当前位置： SCI文献检索 > Infectious Agents and Cancer期刊下所有文献 > The co-evolved Helicobacter pylori and gastric cancer: trinity of bacterial virulence, host susceptibility and lifestyle.

The co-evolved Helicobacter pylori and gastric cancer: trinity of bacterial virulence, host susceptibility and lifestyle.

Abstract：

:Helicobacter pylori is an important yet unproven etiological agent of gastric cancer. H. pylori infection is more prevalent in developing Asian countries like India and it is usually acquired at an early age. It has been two decades since Marshall and Warren (1984) first described curved bacilli in the stomach of ulcer and gastritis patients. This discovery has won them the Nobel Prize recently, but the debate whether H. pylori is a pathogen or a commensal organism is still hot. Associations with disease-specific factors remain elusive years after the genome sequences were made available. Cytotoxin-associated antigen A (CagA) and the so-called plasticity region cluster genes are implicated in pathogenesis of the carcinoma of stomach. Another virulence factor VacA whose role is still debatable, has recently been projected in pathology of gastric cancer. Studies of the evolution through genetic variation in H. pylori populations have provided a window into the history of human population migrations and a possible co-evolution of this pathogen with its human host. Possible symbiotic relationships were seriously debated since the discovery of this pathogen. The debate has been further intensified as some studies proposed H. pylori infection to be beneficial in some humans. In this commentary, we attempt to briefly discuss about H. pylori as a human pathogen, and some of the important issues linked to its pathophysiology in different hosts. 'We dance around in a ring and suppose, the secret sits in the middle and knows'--Robert Frost.

journal_name

Infect Agent Cancer

journal_title

Infectious agents and cancer

authors

Akhter Y,Ahmed I,Devi SM,Ahmed N

doi

10.1186/1750-9378-2-2

subject

Has Abstract

pub_date

2007-01-04 00:00:00

pages

2

issn

1750-9378

pii

1750-9378-2-2

journal_volume

2

pub_type

杂志文章

相关文献

Infectious Agents and Cancer文献大全
  • Prevalence of type-specific HPV among female university students from northern Brazil.

    abstract：BACKGROUND:Human papillomavirus (HPV) infection is associated with cervical cancer, the most frequent cancer in women from northern Brazil. Assessment of the short-term impact of HPV vaccination depends on the availability of data on the prevalence of type-specific HPV in young women in the pre-immunization period, alt...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-015-0017-x

    authors： Vieira RC,Monteiro Jdo S,Manso EP,Dos Santos MR,Tsutsumi MY,Ishikawa EA,Ferrari SF,Lima KV,de Sousa MS

    更新日期：2015-07-22 00:00:00

  • Role of chronic E. coli infection in the process of bladder cancer- an experimental study.

    abstract：UNLABELLED: BACKGROUND:Bladder cancer is a common malignancy in Egypt. A history of urinary tract infection can be considered as a risk factor for bladder cancer. Escherichia coli (E. coli) infection is responsible for 70% of urinary tract infection. This study aimed to evaluate the role of chronic E. coli infection d...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-7-19

    authors： El-Mosalamy H,Salman TM,Ashmawey AM,Osama N

    更新日期：2012-08-08 00:00:00

  • Introduction of p16INK4a as a surrogate biomarker for HPV in women with invasive cervical cancer in Sudan.

    abstract：BACKGROUND:Cervical cancer is the fourth most common cancer in women worldwide with highest incidence reported in Eastern Africa in 2012. The primary goal of this study was to study the expression of p16INK4a in squamous cell carcinoma (SCC) of the cervix by immunohistochemistry (IHC) and determine relation with clinic...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-017-0159-0

    authors： Sarwath H,Bansal D,Husain NE,Mohamed M,Sultan AA,Bedri S

    更新日期：2017-09-30 00:00:00

  • Association between oncogenic human papillomavirus type 16 and Killian polyp.

