Abstract:
:The discovery of CB1 and CB2 receptors and of endogenous agonists for these receptors has sparked renewed interest in the therapeutic potential of cannabinoids. This has led to a need for strategies that will provide a better separation of wanted from unwanted effects, particularly for CB1 receptor agonists. Possible strategies are to target CB1 receptors present on neurones outside the central nervous system or novel types or subtypes of neuronal cannabinoid receptor. This paper reviews evidence for the presence of CB1 receptors on peripheral neurones and for the existence of neuronal non-CB1 cannabinoid receptors.
journal_name
Life Scijournal_title
Life sciencesauthors
Pertwee RGdoi
10.1016/s0024-3205(99)00282-9subject
Has Abstractpub_date
1999-01-01 00:00:00pages
597-605issue
6-7eissn
0024-3205issn
1879-0631pii
S0024-3205(99)00282-9journal_volume
65pub_type
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