当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > AMP activation of snake muscle fructose 1,6-bisphosphatase at alkaline pH.

AMP activation of snake muscle fructose 1,6-bisphosphatase at alkaline pH.

Abstract：

:AMP, an allosteric inhibitor at neutral pH, activates snakes muscle fructose 1,6-bisphosphatase at pH 9.2. The activation is virtually unique for the snake muscle enzyme: activation was not observed for the enzymes from either human and rabbit liver or porcine kidney. The activation is Mg(2+)-dependent but was not observed until the concentration of Mg2+ reaches 1 mM. It is known that subtilisin, trypsin, or lysosomal proteases hydrolyse the N-terminal loop of fructose-1,6-bisphosphatase in the vicinity of amino acid residue 60 generating a form of the enzyme with a pH optimum at 9.2. In the presence of AMP, the pH profile of the native snake muscle enzyme resembles that of the alkaline form and modification of the highly reactive sulfhydryl group abolishes AMP activation. The fact that AMP has a dual function at different pH levels suggests that pH might be an important factor in regulating the activity of the enzyme upon binding of AMP at the allosteric site. Indeed, the mode of AMP binding to the allosteric site may differ at neutral and alkaline pH levels. A residue that ionizes with a pKa of 8.9 might be involved in this process.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Zhao FK,Xu SQ,Xu GJ

doi

10.1006/bbrc.1998.8356

subject

Has Abstract

pub_date

1998-03-27 00:00:00

pages

928-32

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(98)98356-5

journal_volume

244

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Comparative studies of polyhemic cytochromes c isolated from Desulfovibrio vulgaris (Hildenborough) and Desulfovibrio desulfuricans (Norway).

    abstract：:Cytochrome c3 (Mr 26,000) has been characterized in Desulfovibrio vulgaris (Hildenborough) and its properties compared with polyhemic cytochromes c isolated from the same organism and from D. desulfuricans (Norway). It can be described as an octaheme cytochrome c3 constituted of two identical subunits. Absorption spec...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)90047-8

    authors： Loutfi M,Guerlesquin F,Bianco P,Haladjian J,Bruschi M

    更新日期：1989-03-15 00:00:00

  • Cloning and analysis of the gene for the human puromycin-sensitive aminopeptidase.

    abstract：:The gene encoding the human puromycin-sensitive aminopeptidase (PSA) has been cloned and characterized. The human PSA gene is composed of 23 exons and 22 introns and spans approximately 40 kb of chromosome 17 at the interval 17q12-21. An analysis of the 5' end of the human PSA transcript reveals that the translational...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.0604

    authors： Thompson MW,Tobler A,Fontana A,Hersh LB

    更新日期：1999-05-10 00:00:00

  • Expression and characterization of the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II using the baculovirus expression system.

    abstract：:Sf9 cells infected with the recombinant mouse CaMKII-alpha (Ca2+/calmodulin dependent kinase II) baculovirus expressed 12-15 mg of MCaMKII-alpha per liter of cells. Approximately 50% of the MCaMKII-alpha activity could be purified using a CaM-Sepharose affinity column. The purified MCaMKII-alpha had a M(rapp) of 50 kD...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80074-9

    authors： Brickey DA,Colbran RJ,Fong YL,Soderling TR

    更新日期：1990-12-14 00:00:00

  • Effects of different zinc finger transcription factors on genomic targets.

    abstract：:We have developed a novel vector system for the efficient assembly of polydactyl zinc fingers. Next to proteins that possess short canonical TGEKP linkers between all constituting zinc fingers we constructed proteins with longer, 12 amino acid linkers between two three-finger (3F) units and between three two-finger (2...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.11.011

    authors： Neuteboom LW,Lindhout BI,Saman IL,Hooykaas PJ,van der Zaal BJ

    更新日期：2006-01-06 00:00:00

  • Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis.

    abstract：BACKGROUND:Membrane protrusions play important roles in biological processes such as cell adhesion, wound healing, migration, and sensing of the external environment. Cell protrusions are a subtype of membrane microdomains composed of cholesterol and sphingolipids, and can be disrupted by cholesterol depletion. Promini...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.03.097

    authors： Singh RD,Schroeder AS,Scheffer L,Holicky EL,Wheatley CL,Marks DL,Pagano RE

    更新日期：2013-05-10 00:00:00

  • Enhancement of the turnover number of thermostable malate dehydrogenase by deleting hydrogen bonds around the catalytic site.