    abstract：BACKGROUND:Killian polyp (KP) is a benign lesion that arises from the maxillary sinus. The etiology of KP is unknown. The aim of this study was to investigate the potential involvement of human papilloma- (HPV) and polyoma-viruses (HPyV) infections in the onset of KP. METHODS:DNA from antral (n = 14) and nasal (n = 14...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-020-00342-3

    authors： Oton-Gonzalez L,Rotondo JC,Cerritelli L,Malagutti N,Lanzillotti C,Bononi I,Ciorba A,Bianchini C,Mazziotta C,De Mattei M,Pelucchi S,Tognon M,Martini F

    更新日期：2021-01-07 00:00:00

  • Dissecting the roles of thymoquinone on the prevention and the treatment of hepatocellular carcinoma: an overview on the current state of knowledge.

    abstract：:Thymoquinone (TQ) is the principal active monomer isolated from the seed of the medicinal plant Nigella sativa. This compound has antitumor effects against various types of cancer including hepatocellular carcinoma (HCC), mainly due to its anti-inflammatory and anti-oxidant properties. Several pre-clinical studies sho...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章,评审

    doi：10.1186/s13027-019-0226-9

    authors： Bimonte S,Albino V,Barbieri A,Tamma ML,Nasto A,Palaia R,Molino C,Bianco P,Vitale A,Schiano R,Giudice A,Cascella M

    更新日期：2019-04-16 00:00:00

  • African Organization for Research and Training in Cancer: position and vision for cancer research on the African Continent.

    abstract：:The African Organization for Research and training in Cancer (AORTIC) bases the following position statements on a critical appraisal of the state on cancer research and cancer care in Africa including information on the availability of data on cancer burden, screening and prevention for cancer in Africa, cancer care ...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-016-0110-9

    authors： Ogunbiyi JO,Stefan DC,Rebbeck TR

    更新日期：2016-12-06 00:00:00

  • HIV and cancer in Africa: mutual collaboration between HIV and cancer programs may provide timely research and public health data.

    abstract：: The eruption of Kaposi sarcoma (KS) and aggressive non-Hodgkin lymphoma (NHL) in young homosexual men in 1981 in the West heralded the onset of the human immunodeficiency virus (HIV) infection epidemic, which remains one of the biggest challenges to global public health and science ever. Because KS and NHL were incre...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-6-16

    authors： Mbulaiteye SM,Bhatia K,Adebamowo C,Sasco AJ

    更新日期：2011-10-17 00:00:00

  • Relapses of primary cutaneous anaplastic large-cell lymphoma in a female immunocompetent patient with persistent chlamydophila pneumoniae and human herpesvirus 8 infection.

    abstract：BACKGROUND:We have previously reported the case of an immunocompetent female patient with a primary cutaneous CD30+ anaplastic large-cell lymphoma (PCALCL) located on her upper right eyelid characterized by the presence of a concurrent active infection by C. pneumoniae and Human herpesvirus 8 (HHV8). This finding sugge...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-016-0079-4

    authors： Caselli E,Borghi A,Maritati M,Gafà R,Lanza G,Di Luca D,Virgili A,Contini C

    更新日期：2016-07-05 00:00:00

  • Are food patterns associated with prostate cancer in Jamaican men: a preliminary report.

    abstract：BACKGROUND:Morbidity and mortality data highlight prostate cancer as the most commonly diagnosed neoplasm in Jamaican males. This report examines the association between dietary patterns and risk of prostate cancer in Jamaican men. MATERIALS AND METHODS:Case-control study of 204 histologically confirmed newly diagnose...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-4-S1-S5

    authors： Jackson M,Walker S,Simpson C,McFarlane-Anderson N,Bennett F

    更新日期：2009-02-10 00:00:00

  • The effects of antiviral treatment on breast cancer cell line.

    abstract：BACKGROUND:Recent studies have revealed the positive antiproliferative and cytotoxic effects of antiviral agents in cancer treatment. The real effect of adjuvant antiviral therapy is still controversial due to the lack of studies in biochemical mechanisms. Here, we studied the effect of the antiviral agent acyclovir on...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-017-0128-7

    authors： Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D

    更新日期：2017-03-23 00:00:00

  • The effects of the use of platelet-rich plasma gel on local recurrence in an animal model of human fibrosarcoma.

