Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: a new highly potent and fully specific agonist for opiate delta-receptors.

abstract：:The ΔpH-dependent/Tat pathway is unique for using only the proton motive force for driving proteins transport across the thylakoid membrane in chloroplasts. 9-aminoacridine fluorescence quenching is widely used to monitor the ΔpH developed across the thylakoid membrane in the light. However, this method suffers from l...

journal_title：Biochemical and biophysical research communications

authors： Yang H,Pu X,Wang L,Liu L,Theg SM

更新日期：2017-04-22 00:00:00

abstract：:Npr1 gene (coding for NPR-A) and Npr2 gene (coding for NPR-B) are identified as intrinsic anti-hypertrophic genes that opposes abnormal cardiac remodeling. However, the functional role of Npr1 and Npr2 genes during cardiac hypertrophic growth is not well understood. Hence, the present investigation was aimed to study ...

journal_title：Biochemical and biophysical research communications

authors： Manivasagam S,Vellaichamy E

更新日期：2017-09-16 00:00:00

abstract：:An apparently novel human plasma and urinary protein of low molecular weight was isolated from several highly purified preparations of protein HC by gel chromatography and high voltage electrophoresis with a yield of about 8 mg/g. The protein has a molecular weight of about 20,000, neutral electrophoretic mobility at ...

journal_title：Biochemical and biophysical research communications

authors： López-Otin C,Grubb AO,Méndez E

更新日期：1983-11-30 00:00:00

abstract：:Fission yeast cell division is initiated by the cdc2/cdc13-cyclin protein kinase which in its catalytically active state comprises the mitotic inducer. During interphase the cdc2/cyclin complex is assembled in an inactive state that requires cdc25+ gene function for M-phase activation. The cdc25+ product, a 76 kd phos...

journal_title：Biochemical and biophysical research communications

authors： Ducommun B,Draetta G,Young P,Beach D

更新日期：1990-02-28 00:00:00

abstract：:In this study evidence for the presence of specific cytosolic platelet-activating factor (PAF) binding sites has been presented. The equilibrium dissociation constant (Kd) as determined by Scatchard analysis was 4.29 x 10(-9) M for the cytosolic and 3.71 x 10(-9) M for the membrane fraction. The maximal number of bind...

journal_title：Biochemical and biophysical research communications

authors： Svetlov S,Nigam S

更新日期：1993-01-15 00:00:00

abstract：:The change of transferrin receptors in regenerating rat liver cells after partial hepatectomy was demonstrated. The binding of 125I-labeled transferrin to the cells began to increase after 24 h of partial hepatectomy and reached about double that of the non-operated normal rat liver cells. A Scatchard analysis of bind...

journal_title：Biochemical and biophysical research communications

authors： Tei I,Makino Y,Kadofuku T,Kanamaru I,Konno K

更新日期：1984-06-15 00:00:00

abstract：:In order to test the biological importance of amino acids in the C-terminal quarter of aminoglycoside 3'-phosphotransferase II enzyme, seven of the highly conserved residues in this region, His-188, Asp-190, Asp-208, Gly-210, Arg-211, Asp-216 and Asp-220, were changed via site-directed mutagenesis. The phenotype of ea...

journal_title：Biochemical and biophysical research communications

authors： Kocabiyik S,Perlin MH

更新日期：1992-06-30 00:00:00

abstract：:CRAMP-18 (GEKLKKIGQKIKNFFQKL) is the antibacterial sequence derived from CRMAP, a member of cathelicidin-derived antimicrobial peptides. To develop the novel antibiotic peptides useful as therapeutic drugs requires strong antibiotic activity against bacterial and fungal cells without hemolytic effect. To this goal, th...

journal_title：Biochemical and biophysical research communications

authors： Shin SY,Kang SW,Lee DG,Eom SH,Song WK,Kim JI

更新日期：2000-09-07 00:00:00

abstract：:In Caenorhabditis elegans, the vulval induction is mediated by tyrosine kinase receptor/Ras signal transduction pathway composed of the lin-3, let-23, and let-60 products. In addition to these gene products, the lin-2, lin-7, and lin-10 products are also implicated in this pathway. Lin-2 encodes a MAGUK and lin-7 enco...

journal_title：Biochemical and biophysical research communications

authors： Ide N,Hirao K,Hata Y,Takeuchi M,Irie M,Yao I,Deguchi M,Toyoda A,Nishioka H,Mizoguchi A,Takai Y

更新日期：1998-02-13 00:00:00

abstract：:An orphan G protein-coupled receptor, termed 6H1, with approximately 30% sequence identity to P2Y receptors has been proposed to be a P2Y receptor (p2y5) based solely on a radioligand binding assay with [35S]dATP alphaS [Webb et al. (1997) Biochem. Biophys. Res. Commun. 219:105-110]. Previous work in our laboratory ha...

