Is human cytomegalovirus associated with breast cancer progression?

abstract：OBJECTIVES:To evaluate the prevalence of human papillomavirus (HPV) types, and risk factors for HPV positivity across cervix, vagina and anus, we conducted a study among 138 women with human immunodeficiency virus (HIV). GOAL:Compare the prevalence of different HPV types and the risk factors for HPV positivity in thre...

journal_title：Infectious agents and cancer

authors： Gonçalves MA,Randi G,Arslan A,Villa LL,Burattini MN,Franceschi S,Donadi EA,Massad E

更新日期：2008-03-14 00:00:00

abstract：BACKGROUND:MDM2 gene polymorphisms 285G/C and 344 T/A are two single nucleotide polymorphisms (SNPs) recently identified as important variants that could influence the expression of MDM2 gene through the modulation of transcription factors binding on the SNP309T/G. The 285C variant seems to present a geographically dis...

journal_title：Infectious agents and cancer

authors： Rebbani K,Ezzikouri S,Marchio A,Kandil M,Pineau P,Benjelloun S

更新日期：2014-04-07 00:00:00

abstract：Background:Hepatitis C virus (HCV) represents a major risk factor for hepatocellular carcinoma (HCC) development and anti-HCV therapy is a significant measure to reduce the incidence of HCC, however development of HCC in HCV treated patients is an emerging clinical problem which needs to be investigated. In this study ...

journal_title：Infectious agents and cancer

authors： Khalid J,Umar M,Ur-Rehman T,Ali M,Khan GM

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:The MDM2 gene is the major negative regulator of p53, a tumor suppressor protein. Single nucleotide polymorphism in promoter region of MDM2 gene leads to increased expression resulting in higher levels of MDM2 protein. This event increases the attenuation of the p53 pathway. Polymorphisms in this gene can in...

journal_title：Infectious agents and cancer

authors： Amaral CM,Cetkovská K,Gurgel AP,Cardoso MV,Chagas BS,Paiva Júnior SS,de Lima Rde C,Silva-Neto JC,Silva LA,Muniz MT,Balbino VQ,Freitas AC

更新日期：2014-07-18 00:00:00

abstract：:Meat is a crucial nutrient for human health since it represents a giant supply of proteins, minerals, and vitamins. On the opposite hand, the intake of red and processed meat is taken into account dangerous due to its potential of carcinogenesis and cancer risk improvement, particularly for colorectal cancer (CRC), al...

journal_title：Infectious agents and cancer

authors： Cascella M,Bimonte S,Barbieri A,Del Vecchio V,Caliendo D,Schiavone V,Fusco R,Granata V,Arra C,Cuomo A

更新日期：2018-01-15 00:00:00

abstract：Background:Platelet-rich-plasma (PRP) is largely used, thanks to its properties, as wound therapy after surgical resection. Several studies and clinical findings have demonstrated that the PRP can accelerate the regeneration and the repair of tissues through the action of the platelet-derived growth factors. Material ...

journal_title：Infectious agents and cancer

authors： Barbieri A,Bimonte S,Loquercio G,Rea D,Cascella M,Anniciello A,Luciano A,Palma G,Di Costanzo G,Rosa A,Giuliano P,Arra C

更新日期：2019-08-28 00:00:00

abstract：BACKGROUND:The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease could play a role in ovarian carcinogenesis. AIM:To review the literature on studies examining the association between ovarian cancer and bacterial or ...

journal_title：Infectious agents and cancer

authors： Ingerslev K,Hogdall E,Schnack TH,Skovrider-Ruminski W,Hogdall C,Blaakaer J

更新日期：2017-05-18 00:00:00

abstract：Background:High risk human papillomaviruses (HPVs) have been unequivocally recognised as the necessary cause of squamous intraepithelial lesions (SIL) and invasive carcinoma of the cervix. The distribution and the role of unclassified risk HPV genotypes in cervical neoplasia has not been fully elucidated. Methods:Liqu...

journal_title：Infectious agents and cancer

authors： Annunziata C,Stellato G,Greggi S,Sanna V,Curcio MP,Losito S,Botti G,Buonaguro L,Buonaguro FM,Tornesello ML

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:Cervical cancer is the fourth most common cancer in women worldwide with highest incidence reported in Eastern Africa in 2012. The primary goal of this study was to study the expression of p16INK4a in squamous cell carcinoma (SCC) of the cervix by immunohistochemistry (IHC) and determine relation with clinic...

journal_title：Infectious agents and cancer

authors： Sarwath H,Bansal D,Husain NE,Mohamed M,Sultan AA,Bedri S

更新日期：2017-09-30 00:00:00

abstract：:The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses,...

journal_title：Infectious agents and cancer

authors： Alibek K,Mussabekova A,Kakpenova A,Duisembekova A,Baiken Y,Aituov B,Karatayeva N,Zhussupbekova S

