Contribution of intrinsic neuronal factors in the generation of cortically driven electrographic seizures.

abstract：:The buccal ganglia of Aplysia contain a central pattern generator (CPG) that organizes the rhythmic movements of the radula and buccal mass during feeding. Many of the cellular and synaptic elements of this CPG have been identified and characterized. However, the roles that specific cellular and synaptic properties pl...

journal_title：Journal of neurophysiology

authors： Susswein AJ,Hurwitz I,Thorne R,Byrne JH,Baxter DA

更新日期：2002-05-01 00:00:00

abstract：:Since sensory systems operate with a finite quantity of processing resources, an animal would benefit from prioritizing processing of sensory stimuli within a time window that is expected to provide key information. This behavioral manifestation of such prioritization is known as attention. Here, we investigate attent...

journal_title：Journal of neurophysiology

authors： Lee CCY,Clifford CWG,Arabzadeh E

更新日期：2019-03-01 00:00:00

abstract：:Substance P initiates locomotion when injected in the brain stem of mammals. This study examined the possible role of this peptide on the supraspinal locomotor command system in lampreys. Substance P was bath applied or locally injected into an in vitro isolated brain stem, and the effects of the drug were examined on...

journal_title：Journal of neurophysiology

authors： Brocard F,Bardy C,Dubuc R

更新日期：2005-04-01 00:00:00

abstract：:Older adults are at a high risk of falls, and most falls occur during locomotor activities like walking. This study aimed to improve our understanding of changes in neuromuscular control associated with increased risk of falls in older adults in the presence of dynamic balance challenges during walking. Motor module (...

journal_title：Journal of neurophysiology

authors： Allen JL,Franz JR

更新日期：2018-11-01 00:00:00

abstract：:Based on the findings of the preceding paper, it is known that auditory and visual signals have been translated into common coordinates at the level of the superior colliculus (SC) and share a motor circuit involved in the generation of saccadic eye movements. It is not known, however, whether the translation of senso...

journal_title：Journal of neurophysiology

authors： Jay MF,Sparks DL

更新日期：1987-01-01 00:00:00

abstract：:The objective of this project was to examine the influence of stimulus waveform and frequency on extracellular stimulation of neurons with their cell bodies near the electrode (local cells) and fibers of passage in the CNS. Detailed computer-based models of CNS cells and axons were developed that accurately reproduced...

journal_title：Journal of neurophysiology

authors： McIntyre CC,Grill WM

更新日期：2002-10-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) are known to regulate axonal refinement and dendritic branching. However, because NMDARs are abundantly present as tri-heteromers (e.g., NR1/NR2A/NR2B) during development, the precise role of the individual subunits NR2A and NR2B in these processes has not been elucidated. Ventr...

journal_title：Journal of neurophysiology

authors： Sepulveda FJ,Bustos FJ,Inostroza E,Zúñiga FA,Neve RL,Montecino M,van Zundert B

更新日期：2010-04-01 00:00:00

abstract：:1. Axonal transection triggers a cascade of pathological processes that frequently lead to the degeneration of the injured neuron. It is generally believed that the degenerative process is triggered by an overwhelming influx of calcium through the cut end of the axon. 2. Theoretical considerations and indirect observa...

journal_title：Journal of neurophysiology

authors： Ziv NE,Spira ME

更新日期：1995-12-01 00:00:00

abstract：:1. The responses of single neurons in the primary somatosensory cortex of the cat to brief air-pulse stimuli were quantitatively examined. These controlled natural stimuli activated almost exclusively rapidly adapting hair units which, on systematic movement of the stimulus through the receptive field, gave unit-respo...

journal_title：Journal of neurophysiology

authors： Laskin SE,Spencer WA

更新日期：1979-07-01 00:00:00

abstract：:Mechanosensory neurons exhibit a wide range of dynamic changes in response, including rapid and slow adaptation. In addition to mechanical factors, electrical processes may also contribute to sensory adaptation. We have investigated adaptation of afferent neurons in the stick insect femoral chordotonal organ (fCO). Th...

journal_title：Journal of neurophysiology

authors： DiCaprio RA,Wolf H,Büschges A

更新日期：2002-11-01 00:00:00

abstract：:Peroneal motoneurons were recorded intracellularly in anesthetized cats during sustained submaximal contractions of peroneus brevis muscle (PB) elicited by repetitive electrical stimulation of motor axons in the distal portion of cut ventral root filaments. Mechanical stimulation of the territory innervated by the sup...

