Expression of evolutionarily novel genes in tumors.

abstract：BACKGROUND:Langerhans cell (LC) sarcoma (LCS) is a high-grade neoplasm with overtly malignant cytologic features and an LC phenotype. We very recently suggested that LC behaves as a reservoir for common dermotropic Merkel cell polyomavirus (MCPyV) and determined the relationship between LC histiocytosis (LCH), which ha...

journal_title：Infectious agents and cancer

authors： Murakami I,Matsushita M,Iwasaki T,Kuwamoto S,Kato M,Horie Y,Hayashi K,Gogusev J,Jaubert F,Nakamoto S,Yamakawa M,Nakamine H,Takata K,Oka T,Yoshino T

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:Human Papillomavirus (HPV) detection results comparing paraffin embedded cervical tissue and other cervical specimens have been done with varying degrees of agreement. However, studies comparing freshly frozen specimens and paraffin embedded specimens of invasive cervical carcinomas are lacking. The aim of t...

journal_title：Infectious agents and cancer

authors： Odida M,de Sanjose S,Sandin S,Quiros B,Alemany L,Lloveras B,Quint W,Kleter B,Alejo M,van Doorn LJ,Weiderpass E

更新日期：2010-09-16 00:00:00

abstract：BACKGROUND:We have previously reported the case of an immunocompetent female patient with a primary cutaneous CD30+ anaplastic large-cell lymphoma (PCALCL) located on her upper right eyelid characterized by the presence of a concurrent active infection by C. pneumoniae and Human herpesvirus 8 (HHV8). This finding sugge...

journal_title：Infectious agents and cancer

authors： Caselli E,Borghi A,Maritati M,Gafà R,Lanza G,Di Luca D,Virgili A,Contini C

更新日期：2016-07-05 00:00:00

abstract：BACKGROUND:The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease could play a role in ovarian carcinogenesis. AIM:To review the literature on studies examining the association between ovarian cancer and bacterial or ...

journal_title：Infectious agents and cancer

authors： Ingerslev K,Hogdall E,Schnack TH,Skovrider-Ruminski W,Hogdall C,Blaakaer J

更新日期：2017-05-18 00:00:00

abstract：Background:The detection of the Epstein-Barr capsid antigen (VCA) immunoglobulin A (IgA) is widely used in the diagnosis of nasopharyngeal carcinoma (NPC), but a reference standard for evaluating the presence of VCA-IgA is not yet available. Therefore, a reference standard is urgently needed for a uniform and quantitat...

journal_title：Infectious agents and cancer

authors： Chen H,Zhong Q,Wu X,Ding Y,Chen Q,Xue N,Xu Y,Chen S

更新日期：2020-04-29 00:00:00

abstract：:Helicobacter pylori is an important yet unproven etiological agent of gastric cancer. H. pylori infection is more prevalent in developing Asian countries like India and it is usually acquired at an early age. It has been two decades since Marshall and Warren (1984) first described curved bacilli in the stomach of ulce...

journal_title：Infectious agents and cancer

authors： Akhter Y,Ahmed I,Devi SM,Ahmed N

更新日期：2007-01-04 00:00:00

abstract：BACKGROUND:A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined. The aim of this study was to analyze the presence and functionality of human papillomavirus (HPV) and polyomaviruses (BKPyV and JCPyV) in prostate carcinomas in Chilean patie...

journal_title：Infectious agents and cancer

authors： Rodríguez H,Levican J,Muñoz JP,Carrillo D,Acevedo ML,Gaggero A,León O,Gheit T,Espinoza-Navarro O,Castillo J,Gallegos I,Tommasino M,Aguayo F

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Infection with human papillomavirus (HPV) is associated with uterine cervical intraepithelial neoplasia (CIN) and invasive cancers (ICC). Approximately 80% of ICC cases are diagnosed in under-developed countries. Vaccine development relies on knowledge of HPV genotypes characteristic of LSIL, HSIL and cancer...

journal_title：Infectious agents and cancer

authors： Vidal AC,Murphy SK,Hernandez BY,Vasquez B,Bartlett JA,Oneko O,Mlay P,Obure J,Overcash F,Smith JS,van der Kolk M,Hoyo C

更新日期：2011-11-14 00:00:00

abstract：BACKGROUND:With successful antiretroviral therapy, non-communicable diseases, including malignancies, are increasingly contributing to morbidity and mortality among HIV-infected persons. The epidemiology of AIDS-defining cancers (ADCs) and non-AIDS-defining cancers (NADCs) in HIV-infected populations in Brazil has not ...

journal_title：Infectious agents and cancer

authors： Castilho JL,Luz PM,Shepherd BE,Turner M,Ribeiro SR,Bebawy SS,Netto JS,McGowan CC,Veloso VG,Engels EA,Sterling TR,Grinsztejn B

更新日期：2015-02-02 00:00:00

abstract：:Bcr-Abl plays a central role in the development of chromosome positive leukaemia. Chronic Myeloid leukaemia occurs due to increase proliferation and resistance to apoptosis by Bcr-Abl positive cells. Imatinib (STI571) is the first drug in the family of Bcr-Abl tyrosine kinase inhibitors while Nilotinib (AMN107) and Da...

