Vasopressin metabolites: a link between vasopressin and memory?

Abstract:

:The effects of endogenous metabolites of the neuropeptide vasopressin (VP) in behavioural tests led to the hypothesis that VP metabolites have a more selective function than VP. In contrast to VP, no peripheral effects have been found thus far with VP metabolites and their function seems to be associated with memory-related behaviour. VP metabolites can improve both consolidation and retrieval of memory. Effects on autonomic and electrophysiological parameters and interactions with other neurotransmitter systems have provided some information about the processes that could underlie the effects of VP metabolites on memory-related behaviour. There is evidence that the effects of VP metabolites could be mediated by a VP metabolite receptor, which is different from the known VP receptors. The VP metabolite receptor could be a link between the neuropeptide VP and memory-related behaviour.

journal_name

Prog Brain Res

authors

Reijmers LG,van Ree JM,Spruijt BM,Burbach JP,De Wied D

doi

10.1016/s0079-6123(08)61591-5

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

523-35

eissn

0079-6123

issn

1875-7855

pii

S0079-6123(08)61591-5

journal_volume

119

pub_type

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