Neuron localization and neuroblastoma cell expression of brain-derived growth factor.

abstract：:Adenovirus DNA synthesis carried out in vitro was inhibited by the aphidicolin. However, 30% of the DNA synthesis was resistant to aphidicolin even at a concentration of 200 micrograms/ml. When the distribution patterns of the radioactivity of the products synthesized in the presence of 50 micrograms/ml of the drug wa...

journal_title：Biochemical and biophysical research communications

authors： Ariga H

更新日期：1983-05-31 00:00:00

abstract：:Thyrotropin receptor (TSHR) in extrathyroidal tissue, especially fat tissue, is supposed to have important roles in the development of extrathyroidal manifestations of Graves' disease. However, the molecular mechanism of TSHR expression is not known. Expression of TSHR mRNA and TSH-dependent cAMP production were obser...

journal_title：Biochemical and biophysical research communications

authors： Haraguchi K,Shimura H,Lin L,Saito T,Endo T,Onaya T

更新日期：1996-06-05 00:00:00

abstract：:The purpose of this study was to elucidate the involvement of H2O2 production in cisplatin-induced nephrotoxicity. The S3 cells were more sensitive than OMCT cells in cell viability and H2O2 production during cisplatin treatment. The cytotoxicity and H2O2 production induced by cisplatin were terminated by treatment wi...

journal_title：Biochemical and biophysical research communications

authors： Tsutsumishita Y,Onda T,Okada K,Takeda M,Endou H,Futaki S,Niwa M

更新日期：1998-01-14 00:00:00

abstract：:The peroxisome proliferator-activated receptor gamma, co-activator 1 alpha(PGC1α) effectively induced the biosynthesis of the mitochondria and the energy metabolism, and also regulated the muscle fiber-type shift. Overexpression of PGC1α gene in mice led to higher oxidative muscle fiber composition in muscle. However,...

journal_title：Biochemical and biophysical research communications

authors： Ying F,Zhang L,Bu G,Xiong Y,Zuo B

更新日期：2016-11-25 00:00:00

abstract：:Multiple types of connexin (Cxs) products, including Cx26, Cx30, Cx31, and Cx43, are found by immunolabeling in the mature cochlea. The transcript of Cx29, a newly discovered member of Cx gene family, was also discovered in the cochlea by cDNA macroarray hybridization. However, the functional roles of Cx29 in the coch...

journal_title：Biochemical and biophysical research communications

authors： Yang JJ,Liao PJ,Su CC,Li SY

更新日期：2005-12-16 00:00:00

abstract：:We have cloned the cDNA encoding human PICK1 (protein interacting with C kinase 1), a PDZ domain-containing protein of 415 amino acids, and also identified the Drosophila homologue by search of the databank. Northern blot analysis shows a single mRNA of about 2.0 kb ubiquitously expressed in human tissues. Although PI...

journal_title：Biochemical and biophysical research communications

authors： Takeya R,Takeshige K,Sumimoto H

更新日期：2000-01-07 00:00:00

abstract：:Exocytosis of secretory granules, including histamine, in rat basophilic leukemia (RBL-2H3) cells, which exhibit Ca(2+)-dependent secretion of granules when stimulated with antigen or Ca(2+)-ionophore (A23187), was observed under a video-enhanced light microscope. Exocytotic events of individual granules including fus...

journal_title：Biochemical and biophysical research communications

authors： Ozawa K,Masujima T,Ikeda K,Kodama Y,Nonomura Y

更新日期：1996-05-15 00:00:00

abstract：:Toddalia asiatica (L.) Lam. (T. asiatica) has been utilized traditionally for medicinal purposes such as the treatment of diabetes. Currently, the extract is considered to be a good source of anti-diabetic agents, but the active compounds have yet to be identified. In this study, we investigated the effects of fractio...

journal_title：Biochemical and biophysical research communications

authors： Watanabe A,Kato T,Ito Y,Yoshida I,Harada T,Mishima T,Fujita K,Watai M,Nakagawa K,Miyazawa T

更新日期：2014-10-31 00:00:00

abstract：:Cathepsin E is a major intracellular aspartic protease which is predominantly present in the cells of immune system and is frequently implicated in antigen processing via the MHC class II pathway. In the present review some of the known features of cathepsin E such as tissue distribution, subcellular localization, enz...

journal_title：Biochemical and biophysical research communications

authors： Zaidi N,Kalbacher H

更新日期：2008-03-14 00:00:00

abstract：:To address the role of brain gangliosides in synaptic activity, the ceramide analogs, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP) and its enantiomer, L-PDMP, were used to inhibit and stimulate ganglioside biosynthesis in cultured cortical neurons. Prolonged treatment with both PDMP isomers exhibi...

journal_title：Biochemical and biophysical research communications

authors： Inokuchi J,Mizutani A,Jimbo M,Usuki S,Yamagishi K,Mochizuki H,Muramoto K,Kobayashi K,Kuroda Y,Iwasaki K,Ohgami Y,Fujiwara M

