Dissecting the roles of thymoquinone on the prevention and the treatment of hepatocellular carcinoma: an overview on the current state of knowledge.

abstract：BACKGROUND:Killian polyp (KP) is a benign lesion that arises from the maxillary sinus. The etiology of KP is unknown. The aim of this study was to investigate the potential involvement of human papilloma- (HPV) and polyoma-viruses (HPyV) infections in the onset of KP. METHODS:DNA from antral (n = 14) and nasal (n = 14...

journal_title：Infectious agents and cancer

authors： Oton-Gonzalez L,Rotondo JC,Cerritelli L,Malagutti N,Lanzillotti C,Bononi I,Ciorba A,Bianchini C,Mazziotta C,De Mattei M,Pelucchi S,Tognon M,Martini F

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:To clarify the immunological alterations leading to classical Kaposi sarcoma (cKS) among people infected with KS-associated herpesvirus (KSHV). METHODS:In a population-based study of 119 cKS cases, 105 KSHV-seropositive controls, and 155 KSHV-seronegative controls, we quantified plasma soluble cluster of di...

journal_title：Infectious agents and cancer

authors： Pelser C,Middeldorp J,Mbulaiteye SM,Lauria C,Messina A,Viviano E,Romano N,Vitale F,Goedert JJ

更新日期：2010-10-12 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major public health burden in Europe, causing an increasing level of liver-related morbidity and mortality, characterized by several regional variations in the genotypes distribution. A comprehensive review of the literature from 2000 to 2015 was used to gather country-specific d...

journal_title：Infectious agents and cancer

authors： Petruzziello A,Marigliano S,Loquercio G,Cacciapuoti C

更新日期：2016-10-12 00:00:00

abstract：Background:Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the targeting specificity of E7 methyla...

journal_title：Infectious agents and cancer

authors： Na Rangsee N,Yanatatsaneejit P,Pisitkun T,Somparn P,Jintaridth P,Topanurak S

更新日期：2020-02-03 00:00:00

abstract：:Poly(ADP-ribose) polymerases (PARPs) comprise of a large family of 17 proteins encoded by various genes which participate in genome maintenance, apoptosis, inflammatory responses and the regulation of gene expression programs. PARP inhibitors, as therapeutic agents, come into play acting on both PARP 1 and PARP 2. The...

journal_title：Infectious agents and cancer

authors： Usmani H,Hussain SA,Sheikh A

更新日期：2013-12-02 00:00:00

abstract：:Helicobacter pylori is an important yet unproven etiological agent of gastric cancer. H. pylori infection is more prevalent in developing Asian countries like India and it is usually acquired at an early age. It has been two decades since Marshall and Warren (1984) first described curved bacilli in the stomach of ulce...

journal_title：Infectious agents and cancer

authors： Akhter Y,Ahmed I,Devi SM,Ahmed N

更新日期：2007-01-04 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract and is the third leading cause of cancer death worldwide. Epstein-Barr virus (EBV) has been associated with approximately 10% of the total cases of gastric carcinomas. No previous study has analyzed the prevalence of EBV in...

journal_title：Infectious agents and cancer

authors： Nogueira C,Mota M,Gradiz R,Cipriano MA,Caramelo F,Cruz H,Alarcão A,E Sousa FC,Oliveira F,Martinho F,Pereira JM,Figueiredo P,Leitão M

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:Burkitt lymphoma is an aggressive B-cell lymphoma presenting in three clinical forms: endemic, sporadic and immunodeficiency-associated. More than 90% of endemic Burkitt lymphoma carry latent Epstein-Barr virus, whereas only 20% of sporadic Burkitt lymphoma are associated with Epstein-Barr infection. Althoug...

journal_title：Infectious agents and cancer

authors： Ambrosio MR,Navari M,Di Lisio L,Leon EA,Onnis A,Gazaneo S,Mundo L,Ulivieri C,Gomez G,Lazzi S,Piris MA,Leoncini L,De Falco G

更新日期：2014-04-14 00:00:00

abstract：BACKGROUND:Sexually transmitted infections (STIs) are hypothesized to play a role in the development of prostate cancer, perhaps due to inflammation-induced oncogenesis. We assessed in a nationally representative population of middle-aged men whether sexual behavior indicators for an increased risk of genital infection...

journal_title：Infectious agents and cancer

authors： Werny DM,Saraiya M,Chen X,Platz EA

更新日期：2007-10-24 00:00:00

abstract：:This is a summary of the 1st Academic Model Providing Access to Healthcare (AMPATH) Oncology Institute research grant writing workshop organized in collaboration with the Kenya Medical Research Institute (KEMRI) and held in Kisumu, Kenya from January 16th to 18th, 2013. The goal of this meeting was to mentor future Ke...

journal_title：Infectious agents and cancer

authors： Moormann A,Skiles J,Koros E,Asirwa FC,Busakhala N,Loehrer P

更新日期：2013-10-07 00:00:00

abstract：UNLABELLED: BACKGROUND:Liver disease is the second cause of death among HIV patients receiving highly active antiretroviral therapy (HAART) in Europe. HIV patients have a high prevalence of chronic HBV (6-10%) and HCV (33%) co-infection, and accelerated progression of viral hepatitis. Furthermore, the long duration of...

