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Fission yeast cdc25 is a cell-cycle regulated protein.

Abstract：

:Fission yeast cell division is initiated by the cdc2/cdc13-cyclin protein kinase which in its catalytically active state comprises the mitotic inducer. During interphase the cdc2/cyclin complex is assembled in an inactive state that requires cdc25+ gene function for M-phase activation. The cdc25+ product, a 76 kd phosphoprotein, is shown to oscillate in abundance during the cell cycle, reaching a peak at G2/M, and to be sensitive to nitrogen starvation. The level of cdc25 is subject to feedback regulation involving both cdc25 and cdc2.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Ducommun B,Draetta G,Young P,Beach D

doi

10.1016/0006-291x(90)91765-k

subject

Has Abstract

pub_date

1990-02-28 00:00:00

pages

301-9

issue

1

eissn

0006-291X

issn

1090-2104

pii

0006-291X(90)91765-K

journal_volume

167

pub_type

杂志文章

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