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A protein AA-variant derived from a novel serum AA protein, SAA1 delta, in an individual from Papua New Guinea.

Abstract：

:A major protein AA amyloid protein was purified and characterised from a Papua New Guinnean individual. This AA protein differed from all previously characterised SAA variants by the combination of Ala52, Val57, Asn60, Phe68, Phe69 and Gly72. Since the prevalence of AA-amyloidosis is unusually high in Papua New Guinea this AAdelta must originate from a novel SAAdelta which may represent a particularly amyloidogenic variant.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Westermark P,Sletten K,Westermark GT,Raynes J,McAdam KP

doi

10.1006/bbrc.1996.0892

subject

Has Abstract

pub_date

1996-06-14 00:00:00

pages

320-3

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(96)90892-X

journal_volume

223

pub_type

杂志文章

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