African Organization for Research and Training in Cancer: position and vision for cancer research on the African Continent.

abstract：UNLABELLED: BACKGROUND:Liver disease is the second cause of death among HIV patients receiving highly active antiretroviral therapy (HAART) in Europe. HIV patients have a high prevalence of chronic HBV (6-10%) and HCV (33%) co-infection, and accelerated progression of viral hepatitis. Furthermore, the long duration of...

journal_title：Infectious agents and cancer

authors： De Nardo P,Viscione M,Corpolongo A,Bellagamba R,Vennarecci G,Ettorre GM,Gentilotti E,Tommasi C,Nicastri E

更新日期：2012-06-28 00:00:00

abstract：:Bcr-Abl plays a central role in the development of chromosome positive leukaemia. Chronic Myeloid leukaemia occurs due to increase proliferation and resistance to apoptosis by Bcr-Abl positive cells. Imatinib (STI571) is the first drug in the family of Bcr-Abl tyrosine kinase inhibitors while Nilotinib (AMN107) and Da...

journal_title：Infectious agents and cancer

authors： Mughal A,Aslam HM,Khan AM,Saleem S,Umah R,Saleem M

更新日期：2013-06-20 00:00:00

abstract：OBJECTIVE:The aim of this study was to screen for the presence of Epstein Barr Virus (EBV) among Sudanese patients with Nasopharyngeal Carcinoma (NPC). METHODS:In this study, 150 tissue samples that were previously diagnosed as having NPC were screened for the presence of EBV using Polymerase Chain Reaction (PCR). PCR...

journal_title：Infectious agents and cancer

authors： Ahmed HG,Suliman RS,El Aziz MS,Alshammari FD

更新日期：2015-02-17 00:00:00

abstract：Background:The Instituto Angolano de Controlo do Cancer (IACC) Cancer Registry in Luanda, Angola is the most ancient and organized hospital-based cancer registry in Angola and provides data on cancer cases treated in several hospital facilities in Luanda. Methods:Newly-diagnosed cancer cases (2012-2016) of IACC were c...

journal_title：Infectious agents and cancer

authors： Miguel F,Bento MJ,de Lacerda GF,Weiderpass E,Santos LL

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:The MDM2 gene is the major negative regulator of p53, a tumor suppressor protein. Single nucleotide polymorphism in promoter region of MDM2 gene leads to increased expression resulting in higher levels of MDM2 protein. This event increases the attenuation of the p53 pathway. Polymorphisms in this gene can in...

journal_title：Infectious agents and cancer

authors： Amaral CM,Cetkovská K,Gurgel AP,Cardoso MV,Chagas BS,Paiva Júnior SS,de Lima Rde C,Silva-Neto JC,Silva LA,Muniz MT,Balbino VQ,Freitas AC

更新日期：2014-07-18 00:00:00

abstract：BACKGROUND:It has been hypothesized that human cytomegalovirus (HCMV) may be associated with breast cancer progression. However, the role of HCMV infection in breast cancer remains controversial. We aimed to assess whether HCMV genes (UL122 and UL83) could be detected in breast carcinomas and reinvestigated their possi...

journal_title：Infectious agents and cancer

authors： Utrera-Barillas D,Valdez-Salazar HA,Gómez-Rangel D,Alvarado-Cabrero I,Aguilera P,Gómez-Delgado A,Ruiz-Tachiquin ME

更新日期：2013-04-04 00:00:00

abstract：BACKGROUND:A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined. The aim of this study was to analyze the presence and functionality of human papillomavirus (HPV) and polyomaviruses (BKPyV and JCPyV) in prostate carcinomas in Chilean patie...

journal_title：Infectious agents and cancer

authors： Rodríguez H,Levican J,Muñoz JP,Carrillo D,Acevedo ML,Gaggero A,León O,Gheit T,Espinoza-Navarro O,Castillo J,Gallegos I,Tommasino M,Aguayo F

更新日期：2015-09-01 00:00:00

abstract：Background:Cervical cancer is a common cancer among women worldwide and is closely related to high-risk human papillomavirus infection (HR-HPV). The immune microenvironment is thought to play an essential role in viral infection and cancer development; however, this relationship remains controversial. Cytokines are an ...

journal_title：Infectious agents and cancer

authors： Li B,Zhang L,Zhao J,Tan G,Zhang W,Zhang N,Tian J,Qu P

更新日期：2019-06-28 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major public health burden in Europe, causing an increasing level of liver-related morbidity and mortality, characterized by several regional variations in the genotypes distribution. A comprehensive review of the literature from 2000 to 2015 was used to gather country-specific d...

journal_title：Infectious agents and cancer

authors： Petruzziello A,Marigliano S,Loquercio G,Cacciapuoti C

更新日期：2016-10-12 00:00:00

abstract：:Helicobacter pylori is an important yet unproven etiological agent of gastric cancer. H. pylori infection is more prevalent in developing Asian countries like India and it is usually acquired at an early age. It has been two decades since Marshall and Warren (1984) first described curved bacilli in the stomach of ulce...