journal_title：Journal of neurophysiology

authors： Perrier JF,Lamotte D'Incamps B,Kouchtir-Devanne N,Jami L,Zytnicki D

更新日期：2000-06-01 00:00:00

abstract：:The stress hormone corticosterone increases the amplitude of the slow afterhyperpolarization (sAHP) in CA1 pyramidal neurons, without affecting resting membrane potential, input resistance, or action potential characteristics. We here examined how corticosterone affects these properties in the basolateral amygdala (BL...

journal_title：Journal of neurophysiology

authors： Liebmann L,Karst H,Sidiropoulou K,van Gemert N,Meijer OC,Poirazi P,Joëls M

更新日期：2008-02-01 00:00:00

abstract：:Response properties of cells in the infragranular layers of cortical area 17 of the cat were examined in the absence of input from supragranular layers. Supragranular activity was silenced either reversibly by cooling the surface of cortex or permanently by making a cryogenic lesion of the supragranular layers. Visual...

journal_title：Journal of neurophysiology

authors： Schwark HD,Malpeli JG,Weyand TG,Lee C

更新日期：1986-10-01 00:00:00

abstract：:Converging inputs to the entorhinal cortex from the piriform cortex and medial septum: facilitation and current source density analysis. J. Neurophysiol. 78: 2602-2615, 1997. The entorhinal cortex receives sensory inputs from the piriform cortex and modulatory inputs from the medial septum. To examine short-term synap...

journal_title：Journal of neurophysiology

authors： Chapman CA,Racine RJ

更新日期：1997-11-01 00:00:00

abstract：:Studies on generalization show the nature of how learning is encoded in the brain. Previous studies have shown rather limited generalization of dynamics learning across changes in movement direction, a finding that is consistent with the idea that learning is primarily local. In contrast, studies show a broader patter...

journal_title：Journal of neurophysiology

authors： Mattar AA,Ostry DJ

更新日期：2010-07-01 00:00:00

abstract：:To investigate the nature of the visuomotor transformation, previous studies have used pointing tasks and examined how adaptation to a spatially localized mismatch between vision and proprioception generalizes across the workspace. Whereas some studies found extensive spatial generalization of single-point remapping, ...

journal_title：Journal of neurophysiology

authors： Malfait N,Henriques DY,Gribble PL

更新日期：2008-01-01 00:00:00

abstract：:A single bout of aerobic exercise improves executive function; however, the mechanism for the improvement remains unclear. One proposal asserts that an exercise-mediated increase in cerebral blood flow (CBF) enhances the efficiency of executive-related cortical structures. To examine this, participants completed separ...

journal_title：Journal of neurophysiology

authors： Tari B,Vanhie JJ,Belfry GR,Shoemaker JK,Heath M

更新日期：2020-09-01 00:00:00

abstract：:We examined how subjects plan speeded reaching movements when the precise target of the movement is not known at movement onset. Before each reach, subjects were given only a probability distribution on possible target positions. Only after completing part of the movement did the actual target appear. In separate expe...

journal_title：Journal of neurophysiology

authors： Hudson TE,Maloney LT,Landy MS

更新日期：2007-11-01 00:00:00

abstract：:How does the motor system choose the speed for any given movement? Many current models assume a process that finds the optimal balance between the costs of moving fast and the rewards of achieving the goal. Here, we show that such models also need to take into account a prior representation of preferred movement speed...

journal_title：Journal of neurophysiology

authors： Hammerbeck U,Yousif N,Greenwood R,Rothwell JC,Diedrichsen J

更新日期：2014-01-01 00:00:00

abstract：:Thalamocortical neurons integrate sensory and cortical activity and are regulated by input from inhibitory neurons in the thalamic reticular nucleus. Evidence suggests that during bursts of action potentials, dendritic calcium transients are seen throughout the dendritic tree of thalamocortical cells. Here, we review ...

journal_title：Journal of neurophysiology

authors： Hulme SR,Connelly WM

更新日期：2014-11-01 00:00:00

abstract：:Dual whole-cell patch clamp recordings from the soma and dendrites of CA1 pyramidal neurons located in hippocampal slices of adult rats were used to examine the potential mechanisms of phase precession. To mimic phasic synaptic input, 5-Hz sine wave current injections were simultaneously delivered both to the soma and...

