The interplay between EBV and KSHV viral products and NF-κB pathway in oncogenesis.

abstract：Background:Cervical cancer is a common cancer among women worldwide and is closely related to high-risk human papillomavirus infection (HR-HPV). The immune microenvironment is thought to play an essential role in viral infection and cancer development; however, this relationship remains controversial. Cytokines are an ...

journal_title：Infectious agents and cancer

authors： Li B,Zhang L,Zhao J,Tan G,Zhang W,Zhang N,Tian J,Qu P

更新日期：2019-06-28 00:00:00

abstract：:This is a summary of the 1st Academic Model Providing Access to Healthcare (AMPATH) Oncology Institute research grant writing workshop organized in collaboration with the Kenya Medical Research Institute (KEMRI) and held in Kisumu, Kenya from January 16th to 18th, 2013. The goal of this meeting was to mentor future Ke...

journal_title：Infectious agents and cancer

authors： Moormann A,Skiles J,Koros E,Asirwa FC,Busakhala N,Loehrer P

更新日期：2013-10-07 00:00:00

abstract：BACKGROUND:MDM2 gene polymorphisms 285G/C and 344 T/A are two single nucleotide polymorphisms (SNPs) recently identified as important variants that could influence the expression of MDM2 gene through the modulation of transcription factors binding on the SNP309T/G. The 285C variant seems to present a geographically dis...

journal_title：Infectious agents and cancer

authors： Rebbani K,Ezzikouri S,Marchio A,Kandil M,Pineau P,Benjelloun S

更新日期：2014-04-07 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major public health burden in Europe, causing an increasing level of liver-related morbidity and mortality, characterized by several regional variations in the genotypes distribution. A comprehensive review of the literature from 2000 to 2015 was used to gather country-specific d...

journal_title：Infectious agents and cancer

authors： Petruzziello A,Marigliano S,Loquercio G,Cacciapuoti C

更新日期：2016-10-12 00:00:00

abstract：Background:Invasive cervical cancer (ICC) is more prevalent in HIV infected women and occurs at younger median age than in HIV negative women. Organized cervical cancer screening (CCS) is presently lacking in Nigeria, and the age at CCS is not known in this population. We sought to examine the age at CCS, the cytology ...

journal_title：Infectious agents and cancer

authors： Musa J,Achenbach CJ,Evans CT,Jordan N,Daru PH,Silas O,Sagay AS,Anorlu R,Mehta SD,Wehbe F,Simon MA,Adewole IF,Hou L,Murphy RL

更新日期：2019-11-29 00:00:00

abstract：BACKGROUND:Human papillomavirus type 16 (HPV-16) infection is an important cause of cervical cancer, other anogenital cancers and, possibly, some oral and pharyngeal cancers. The association of HPV-16 with oesophageal and with prostate cancers has not been firmly established. METHODS:We analysed sera from 3,757 HIV se...

journal_title：Infectious agents and cancer

authors： Sitas F,Urban M,Stein L,Beral V,Ruff P,Hale M,Patel M,O'Connell D,Yu XQ,Verzijden A,Marais D,Williamson AL

更新日期：2007-03-02 00:00:00

abstract：BACKGROUND:Cervical cancer is the fourth most common cancer in women worldwide with highest incidence reported in Eastern Africa in 2012. The primary goal of this study was to study the expression of p16INK4a in squamous cell carcinoma (SCC) of the cervix by immunohistochemistry (IHC) and determine relation with clinic...

journal_title：Infectious agents and cancer

authors： Sarwath H,Bansal D,Husain NE,Mohamed M,Sultan AA,Bedri S

更新日期：2017-09-30 00:00:00

abstract：BACKGROUND:Recent studies have revealed the positive antiproliferative and cytotoxic effects of antiviral agents in cancer treatment. The real effect of adjuvant antiviral therapy is still controversial due to the lack of studies in biochemical mechanisms. Here, we studied the effect of the antiviral agent acyclovir on...

journal_title：Infectious agents and cancer

authors： Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D

更新日期：2017-03-23 00:00:00

abstract：:Meat is a crucial nutrient for human health since it represents a giant supply of proteins, minerals, and vitamins. On the opposite hand, the intake of red and processed meat is taken into account dangerous due to its potential of carcinogenesis and cancer risk improvement, particularly for colorectal cancer (CRC), al...

journal_title：Infectious agents and cancer

authors： Cascella M,Bimonte S,Barbieri A,Del Vecchio V,Caliendo D,Schiavone V,Fusco R,Granata V,Arra C,Cuomo A

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined. The aim of this study was to analyze the presence and functionality of human papillomavirus (HPV) and polyomaviruses (BKPyV and JCPyV) in prostate carcinomas in Chilean patie...

journal_title：Infectious agents and cancer

authors： Rodríguez H,Levican J,Muñoz JP,Carrillo D,Acevedo ML,Gaggero A,León O,Gheit T,Espinoza-Navarro O,Castillo J,Gallegos I,Tommasino M,Aguayo F