journal_title：Infectious agents and cancer

authors： Akhter Y,Ahmed I,Devi SM,Ahmed N

更新日期：2007-01-04 00:00:00

abstract：BACKGROUND:Sexually transmitted infections (STIs) are hypothesized to play a role in the development of prostate cancer, perhaps due to inflammation-induced oncogenesis. We assessed in a nationally representative population of middle-aged men whether sexual behavior indicators for an increased risk of genital infection...

journal_title：Infectious agents and cancer

authors： Werny DM,Saraiya M,Chen X,Platz EA

更新日期：2007-10-24 00:00:00

abstract：BACKGROUND:Most malignant lymphomas in HIV-patients are caused by reactivation of EBV-infection. Some lymphomas have a very rapid fulminant course. HHV-8 has also been reported to be a cause of lymphoma. The role of CMV in the development of lymphoma is not clear, though both CMV and HHV-8 have been reported in tissues...

journal_title：Infectious agents and cancer

authors： Grützmeier S,Porwit A,Schmitt C,Sandström E,Åkerlund B,Ernberg I

更新日期：2016-08-22 00:00:00

abstract：BACKGROUND:MDM2 gene polymorphisms 285G/C and 344 T/A are two single nucleotide polymorphisms (SNPs) recently identified as important variants that could influence the expression of MDM2 gene through the modulation of transcription factors binding on the SNP309T/G. The 285C variant seems to present a geographically dis...

journal_title：Infectious agents and cancer

authors： Rebbani K,Ezzikouri S,Marchio A,Kandil M,Pineau P,Benjelloun S

更新日期：2014-04-07 00:00:00

abstract：: Seroepidemiological surveys show that the prevalence of human herpesvirus 8 (HHV-8) infection mostly varies in various geographical areas and reflects the local incidence of classic and endemic KS, being widespread in sub-Saharan Africa and Mediterranean countries and uncommon in the USA and Northern Europe. In the M...

journal_title：Infectious agents and cancer

authors： Jalilvand S,Shoja Z,Mokhtari-Azad T,Nategh R,Gharehbaghian A

更新日期：2011-04-28 00:00:00

abstract：BACKGROUND:Although the inclusion of the HPV vaccine has been registered in Spain since 2007, vaccination rates are lower than expected. The patients wish to be vaccinated is heavily influenced by information they have received from many source. The Knowledge of primary health care professionals affects the information...

journal_title：Infectious agents and cancer

authors： Pérez MR,Violeta VB,Del Campo AV,Ruiz C,Castaño SY,Conde LP,López JS

更新日期：2015-11-16 00:00:00

abstract：:In 2012, Infectious Agents and Cancer commissioned a thematic series collection of articles on Prevention of HPV related cancer. The articles have attracted wide interest and stimulated debate, including about the utility of vaccines in cancer control. The application of vaccines to cancer control fulfills a promise e...

journal_title：Infectious agents and cancer

authors： Mbulaiteye SM,Buonaguro FM

更新日期：2013-05-04 00:00:00

abstract：BACKGROUND:RFA is a safe and effective procedure for treating unresectable primary or secondary liver malignancies, but it is not without complications. The most common reported complications include abdominal hemorrhage, bile leakage, biloma formation, hepatic abscesses, and neoplastic seeding. The aim of this study i...

journal_title：Infectious agents and cancer

authors： Izzo F,Palaia R,Albino V,Amore A,di Giacomo R,Piccirillo M,Leongito M,Nasto A,Granata V,Petrillo A,Lastoria S

更新日期：2015-04-10 00:00:00

abstract：BACKGROUND:Langerhans cell (LC) sarcoma (LCS) is a high-grade neoplasm with overtly malignant cytologic features and an LC phenotype. We very recently suggested that LC behaves as a reservoir for common dermotropic Merkel cell polyomavirus (MCPyV) and determined the relationship between LC histiocytosis (LCH), which ha...

journal_title：Infectious agents and cancer

authors： Murakami I,Matsushita M,Iwasaki T,Kuwamoto S,Kato M,Horie Y,Hayashi K,Gogusev J,Jaubert F,Nakamoto S,Yamakawa M,Nakamine H,Takata K,Oka T,Yoshino T

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:Human papillomavirus type 16 (HPV-16) infection is an important cause of cervical cancer, other anogenital cancers and, possibly, some oral and pharyngeal cancers. The association of HPV-16 with oesophageal and with prostate cancers has not been firmly established. METHODS:We analysed sera from 3,757 HIV se...

journal_title：Infectious agents and cancer

authors： Sitas F,Urban M,Stein L,Beral V,Ruff P,Hale M,Patel M,O'Connell D,Yu XQ,Verzijden A,Marais D,Williamson AL

更新日期：2007-03-02 00:00:00

abstract：BACKGROUND:The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease could play a role in ovarian carcinogenesis. AIM:To review the literature on studies examining the association between ovarian cancer and bacterial or ...

journal_title：Infectious agents and cancer

authors： Ingerslev K,Hogdall E,Schnack TH,Skovrider-Ruminski W,Hogdall C,Blaakaer J

