Abstract:
:In mature rodents, whisker-related patterns are known to be present in three levels of the brain: the brainstem trigeminal nuclei, the ventrobasal thalamus and the somatosensory cortex. These patterns have been demonstrated using neuroanatomical tracing techniques, histological and histochemical staining methods and electrophysiological recordings. The development and topography of these patterns are dependent on an intact periphery. But what governs when patterns form at the three levels? Possibilities include a controlling signal from the periphery or local mechanisms at each site, such as the arrival of afferent inputs or the maturation of target tissue. In this review, we report on the maturation of the whisker pathway in a marsupial, the wallaby, where the slow tempo of development is a feature. At each level, afferent fibres grow into the region of termination many weeks before the whisker-related pattern emerges. The results suggest that the maturity of the target tissue as well as signals from the periphery combine to trigger pattern formation at each level of the pathway.
journal_name
Trends Neuroscijournal_title
Trends in neurosciencesauthors
Waite PM,Marotte LR,Leamey CA,Mark RFdoi
10.1016/s0166-2236(97)01217-4subject
Has Abstractpub_date
1998-06-01 00:00:00pages
265-9issue
6eissn
0166-2236issn
1878-108Xpii
S0166-2236(97)01217-4journal_volume
21pub_type
杂志文章,评审abstract::Interaural time differences (ITDs) represent an important cue in sound localization and auditory scene analysis. To assess this cue the auditory system internally delays binaural inputs to compensate for the outer delay, before neurons in the brainstem detect the coincident arrival of the inputs from the two ears. Dif...
journal_title:Trends in neurosciences
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doi:10.1016/j.tins.2004.03.003
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更新日期:2012-12-01 00:00:00
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更新日期:1997-09-01 00:00:00
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