    abstract：:In malate dehydrogenase from Thermus flavus, substitution of Ile for Thr189, which is involved in hydrogen-bond network around a loop containing catalytic His186, caused an increase in the turnover number at room temperatures. In order to examine the effect of disruption of the hydrogen bonds on the catalytic activity...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.1261

    authors： Nishiyama M,Kinoshita M,Kudo H,Horinouchi S,Tanokura M

    更新日期：1996-08-23 00:00:00

  • Interaction of casein kinase II with ribosomal protein L22 of Drosophila melanogaster.

    abstract：:The ubiquitous eukaryotic protein kinase CKII (casein kinase II) has been found to interact with a number of cellular proteins, either through the catalytic subunit or the regulatory subunit. Using the yeast two-hybrid screening method, we found that the catalytic subunit of Drosophila melanogaster CKII (DmCKII) inter...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(02)02396-3

    authors： Zhao W,Bidwai AP,Glover CV

    更新日期：2002-10-18 00:00:00

  • Signal transduction by receptor activator of nuclear factor kappa B in osteoclasts.

    abstract：:Receptor activator of nuclear factor kappa B (RANK) is a tumor necrosis factor receptor (TNFR) family protein that plays an important role in the regulation of bone and immune systems. Cellular responses to RANK ligand (RANKL) and the signal transduction pathways of RANK have been well characterized in osteoclasts and...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1016/s0006-291x(03)00695-8

    authors： Lee ZH,Kim HH

    更新日期：2003-05-30 00:00:00

  • miR-135a inhibition protects A549 cells from LPS-induced apoptosis by targeting Bcl-2.

    abstract：:Acute lung injury (ALI) is a severe clinical condition with high morbidity and mortality. Apoptosis is a key pathologic feature of ALI, and Bcl-2 plays an important role during the pathogenesis of ALI via the regulation of apoptosis. However, the regulation of Bcl-2 during ALI, particularly through microRNAs, remains ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.09.025

    authors： Zhao J,Li X,Zou M,He J,Han Y,Wu D,Yang H,Wu J

    更新日期：2014-10-03 00:00:00

  • The mechanism of action of DuP 721, a new antibacterial agent: effects on macromolecular synthesis.

    abstract：:Pulse labeling studies with Bacillus subtilis showed that DuP 721 inhibited protein synthesis. The IC50 of DuP 721 for protein synthesis was 0.25 micrograms/ml but it was greater than 32 micrograms/ml for RNA and DNA synthesis. In cell-free systems, DuP 721 concentrations up to 100 microM did not inhibit peptide chain...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(88)90723-1

    authors： Eustice DC,Feldman PA,Slee AM

    更新日期：1988-02-15 00:00:00

  • Involvement of calcium-sensing receptor in inhibition of lipolysis through intracellular cAMP and calcium pathways in human adipocytes.

    abstract：:The calcium-sensing receptor (CaSR) was cloned initially from the bovine parathyroid and its primary physiological role is maintaining constant blood Ca(2+) levels. Subsequently, CaSR was found to be expressed in human adipose tissue, however, its physiological functions remain unclear. In this study, the effect of Ca...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.11.129

    authors： He Y,Zhang H,Teng J,Huang L,Li Y,Sun C

    更新日期：2011-01-07 00:00:00

  • Knockdown of astrocyte elevated gene-1 inhibits tumor growth and modifies microRNAs expression profiles in human colorectal cancer cells.

    abstract：:Astrocyte elevated gene-1 (AEG-1), upregulated in various types of malignancies including colorectal cancer (CRC), has been reported to be associated with the carcinogenesis. MicroRNAs (miRNAs) are widely involved in the initiation and progression of cancer. However, the functional significance of AEG-1 and the relati...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.01.046

    authors： Huang S,Wu B,Li D,Zhou W,Deng G,Zhang K,Li Y

    更新日期：2014-02-14 00:00:00

  • N-Oleoylethanolamine inhibits glucosylation of natural ceramides in CHP-100 neuroepithelioma cells: possible implications for apoptosis.

    abstract：:We report that N-oleoylethanolamine (NOE), widely employed as a ceramidase inhibitor, also inhibits glucosylation of naturally occurring ceramides. When CHP-100 neuroepithelioma cells were exposed for 18h to non-toxic NOE concentrations (i.e. up to 70 microM), basal incorporation of labelled hexose into glucosylcerami...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.0230

    authors： Spinedi A,Di Bartolomeo S,Piacentini M

    更新日期：1999-02-16 00:00:00

  • Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: potential unusual mechanism identifies G-rich introns.

    abstract：:It is unknown how very short introns (<65 nt; termed 'ultra-short' introns) could be spliced in a massive spliceosome (>2.7 MDa) without steric hindrance. By screening an annotated human transcriptome database (H-InvDB), we identified three model ultra-short introns: the 56-nt intron in the HNRNPH1 (hnRNP H1) gene, th...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.05.112

    authors： Sasaki-Haraguchi N,Shimada MK,Taniguchi I,Ohno M,Mayeda A

    更新日期：2012-06-29 00:00:00

  • Differences in substrate specificities of monoamine oxidase A from human liver and placenta.

