Sequences related to mouse mammary tumor virus genome in tumor cells and lymphocytes from patients with breast cancer.

abstract：:We have constructed an expression plasmid for regulated expression of the hepatitis B surface antigen gene in yeast using promoter of the yeast Pho5 gene. In the yeast transformants, the monomeric HBsAg (22K dalton) was estimated to constitute approximately 3% of the total proteins. On extraction, the HBsAg was found ...

journal_title：Biochemical and biophysical research communications

authors： Choo KB,Wu SM,Lee HH,Lo SC

更新日期：1985-08-30 00:00:00

abstract：:Recent progress in the field of mesenchymal stem cell (MSC) biology has enabled their clinical application. In the autologous cell transplantation therapy, the source of MSCs are quite important to reduce patients' physical burden. In this study, we isolated MSCs from the synovial fluid (SF) and synovial membrane (Syn...

journal_title：Biochemical and biophysical research communications

authors： Amemiya M,Tsuji K,Katagiri H,Miyatake K,Nakagawa Y,Sekiya I,Muneta T,Koga H

更新日期：2020-03-05 00:00:00

abstract：:We have obtained the optimized geometrical structure of 2-(1-carboxy-1-hydroxyethyl)-3,4-dimethylthiazolium dipolar ion and investigated its geometric and electric changes during decarboxylation process by the MNDO-PM3 method, a molecular orbital method. The salient features of the optimized structure are that the dih...

journal_title：Biochemical and biophysical research communications

authors： Nakajima Y,Sakagishi Y,Shiibashi M,Suzuki Y,Kato H

更新日期：1993-08-31 00:00:00

abstract：:Human lymphocyte growth response to mitogen was examined in vitro under different conditions to monitor aspects of carbohydrate utilization in three groups: obese nondiabetic, obese/NIDDM, and normal-weight individuals. Although lymphocyte growth capacity in minimal medium for these three groups was found to be simila...

journal_title：Biochemical and biophysical research communications

authors： Tu KY,Matthews R,Topek NH,Matthews KS

更新日期：1994-07-29 00:00:00

abstract：:Estrogen deficiency-induced obesity has a high risk of visceral fat accumulation and body weight gain. It is also associated with many adverse health conditions. Taheebo extract from Tabebuia avellanedae has been recognized as playing several biological and pharmacological roles. Therefore, we investigated whether the...

journal_title：Biochemical and biophysical research communications

authors： Iwamoto K,Fukuda Y,Tokikura C,Noda M,Yamamoto A,Yamamoto M,Yamashita M,Zaima N,Iida A,Moriyama T

更新日期：2016-09-23 00:00:00

abstract：:Substantial evidence suggests that peroxynitrite generated from the bi-radical reaction of nitric oxide and superoxide is critically involved in the pathogenesis of neurodegenerative disorders, such as Parkinson's disease. Reaction with sulfhydryl (SH)-containing molecules has been proposed to be a major detoxificatio...

journal_title：Biochemical and biophysical research communications

authors： Cao Z,Hallur S,Qiu HZ,Peng X,Li Y

更新日期：2004-04-16 00:00:00

abstract：:Two genes encoding family 11 endo-beta-1,4-xylanases (XylA, XylB) from Fusarium graminearum were cloned and expressed in Escherichia coli. The amount of active endoxylanase in the cytoplasmic soluble fraction was considerably improved by varying different expression parameters, including host strain and temperature du...

journal_title：Biochemical and biophysical research communications

authors： Beliën T,Van Campenhout S,Van Acker M,Volckaert G

更新日期：2005-02-11 00:00:00

abstract：:The potential association of CD2AP with the adherens junction protein E-cadherin, co-localization with the actin cytoskeleton, and involvement in cell migration was investigated in cultured rat gastric mucosal cells. In stationary cells, CD2AP was localized perinuclearly while E-cadherin was expressed along cell-cell ...

journal_title：Biochemical and biophysical research communications

authors： Mustonen H,Lepistö A,Lehtonen S,Lehtonen E,Puolakkainen P,Kivilaakso E

更新日期：2005-07-01 00:00:00

abstract：:Previously we reported that the activity of protein kinase FA/glycogen synthase kinase-3alpha (kinase FA/GSK-3alpha) can be detected in several brain membrane fractions. In this report, we examined whether kinase FA/GSK-3alpha can directly interact with membrane phospholipids by using anti-kinase FA/GSK-3alpha antibod...

journal_title：Biochemical and biophysical research communications

authors： Yu JS,Chan WH,Yang SD

更新日期：1997-08-18 00:00:00

abstract：:Upon N-demethylation of caffeine (CA) by rat and human liver microsomes, theobromine (TB), paraxanthine (PX), and theophylline (TP) are produced. The optimal pHs for the formation of TB, PX, and TP from CA by rat liver microsomes are 7.4 (most), 8.2 (minor) and 8.6 (moderate). At pH 7.4, PX is the primary metabolite f...

