Activation of spinal wide dynamic range neurons by intracutaneous microinjection of nicotine.

abstract：:The hearing ability of five Japanese macaques (Macaca fuscata) was assessed following two-stage bilateral auditory cortex lesions. The animals were tested using a shock-avoidance procedure with a conditioned-suppression procedure used for comparison in two cases. The animals initially were unable to respond to sound, ...

journal_title：Journal of neurophysiology

authors： Heffner HE,Heffner RS

更新日期：1986-02-01 00:00:00

abstract：:1. In order to investigate the effects of an imbalance in stimulation to the eyes without the confounding influence of continuous deprivation of one eye, we reared cats with unequal alternating monocular exposure (AME) and, for comparison, cats with equal AME. We recorded extracellularly from single cells in area 17 o...

journal_title：Journal of neurophysiology

authors： Tieman DG,McCall MA,Hirsch HV

更新日期：1983-03-01 00:00:00

abstract：:To investigate the dependence of velocity characteristics on spatiotemporal interactions the velocity selectivity of 15 geniculate and 72 cortical cells (areas 17 and 18) was examined with light and dark bars before and after masking all but the most sensitive part of the receptive field. The use of a 0.3 degree windo...

journal_title：Journal of neurophysiology

authors： Duysens J,Orban GA,Cremieux J

更新日期：1985-10-01 00:00:00

abstract：:Field potential recording was used to investigate properties of synaptic transmission and long-term potentiation (LTP) at Schaffer collateral-CA1 synapses in both hippocampal slices of mutant mice in which the alpha-subunit of the olfactory cyclic nucleotide-gated channel (alpha3/OCNC)1 was rendered null and also in s...

journal_title：Journal of neurophysiology

authors： Parent A,Schrader K,Munger SD,Reed RR,Linden DJ,Ronnett GV

更新日期：1998-06-01 00:00:00

abstract：:1. Whole-cell patch clamp techniques were used to record transient outward potassium currents in embryonic rat neocortical neurons maintained in culture. The effect of lidocaine and its quaternary derivative QX222 on this transient outward current (TOC) was examined. 2. Extracellular application of lidocaine produced ...

journal_title：Journal of neurophysiology

authors： Andreasen M,Hablitz JJ

更新日期：1993-06-01 00:00:00

abstract：:Previous studies have rarely tested whether the activity of high-frequency discharge (HFD) neurons of the basal ganglia (BG) is modulated by expectation, delivery, and omission of aversive events. Therefore the full value domain encoded by the BG network is still unknown. We studied the activity of HFD neurons of the ...

journal_title：Journal of neurophysiology

authors： Joshua M,Adler A,Rosin B,Vaadia E,Bergman H

更新日期：2009-02-01 00:00:00

abstract：:Odorants induce specific modulation of mitral/tufted (MT) cells' firing rate in the mammalian olfactory bulb (OB), inducing temporal patterns of neuronal discharge embedded in an oscillatory local field potential (LFP). While most studies have examined anesthetized animals, little is known about the firing rate and te...

journal_title：Journal of neurophysiology

authors： Fuentes RA,Aguilar MI,Aylwin ML,Maldonado PE

更新日期：2008-07-01 00:00:00

abstract：:To estimate contour-orientation sensitivity of the cat and the degree to which precortical processing contributes to such estimates, the amplitude of visually evoked potentials (VEP) recorded from the visual cortex of cats in response to a visual stimulus (S2) presented at various intervals after presentation of anoth...

journal_title：Journal of neurophysiology

authors： Tootle JS,Berkley MA

更新日期：1985-05-01 00:00:00

abstract：:The medial olivocochlear (MOC) efferent system, which innervates cochlear outer hair cells, suppresses cochlear responses. MOC-mediated suppression includes both slow and fast components, with time courses differing by three orders of magnitude. Pharmacological studies in anesthetized guinea pigs suggest that both slo...

journal_title：Journal of neurophysiology

authors： Yoshida N,Liberman MC,Brown MC,Sewell WF

更新日期：1999-12-01 00:00:00

abstract：:The continuous perception of motion-through-depth is critical for both navigation and interacting with objects in a dynamic three-dimensional (3D) world. Here we used 3D tracking to simultaneously assess the perception of motion in all directions, facilitating comparisons of responses to motion-through-depth to fronto...