    abstract：Background:Platelet-rich-plasma (PRP) is largely used, thanks to its properties, as wound therapy after surgical resection. Several studies and clinical findings have demonstrated that the PRP can accelerate the regeneration and the repair of tissues through the action of the platelet-derived growth factors. Material ...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-019-0237-6

    authors： Barbieri A,Bimonte S,Loquercio G,Rea D,Cascella M,Anniciello A,Luciano A,Palma G,Di Costanzo G,Rosa A,Giuliano P,Arra C

    更新日期：2019-08-28 00:00:00

  • Is human cytomegalovirus associated with breast cancer progression?

    abstract：BACKGROUND:It has been hypothesized that human cytomegalovirus (HCMV) may be associated with breast cancer progression. However, the role of HCMV infection in breast cancer remains controversial. We aimed to assess whether HCMV genes (UL122 and UL83) could be detected in breast carcinomas and reinvestigated their possi...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-8-12

    authors： Utrera-Barillas D,Valdez-Salazar HA,Gómez-Rangel D,Alvarado-Cabrero I,Aguilera P,Gómez-Delgado A,Ruiz-Tachiquin ME

    更新日期：2013-04-04 00:00:00

  • Tumor aggression among hepatitis-C related hepatocellular carcinoma patients: an observational study regarding the impact of anti-HCV therapy.

    abstract：Background:Hepatitis C virus (HCV) represents a major risk factor for hepatocellular carcinoma (HCC) development and anti-HCV therapy is a significant measure to reduce the incidence of HCC, however development of HCC in HCV treated patients is an emerging clinical problem which needs to be investigated. In this study ...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-020-00300-z

    authors： Khalid J,Umar M,Ur-Rehman T,Ali M,Khan GM

    更新日期：2020-05-27 00:00:00

  • Infrequent detection of human papillomavirus infection in head and neck cancers in the Central African Republic: a retrospective study.

    abstract：:We carried out a retrospective study on the prevalence of HPV and genotype distribution by nested PCR and nucleotide sequencing analysis, in formalin-fixed, paraffin-embedded biopsies of 135 head and neck cancers (HNC) and 29 cervical cancers received between 2009 and 2017 for diagnosis at the Laboratoire National de ...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-019-0225-x

    authors： Kofi B,Mossoro-Kpinde CD,Mboumba Bouassa RS,Péré H,Robin L,Gresenguet G,Bélec L

    更新日期：2019-04-08 00:00:00

  • Infections and cancer: debate about using vaccines as a cancer control tool.

    abstract：:In 2012, Infectious Agents and Cancer commissioned a thematic series collection of articles on Prevention of HPV related cancer. The articles have attracted wide interest and stimulated debate, including about the utility of vaccines in cancer control. The application of vaccines to cancer control fulfills a promise e...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-8-16

    authors： Mbulaiteye SM,Buonaguro FM

    更新日期：2013-05-04 00:00:00

  • HIV and cancer: a comparative retrospective study of Brazilian and U.S. clinical cohorts.

    abstract：BACKGROUND:With successful antiretroviral therapy, non-communicable diseases, including malignancies, are increasingly contributing to morbidity and mortality among HIV-infected persons. The epidemiology of AIDS-defining cancers (ADCs) and non-AIDS-defining cancers (NADCs) in HIV-infected populations in Brazil has not ...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-10-4

    authors： Castilho JL,Luz PM,Shepherd BE,Turner M,Ribeiro SR,Bebawy SS,Netto JS,McGowan CC,Veloso VG,Engels EA,Sterling TR,Grinsztejn B

    更新日期：2015-02-02 00:00:00

  • Genotypic distribution of human papillomavirus (HPV) and cervical cytology findings in 5906 Thai women undergoing cervical cancer screening programs.

