Abstract：
:In this microdialysis study we measured the extracellular neuropeptide Y (NPY) levels in the dorsal hippocampus of conscious rats. During potassium-induced depolarisations, a 93% increase in extracellular levels of NPY was observed. NPY has been demonstrated to reduce kainic acid-induced convulsions in rats, but it is unknown whether NPY neurotransmission is affected by seizures. During seizures induced by kainic acid we observed a 104% increase in levels of NPY, suggesting that convulsions are associated with a dramatically increased NPYergic neurotransmission.
journal_name
Brain Resjournal_title
Brain researchauthors
Husum H,Mikkelsen JD,Mørk Adoi
10.1016/s0006-8993(97)01374-7subject
Has Abstractpub_date
1998-01-19 00:00:00pages
351-4issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(97)01374-7journal_volume
781pub_type
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