely related to high-risk human papillomavirus infection (HR-HPV). The immune microenvironment is thought to play an essential role in viral infection and cancer development; however, this relationship remains controversial. Cytokines are an ...

journal_title：Infectious agents and cancer

authors： Li B,Zhang L,Zhao J,Tan G,Zhang W,Zhang N,Tian J,Qu P

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease could play a role in ovarian carcinogenesis. AIM:To review the literature on studies examining the association between ovarian cancer and bacterial or ...

journal_title：Infectious agents and cancer

authors： Ingerslev K,Hogdall E,Schnack TH,Skovrider-Ruminski W,Hogdall C,Blaakaer J

更新日期：2017-05-18 00:00:00

abstract：:Among the DNA tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus (KSHV), account for a considerable percentage of virus-associated cancers. Deregulation of transcription factors signaling pathways is one of the most significant oncogenic characteristics of EBV and KSHV. NF-κB is a transcription fact...

journal_title：Infectious agents and cancer

authors： Charostad J,Nakhaie M,Dehghani A,Faghihloo E

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVE:The aim of this study was to screen for the presence of Epstein Barr Virus (EBV) among Sudanese patients with Nasopharyngeal Carcinoma (NPC). METHODS:In this study, 150 tissue samples that were previously diagnosed as having NPC were screened for the presence of EBV using Polymerase Chain Reaction (PCR). PCR...

journal_title：Infectious agents and cancer

authors： Ahmed HG,Suliman RS,El Aziz MS,Alshammari FD

更新日期：2015-02-17 00:00:00

abstract：BACKGROUND:Cervical cancer is the fourth most common cancer in women worldwide with highest incidence reported in Eastern Africa in 2012. The primary goal of this study was to study the expression of p16INK4a in squamous cell carcinoma (SCC) of the cervix by immunohistochemistry (IHC) and determine relation with clinic...

journal_title：Infectious agents and cancer

authors： Sarwath H,Bansal D,Husain NE,Mohamed M,Sultan AA,Bedri S

更新日期：2017-09-30 00:00:00

abstract：:Bcr-Abl plays a central role in the development of chromosome positive leukaemia. Chronic Myeloid leukaemia occurs due to increase proliferation and resistance to apoptosis by Bcr-Abl positive cells. Imatinib (STI571) is the first drug in the family of Bcr-Abl tyrosine kinase inhibitors while Nilotinib (AMN107) and Da...

journal_title：Infectious agents and cancer

authors： Mughal A,Aslam HM,Khan AM,Saleem S,Umah R,Saleem M

更新日期：2013-06-20 00:00:00

abstract：BACKGROUND:Cervical cancer is the major cause of morbidity and mortality in Thai women. Nevertheless, the preventive strategy such as HPV vaccination program has not been implemented at the national level. This study explored the HPV prevalence and genotypic distribution in a large cohort of Thai women. METHODS:A hosp...

journal_title：Infectious agents and cancer

authors： Kantathavorn N,Mahidol C,Sritana N,Sricharunrat T,Phoolcharoen N,Auewarakul C,Teerayathanakul N,Taepisitpong C,Saeloo S,Sornsamdang G,Udomchaiprasertkul W,Krongthong W,Arnamwong A

更新日期：2015-03-02 00:00:00

abstract：Background:High risk human papillomaviruses (HPVs) have been unequivocally recognised as the necessary cause of squamous intraepithelial lesions (SIL) and invasive carcinoma of the cervix. The distribution and the role of unclassified risk HPV genotypes in cervical neoplasia has not been fully elucidated. Methods:Liqu...

journal_title：Infectious agents and cancer

authors： Annunziata C,Stellato G,Greggi S,Sanna V,Curcio MP,Losito S,Botti G,Buonaguro L,Buonaguro FM,Tornesello ML

更新日期：2018-07-24 00:00:00

abstract：Background:The detection of the Epstein-Barr capsid antigen (VCA) immunoglobulin A (IgA) is widely used in the diagnosis of nasopharyngeal carcinoma (NPC), but a reference standard for evaluating the presence of VCA-IgA is not yet available. Therefore, a reference standard is urgently needed for a uniform and quantitat...

journal_title：Infectious agents and cancer

authors： Chen H,Zhong Q,Wu X,Ding Y,Chen Q,Xue N,Xu Y,Chen S

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:The human immunodeficiency virus type 1 (HIV-1) regulatory protein, Nef, is an attractive vaccine target because it is involved in viral pathogenesis, is expressed early in the viral life cycle and harbors many T and B cell epitopes. Several clinical trials include gene-based vaccines encoding this protein. ...