更新日期：2013-12-10 00:00:00

abstract：BACKGROUND:Kaposi sarcoma (KS) is the most common AIDS-defining tumour in HIV-infected individuals in Africa. Kaposi sarcoma herpes virus (KSHV) infection precedes development of KS. KSHV co-infection may be associated with worse outcomes in HIV disease and elevated KSHV viral load may be an early marker for advanced H...

journal_title：Infectious agents and cancer

authors： Maskew M,Macphail AP,Whitby D,Egger M,Wallis CL,Fox MP

更新日期：2011-11-17 00:00:00

abstract：:Among the DNA tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus (KSHV), account for a considerable percentage of virus-associated cancers. Deregulation of transcription factors signaling pathways is one of the most significant oncogenic characteristics of EBV and KSHV. NF-κB is a transcription fact...

journal_title：Infectious agents and cancer

authors： Charostad J,Nakhaie M,Dehghani A,Faghihloo E

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract and is the third leading cause of cancer death worldwide. Epstein-Barr virus (EBV) has been associated with approximately 10% of the total cases of gastric carcinomas. No previous study has analyzed the prevalence of EBV in...

journal_title：Infectious agents and cancer

authors： Nogueira C,Mota M,Gradiz R,Cipriano MA,Caramelo F,Cruz H,Alarcão A,E Sousa FC,Oliveira F,Martinho F,Pereira JM,Figueiredo P,Leitão M

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:Recent studies have revealed the positive antiproliferative and cytotoxic effects of antiviral agents in cancer treatment. The real effect of adjuvant antiviral therapy is still controversial due to the lack of studies in biochemical mechanisms. Here, we studied the effect of the antiviral agent acyclovir on...

journal_title：Infectious agents and cancer

authors： Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D

更新日期：2017-03-23 00:00:00

abstract：:Poly(ADP-ribose) polymerases (PARPs) comprise of a large family of 17 proteins encoded by various genes which participate in genome maintenance, apoptosis, inflammatory responses and the regulation of gene expression programs. PARP inhibitors, as therapeutic agents, come into play acting on both PARP 1 and PARP 2. The...

journal_title：Infectious agents and cancer

authors： Usmani H,Hussain SA,Sheikh A

更新日期：2013-12-02 00:00:00

abstract：Background:Invasive cervical cancer (ICC) is more prevalent in HIV infected women and occurs at younger median age than in HIV negative women. Organized cervical cancer screening (CCS) is presently lacking in Nigeria, and the age at CCS is not known in this population. We sought to examine the age at CCS, the cytology ...

journal_title：Infectious agents and cancer

authors： Musa J,Achenbach CJ,Evans CT,Jordan N,Daru PH,Silas O,Sagay AS,Anorlu R,Mehta SD,Wehbe F,Simon MA,Adewole IF,Hou L,Murphy RL

更新日期：2019-11-29 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major public health burden in Europe, causing an increasing level of liver-related morbidity and mortality, characterized by several regional variations in the genotypes distribution. A comprehensive review of the literature from 2000 to 2015 was used to gather country-specific d...

journal_title：Infectious agents and cancer

authors： Petruzziello A,Marigliano S,Loquercio G,Cacciapuoti C

更新日期：2016-10-12 00:00:00

abstract：:The evolutionarily novel genes originated through different molecular mechanisms are expressed in tumors. Sometimes the expression of evolutionarily novel genes in tumors is highly specific. Moreover positive selection of many human tumor-related genes in primate lineage suggests their involvement in the origin of new...

journal_title：Infectious agents and cancer

authors： Kozlov AP

更新日期：2016-07-19 00:00:00

abstract：:This is a summary of the 1st Academic Model Providing Access to Healthcare (AMPATH) Oncology Institute research grant writing workshop organized in collaboration with the Kenya Medical Research Institute (KEMRI) and held in Kisumu, Kenya from January 16th to 18th, 2013. The goal of this meeting was to mentor future Ke...

journal_title：Infectious agents and cancer

authors： Moormann A,Skiles J,Koros E,Asirwa FC,Busakhala N,Loehrer P

更新日期：2013-10-07 00:00:00

abstract：:In 2012, Infectious Agents and Cancer commissioned a thematic series collection of articles on Prevention of HPV related cancer. The articles have attracted wide interest and stimulated debate, including about the utility of vaccines in cancer control. The application of vaccines to cancer control fulfills a promise e...

journal_title：Infectious agents and cancer

authors： Mbulaiteye SM,Buonaguro FM

更新日期：2013-05-04 00:00:00

abstract：BACKGROUND:To clarify the immunological alterations leading to classical Kaposi sarcoma (cKS) among people infected with KS-associated herpesvirus (KSHV). METHODS:In a population-based study of 119 cKS cases, 105 KSHV-seropositive controls, and 155 KSHV-seronegative controls, we quantified plasma soluble cluster of di...