journal_title：Infectious agents and cancer

authors： Mughal A,Aslam HM,Khan AM,Saleem S,Umah R,Saleem M

更新日期：2013-06-20 00:00:00

abstract：:Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of these viruses have been found in human tumors, suggesting an etiological relationship with cancer. In particular,...

journal_title：Infectious agents and cancer

authors： Levican J,Acevedo M,León O,Gaggero A,Aguayo F

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:It has been hypothesized that human cytomegalovirus (HCMV) may be associated with breast cancer progression. However, the role of HCMV infection in breast cancer remains controversial. We aimed to assess whether HCMV genes (UL122 and UL83) could be detected in breast carcinomas and reinvestigated their possi...

journal_title：Infectious agents and cancer

authors： Utrera-Barillas D,Valdez-Salazar HA,Gómez-Rangel D,Alvarado-Cabrero I,Aguilera P,Gómez-Delgado A,Ruiz-Tachiquin ME

更新日期：2013-04-04 00:00:00

abstract：Background:Platelet-rich-plasma (PRP) is largely used, thanks to its properties, as wound therapy after surgical resection. Several studies and clinical findings have demonstrated that the PRP can accelerate the regeneration and the repair of tissues through the action of the platelet-derived growth factors. Material ...

journal_title：Infectious agents and cancer

authors： Barbieri A,Bimonte S,Loquercio G,Rea D,Cascella M,Anniciello A,Luciano A,Palma G,Di Costanzo G,Rosa A,Giuliano P,Arra C

更新日期：2019-08-28 00:00:00

abstract：BACKGROUND:Morbidity and mortality data highlight prostate cancer as the most commonly diagnosed neoplasm in Jamaican males. This report examines the association between dietary patterns and risk of prostate cancer in Jamaican men. MATERIALS AND METHODS:Case-control study of 204 histologically confirmed newly diagnose...

journal_title：Infectious agents and cancer

authors： Jackson M,Walker S,Simpson C,McFarlane-Anderson N,Bennett F

更新日期：2009-02-10 00:00:00

abstract：:Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HI...

journal_title：Infectious agents and cancer

authors： Zuze T,Painschab MS,Seguin R,Kudowa E,Kaimila B,Kasonkanji E,Tomoka T,Dhungel BM,Mulenga M,Chikasema M,Tewete B,Ntangwanika A,Chiyoyola S,Chimzimu F,Kampani C,Krysiak R,Montgomery ND,Fedoriw Y,Gopal S

更新日期：2018-06-28 00:00:00

abstract：Background:High risk human papillomaviruses (HPVs) have been unequivocally recognised as the necessary cause of squamous intraepithelial lesions (SIL) and invasive carcinoma of the cervix. The distribution and the role of unclassified risk HPV genotypes in cervical neoplasia has not been fully elucidated. Methods:Liqu...

journal_title：Infectious agents and cancer

authors： Annunziata C,Stellato G,Greggi S,Sanna V,Curcio MP,Losito S,Botti G,Buonaguro L,Buonaguro FM,Tornesello ML

更新日期：2018-07-24 00:00:00

abstract：:Thymoquinone (TQ) is the principal active monomer isolated from the seed of the medicinal plant Nigella sativa. This compound has antitumor effects against various types of cancer including hepatocellular carcinoma (HCC), mainly due to its anti-inflammatory and anti-oxidant properties. Several pre-clinical studies sho...

journal_title：Infectious agents and cancer

authors： Bimonte S,Albino V,Barbieri A,Tamma ML,Nasto A,Palaia R,Molino C,Bianco P,Vitale A,Schiano R,Giudice A,Cascella M

更新日期：2019-04-16 00:00:00

abstract：BACKGROUND:The MDM2 gene is the major negative regulator of p53, a tumor suppressor protein. Single nucleotide polymorphism in promoter region of MDM2 gene leads to increased expression resulting in higher levels of MDM2 protein. This event increases the attenuation of the p53 pathway. Polymorphisms in this gene can in...

journal_title：Infectious agents and cancer

authors： Amaral CM,Cetkovská K,Gurgel AP,Cardoso MV,Chagas BS,Paiva Júnior SS,de Lima Rde C,Silva-Neto JC,Silva LA,Muniz MT,Balbino VQ,Freitas AC

更新日期：2014-07-18 00:00:00

abstract：BACKGROUND:The human papilloma viruses (HPVs) are DNA viruses associated with benign and malignant lesions of skin and mucous membranes. The HPVs has been implicated as the cause of virtually all cervical cancers worldwide but studies showed that these viruses can cause numerous cancers in several tissues including Ora...

journal_title：Infectious agents and cancer

authors： Visalli G,Currò M,Facciolà A,Riso R,Mondello P,Laganà P,Di Pietro A,Picerno I,Spataro P