更新日期：2015-09-01 00:00:00

abstract：:Thymoquinone (TQ) is the principal active monomer isolated from the seed of the medicinal plant Nigella sativa. This compound has antitumor effects against various types of cancer including hepatocellular carcinoma (HCC), mainly due to its anti-inflammatory and anti-oxidant properties. Several pre-clinical studies sho...

journal_title：Infectious agents and cancer

authors： Bimonte S,Albino V,Barbieri A,Tamma ML,Nasto A,Palaia R,Molino C,Bianco P,Vitale A,Schiano R,Giudice A,Cascella M

更新日期：2019-04-16 00:00:00

abstract：BACKGROUND:Morbidity and mortality data highlight prostate cancer as the most commonly diagnosed neoplasm in Jamaican males. This report examines the association between dietary patterns and risk of prostate cancer in Jamaican men. MATERIALS AND METHODS:Case-control study of 204 histologically confirmed newly diagnose...

journal_title：Infectious agents and cancer

authors： Jackson M,Walker S,Simpson C,McFarlane-Anderson N,Bennett F

更新日期：2009-02-10 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract and is the third leading cause of cancer death worldwide. Epstein-Barr virus (EBV) has been associated with approximately 10% of the total cases of gastric carcinomas. No previous study has analyzed the prevalence of EBV in...

journal_title：Infectious agents and cancer

authors： Nogueira C,Mota M,Gradiz R,Cipriano MA,Caramelo F,Cruz H,Alarcão A,E Sousa FC,Oliveira F,Martinho F,Pereira JM,Figueiredo P,Leitão M

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:To clarify the immunological alterations leading to classical Kaposi sarcoma (cKS) among people infected with KS-associated herpesvirus (KSHV). METHODS:In a population-based study of 119 cKS cases, 105 KSHV-seropositive controls, and 155 KSHV-seronegative controls, we quantified plasma soluble cluster of di...

journal_title：Infectious agents and cancer

authors： Pelser C,Middeldorp J,Mbulaiteye SM,Lauria C,Messina A,Viviano E,Romano N,Vitale F,Goedert JJ

更新日期：2010-10-12 00:00:00

abstract：BACKGROUND:It has been hypothesized that human cytomegalovirus (HCMV) may be associated with breast cancer progression. However, the role of HCMV infection in breast cancer remains controversial. We aimed to assess whether HCMV genes (UL122 and UL83) could be detected in breast carcinomas and reinvestigated their possi...

journal_title：Infectious agents and cancer

authors： Utrera-Barillas D,Valdez-Salazar HA,Gómez-Rangel D,Alvarado-Cabrero I,Aguilera P,Gómez-Delgado A,Ruiz-Tachiquin ME

更新日期：2013-04-04 00:00:00

abstract：:A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies ...

journal_title：Infectious agents and cancer

authors： Lin F,Zeng A,Yang N,Lin H,Yang E,Wang S,Pintel D,Qiu J

更新日期：2007-01-31 00:00:00

abstract：BACKGROUND:Most malignant lymphomas in HIV-patients are caused by reactivation of EBV-infection. Some lymphomas have a very rapid fulminant course. HHV-8 has also been reported to be a cause of lymphoma. The role of CMV in the development of lymphoma is not clear, though both CMV and HHV-8 have been reported in tissues...

journal_title：Infectious agents and cancer

authors： Grützmeier S,Porwit A,Schmitt C,Sandström E,Åkerlund B,Ernberg I

更新日期：2016-08-22 00:00:00

abstract：Background:Tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are recommended as the first-line choices regarding the treatment of chronic hepatits B. The impact of the two antiviral agents on prognosis of Chronic hepatitis B (CHB) related hepatocellular carcinoma (HCC) remains to be explored. We aim to investigat...

journal_title：Infectious agents and cancer

authors： Zhang M,Wang D,Liu H,Li H

更新日期：2018-06-08 00:00:00

abstract：:Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HI...

journal_title：Infectious agents and cancer

authors： Zuze T,Painschab MS,Seguin R,Kudowa E,Kaimila B,Kasonkanji E,Tomoka T,Dhungel BM,Mulenga M,Chikasema M,Tewete B,Ntangwanika A,Chiyoyola S,Chimzimu F,Kampani C,Krysiak R,Montgomery ND,Fedoriw Y,Gopal S

更新日期：2018-06-28 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinomas (NPC) are consistently associated with the Epstein-Barr virus (EBV). Though NPCs are more radiosensitive and chemosensitive than other tumors of the upper aero-digestive tract, many therapeutic challenges remain. In a previous report, we have presented data supporting a possible the...

journal_title：Infectious agents and cancer

authors： Vérillaud B,Gressette M,Morel Y,Paturel C,Herman P,Lo KW,Tsao SW,Wassef M,Jimenez-Pailhes AS,Busson P