    abstract：:The substrate specificities of monoamine oxidase (MAO) A isolated from human placenta and of human liver expressed in yeast have been compared in homogeneous preparations with respect to Vmax and Km values for natural and synthetic substrates and Ki values for competitive inhibitors. MAO A from these two sources is kn...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)92048-o

    authors： Tan AK,Weyler W,Salach JI,Singer TP

    更新日期：1991-12-31 00:00:00

  • Effect of hypoxia on cellular adhesion to vitronectin and fibronectin.

    abstract：:Cellular invasion of extracellular matrix (ECM) occurs during normal and pathological settings. For cells to invade, they must adhere to the underlying substratum, break down barrier molecules, and detach from the substratum prior to migrating through the ECM. We previously demonstrated that incubation under reduced o...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.5618

    authors： Lash GE,Fitzpatrick TE,Graham CH

    更新日期：2001-09-28 00:00:00

  • The planar cell polarity effector protein Wdpcp (Fritz) controls epithelial cell cortex dynamics via septins and actomyosin.

    abstract：:Planar cell polarity (PCP) signaling controls polarized behaviors in diverse tissues, including the collective cell movements of gastrulation and the planar polarized beating of motile cilia. A major question in PCP signaling concerns the mechanisms linking this signaling cascade with more general cytoskeletal element...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.11.078

    authors： Park TJ,Kim SK,Wallingford JB

    更新日期：2015-01-09 00:00:00

  • hKSR-2 inhibits MEKK3-activated MAP kinase and NF-kappaB pathways in inflammation.

    abstract：:Kinase suppressor of ras (KSR) and MEKK3 (MAP kinase kinase kinase) are integral members of the MAP kinase pathway. We have recently identified a new isoform of the KSR family named human kinase suppressor of ras-2 (hKSR-2), and demonstrated that hKSR-2 negatively regulates Cot, a MAP3K family member which is importan...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.07.009

    authors： Channavajhala PL,Rao VR,Spaulding V,Lin LL,Zhang YG

    更新日期：2005-09-09 00:00:00

  • A carboxy terminal domain of the L protein of rinderpest virus possesses RNA triphosphatase activity - The first enzyme in the viral mRNA capping pathway.

    abstract：:The large protein L of negative-sense RNA viruses is a multifunctional protein involved in transcription and replication of genomic RNA. It also possesses enzymatic activities involved in capping and methylation of viral mRNAs. The pathway for mRNA capping followed by the L protein of the viruses in the Morbillivirus ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.07.026

    authors： Singh PK,Ratnam N,Narayanarao KB,Bugatha H,Karande AA,Melkote Subbarao S

    更新日期：2015-08-21 00:00:00

  • LincRNA TINCR facilitates excessive proliferation and inflammation in post-burn skin fibroblasts by directly binding with SND1 protein and inducing SND1-mediated TGF-β1 expression.

    abstract：:In this study, we found that lincRNA-TINCR was significantly upregulated in burn-injured skin tissues in vivo and heat-stimulated dermal fibroblasts in vitro, accompanied by an increase in TGF-β1 expression. TINCR overexpression promoted cell proliferation, colony formation, release of pro-inflammatory factors and exp...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.01.013

    authors： Qin G,Song Y,Guo Y,Sun Y,Zeng W

    更新日期：2019-02-19 00:00:00

  • Drastic Ca2+ sensitization of myofilament associated with a small structural change in troponin I in inherited restrictive cardiomyopathy.

    abstract：:Six missense mutations in human cardiac troponin I (cTnI) were recently found to cause restrictive cardiomyopathy (RCM). We have bacterially expressed and purified these human cTnI mutants and examined their functional and structural consequences. Inserting the human cTnI into skinned cardiac muscle fibers showed that...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.10.116

    authors： Yumoto F,Lu QW,Morimoto S,Tanaka H,Kono N,Nagata K,Ojima T,Takahashi-Yanaga F,Miwa Y,Sasaguri T,Nishita K,Tanokura M,Ohtsuki I

    更新日期：2005-12-23 00:00:00

  • Reactive oxygen species participate in liver function recovery during compensatory growth in zebrafish (Danio rerio).