更新日期：2017-05-18 00:00:00

abstract：:This is a summary of the 1st Academic Model Providing Access to Healthcare (AMPATH) Oncology Institute research grant writing workshop organized in collaboration with the Kenya Medical Research Institute (KEMRI) and held in Kisumu, Kenya from January 16th to 18th, 2013. The goal of this meeting was to mentor future Ke...

journal_title：Infectious agents and cancer

authors： Moormann A,Skiles J,Koros E,Asirwa FC,Busakhala N,Loehrer P

更新日期：2013-10-07 00:00:00

abstract：:A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies ...

journal_title：Infectious agents and cancer

authors： Lin F,Zeng A,Yang N,Lin H,Yang E,Wang S,Pintel D,Qiu J

更新日期：2007-01-31 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract and is the third leading cause of cancer death worldwide. Epstein-Barr virus (EBV) has been associated with approximately 10% of the total cases of gastric carcinomas. No previous study has analyzed the prevalence of EBV in...

journal_title：Infectious agents and cancer

authors： Nogueira C,Mota M,Gradiz R,Cipriano MA,Caramelo F,Cruz H,Alarcão A,E Sousa FC,Oliveira F,Martinho F,Pereira JM,Figueiredo P,Leitão M

更新日期：2017-07-19 00:00:00

abstract：:The evolutionarily novel genes originated through different molecular mechanisms are expressed in tumors. Sometimes the expression of evolutionarily novel genes in tumors is highly specific. Moreover positive selection of many human tumor-related genes in primate lineage suggests their involvement in the origin of new...

journal_title：Infectious agents and cancer

authors： Kozlov AP

更新日期：2016-07-19 00:00:00

abstract：:Thymoquinone (TQ) is the principal active monomer isolated from the seed of the medicinal plant Nigella sativa. This compound has antitumor effects against various types of cancer including hepatocellular carcinoma (HCC), mainly due to its anti-inflammatory and anti-oxidant properties. Several pre-clinical studies sho...

journal_title：Infectious agents and cancer

authors： Bimonte S,Albino V,Barbieri A,Tamma ML,Nasto A,Palaia R,Molino C,Bianco P,Vitale A,Schiano R,Giudice A,Cascella M

更新日期：2019-04-16 00:00:00

abstract：BACKGROUND:The human immunodeficiency virus type 1 (HIV-1) regulatory protein, Nef, is an attractive vaccine target because it is involved in viral pathogenesis, is expressed early in the viral life cycle and harbors many T and B cell epitopes. Several clinical trials include gene-based vaccines encoding this protein. ...

journal_title：Infectious agents and cancer

authors： Bråve A,Gudmundsdotter L,Gasteiger G,Hallermalm K,Kastenmuller W,Rollman E,Boberg A,Engström G,Reiland S,Cosma A,Drexler I,Hinkula J,Wahren B,Erfle V

更新日期：2007-07-10 00:00:00

abstract：BACKGROUND:Morbidity and mortality data highlight prostate cancer as the most commonly diagnosed neoplasm in Jamaican males. This report examines the association between dietary patterns and risk of prostate cancer in Jamaican men. MATERIALS AND METHODS:Case-control study of 204 histologically confirmed newly diagnose...

journal_title：Infectious agents and cancer

authors： Jackson M,Walker S,Simpson C,McFarlane-Anderson N,Bennett F

更新日期：2009-02-10 00:00:00

abstract：BACKGROUND:Human Papillomavirus (HPV) detection results comparing paraffin embedded cervical tissue and other cervical specimens have been done with varying degrees of agreement. However, studies comparing freshly frozen specimens and paraffin embedded specimens of invasive cervical carcinomas are lacking. The aim of t...

journal_title：Infectious agents and cancer

authors： Odida M,de Sanjose S,Sandin S,Quiros B,Alemany L,Lloveras B,Quint W,Kleter B,Alejo M,van Doorn LJ,Weiderpass E

更新日期：2010-09-16 00:00:00

abstract：BACKGROUND:With successful antiretroviral therapy, non-communicable diseases, including malignancies, are increasingly contributing to morbidity and mortality among HIV-infected persons. The epidemiology of AIDS-defining cancers (ADCs) and non-AIDS-defining cancers (NADCs) in HIV-infected populations in Brazil has not ...

journal_title：Infectious agents and cancer

authors： Castilho JL,Luz PM,Shepherd BE,Turner M,Ribeiro SR,Bebawy SS,Netto JS,McGowan CC,Veloso VG,Engels EA,Sterling TR,Grinsztejn B

更新日期：2015-02-02 00:00:00

abstract：Background:The aims of this study were to evaluate whether HPV infection has a prognostic role in patients with esophageal squamous cell carcinoma who underwent oncological treatment and also to compare the heat shock proteins (Hsp) 90, 27 and 16.2 and growth hormone-releasing hormone receptor (GHRH-R) expression patte...

journal_title：Infectious agents and cancer

authors： Bognár L,Hegedűs I,Bellyei S,Pozsgai É,Zoltán L,Gombos K,Horváth ÖP,Vereczkei A,Papp A

更新日期：2018-11-29 00:00:00