Cooperation of muscle and cutaneous afferents in the feedback of contraction to peroneal motoneurons.

abstract：:To clarify the role of cholinergic inputs to the intermediate layer of the superior colliculus (SC), we examined the effect of microinjection of nicotine into the SC on visually guided saccades in macaque monkeys. After injection of 0.4-2 microl of 1-100 mM nicotine into the SC, frequency of extremely short latency sa...

journal_title：Journal of neurophysiology

authors： Aizawa H,Kobayashi Y,Yamamoto M,Isa T

更新日期：1999-09-01 00:00:00

abstract：:1. Two monkeys were trained to grasp an object between the thumb and index finger and lift it to a vertical distance of 12-25 mm. Up to 12 different conditions defined by different combinations of object weights (15, 65, and 115 g) and four surface textures (oiled metal, smooth metal, fine and coarse sandpaper) were u...

journal_title：Journal of neurophysiology

authors： Picard N,Smith AM

更新日期：1992-11-01 00:00:00

abstract：:The basal forebrain plays important roles in arousal, learning, and memory by stimulating cortical activation characterized by rhythmic slow theta and high-frequency beta-gamma activities. Although cholinergic neurons play a significant part in these roles, other, including GABAergic, neurons appear to contribute. Usi...

journal_title：Journal of neurophysiology

authors： Manns ID,Alonso A,Jones BE

更新日期：2003-02-01 00:00:00

abstract：:Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matc...

journal_title：Journal of neurophysiology

authors： Metzler-Wilson K,Toma K,Sammons DL,Mann S,Jurovcik AJ,Demidova O,Wilson TE

更新日期：2015-09-01 00:00:00

abstract：:Animal survival in the forest, and human success on the sports field, often depend on the ability to seize a target on the fly. All bodies fall at the same rate in the gravitational field, but the corresponding retinal motion varies with apparent viewing distance. How then does the brain predict time-to-collision unde...

journal_title：Journal of neurophysiology

authors： Miller WL,Maffei V,Bosco G,Iosa M,Zago M,Macaluso E,Lacquaniti F

更新日期：2008-04-01 00:00:00

abstract：:The neuronal mechanisms that contribute to tactile perception were studied using single-unit recordings from the cutaneous hand representation of primate primary (S1) and secondary (S2) somatosensory cortex. This study followed up on our recent observation that S1 and S2 neurons developed a sustained change in dischar...

journal_title：Journal of neurophysiology

authors： Meftah el-M,Bourgeon S,Chapman CE

更新日期：2009-05-01 00:00:00

abstract：:Long-term potentiation (LTP) of C-fiber-evoked field potentials in spinal dorsal horn may be relevant to pathological pain. Our previous work has shown that the late phase of the spinal LTP is protein synthesis-dependent. Considerable evidence has accumulated that dopamine D1/D5 receptors are important for late-phase ...

journal_title：Journal of neurophysiology

authors： Yang HW,Zhou LJ,Hu NW,Xin WJ,Liu XG

更新日期：2005-08-01 00:00:00

abstract：:In the preceding report, we observed that tail-shock-induced sensitization of tail-elicited siphon withdrawal reflex (TSW) of Aplysia was expressed ipsilaterally but that dishabituation induced by an identical tail shock was expressed bilaterally. Here we examined the mechanisms of this differential lateralization. We...

journal_title：Journal of neurophysiology

authors： Bristol AS,Marinesco S,Carew TJ

更新日期：2004-02-01 00:00:00

abstract：:The cerebellum was historically considered a brain region dedicated to motor control, but it has become clear that it also contributes to sensory processing, particularly when sensory discrimination is required. Prior work, for example, has demonstrated a cerebellar contribution to sensory discrimination in the visual...