    abstract：:Compensatory growth (CG) is defined as a phase of accelerated growth when the disadvantageous environment is improved, accompanied by metabolic adjustment. Here, we report that hepatic oxidative phosphorylation (OXPHOS) activity was enhanced during compensatory growth in zebrafish. Mitochondrial metabolism enabled the...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.03.149

    authors： Jia J,Zhang Y,Yuan X,Qin J,Yang G,Yu X,Wang B,Sun C,Li W

    更新日期：2018-05-05 00:00:00

  • Effect of retinoic acid on the acylation of phospholipids in granulocytes in vitro.

    abstract：:The influence of retinoic acid on the incorporation of [1-14C]palmitic acid and [1-14C]arachidonic acid into phospholipids was examined in guinea pig peritoneal granulocytes. All-trans-retinoic acid inhibited the incorporation of both fatty acids into phosphatidic acid and phosphatidylinositol. However, it stimulated ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)91622-4

    authors： Tou J

    更新日期：1983-07-18 00:00:00

  • UBE2S enhances the ubiquitination of p53 and exerts oncogenic activities in hepatocellular carcinoma.

    abstract：:Ubiquitin-conjugating enzyme E2S (UBE2S) plays pivotal roles in the progression of human cancers. However, its clinical significance and role in hepatocellular carcinoma (HCC) remain unknown. Here, we show that UBE2S is upregulated in HCC and exhibits oncogenic activities via enhancing the ubiquitination of p53. Incre...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.06.093

    authors： Pan YH,Yang M,Liu LP,Wu DC,Li MY,Su SG

    更新日期：2018-09-05 00:00:00

  • A telomerase-derived peptide regulates reactive oxygen species and hepatitis C virus RNA replication in HCV-infected cells via heat shock protein 90.

    abstract：:GV1001, a synthetic peptide derived from human telomerase, has a range of diverse biological activities, including an antioxidant function. Here, we investigated the role of GV1001 in hepatitis C virus (HCV)-infected Huh7.5 (JFH-1) cells. We showed that GV1001 inhibited the production of ROS with decreased MAP kinase ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.01.160

    authors： Lee SA,Kim J,Sim J,Kim SG,Kook YH,Park CG,Kim HR,Kim BJ

    更新日期：2016-02-26 00:00:00

  • Oxidative stress involved in the antibacterial action of different antibiotics.

    abstract：:Staphylococcus aureus and Escherichia coli sensitive to chloramphenicol incubated with this antibiotic suffered oxidative stress with increase of anion superoxide (O2-). This reactive species of oxygen was detected by chemiluminescence with lucigenin. S. aureus, E. coli, and Enterococcus faecalis sensitive to ciproflo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.03.085

    authors： Albesa I,Becerra MC,Battán PC,Páez PL

    更新日期：2004-04-30 00:00:00

  • Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants.

    abstract：:The human pregnancy-specific glycoprotein (PSG) family consists of eleven closely related molecules mainly synthesized by placental syncytiotrophoblasts and whose function(s) are unknown. They belong to the carcinoembryonic antigen (CEA) family. As a step toward understanding PSG function, we have analysed 84 PSG cDNA...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1862

    authors： Teglund S,Zhou GQ,Hammarström S

    更新日期：1995-06-15 00:00:00

  • Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: a new highly potent and fully specific agonist for opiate delta-receptors.

    abstract：:Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr (DTLET) was rationally designed as pure delta-probe from proposed models of mu and delta opiate receptors. On peripheral organs, deltakephalin displays a 3000 times higher inhibitory potency on the electrically stimulated mouse vas deferens (IC50 = 0.15 nM) as on the guinea pig...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)90318-2

    authors： Zajac JM,Gacel G,Petit F,Dodey P,Rossignol P,Roques BP

    更新日期：1983-03-16 00:00:00

  • Isolation and characterization of a cDNA that codes for a LIM-containing protein which is developmentally regulated in heart.

    abstract：:During our human heart cDNA sequencing project, we have obtained a novel cDNA clone which is very similar in DNA and amino acid sequences to a rat/mouse cysteine-rich intestinal protein (1). Sequence analysis has shown that this human cysteine-rich heart protein (hCRHP) is a protein of 77 amino acids and possesses a L...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2693

    authors： Tsui SK,Yam NY,Lee CY,Waye MM

    更新日期：1994-11-30 00:00:00

  • Negatively charged phospholipids suppress IFN-gamma production in T cells.

    abstract：:The effect of phospholipids on IFN-gamma production in mouse T cells was investigated. Phosphatidylserine (PS), which has a negatively charged head group, completely inhibited IFN-gamma production in splenic naïve T cells and antigen-dependent IFN-gamma production in Th1 clone 42-6A cells, whereas other phospholipids,...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.10.179

    authors： Yotsumoto S,Kakiuchi T,Aramaki Y

    更新日期：2005-12-30 00:00:00