journal_title：Journal of neurophysiology

authors： Bonnen K,Huk AC,Cormack LK

更新日期：2017-09-01 00:00:00

abstract：:1. We investigated the glycine-induced response in ventromedial hypothalamic (VMH) neurons freshly dissociated from 8- to 12-day-old rats using the nystatin and gramicidin perforated patch recording modes. The nystatin-formed pores in the plasma membrane are permeable for both monovalent cations and anions, whereas th...

journal_title：Journal of neurophysiology

authors： Abe Y,Furukawa K,Itoyama Y,Akaike N

更新日期：1994-10-01 00:00:00

abstract：:Neuropeptide Y (NPY) potently inhibits glutamate-mediated synaptic transmission in areas CA1 and CA3 of the rat hippocampus without affecting other synaptic inputs onto principal cells of the hippocampal formation, suggesting that its biological role may include the regulation of excitability within the hippocampus. H...

journal_title：Journal of neurophysiology

authors： Klapstein GJ,Colmers WF

更新日期：1997-09-01 00:00:00

abstract：:Neural implants with large numbers of electrodes have become an important tool for examining brain functions. However, these devices typically displace a large intracranial volume compared with the neurons they record. This large size limits the density of implants, provokes tissue reactions that degrade chronic perfo...

journal_title：Journal of neurophysiology

authors： Egert D,Pettibone JR,Lemke S,Patel PR,Caldwell CM,Cai D,Ganguly K,Chestek CA,Berke JD

更新日期：2020-12-01 00:00:00

abstract：:We studied adjustments in digit forces and moments during holding a vertically oriented handle under slow, externally imposed changes in the width of the grasp. Subjects (n = 8) grasped a customized motorized handle with five digits and held it statically in the air. The handle width either increased (expanded) or dec...

journal_title：Journal of neurophysiology

authors： Zatsiorsky VM,Gao F,Latash ML

更新日期：2006-04-01 00:00:00

abstract：:1. Intracellular recordings from CA1 pyramidal neurons in the rat hippocampal slice have been used to study synaptic transmission after maximal orthodromic stimulation of the Schaffer collateral-commissural fibers. Paired-pulse stimulation was used to investigate how the first (conditioning) stimulation influenced the...

journal_title：Journal of neurophysiology

authors： Nathan T,Lambert JD

更新日期：1991-11-01 00:00:00

abstract：:Sleep disturbances are prevalent in clinical anxiety, but it remains unclear whether they are cause and/or consequence of this condition. Fear conditioning constitutes a valid laboratory model for the acquisition of normal and pathological anxiety. To explore the relationship between disturbed sleep and anxiety in mor...

journal_title：Journal of neurophysiology

authors： Peters AC,Blechert J,Sämann PG,Eidner I,Czisch M,Spoormaker VI

更新日期：2014-09-15 00:00:00

abstract：:Some electrographic seizures are generated intracortically. The cellular and ionic bases of cortically generated spontaneous seizures are not fully understood. Here we investigated spontaneously occurring seizures consisting of spike-wave complexes intermingled with fast runs in ketamine-xylazine anesthetized cats, us...

journal_title：Journal of neurophysiology

authors： Timofeev I,Grenier F,Steriade M

更新日期：2004-08-01 00:00:00

abstract：:How neurons filter and integrate their complex patterns of synaptic inputs is central to their role in neural information processing. Synaptic filtering and integration are shaped by the frequency-dependent neuronal membrane impedance. Using single and dual dendritic recordings in vivo, pharmacology, and computational...

journal_title：Journal of neurophysiology

authors： Dewell RB,Gabbiani F

更新日期：2019-08-01 00:00:00

abstract：:This study considers the possibility of using coherence analysis for detection and measurement of synchrony (correlations) in large neural populations, applied to activities that are relatively easy to record in parallel. Mathematical analysis and computer simulations are used to examine the behavior of the coherence ...

journal_title：Journal of neurophysiology

authors： Christakos CN

更新日期：1997-12-01 00:00:00

abstract：:We have demonstrated that 4-aminopyridine-3-methanol (4-AP-3-MeOH), a 4-aminopyridine derivative, significantly restores axonal conduction in stretched spinal cord white-matter strips and shows no preference in restoring large and small axons. This compound is 10 times more potent when compared with 4-AP and other der...