journal_title：Journal of neurophysiology

authors： Magee JC

更新日期：2001-07-01 00:00:00

abstract：:1. We have studied the physiology of sensory neurons innervating skin of the rat hindlimb, in three groups of animals: 1) normal animals; 2) animals in which the sural nerve (Sn) had regenerated to its original cutaneous target; and 3) animals in which the gastrocnemius muscle nerve (Gn) had previously been cut and cr...

journal_title：Journal of neurophysiology

authors： Lewin GR,McMahon SB

更新日期：1991-10-01 00:00:00

abstract：:When speed changes during locomotion, both temporal and spatial parameters of the pattern must adjust. Moreover, at slow speeds the step-to-step pattern becomes increasingly variable. The objectives of the present study were to assess if the spinal locomotor network adjusts both temporal and spatial parameters from sl...

journal_title：Journal of neurophysiology

authors： Dambreville C,Labarre A,Thibaudier Y,Hurteau MF,Frigon A

更新日期：2015-08-01 00:00:00

abstract：:A popular theory is that the cerebellum functions as a timer for clocking motor events (e.g., initiation, termination). Consistent with this idea, cerebellar patients have been reported to show greater deficits during hand movements that repeatedly start and stop (i.e., discontinuous movements) compared with continuou...

journal_title：Journal of neurophysiology

authors： Bo J,Block HJ,Clark JE,Bastian AJ

更新日期：2008-11-01 00:00:00

abstract：:The effects of deep brain stimulation (DBS) on balance in people with Parkinson's disease (PD) are not well established. This study examined whether DBS randomized to the subthalamic nucleus (STN; n = 11) or globus pallidus interna (GPi; n = 10) improved compensatory stepping to recover balance after a perturbation. T...

journal_title：Journal of neurophysiology

authors： St George RJ,Carlson-Kuhta P,King LA,Burchiel KJ,Horak FB

更新日期：2015-09-01 00:00:00

abstract：:Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of long-term synaptic plasticity in layer 2/3 of the visual cortex at the end of its critical period in rats. However, the cellular and molecular mechanisms remain unclear. Since inhibitory influence is crucial in the induction of synaptic plasticity, the ef...

journal_title：Journal of neurophysiology

authors： Jang HJ,Cho KH,Park SW,Kim MJ,Yoon SH,Rhie DJ

更新日期：2012-01-01 00:00:00

abstract：:Extracellular discharges from single neurons in the internal segment of the globus pallidus (GPi) were recorded and analyzed for rate changes associated with visually guided forearm rotations to four different targets. We sought to examine how GPi neurons contribute to movement preparation and execution. Unit discharg...

journal_title：Journal of neurophysiology

authors： Gdowski MJ,Miller LE,Parrish T,Nenonene EK,Houk JC

更新日期：2001-02-01 00:00:00

abstract：:To further understand the excitatory effects of motoneurons on spinal network function, we investigated the entrainment of disinhibited rhythms by ventral root (VR) stimulation in the neonatal mouse spinal cord. A brief train of stimuli applied to a VR triggered bursting reliably in 31/32 experiments. The same roots t...

journal_title：Journal of neurophysiology

authors： Bonnot A,Chub N,Pujala A,O'Donovan MJ

更新日期：2009-06-01 00:00:00

abstract：:1. The capacity for judging the location of an object relative to the body (egocentric localization) was assessed in cats by measuring the landing position attained when the cat jumped toward a platform viewed from a known distance. 2. Normal cats and kittens land at center of the platform when using one eye or both. ...

journal_title：Journal of neurophysiology

authors： Olson CR

更新日期：1980-03-01 00:00:00

abstract：:Neuroimaging studies in stroke survivors have suggested that adaptive plasticity occurs following stroke. However, the complex temporal dynamics of neural reorganization after injury make the interpretation of functional imaging studies equivocal. In the present study in adult squirrel monkeys, intracortical microstim...

journal_title：Journal of neurophysiology

authors： Eisner-Janowicz I,Barbay S,Hoover E,Stowe AM,Frost SB,Plautz EJ,Nudo RJ

更新日期：2008-09-01 00:00:00