更新日期：1997-08-28 00:00:00

abstract：:We studied the regulation of glutathione (GSH) synthesis and characterised the 5'-promoter region of the gamma-glutamylcysteine synthetase-heavy subunit (gammaGCS-HS) gene in human alveolar type II cells (A549) following exposure to menadione (MQ) and hydrogen peroxide (H2O2). Both MQ (100 microM) and H2O2 (100 microM...

journal_title：Biochemical and biophysical research communications

authors： Rahman I,Bel A,Mulier B,Lawson MF,Harrison DJ,Macnee W,Smith CA

更新日期：1996-12-24 00:00:00

abstract：:Mutations in the Treacher Collins syndrome gene, TCOF1, cause a disorder of craniofacial development. We manipulated the levels of Tcof1 and its protein treacle in a murine neuroblastoma cell line to identify downstream changes in gene expression using a microarray platform. We identified a set of genes that have simi...

journal_title：Biochemical and biophysical research communications

authors： Mogass M,York TP,Li L,Rujirabanjerd S,Shiang R

更新日期：2004-12-03 00:00:00

abstract：:Rab proteins, members of the Ras superfamily of small GTPases, play regulatory roles in intercompartmental vesicular transport. Each step of traffic seems to require the participation of at least one distinct Rab, with the Rab3 subfamily involved in stimulated exocytosis. We report our studies on the murine rab3D gene...

journal_title：Biochemical and biophysical research communications

authors： Adachi R,Nigam R,Tuvim MJ,DeMayo F,Dickey BF

更新日期：2000-07-14 00:00:00

abstract：:The secondary structures of and the interactions between the intracellular domains (the three loops and the C-terminal tail) of the mouse-derived prostaglandin E2 receptor EP3beta subtype were investigated using peptides mimicking the domains. The N-termini of the peptides were palmitoylated to anchor on unilamellar v...

journal_title：Biochemical and biophysical research communications

authors： Yano Y,Shimbo T,Sugimoto Y,Matsuzaki K

更新日期：2008-07-11 00:00:00

abstract：:2,3 Dehydro-2-deoxy-N-acetyl-neuraminic acid (DNANA) competitively inhibits the neuraminidase activity of Hemagglutinin-neuraminidase (HN) from Sendai virus. The inhibition constant depends on the presence of the Fusion (F) protein, which is 30 microM in the presence of active F protein and 50 microM when the F protei...

journal_title：Biochemical and biophysical research communications

authors： Dallocchio F,Tomasi M,Bellini T

更新日期：1995-03-08 00:00:00

abstract：:Kinetics of association--dissociation, competition and chromatography on two different resins, all revealed the presence of a new binding site which: specifically accepts 7-alpha-propyl spirolactone (3H-RU-26752), has little affinity for aldosterone, is present only in the target tissue (rat kidney), and is wanting in...

journal_title：Biochemical and biophysical research communications

authors： Lazar G,Agarwal MK

更新日期：1986-01-14 00:00:00

abstract：:Burkitt's lymphoma is an aggressive B-cell neoplasm resulting from deregulated c-myc expression. We have previously shown that proliferation of Burkitt's lymphoma cell lines such as Ramos is markedly reduced by iron treatment. It has been shown that iron induces expression of c-myc which, owing to its transcriptional ...

journal_title：Biochemical and biophysical research communications

authors： Habel ME,Jung D

更新日期：2006-03-24 00:00:00

abstract：:Recently, Stock et al. (J. Biol. Chem. 261, 15915-15922 [1986]) described a model enzyme system composed of horseradish peroxidase, hydrogen peroxide, phenol, glutathione and styrene. This system forms glutathione-styrene conjugates. Glutathione radicals and carbon-centered radicals are intermediates in this process. ...

journal_title：Biochemical and biophysical research communications

authors： Kanofsky JR

更新日期：1989-03-31 00:00:00

abstract：:Effect of six steroidal saponins isolated from Anemarrhenae rhizoma on superoxide generation in human neutrophils was investigated. The steroidal saponins examined were anemarrhenasaponin-I (An-I), anemarrhenasaponin-Ia (An-Ia), timosaponin B-I (TB-I), timosaponin B-II (TB-II), timosaponin B-III (TB-III) and timosapon...

journal_title：Biochemical and biophysical research communications

authors： Zhang J,Zhang M,Sugahara K,Sagara Y,Meng Z,Xu S,Kodama H

更新日期：1999-06-16 00:00:00

abstract：:Tau misfolding has been implicated in a variety of tauopathies, including Alzheimer's disease. The microtubule binding domain of tau consists of four repeat segments (R1-R4), and aggregation of these segments leads to the formation of neurofibrillary tangles. Previous studies indicate that misfolded tau associates wit...

journal_title：Biochemical and biophysical research communications

authors： Dicke SS,Tatge L,Engen PE,Culp M,Masterson LR

更新日期：2017-12-02 00:00:00

abstract：:Brush border membrane vesicles (BBMVs) prepared from midguts of Choristoneura fumiferana larvae were pretreated separately with the three CryIA delta-endotoxins from Bacillus thuringiensis subsp. kurstaki HD-1. Crossed affinity immunoelectrophoresis of the solubilized toxin-BBMV complexes, using antibodies raised agai...