journal_title：Biochemical and biophysical research communications

authors： Chung WG,Cha YN

更新日期：1997-06-27 00:00:00

abstract：:The transcription of a mouse genomic segment containing four tRNA genes, coding for a tRNA(Ala), a tRNA(Ile), a tRNA(Pro) and a tRNA(Lys), has been studied in a HeLa cell extract, demonstrating that differences among their transcriptional efficiencies are evident using as templates either the natural cluster or an equ...

journal_title：Biochemical and biophysical research communications

authors： Russo T,Oliva A,Duilio A,Ammendola R,Costanzo F,Zannini M,Cimino F

更新日期：1987-12-31 00:00:00

abstract：:Free radicals attack lipid molecules and initiate a chain of reactions that may trigger several diseases such as atherosclerosis and cancer. Several markers of oxidative stress have been proposed, including measurements of lipid peroxides and short-chain aldehydes levels and evaluation of conjugated diene formation. A...

journal_title：Biochemical and biophysical research communications

authors： Visioli F,Colombo C,Galli C

更新日期：1998-04-17 00:00:00

abstract：:Disturbance of endoplasmic reticulum (ER) homeostasis causes ER stress (ERS), and triggers the unfolded protein response (UPR) that consequently reduces accumulation of unfolded proteins by increasing the quantity of ER chaperones. Calumenin, a Ca(2+)-binding protein with multiple EF hand motifs, which is located in t...

journal_title：Biochemical and biophysical research communications

authors： Lee JH,Kwon EJ,Kim DH

更新日期：2013-09-27 00:00:00

abstract：:Myeloperoxidase (MPO) is a glycosylated heme-containing enzyme present in the azurophilic granules of normal human polymorphonuclear neutrophils. This enzyme plays a major role in the microbicidal activity of the host defense system by catalyzing the formation of the potent oxidant, hypochlorous acid. Although the ami...

journal_title：Biochemical and biophysical research communications

authors： Taylor KL,Uhlinger DJ,Kinkade JM Jr

更新日期：1992-09-30 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders and is characterized by impaired attention, hyperactivity, and impulsivity. While multiple etiologies are implicated in ADHD, its underlying mechanism(s) remain unclear. Although previous studies have suggested dysre...

journal_title：Biochemical and biophysical research communications

authors： Nguyen Nguyen HT,Kato H,Sato H,Yamaza H,Sakai Y,Ohga S,Nonaka K,Masuda K

更新日期：2019-06-11 00:00:00

abstract：:We have used HL-60 leukemia cells to investigate phosphatidylinositol 3-kinase (PI 3-K) during granulocytic differentiation at the nuclear level. Nuclei of HL-60 cells showed a constitutive presence of PI 3-K that increased when cells were treated with differentiating doses of ATRA. PI 3-K was also detected tightly bo...

journal_title：Biochemical and biophysical research communications

authors： Marchisio M,Bertagnolo V,Colamussi ML,Capitani S,Neri LM

更新日期：1998-12-18 00:00:00

abstract：:We examined the mechanism of arachidonate release induced by somatostatin-14 (SS14) in CHO-K1 cells overexpressing rat hippocampal somatostatin receptor SSTR4. SSTR4 couples to pertussis toxin (PTX)-sensitive G-protein in CHO cells and does not lead to phosphoinositides breakdown or intracellular calcium ([Ca2+]i) mob...

journal_title：Biochemical and biophysical research communications

authors： Sakanaka C,Ferby I,Waga I,Bito H,Shimizu T

更新日期：1994-11-30 00:00:00

abstract：:Estrogen receptor (ER) is regarded as a major causal factor in breast cancer and FoxA1, a winged-helix transcription factor belonging to the forkhead family, has been found to function as a pioneer factor in the recruitment of ER to several cis-regulatory elements in the genome. High throughput chromatin immunoprecipi...

journal_title：Biochemical and biophysical research communications

authors： Liu Z,Chen S

更新日期：2010-09-10 00:00:00

abstract：:A hydrogenase from a new species of sulfate reducing bacterium has been isolated and characterized. In contrast to other hydrogenases isolated from Desulfovibrio, this enzyme is found in the cytoplasmic fraction rather than in the periplasm. The specific activity of the enzyme, as measured in the hydrogen evolution as...

journal_title：Biochemical and biophysical research communications

authors： Czechowski MH,He SH,Nacro M,DerVartanian DV,Peck HD Jr,LeGall J

更新日期：1984-12-28 00:00:00

abstract：:A major protein AA amyloid protein was purified and characterised from a Papua New Guinnean individual. This AA protein differed from all previously characterised SAA variants by the combination of Ala52, Val57, Asn60, Phe68, Phe69 and Gly72. Since the prevalence of AA-amyloidosis is unusually high in Papua New Guinea...

journal_title：Biochemical and biophysical research communications

authors： Westermark P,Sletten K,Westermark GT,Raynes J,McAdam KP

更新日期：1996-06-14 00:00:00

abstract：:A novel neuropeptide which stimulates adenylate cyclase in rat anterior pituitary cell cultures was isolated from ovine hypothalamic tissues. Its amino acid sequence was revealed as: His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln- Met-Ala- Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Ar...