journal_title：Infectious agents and cancer

authors： De Nardo P,Viscione M,Corpolongo A,Bellagamba R,Vennarecci G,Ettorre GM,Gentilotti E,Tommasi C,Nicastri E

更新日期：2012-06-28 00:00:00

abstract：Background:The aims of this study were to evaluate whether HPV infection has a prognostic role in patients with esophageal squamous cell carcinoma who underwent oncological treatment and also to compare the heat shock proteins (Hsp) 90, 27 and 16.2 and growth hormone-releasing hormone receptor (GHRH-R) expression patte...

journal_title：Infectious agents and cancer

authors： Bognár L,Hegedűs I,Bellyei S,Pozsgai É,Zoltán L,Gombos K,Horváth ÖP,Vereczkei A,Papp A

更新日期：2018-11-29 00:00:00

abstract：:Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HI...

journal_title：Infectious agents and cancer

authors： Zuze T,Painschab MS,Seguin R,Kudowa E,Kaimila B,Kasonkanji E,Tomoka T,Dhungel BM,Mulenga M,Chikasema M,Tewete B,Ntangwanika A,Chiyoyola S,Chimzimu F,Kampani C,Krysiak R,Montgomery ND,Fedoriw Y,Gopal S

更新日期：2018-06-28 00:00:00

abstract：Background:Hepatitis C virus (HCV) represents a major risk factor for hepatocellular carcinoma (HCC) development and anti-HCV therapy is a significant measure to reduce the incidence of HCC, however development of HCC in HCV treated patients is an emerging clinical problem which needs to be investigated. In this study ...

journal_title：Infectious agents and cancer

authors： Khalid J,Umar M,Ur-Rehman T,Ali M,Khan GM

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:The human papilloma viruses (HPVs) are DNA viruses associated with benign and malignant lesions of skin and mucous membranes. The HPVs has been implicated as the cause of virtually all cervical cancers worldwide but studies showed that these viruses can cause numerous cancers in several tissues including Ora...

journal_title：Infectious agents and cancer

authors： Visalli G,Currò M,Facciolà A,Riso R,Mondello P,Laganà P,Di Pietro A,Picerno I,Spataro P

更新日期：2016-08-26 00:00:00

abstract：Background:Tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are recommended as the first-line choices regarding the treatment of chronic hepatits B. The impact of the two antiviral agents on prognosis of Chronic hepatitis B (CHB) related hepatocellular carcinoma (HCC) remains to be explored. We aim to investigat...

journal_title：Infectious agents and cancer

authors： Zhang M,Wang D,Liu H,Li H

更新日期：2018-06-08 00:00:00

abstract：OBJECTIVES:To evaluate the prevalence of human papillomavirus (HPV) types, and risk factors for HPV positivity across cervix, vagina and anus, we conducted a study among 138 women with human immunodeficiency virus (HIV). GOAL:Compare the prevalence of different HPV types and the risk factors for HPV positivity in thre...

journal_title：Infectious agents and cancer

authors： Gonçalves MA,Randi G,Arslan A,Villa LL,Burattini MN,Franceschi S,Donadi EA,Massad E

更新日期：2008-03-14 00:00:00

abstract：: The eruption of Kaposi sarcoma (KS) and aggressive non-Hodgkin lymphoma (NHL) in young homosexual men in 1981 in the West heralded the onset of the human immunodeficiency virus (HIV) infection epidemic, which remains one of the biggest challenges to global public health and science ever. Because KS and NHL were incre...

journal_title：Infectious agents and cancer

authors： Mbulaiteye SM,Bhatia K,Adebamowo C,Sasco AJ

更新日期：2011-10-17 00:00:00

abstract：BACKGROUND:The human immunodeficiency virus type 1 (HIV-1) regulatory protein, Nef, is an attractive vaccine target because it is involved in viral pathogenesis, is expressed early in the viral life cycle and harbors many T and B cell epitopes. Several clinical trials include gene-based vaccines encoding this protein. ...

journal_title：Infectious agents and cancer

authors： Bråve A,Gudmundsdotter L,Gasteiger G,Hallermalm K,Kastenmuller W,Rollman E,Boberg A,Engström G,Reiland S,Cosma A,Drexler I,Hinkula J,Wahren B,Erfle V

更新日期：2007-07-10 00:00:00

abstract：:Meat is a crucial nutrient for human health since it represents a giant supply of proteins, minerals, and vitamins. On the opposite hand, the intake of red and processed meat is taken into account dangerous due to its potential of carcinogenesis and cancer risk improvement, particularly for colorectal cancer (CRC), al...

journal_title：Infectious agents and cancer

authors： Cascella M,Bimonte S,Barbieri A,Del Vecchio V,Caliendo D,Schiavone V,Fusco R,Granata V,Arra C,Cuomo A