journal_title：Infectious agents and cancer

authors： Pelser C,Middeldorp J,Mbulaiteye SM,Lauria C,Messina A,Viviano E,Romano N,Vitale F,Goedert JJ

更新日期：2010-10-12 00:00:00

abstract：:Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HI...

journal_title：Infectious agents and cancer

authors： Zuze T,Painschab MS,Seguin R,Kudowa E,Kaimila B,Kasonkanji E,Tomoka T,Dhungel BM,Mulenga M,Chikasema M,Tewete B,Ntangwanika A,Chiyoyola S,Chimzimu F,Kampani C,Krysiak R,Montgomery ND,Fedoriw Y,Gopal S

更新日期：2018-06-28 00:00:00

abstract：BACKGROUND:We have previously reported the case of an immunocompetent female patient with a primary cutaneous CD30+ anaplastic large-cell lymphoma (PCALCL) located on her upper right eyelid characterized by the presence of a concurrent active infection by C. pneumoniae and Human herpesvirus 8 (HHV8). This finding sugge...

journal_title：Infectious agents and cancer

authors： Caselli E,Borghi A,Maritati M,Gafà R,Lanza G,Di Luca D,Virgili A,Contini C

更新日期：2016-07-05 00:00:00

abstract：: The eruption of Kaposi sarcoma (KS) and aggressive non-Hodgkin lymphoma (NHL) in young homosexual men in 1981 in the West heralded the onset of the human immunodeficiency virus (HIV) infection epidemic, which remains one of the biggest challenges to global public health and science ever. Because KS and NHL were incre...

journal_title：Infectious agents and cancer

authors： Mbulaiteye SM,Bhatia K,Adebamowo C,Sasco AJ

更新日期：2011-10-17 00:00:00

abstract：BACKGROUND:Most malignant lymphomas in HIV-patients are caused by reactivation of EBV-infection. Some lymphomas have a very rapid fulminant course. HHV-8 has also been reported to be a cause of lymphoma. The role of CMV in the development of lymphoma is not clear, though both CMV and HHV-8 have been reported in tissues...

journal_title：Infectious agents and cancer

authors： Grützmeier S,Porwit A,Schmitt C,Sandström E,Åkerlund B,Ernberg I

更新日期：2016-08-22 00:00:00

abstract：Background:Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the targeting specificity of E7 methyla...

journal_title：Infectious agents and cancer

authors： Na Rangsee N,Yanatatsaneejit P,Pisitkun T,Somparn P,Jintaridth P,Topanurak S

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Human papillomavirus type 16 (HPV-16) infection is an important cause of cervical cancer, other anogenital cancers and, possibly, some oral and pharyngeal cancers. The association of HPV-16 with oesophageal and with prostate cancers has not been firmly established. METHODS:We analysed sera from 3,757 HIV se...

journal_title：Infectious agents and cancer

authors： Sitas F,Urban M,Stein L,Beral V,Ruff P,Hale M,Patel M,O'Connell D,Yu XQ,Verzijden A,Marais D,Williamson AL

更新日期：2007-03-02 00:00:00

abstract：BACKGROUND:Cervical cancer is one of the most common tumors affecting women with a disproportionate mortality occurring in developing countries. Despite the high prevalence of cervical cancer and cervical neoplasia in Gabon, few studies have been performed to evaluate the prevalence and determinants of HPV infection in...

journal_title：Infectious agents and cancer

authors： Zoa Assoumou S,Ndjoyi Mbiguino A,Mabika Mabika B,Nguizi Ogoula S,El Mzibri M,Khattabi A,Ennaji MM

更新日期：2016-01-15 00:00:00

abstract：Background:Tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are recommended as the first-line choices regarding the treatment of chronic hepatits B. The impact of the two antiviral agents on prognosis of Chronic hepatitis B (CHB) related hepatocellular carcinoma (HCC) remains to be explored. We aim to investigat...

journal_title：Infectious agents and cancer

authors： Zhang M,Wang D,Liu H,Li H

更新日期：2018-06-08 00:00:00

abstract：:Thymoquinone (TQ) is the principal active monomer isolated from the seed of the medicinal plant Nigella sativa. This compound has antitumor effects against various types of cancer including hepatocellular carcinoma (HCC), mainly due to its anti-inflammatory and anti-oxidant properties. Several pre-clinical studies sho...

journal_title：Infectious agents and cancer

authors： Bimonte S,Albino V,Barbieri A,Tamma ML,Nasto A,Palaia R,Molino C,Bianco P,Vitale A,Schiano R,Giudice A,Cascella M

更新日期：2019-04-16 00:00:00