journal_title：Biochemical and biophysical research communications

authors： Li Q,Schachter JB,Harden TK,Nicholas RA

更新日期：1997-07-18 00:00:00

abstract：:Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear DNA binding protein that participates in processes involving nicking and resealing DNA strands. A genomically unstable subpopulation of PARP-1(-/-) cells has recently been described, which disappears after stable transfection of the cells with complete PARP-1 cDNA. H...

journal_title：Biochemical and biophysical research communications

authors： Cayuela ML,Carrillo A,Ramirez P,Parrilla P,Yélamos J

更新日期：2001-07-13 00:00:00

abstract：:Two genomic clones containing the 3'-end of CYP3A7, the whole 5'-flanking region plus the first exon of CYP3A5 were isolated from two different human genomic banks and sequenced. The 5'-flanking region of CYP3A5, from nucleotide -1 to -1434, was 60% and 59% similar with the corresponding regions of CYP3A4 and CYP3A7, ...

journal_title：Biochemical and biophysical research communications

authors： Jounaïdi Y,Guzelian PS,Maurel P,Vilarem MJ

更新日期：1994-12-30 00:00:00

abstract：:The ability to identify apoptotic cells within a complex population is crucial in the research and diagnosis of normal physiology and disease states. The Cellscan mark S (CS-S) cytometer was used in this study to detect intracellular fluorescence intensity and polarization (FI and FP) in several well-established model...

journal_title：Biochemical and biophysical research communications

authors： Zurgil N,Schiffer Z,Shafran Y,Kaufman M,Deutsch M

更新日期：2000-02-05 00:00:00

abstract：:Peptides containing phosphonate based non-hydrolyzable phosphotyrosyl (pTyr) mimetics previously have been shown to be competitive inhibitors of protein-tyrosine phosphatases (PTPs). These agents suffer from low cellular penetration which is partially attributable to ionization of the phosphonate group at physiologica...

journal_title：Biochemical and biophysical research communications

authors： Kole HK,Akamatsu M,Ye B,Yan X,Barford D,Roller PP,Burke TR Jr

更新日期：1995-04-26 00:00:00

abstract：:The important role of pyruvate kinase during malarial infection has prompted the cloning of a cDNA encoding Plasmodium falciparum pyruvate kinase (pfPyrK), using mRNA from intraerythrocytic-stage malaria parasites. The full-length cDNA encodes a protein with a computed molecular weight of 55.6 kDa and an isoelectric p...

journal_title：Biochemical and biophysical research communications

authors： Chan M,Sim TS

更新日期：2005-01-07 00:00:00

abstract：:Neurons extend neurites with an increased synthesis of phosphatidylcholine (PC) that is not only a membrane component but also a functional regulator with specific fatty acid composition. To analyze the local synthesis of the PC molecular species within neurons, we combined a compartmentalized culture system with matr...

journal_title：Biochemical and biophysical research communications

authors： Sugiyama E,Yao I,Setou M

更新日期：2018-01-01 00:00:00

abstract：:Translation initiation factor 5B (IF5B) is required for initiation of protein synthesis. The solution structure of archaeal IF5B (aIF5B) was analysed by small-angle X-ray scattering (SAXS) and dynamic light scattering (DLS) and was indicated to be in both monomeric and dimeric form. Sedimentation equilibrium (SE) anal...

journal_title：Biochemical and biophysical research communications

authors： Rasmussen LC,Oliveira CL,Byron O,Jensen JM,Pedersen JS,Sperling-Petersen HU,Mortensen KK

更新日期：2011-12-09 00:00:00

abstract：:It is recognized that genetic factors play a role in the susceptibility to COPD. COPD is characterized by airflow limitation. Chronic inflammation causes small airway disease and parenchymal destruction, leading to the airflow limitation. Polymorphisms in pro-inflammatory cytokine genes may confer a risk for the devel...

journal_title：Biochemical and biophysical research communications

authors： Hegab AE,Sakamoto T,Saitoh W,Nomura A,Ishii Y,Morishima Y,Iizuka T,Kiwamoto T,Matsuno Y,Massoud HH,Massoud HM,Hassanein KM,Sekizawa K

更新日期：2005-04-22 00:00:00

abstract：:The major bovine seminal plasma protein, PDC-109, binds to choline phospholipids of the sperm plasma membrane and induces an efflux of cholesterol and choline phospholipids (cholesterol efflux), which is crucial for sperm capacitation. PDC-109 also exhibits chaperone-like activity and protects target proteins against ...

journal_title：Biochemical and biophysical research communications

authors： Singh BP,Saha I,Nandi I,Swamy MJ

更新日期：2017-12-02 00:00:00

abstract：:Activating transcription factor 3 (ATF3) is an immediate early response gene that is induced in cells exposed to a variety of stress stimuli. In this report, upon exposure of cells to ultraviolet (UV) or proteasome inhibitor MG132, ATF3 protein was induced more efficiently in cells with intact p53 allele than in those...