更新日期：2018-01-15 00:00:00

abstract：OBJECTIVE:The aim of this study was to screen for the presence of Epstein Barr Virus (EBV) among Sudanese patients with Nasopharyngeal Carcinoma (NPC). METHODS:In this study, 150 tissue samples that were previously diagnosed as having NPC were screened for the presence of EBV using Polymerase Chain Reaction (PCR). PCR...

journal_title：Infectious agents and cancer

authors： Ahmed HG,Suliman RS,El Aziz MS,Alshammari FD

更新日期：2015-02-17 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinomas (NPC) are consistently associated with the Epstein-Barr virus (EBV). Though NPCs are more radiosensitive and chemosensitive than other tumors of the upper aero-digestive tract, many therapeutic challenges remain. In a previous report, we have presented data supporting a possible the...

journal_title：Infectious agents and cancer

authors： Vérillaud B,Gressette M,Morel Y,Paturel C,Herman P,Lo KW,Tsao SW,Wassef M,Jimenez-Pailhes AS,Busson P

更新日期：2012-12-03 00:00:00

abstract：BACKGROUND:Morbidity and mortality data highlight prostate cancer as the most commonly diagnosed neoplasm in Jamaican males. This report examines the association between dietary patterns and risk of prostate cancer in Jamaican men. MATERIALS AND METHODS:Case-control study of 204 histologically confirmed newly diagnose...

journal_title：Infectious agents and cancer

authors： Jackson M,Walker S,Simpson C,McFarlane-Anderson N,Bennett F

更新日期：2009-02-10 00:00:00

abstract：Background:High risk human papillomaviruses (HPVs) have been unequivocally recognised as the necessary cause of squamous intraepithelial lesions (SIL) and invasive carcinoma of the cervix. The distribution and the role of unclassified risk HPV genotypes in cervical neoplasia has not been fully elucidated. Methods:Liqu...

journal_title：Infectious agents and cancer

authors： Annunziata C,Stellato G,Greggi S,Sanna V,Curcio MP,Losito S,Botti G,Buonaguro L,Buonaguro FM,Tornesello ML

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:MDM2 gene polymorphisms 285G/C and 344 T/A are two single nucleotide polymorphisms (SNPs) recently identified as important variants that could influence the expression of MDM2 gene through the modulation of transcription factors binding on the SNP309T/G. The 285C variant seems to present a geographically dis...

journal_title：Infectious agents and cancer

authors： Rebbani K,Ezzikouri S,Marchio A,Kandil M,Pineau P,Benjelloun S

更新日期：2014-04-07 00:00:00

abstract：BACKGROUND:RFA is a safe and effective procedure for treating unresectable primary or secondary liver malignancies, but it is not without complications. The most common reported complications include abdominal hemorrhage, bile leakage, biloma formation, hepatic abscesses, and neoplastic seeding. The aim of this study i...

journal_title：Infectious agents and cancer

authors： Izzo F,Palaia R,Albino V,Amore A,di Giacomo R,Piccirillo M,Leongito M,Nasto A,Granata V,Petrillo A,Lastoria S

更新日期：2015-04-10 00:00:00

abstract：BACKGROUND:Mounting evidence suggests a causal relationship between specific bacterial infections and the development of certain malignancies. However, the possible role of the keystone periodontal pathogen, Porphyromonas gingivalis, in esophageal squamous cell carcinoma (ESCC) remains unknown. Therefore, we examined t...

journal_title：Infectious agents and cancer

authors： Gao S,Li S,Ma Z,Liang S,Shan T,Zhang M,Zhu X,Zhang P,Liu G,Zhou F,Yuan X,Jia R,Potempa J,Scott DA,Lamont RJ,Wang H,Feng X

更新日期：2016-01-19 00:00:00

abstract：BACKGROUND:Cervical cancer is the major cause of morbidity and mortality in Thai women. Nevertheless, the preventive strategy such as HPV vaccination program has not been implemented at the national level. This study explored the HPV prevalence and genotypic distribution in a large cohort of Thai women. METHODS:A hosp...

journal_title：Infectious agents and cancer

authors： Kantathavorn N,Mahidol C,Sritana N,Sricharunrat T,Phoolcharoen N,Auewarakul C,Teerayathanakul N,Taepisitpong C,Saeloo S,Sornsamdang G,Udomchaiprasertkul W,Krongthong W,Arnamwong A

更新日期：2015-03-02 00:00:00

abstract：BACKGROUND:Although the inclusion of the HPV vaccine has been registered in Spain since 2007, vaccination rates are lower than expected. The patients wish to be vaccinated is heavily influenced by information they have received from many source. The Knowledge of primary health care professionals affects the information...

journal_title：Infectious agents and cancer

authors： Pérez MR,Violeta VB,Del Campo AV,Ruiz C,Castaño SY,Conde LP,López JS

更新日期：2015-11-16 00:00:00

abstract：:In 2012, Infectious Agents and Cancer commissioned a thematic series collection of articles on Prevention of HPV related cancer. The articles have attracted wide interest and stimulated debate, including about the utility of vaccines in cancer control. The application of vaccines to cancer control fulfills a promise e...

journal_title：Infectious agents and cancer

authors： Mbulaiteye SM,Buonaguro FM

更新日期：2013-05-04 00:00:00