journal_title：Biochemical and biophysical research communications

authors： Miyata A,Arimura A,Dahl RR,Minamino N,Uehara A,Jiang L,Culler MD,Coy DH

更新日期：1989-10-16 00:00:00

abstract：:Elevated Na(+) concentration ([Na(+)]) in the cerebrospinal fluid (CSF) contributes to the development of salt-sensitive hypertension. CSF is formed by the choroid plexus (CP) in cerebral ventricles, and [Na(+)] in CSF is controlled by transporters in CP. Here, we examined the effect of high salt diet on the expressio...

journal_title：Biochemical and biophysical research communications

authors： Guo L,Meng J,Xuan C,Ge J,Sun W,O'Rourke ST,Sun C

更新日期：2015-05-29 00:00:00

abstract：:The human homolog of the Drosophila discs large tumor suppressor protein (hDLG) functions as a scaffolding protein that facilitates the transmission of diverse downstream signals. Here we show that hDLG interacts through its PDZ domains with the carboxy-terminal S/TXV motif of the mitochondrial ribosomal protein S-34 ...

journal_title：Biochemical and biophysical research communications

authors： Ogawa F,Adachi S,Kohu K,Shige K,Akiyama T

更新日期：2003-01-17 00:00:00

abstract：:ARD1 protein is a mammalian gene product homologous to a yeast Ard1p (Arrest defective 1 protein) acetyltransferase. Although two alternative splicing products of ARD1, ARD1(235) and ARD1(225), were reported in mouse, only ARD1(235) orthologue was reported in humans. Here we show that ARD1(225) is not expressed in hum...

journal_title：Biochemical and biophysical research communications

authors： Chun KH,Cho SJ,Choi JS,Kim SH,Kim KW,Lee SK

更新日期：2007-02-02 00:00:00

abstract：:The large protein L of negative-sense RNA viruses is a multifunctional protein involved in transcription and replication of genomic RNA. It also possesses enzymatic activities involved in capping and methylation of viral mRNAs. The pathway for mRNA capping followed by the L protein of the viruses in the Morbillivirus ...

journal_title：Biochemical and biophysical research communications

authors： Singh PK,Ratnam N,Narayanarao KB,Bugatha H,Karande AA,Melkote Subbarao S

更新日期：2015-08-21 00:00:00

abstract：:Here we integrate multiple Gaussian-functions analysis into fluorescence resonance energy transfer (FRET) two-hybrid assays (Gaussian FRET two-hybrid assay) to determine the stoichiometric ratios of intracellular hetero-oligomers in single living cells. This method adopts in multiple Gaussian-functions to fit the E-co...

journal_title：Biochemical and biophysical research communications

authors： Qu W,Du M,Yang F,Mai Z,Zhang C,Lin F,Ma Y,Chen T

更新日期：2019-05-07 00:00:00

abstract：:Regulation of phospholipase D (PLD) activation by protein kinase C (PKC) was studied in membranes isolated from human promyelocytic leukemia HL60 cells. The activation of membrane-bound PLD by PKC partially purified from rat brain was most effectively induced with phorbol 12-myristate 13-acetate (PMA) and Ca2+ (1 micr...

journal_title：Biochemical and biophysical research communications

authors： Ohguchi K,Banno Y,Nakashima S,Nozawa Y

更新日期：1995-06-06 00:00:00

abstract：:Focal adhesion kinase (FAK) and integrin-linked kinase (ILK) are both involved in integrin-mediated cell migration. However, the molecular mechanism, and the relationship between FAK and ILK activity in signaling transduction for the osteopontin (OPN)-induced migration of vascular smooth muscle cells (VSMCs) remain un...

journal_title：Biochemical and biophysical research communications

authors： Li JJ,Han M,Wen JK,Li AY

更新日期：2007-04-27 00:00:00

abstract：:We show that an autocrine system for calcitonin gene-related peptide (CGRP) exists in F9 teratocarcinoma cells. Synthesis of CGRP by F9 cells was demonstrated by measuring the peptide concentration in cells and medium and by determining specific mRNA in cells. During six days of culture, CGRP secretion did not vary si...

journal_title：Biochemical and biophysical research communications

authors： Segond N,Gerbaud P,Cressent M,Lasmoles F,Taboulet J,Jullienne A,Raynaud F,Moukhtar MS,Evain-Brion D

更新日期：1992-08-31 00:00:00

abstract：:Calmodulin (CaM) plays a crucial role in metabolism and physiology of eukaryotes by regulating biological activities. Multiple lines of evidences indicate that the phosphorylated flavonoids possess relatively stronger affinities for proteins by forming non-covalent complexes with them, and that the cellular functions ...

journal_title：Biochemical and biophysical research communications

authors： Li L,Wei DQ,Wang JF,Chou KC

更新日期：2007-07-13 00:00:00