journal_title：Infectious agents and cancer

authors： Bråve A,Gudmundsdotter L,Gasteiger G,Hallermalm K,Kastenmuller W,Rollman E,Boberg A,Engström G,Reiland S,Cosma A,Drexler I,Hinkula J,Wahren B,Erfle V

更新日期：2007-07-10 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major public health burden in Europe, causing an increasing level of liver-related morbidity and mortality, characterized by several regional variations in the genotypes distribution. A comprehensive review of the literature from 2000 to 2015 was used to gather country-specific d...

journal_title：Infectious agents and cancer

authors： Petruzziello A,Marigliano S,Loquercio G,Cacciapuoti C

更新日期：2016-10-12 00:00:00

abstract：UNLABELLED: BACKGROUND:Liver disease is the second cause of death among HIV patients receiving highly active antiretroviral therapy (HAART) in Europe. HIV patients have a high prevalence of chronic HBV (6-10%) and HCV (33%) co-infection, and accelerated progression of viral hepatitis. Furthermore, the long duration of...

journal_title：Infectious agents and cancer

authors： De Nardo P,Viscione M,Corpolongo A,Bellagamba R,Vennarecci G,Ettorre GM,Gentilotti E,Tommasi C,Nicastri E

更新日期：2012-06-28 00:00:00

abstract：BACKGROUND:With successful antiretroviral therapy, non-communicable diseases, including malignancies, are increasingly contributing to morbidity and mortality among HIV-infected persons. The epidemiology of AIDS-defining cancers (ADCs) and non-AIDS-defining cancers (NADCs) in HIV-infected populations in Brazil has not ...

journal_title：Infectious agents and cancer

authors： Castilho JL,Luz PM,Shepherd BE,Turner M,Ribeiro SR,Bebawy SS,Netto JS,McGowan CC,Veloso VG,Engels EA,Sterling TR,Grinsztejn B

更新日期：2015-02-02 00:00:00

abstract：: Seroepidemiological surveys show that the prevalence of human herpesvirus 8 (HHV-8) infection mostly varies in various geographical areas and reflects the local incidence of classic and endemic KS, being widespread in sub-Saharan Africa and Mediterranean countries and uncommon in the USA and Northern Europe. In the M...

journal_title：Infectious agents and cancer

authors： Jalilvand S,Shoja Z,Mokhtari-Azad T,Nategh R,Gharehbaghian A

更新日期：2011-04-28 00:00:00

abstract：Background:Platelet-rich-plasma (PRP) is largely used, thanks to its properties, as wound therapy after surgical resection. Several studies and clinical findings have demonstrated that the PRP can accelerate the regeneration and the repair of tissues through the action of the platelet-derived growth factors. Material ...

journal_title：Infectious agents and cancer

authors： Barbieri A,Bimonte S,Loquercio G,Rea D,Cascella M,Anniciello A,Luciano A,Palma G,Di Costanzo G,Rosa A,Giuliano P,Arra C

更新日期：2019-08-28 00:00:00

abstract：BACKGROUND:Killian polyp (KP) is a benign lesion that arises from the maxillary sinus. The etiology of KP is unknown. The aim of this study was to investigate the potential involvement of human papilloma- (HPV) and polyoma-viruses (HPyV) infections in the onset of KP. METHODS:DNA from antral (n = 14) and nasal (n = 14...

journal_title：Infectious agents and cancer

authors： Oton-Gonzalez L,Rotondo JC,Cerritelli L,Malagutti N,Lanzillotti C,Bononi I,Ciorba A,Bianchini C,Mazziotta C,De Mattei M,Pelucchi S,Tognon M,Martini F

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:Burkitt lymphoma is an aggressive B-cell lymphoma presenting in three clinical forms: endemic, sporadic and immunodeficiency-associated. More than 90% of endemic Burkitt lymphoma carry latent Epstein-Barr virus, whereas only 20% of sporadic Burkitt lymphoma are associated with Epstein-Barr infection. Althoug...

journal_title：Infectious agents and cancer

authors： Ambrosio MR,Navari M,Di Lisio L,Leon EA,Onnis A,Gazaneo S,Mundo L,Ulivieri C,Gomez G,Lazzi S,Piris MA,Leoncini L,De Falco G

更新日期：2014-04-14 00:00:00