更新日期：2012-12-03 00:00:00

abstract：BACKGROUND:Lymphoma is highly associated with HIV in sub-Saharan Africa (SSA), which contributes to worse outcomes relative to resource-rich settings, and frequent failure of first-line chemotherapy. However, there are no second-line treatment descriptions for adults with relapsed or refractory lymphoma (RRL) in SSA. ...

journal_title：Infectious agents and cancer

authors： Kaimila B,van der Gronde T,Stanley C,Kasonkanji E,Chikasema M,Tewete B,Fox P,Gopal S

更新日期：2017-08-09 00:00:00

abstract：Background:The detection of the Epstein-Barr capsid antigen (VCA) immunoglobulin A (IgA) is widely used in the diagnosis of nasopharyngeal carcinoma (NPC), but a reference standard for evaluating the presence of VCA-IgA is not yet available. Therefore, a reference standard is urgently needed for a uniform and quantitat...

journal_title：Infectious agents and cancer

authors： Chen H,Zhong Q,Wu X,Ding Y,Chen Q,Xue N,Xu Y,Chen S

更新日期：2020-04-29 00:00:00

abstract：Background:The aims of this study were to evaluate whether HPV infection has a prognostic role in patients with esophageal squamous cell carcinoma who underwent oncological treatment and also to compare the heat shock proteins (Hsp) 90, 27 and 16.2 and growth hormone-releasing hormone receptor (GHRH-R) expression patte...

journal_title：Infectious agents and cancer

authors： Bognár L,Hegedűs I,Bellyei S,Pozsgai É,Zoltán L,Gombos K,Horváth ÖP,Vereczkei A,Papp A

更新日期：2018-11-29 00:00:00

abstract：Background:Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the targeting specificity of E7 methyla...

journal_title：Infectious agents and cancer

authors： Na Rangsee N,Yanatatsaneejit P,Pisitkun T,Somparn P,Jintaridth P,Topanurak S

更新日期：2020-02-03 00:00:00

abstract：:Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of these viruses have been found in human tumors, suggesting an etiological relationship with cancer. In particular,...

journal_title：Infectious agents and cancer

authors： Levican J,Acevedo M,León O,Gaggero A,Aguayo F

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:With successful antiretroviral therapy, non-communicable diseases, including malignancies, are increasingly contributing to morbidity and mortality among HIV-infected persons. The epidemiology of AIDS-defining cancers (ADCs) and non-AIDS-defining cancers (NADCs) in HIV-infected populations in Brazil has not ...

journal_title：Infectious agents and cancer

authors： Castilho JL,Luz PM,Shepherd BE,Turner M,Ribeiro SR,Bebawy SS,Netto JS,McGowan CC,Veloso VG,Engels EA,Sterling TR,Grinsztejn B

更新日期：2015-02-02 00:00:00

abstract：:Helicobacter pylori is an important yet unproven etiological agent of gastric cancer. H. pylori infection is more prevalent in developing Asian countries like India and it is usually acquired at an early age. It has been two decades since Marshall and Warren (1984) first described curved bacilli in the stomach of ulce...

journal_title：Infectious agents and cancer

authors： Akhter Y,Ahmed I,Devi SM,Ahmed N

更新日期：2007-01-04 00:00:00

abstract：OBJECTIVE:The aim of this study was to screen for the presence of Epstein Barr Virus (EBV) among Sudanese patients with Nasopharyngeal Carcinoma (NPC). METHODS:In this study, 150 tissue samples that were previously diagnosed as having NPC were screened for the presence of EBV using Polymerase Chain Reaction (PCR). PCR...

journal_title：Infectious agents and cancer

authors： Ahmed HG,Suliman RS,El Aziz MS,Alshammari FD

更新日期：2015-02-17 00:00:00

abstract：OBJECTIVES:To evaluate the prevalence of human papillomavirus (HPV) types, and risk factors for HPV positivity across cervix, vagina and anus, we conducted a study among 138 women with human immunodeficiency virus (HIV). GOAL:Compare the prevalence of different HPV types and the risk factors for HPV positivity in thre...

journal_title：Infectious agents and cancer

authors： Gonçalves MA,Randi G,Arslan A,Villa LL,Burattini MN,Franceschi S,Donadi EA,Massad E

更新日期：2008-03-14 00:00:00

abstract：BACKGROUND:Mounting evidence suggests a causal relationship between specific bacterial infections and the development of certain malignancies. However, the possible role of the keystone periodontal pathogen, Porphyromonas gingivalis, in esophageal squamous cell carcinoma (ESCC) remains unknown. Therefore, we examined t...

journal_title：Infectious agents and cancer

authors： Gao S,Li S,Ma Z,Liang S,Shan T,Zhang M,Zhu X,Zhang P,Liu G,Zhou F,Yuan X,Jia R,Potempa J,Scott DA,Lamont RJ,Wang H,Feng X

更新日期：2016-01-19 00:00:00