journal_title：Biochemical and biophysical research communications

authors： Zhang C,Gao C,Kawauchi J,Hashimoto Y,Tsuchida N,Kitajima S

更新日期：2002-10-11 00:00:00

abstract：:The ornithine decarboxylase gene of S. cerevisiae encodes a predicted protein of approximately 53 kD highly homologous with the ornithine decarboxylase of other species. However, the native enzyme has been reported as an 86 kD protein. Our molecular sieve analysis indicated a Mr = 110,000 for the native enzyme. SDS-PA...

journal_title：Biochemical and biophysical research communications

authors： Fonzi WA

更新日期：1989-08-15 00:00:00

abstract：:The murine cell surface antigen ADAM 15 is a transmembrane glycoprotein that is expressed in a variety of cells including monocytic and T cell lines and consists of a metalloprotease domain, a disintegrin domain, a cysteine-rich domain, and an epidermal growth factor (EGF)-like domain in the extracellular region. The ...

journal_title：Biochemical and biophysical research communications

authors： Shimizu E,Yasui A,Matsuura K,Hijiya N,Higuchi Y,Yamamoto S

更新日期：2003-10-03 00:00:00

abstract：:The contribution of four transport pathways to Li+ influx in human, chicken and eel erythrocytes was studied. All pathways were measured simultaneously in each kind of blood sample to avoid possible temporal variations in transport parameters. We found that: 1) Li+ influx via Na(+)-K+ pump increased 2-3 fold in the or...

journal_title：Biochemical and biophysical research communications

authors： Romano L,Battaglia M,Cordì R,Rinaldi C,Leucci S,Amato A

更新日期：1995-05-05 00:00:00

abstract：:In this paper, the circadian pattern of Clock and genes mediated by the Clock was investigated in peripheral lymphocytes of rats. Circadian rhythms of Clock are found under the regimes of constant darkness (DD) and 12-h light-12-h dark (LD12:12h), with the peak phase at CT7 and ZT21, respectively. Ten differential cDN...

journal_title：Biochemical and biophysical research communications

authors： Du YZ,Fan SJ,Meng QH,Wang GQ,Tong J

更新日期：2005-11-04 00:00:00

abstract：:The mitochondrial uncoupling protein UCP-1 uncouples respiration from ATP synthesis in brown adipose tissue (BAT) and thus energy is dissipated as heat. Recently two further isoforms have been identified which may play a similar role in other tissues. We have determined the effects of the rodent-selective beta3-adreno...

journal_title：Biochemical and biophysical research communications

authors： Emilsson V,Summers RJ,Hamilton S,Liu YL,Cawthorne MA

更新日期：1998-11-18 00:00:00

abstract：:Cytoplasmic polyadenylation element binding (CPEB) proteins are RNA-binding proteins involved in translational regulation of the specific target mRNAs and control function of various organs including brain, liver and hematopoietic system. However, the role of CPEB proteins during osteoclast differentiation remains unc...

journal_title：Biochemical and biophysical research communications

authors： Arasaki Y,Li M,Akiya T,Nozawa I,Ezura Y,Hayata T

更新日期：2020-08-06 00:00:00

abstract：:Amyloid-beta (Abeta) is the core component of senile plaques, which are the pathological markers for Alzheimer's disease and cerebral amyloid angiopathy. DNA methylation/demethylation plays a crucial role in gene regulation and could also be responsible for presentation of senescence. Oxidative stress, which may be in...

journal_title：Biochemical and biophysical research communications

authors： Chen KL,Wang SS,Yang YY,Yuan RY,Chen RM,Hu CJ

更新日期：2009-01-02 00:00:00

abstract：:Sinusoidal endothelial cells proliferate following hepatocyte regeneration in the liver after partial resection. The expressions of vascular endothelial growth factor (VEGF) and its receptors, flt-1 and KDR/flk-1, were studied by Northern blotting in isolated rat liver cells and 70% resected rat liver. VEGF was expres...

journal_title：Biochemical and biophysical research communications

authors： Mochida S,Ishikawa K,Inao M,Shibuya M,Fujiwara K

更新日期：1996-09-04 00:00:00

abstract：:PU.1 is a transcription factor found in macrophages, B cells, neutrophils, and hemopoietic stem cells. In macrophages PU.1 regulates a number of genes, including c-fms, CD11b, CD18, and FcgammaR1b. Previously, in primary macrophages PU.1 binding to the sequence GAGGAA was found to be induced by treatment with bacteria...

journal_title：Biochemical and biophysical research communications

authors： Xue Y,Alford P,Shackelford RE

更新日期：1999-01-08 00:00:00

abstract：:A small fraction of tumor cells are thought to possess the potential for both multiple-lineage differentiation and self-renewal, which underlies the cancer stem cell hypothesis. However, the differentiation mechanisms of these cells have not been elucidated due to a lack of appropriate culture methods. Here, we establ...

journal_title：Biochemical and biophysical research communications

authors： Kawamata M,Katsuda T,Yamada Y,Ochiya T

更新日期：2017-01-22 00:00:00