journal_title：Journal of neurophysiology

authors： Sun W,Smith D,Fu Y,Cheng JX,Bryn S,Borgens R,Shi R

更新日期：2010-01-01 00:00:00

abstract：:There are at least two respiration-related rhythm generators in the medulla: the pre-Bötzinger complex, which produces inspiratory (Insp) neuron bursts, and the parafacial respiratory group (pFRG), which produces predominantly preinspiratory (Pre-I) neuron bursts. The pFRG Pre-I neuron activity has not been correlated...

journal_title：Journal of neurophysiology

authors： Onimaru H,Kumagawa Y,Homma I

更新日期：2006-07-01 00:00:00

abstract：:Long-term synaptic depression (LTD) of cerebellar parallel fiber-Purkinje cell synapses is a form of use-dependent synaptic plasticity that may be studied in cell culture. One form of LTD is induced postsynaptically through an mGlu1/Ca influx/protein kinase Cα (PKCα) cascade, and its initial expression requires phosph...

journal_title：Journal of neurophysiology

authors： Linden DJ

更新日期：2012-01-01 00:00:00

abstract：:The operculoinsular cortical region has a major role in the representation of noxious stimuli, based on functional imaging observations, clinical lesion studies, and EEG recordings of specifically pain-related laser-evoked potentials (LEPs) in humans. The source of LEPs has not been identified, and several somatic rep...

journal_title：Journal of neurophysiology

authors： Baumgärtner U,Tiede W,Treede RD,Craig AD

更新日期：2006-11-01 00:00:00

abstract：:Frequency facilitation is a process whereby neurosecretion increases as a function of stimulation frequency during repetitive synaptic activity. To examine the physiological basis underlying facilitation, we have estimated the frequency dependence of the synaptic parameters n (number of units capable of responding to ...

journal_title：Journal of neurophysiology

authors： Worden MK,Bykhovskaia M,Hackett JT

更新日期：1997-07-01 00:00:00

abstract：:The role of potassium channels in regulating spontaneous firing and sound-evoked responses in the central nucleus of the inferior colliculus was studied by recording single-unit activity before and during iontophoretic application of a nonspecific potassium channel blocker, tetraethylammonium (TEA). Tone bursts and si...

journal_title：Journal of neurophysiology

authors： Zhang H,Wu SH,Kelly JB

更新日期：2004-05-01 00:00:00

abstract：:We used optical imaging of intrinsic signals to study the large-scale organization of ferret auditory cortex in response to complex sounds. Cortical responses were collected during continuous stimulation by sequences of sounds with varying frequency, period, or interaural level differences. We used a set of stimuli th...

journal_title：Journal of neurophysiology

authors： Nelken I,Bizley JK,Nodal FR,Ahmed B,King AJ,Schnupp JW

更新日期：2008-04-01 00:00:00

abstract：:Synaptic transmission throughout most of the CNS is steeply dependent on presynaptic calcium influx through the voltage-gated calcium channels Cav2.1-Cav2.3. In addition to triggering exocytosis, this calcium influx also recruits short-term synaptic plasticity. During the complex patterns of presynaptic activity that ...

journal_title：Journal of neurophysiology

authors： Ricoy UM,Frerking ME

更新日期：2014-06-15 00:00:00

abstract：:1. Areas of cerebellar cortex related to saccadic eye movements were ablated in three Macaca mulatta monkeys trained to fixate visual targets. There followed a postoperative dysmetria of saccadic eye movements which appeared to be the result of an impairment specifically within the saccadic system. 2. Convergent evide...

journal_title：Journal of neurophysiology

authors： Ritchie L

更新日期：1976-11-01 00:00:00

abstract：:Experimental evidence supports a number of mechanisms for the synaptic change that occurs with long-term potentiation (LTP) including insertion of AMPA receptors, an increase in AMPA receptor single channel conductance, unmasking silent synapses, and increases in vesicle release probability. Here we combine experiment...

journal_title：Journal of neurophysiology

authors： Holmes WR,Grover LM

更新日期：2006-09-01 00:00:00

abstract：:This paper compares the activity of hindlimb motor units from muscles mainly composed of fast-twitch muscle fibers (medial and lateral gastrocnemius: MG/LG, tibialis anterior: TA) to motor units from a muscle mainly composed of slow-twitch muscle fibers (soleus: SOL) during unrestrained walking in the conscious rat. S...

journal_title：Journal of neurophysiology

authors： Gorassini M,Eken T,Bennett DJ,Kiehn O,Hultborn H

更新日期：2000-04-01 00:00:00