    abstract：BACKGROUND:Cervical cancer is the major cause of morbidity and mortality in Thai women. Nevertheless, the preventive strategy such as HPV vaccination program has not been implemented at the national level. This study explored the HPV prevalence and genotypic distribution in a large cohort of Thai women. METHODS:A hosp...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-015-0001-5

    authors： Kantathavorn N,Mahidol C,Sritana N,Sricharunrat T,Phoolcharoen N,Auewarakul C,Teerayathanakul N,Taepisitpong C,Saeloo S,Sornsamdang G,Udomchaiprasertkul W,Krongthong W,Arnamwong A

    更新日期：2015-03-02 00:00:00

  • Seroprevalence of Human herpesvirus 8 (HHV-8) and incidence of Kaposi's sarcoma in Iran.

    abstract：: Seroepidemiological surveys show that the prevalence of human herpesvirus 8 (HHV-8) infection mostly varies in various geographical areas and reflects the local incidence of classic and endemic KS, being widespread in sub-Saharan Africa and Mediterranean countries and uncommon in the USA and Northern Europe. In the M...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-6-5

    authors： Jalilvand S,Shoja Z,Mokhtari-Azad T,Nategh R,Gharehbaghian A

    更新日期：2011-04-28 00:00:00

  • Dissecting the mechanisms and molecules underlying the potential carcinogenicity of red and processed meat in colorectal cancer (CRC): an overview on the current state of knowledge.

    abstract：:Meat is a crucial nutrient for human health since it represents a giant supply of proteins, minerals, and vitamins. On the opposite hand, the intake of red and processed meat is taken into account dangerous due to its potential of carcinogenesis and cancer risk improvement, particularly for colorectal cancer (CRC), al...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章,评审

    doi：10.1186/s13027-018-0174-9

    authors： Cascella M,Bimonte S,Barbieri A,Del Vecchio V,Caliendo D,Schiavone V,Fusco R,Granata V,Arra C,Cuomo A

    更新日期：2018-01-15 00:00:00

  • PARP inhibitors: current status and implications for anticancer therapeutics.

    abstract：:Poly(ADP-ribose) polymerases (PARPs) comprise of a large family of 17 proteins encoded by various genes which participate in genome maintenance, apoptosis, inflammatory responses and the regulation of gene expression programs. PARP inhibitors, as therapeutic agents, come into play acting on both PARP 1 and PARP 2. The...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-8-46

    authors： Usmani H,Hussain SA,Sheikh A

    更新日期：2013-12-02 00:00:00

  • HPV vaccines and cancer prevention, science versus activism.

    abstract：: The rationale behind current worldwide human papilloma virus (HPV) vaccination programs starts from two basic premises, 1) that HPV vaccines will prevent cervical cancers and save lives and, 2) have no risk of serious side effects. Therefore, efforts should be made to get as many pre-adolescent girls vaccinated in or...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-8-6

    authors： Tomljenovic L,Wilyman J,Vanamee E,Bark T,Shaw CA

    更新日期：2013-02-01 00:00:00

  • Human papillomavirus genotypes distribution among Gabonese women with normal cytology and cervical abnormalities.

    abstract：BACKGROUND:Cervical cancer is one of the most common tumors affecting women with a disproportionate mortality occurring in developing countries. Despite the high prevalence of cervical cancer and cervical neoplasia in Gabon, few studies have been performed to evaluate the prevalence and determinants of HPV infection in...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-016-0046-0

    authors： Zoa Assoumou S,Ndjoyi Mbiguino A,Mabika Mabika B,Nguizi Ogoula S,El Mzibri M,Khattabi A,Ennaji MM

    更新日期：2016-01-15 00:00:00

  • Plasmablastic lymphoma in Malawi.

    abstract：:Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HI...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-018-0195-4

    authors： Zuze T,Painschab MS,Seguin R,Kudowa E,Kaimila B,Kasonkanji E,Tomoka T,Dhungel BM,Mulenga M,Chikasema M,Tewete B,Ntangwanika A,Chiyoyola S,Chimzimu F,Kampani C,Krysiak R,Montgomery ND,Fedoriw Y,Gopal S

    更新日期：2018-06-28 00:00:00

  • The relationship between anti-HPV-16 IgG seropositivity and cancer of the cervix, anogenital organs, oral cavity and pharynx, oesophagus and prostate in a black South African population.