journal_title：Biochemical and biophysical research communications

authors： Pang AS

更新日期：1994-03-30 00:00:00

abstract：:In Alzheimer's disease (AD), tau protein is abnormally hyperphosphorylated and aggregated into paired helical filaments (PHFs). It was discovered recently that tau is also O-GlcNAcylated in human brains. And O-GlcNAcylation may regulate phosphorylation of tau in a site-specific manner. In this work, we focused on the ...

journal_title：Biochemical and biophysical research communications

authors： Yu CH,Si T,Wu WH,Hu J,Du JT,Zhao YF,Li YM

更新日期：2008-10-10 00:00:00

abstract：:Murine embryonic stem cell (mESC)-derived cardiomyocytes represent a promising source of cells for use in the development of models for studying early cardiac development as well as cell-based therapies in postnatal pathologies. Here, we report a highly efficient cardiac differentiation system in which high density em...

journal_title：Biochemical and biophysical research communications

authors： Lee MY,Cagavi Bozkulak E,Schliffke S,Amos PJ,Ren Y,Ge X,Ehrlich BE,Qyang Y

更新日期：2011-12-09 00:00:00

abstract：:Our goal was to characterize the glucose transporter in synaptosomes and to compare it to the different forms of transporter already identified. Cross-reactivity with antibodies to the human erythrocyte transporter, Km of glucose uptake, reversibility of NEM inhibition of transport, and insulin sensitivity were all ex...

journal_title：Biochemical and biophysical research communications

authors： Bhattacharyya MV,Brodsky JL

更新日期：1988-09-15 00:00:00

abstract：:Invasion and metastasis are major causes of malignant tumor-associated mortality. The present study aimed to investigate the molecular events underlying inhibitory effect of N-benzylcantharidinamide, a novel synthetic analog of cantharidin, on matrix metalloproteinase-9 (MMP-9)-mediated invasion in highly metastatic h...

journal_title：Biochemical and biophysical research communications

authors： Lee JY,Chung TW,Choi HJ,Lee CH,Eun JS,Han YT,Choi JY,Kim SY,Han CW,Jeong HS,Ha KT

更新日期：2014-05-02 00:00:00

abstract：:[8]-Gingerol is an active component of Zinger and shows several pharmacological activities, such as antipyretic and anti-inflammation characteristics. To identify a potential skin-whitening agent, the inhibitory effects of [8]-gingerol on melanogenesis and its mechanism of action were investigated. In the present stud...

journal_title：Biochemical and biophysical research communications

authors： Huang HC,Chou YC,Wu CY,Chang TM

更新日期：2013-08-23 00:00:00

abstract：:Transgenic (TG) mice expressing porcine GH receptor (pGHR) directed by a 762-bp proximal leptin promoter were used to analyze the capability of the promoter to drive and regulate pGHR expression in vivo. Transgene expression occurred in inguinal, retroperitoneal, and epididymal/parametrial fat depots in both male and ...

journal_title：Biochemical and biophysical research communications

authors： Chen XL,Hartzell DL,McGraw RA,Hausman GJ,Dean RG

更新日期：1999-08-19 00:00:00

abstract：:Mesenchymal Stem Cells are known to engraft and integrate into the architecture of colorectal tumours, with little known regarding their fate following engraftment. This study aimed to investigate mediators of Mesenchymal Stem Cell (MSC) and colon cancer cell (CCC) interactions. Mesenchymal Stem Cells and colon cancer...

journal_title：Biochemical and biophysical research communications

authors： Hogan NM,Joyce MR,Murphy JM,Barry FP,O'Brien T,Kerin MJ,Dwyer RM

更新日期：2013-06-14 00:00:00

abstract：:Genes of the IL-1 family encode three different peptides, IL-1alpha, IL-1beta, and IL-1Ra, respectively. IL-1 operates through IL-1RI, and is involved in airway inflammation in asthmatic subjects, whereas IL-1Ra appears to be a specific competitive inhibitor of IL-1. All genes are on chromosome 2q12-21 where genomewid...

journal_title：Biochemical and biophysical research communications

authors： Mao XQ,Kawai M,Yamashita T,Enomoto T,Dake Y,Sasaki S,Kataoka Y,Fukuzumi T,Endo K,Sano H,Aoki T,Kurimoto F,Adra CN,Shirakawa T,Hopkin JM

更新日期：2000-09-24 00:00:00

abstract：:Using recombinant DNA technology, the NH2 and COOH terminal domains of the human Factor VIII molecule were co-expressed in baby hamster kidney 21 (BHK21) cells using the vaccinia virus system. Procoagulant activity was detectable in cell supernatants, thus suggesting that the central portion present in the FVIII prote...

journal_title：Biochemical and biophysical research communications

authors： Pavirani A,Meulien P,Harrer H,Dott K,Mischler F,Wiesel ML,Mazurier C,Cazenave JP,Lecocq JP

更新日期：1987-05-29 00:00:00