更新日期：2016-08-26 00:00:00

abstract：Background:The Instituto Angolano de Controlo do Cancer (IACC) Cancer Registry in Luanda, Angola is the most ancient and organized hospital-based cancer registry in Angola and provides data on cancer cases treated in several hospital facilities in Luanda. Methods:Newly-diagnosed cancer cases (2012-2016) of IACC were c...

journal_title：Infectious agents and cancer

authors： Miguel F,Bento MJ,de Lacerda GF,Weiderpass E,Santos LL

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:Sexually transmitted infections (STIs) are hypothesized to play a role in the development of prostate cancer, perhaps due to inflammation-induced oncogenesis. We assessed in a nationally representative population of middle-aged men whether sexual behavior indicators for an increased risk of genital infection...

journal_title：Infectious agents and cancer

authors： Werny DM,Saraiya M,Chen X,Platz EA

更新日期：2007-10-24 00:00:00

abstract：Background:Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the targeting specificity of E7 methyla...

journal_title：Infectious agents and cancer

authors： Na Rangsee N,Yanatatsaneejit P,Pisitkun T,Somparn P,Jintaridth P,Topanurak S

更新日期：2020-02-03 00:00:00

abstract：:Poly(ADP-ribose) polymerases (PARPs) comprise of a large family of 17 proteins encoded by various genes which participate in genome maintenance, apoptosis, inflammatory responses and the regulation of gene expression programs. PARP inhibitors, as therapeutic agents, come into play acting on both PARP 1 and PARP 2. The...

journal_title：Infectious agents and cancer

authors： Usmani H,Hussain SA,Sheikh A

更新日期：2013-12-02 00:00:00

abstract：:In 2012, Infectious Agents and Cancer commissioned a thematic series collection of articles on Prevention of HPV related cancer. The articles have attracted wide interest and stimulated debate, including about the utility of vaccines in cancer control. The application of vaccines to cancer control fulfills a promise e...

journal_title：Infectious agents and cancer

authors： Mbulaiteye SM,Buonaguro FM

更新日期：2013-05-04 00:00:00

abstract：BACKGROUND:Burkitt lymphoma is an aggressive B-cell lymphoma presenting in three clinical forms: endemic, sporadic and immunodeficiency-associated. More than 90% of endemic Burkitt lymphoma carry latent Epstein-Barr virus, whereas only 20% of sporadic Burkitt lymphoma are associated with Epstein-Barr infection. Althoug...

journal_title：Infectious agents and cancer

authors： Ambrosio MR,Navari M,Di Lisio L,Leon EA,Onnis A,Gazaneo S,Mundo L,Ulivieri C,Gomez G,Lazzi S,Piris MA,Leoncini L,De Falco G

更新日期：2014-04-14 00:00:00

abstract：: Seroepidemiological surveys show that the prevalence of human herpesvirus 8 (HHV-8) infection mostly varies in various geographical areas and reflects the local incidence of classic and endemic KS, being widespread in sub-Saharan Africa and Mediterranean countries and uncommon in the USA and Northern Europe. In the M...

journal_title：Infectious agents and cancer

authors： Jalilvand S,Shoja Z,Mokhtari-Azad T,Nategh R,Gharehbaghian A

更新日期：2011-04-28 00:00:00

abstract：BACKGROUND:Cervical cancer is the major cause of morbidity and mortality in Thai women. Nevertheless, the preventive strategy such as HPV vaccination program has not been implemented at the national level. This study explored the HPV prevalence and genotypic distribution in a large cohort of Thai women. METHODS:A hosp...

journal_title：Infectious agents and cancer

authors： Kantathavorn N,Mahidol C,Sritana N,Sricharunrat T,Phoolcharoen N,Auewarakul C,Teerayathanakul N,Taepisitpong C,Saeloo S,Sornsamdang G,Udomchaiprasertkul W,Krongthong W,Arnamwong A

更新日期：2015-03-02 00:00:00

abstract：:The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses,...

journal_title：Infectious agents and cancer

authors： Alibek K,Mussabekova A,Kakpenova A,Duisembekova A,Baiken Y,Aituov B,Karatayeva N,Zhussupbekova S

更新日期：2013-12-10 00:00:00

abstract：Background:The aims of this study were to evaluate whether HPV infection has a prognostic role in patients with esophageal squamous cell carcinoma who underwent oncological treatment and also to compare the heat shock proteins (Hsp) 90, 27 and 16.2 and growth hormone-releasing hormone receptor (GHRH-R) expression patte...

journal_title：Infectious agents and cancer

authors： Bognár L,Hegedűs I,Bellyei S,Pozsgai É,Zoltán L,Gombos K,Horváth ÖP,Vereczkei A,Papp A

更新日期：2018-11-29 00:00:00

abstract：Background:Hepatitis C virus (HCV) represents a major risk factor for hepatocellular carcinoma (HCC) development and anti-HCV therapy is a significant measure to reduce the incidence of HCC, however development of HCC in HCV treated patients is an emerging clinical problem which needs to be investigated. In this study ...

journal_title：Infectious agents and cancer

authors： Khalid J,Umar M,Ur-Rehman T,Ali M,Khan GM

更新日期：2020-05-27 00:00:00