    abstract：BACKGROUND:Human papillomavirus type 16 (HPV-16) infection is an important cause of cervical cancer, other anogenital cancers and, possibly, some oral and pharyngeal cancers. The association of HPV-16 with oesophageal and with prostate cancers has not been firmly established. METHODS:We analysed sera from 3,757 HIV se...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-2-6

    authors： Sitas F,Urban M,Stein L,Beral V,Ruff P,Hale M,Patel M,O'Connell D,Yu XQ,Verzijden A,Marais D,Williamson AL

    更新日期：2007-03-02 00:00:00

  • Possible stimulation of anti-tumor immunity using repeated cold stress: a hypothesis.

    abstract：BACKGROUND:The phenomenon of hormesis, whereby small amounts of seemingly harmful or stressful agents can be beneficial for the health and lifespan of laboratory animals has been reported in literature. In particular, there is accumulating evidence that daily brief cold stress can increase both numbers and activity of ...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-2-20

    authors： Shevchuk NA,Radoja S

    更新日期：2007-11-13 00:00:00

  • The value of cytokine levels in triage and risk prediction for women with persistent high-risk human papilloma virus infection of the cervix.

    abstract：Background:Cervical cancer is a common cancer among women worldwide and is closely related to high-risk human papillomavirus infection (HR-HPV). The immune microenvironment is thought to play an essential role in viral infection and cancer development; however, this relationship remains controversial. Cytokines are an ...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-019-0231-z

    authors： Li B,Zhang L,Zhao J,Tan G,Zhang W,Zhang N,Tian J,Qu P

    更新日期：2019-06-28 00:00:00

  • Tenofovir decrease hepatocellular carcinoma recurrence in chronic hepatitis B patients after liver resection.

    abstract：Background:Tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are recommended as the first-line choices regarding the treatment of chronic hepatits B. The impact of the two antiviral agents on prognosis of Chronic hepatitis B (CHB) related hepatocellular carcinoma (HCC) remains to be explored. We aim to investigat...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-018-0191-8

    authors： Zhang M,Wang D,Liu H,Li H

    更新日期：2018-06-08 00:00:00

  • Viral infections in prostate carcinomas in Chilean patients.

    abstract：BACKGROUND:A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined. The aim of this study was to analyze the presence and functionality of human papillomavirus (HPV) and polyomaviruses (BKPyV and JCPyV) in prostate carcinomas in Chilean patie...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/s13027-015-0024-y

    authors： Rodríguez H,Levican J,Muñoz JP,Carrillo D,Acevedo ML,Gaggero A,León O,Gheit T,Espinoza-Navarro O,Castillo J,Gallegos I,Tommasino M,Aguayo F

    更新日期：2015-09-01 00:00:00

  • Risk of classical Kaposi sarcoma by plasma levels of Epstein-Barr virus antibodies, sCD26, sCD23 and sCD30.

    abstract：BACKGROUND:To clarify the immunological alterations leading to classical Kaposi sarcoma (cKS) among people infected with KS-associated herpesvirus (KSHV). METHODS:In a population-based study of 119 cKS cases, 105 KSHV-seropositive controls, and 155 KSHV-seronegative controls, we quantified plasma soluble cluster of di...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-5-18

    authors： Pelser C,Middeldorp J,Mbulaiteye SM,Lauria C,Messina A,Viviano E,Romano N,Vitale F,Goedert JJ

    更新日期：2010-10-12 00:00:00

  • Prostate-specific antigen, sexual behavior, and sexually transmitted infections in US men 40-59 years old, 2001-2004: a cross-sectional study.

    abstract：BACKGROUND:Sexually transmitted infections (STIs) are hypothesized to play a role in the development of prostate cancer, perhaps due to inflammation-induced oncogenesis. We assessed in a nationally representative population of middle-aged men whether sexual behavior indicators for an increased risk of genital infection...

    journal_title：Infectious agents and cancer

    pub_type： 杂志文章

    doi：10.1186/1750-9378-2-19

    authors： Werny DM,Saraiya M,Chen X,Platz EA

    更新日期：2007-10-24 00:00:00