journal_title：Journal of neurophysiology

authors： Dahlem K,Valko Y,Schmahmann JD,Lewis RF

更新日期：2016-05-01 00:00:00

abstract：:1. Monkeys were trained to react to an arm perturbation according to an instruction delivered prior to the perturbation. There were two possible instructions (push or pull), and monkeys learned to respond accordingly regardless of the direction (push or pull) of the triggering perturbation. 2. Pyramidal tract neurons ...

journal_title：Journal of neurophysiology

authors： Evarts EV,Tanji J

更新日期：1976-09-01 00:00:00

abstract：:Astrocyte-derived lactate supports pathologically enhanced neuronal metabolism, but its role under physiological conditions is still a matter of debate. Here, we determined the contribution of astrocytic neuronal lactate shuttle for maintenance of ion homeostasis and energy metabolism. We tested for the effects of α-c...

journal_title：Journal of neurophysiology

authors： Angamo EA,Rösner J,Liotta A,Kovács R,Heinemann U

更新日期：2016-11-01 00:00:00

abstract：:The primate superior colliculus (SC) is causally involved in microsaccade generation. Moreover, visually responsive SC neurons across this structure's topographic map, even at peripheral eccentricities much larger than the tiny microsaccade amplitudes, exhibit significant modulations of evoked response sensitivity whe...

journal_title：Journal of neurophysiology

authors： Khademi F,Chen CY,Hafed ZM

更新日期：2020-06-01 00:00:00

abstract：:Sustained oscillations of 13-18 Hz were observed in local field potentials (LFPs) in the cerebellar cortex of a behaving monkey. These oscillations, which appeared to be generated in the granular cell layer, were particularly prominent in the paramedian lobule. The oscillatory activity decreased during drowsiness or e...

journal_title：Journal of neurophysiology

authors： Pellerin JP,Lamarre Y

更新日期：1997-12-01 00:00:00

abstract：:Primary afferent fibers from the electroreceptors of mormyrid electric fish use a latency code to signal the intensity of electrical current evoked by the fish's own electric organ discharge (EOD). The afferent fibers terminate centrally in the deep and superficial granular layers of the electrosensory lobe with morph...

journal_title：Journal of neurophysiology

authors： Zhang J,Han VZ,Meek J,Bell CC

更新日期：2007-03-01 00:00:00

abstract：:A classical question in neuroscience is which features of a stimulus or of an action are represented in brain activity. When several features are interdependent either at a given point in time or at distinct points in time, neural activity related to one feature appears to be correlated with other features. Thus techn...

journal_title：Journal of neurophysiology

authors： Stark E,Drori R,Abeles M

更新日期：2006-03-01 00:00:00

abstract：:At many glutamatergic synapses, non-N-methyl-d-aspartate (NMDA) and NMDA receptors are coexpressed postsynaptically. In the mammalian retina, glutamatergic rod bipolar cells are presynaptic to two rod amacrine cells (AII and A17) that constitute dyad postsynaptic partners opposite each presynaptic active zone. Whereas...

journal_title：Journal of neurophysiology

authors： Zhou Y,Tencerová B,Hartveit E,Veruki ML

更新日期：2016-01-01 00:00:00

abstract：:Sensory cortical neurons display substantial receptive field dynamics during and after persistent sensory drive. Because a cell's response properties are determined by the inputs it receives, receptive field dynamics are likely to involve changes in the relative efficacy of different inputs to the cell. To test this h...

journal_title：Journal of neurophysiology

authors： Kohn A,Metz C,Tommerdahl MA,Whitsel BL

更新日期：2002-12-01 00:00:00

abstract：:Responses of cat striate cortical cells to a drifting sinusoidal grating were modified by the superimposition of a second, perturbing grating (PG) that did not excite the cell when presented alone. One consequence of the presence of a PG was a shift in the tuning curves. The orientation tuning of all 41 cells exposed ...

journal_title：Journal of neurophysiology

authors： Kabara JF,Bonds AB

更新日期：2001-12-01 00:00:00

abstract：:The dorsolateral pontine nucleus (DLPN) and nucleus reticularis tegmenti pontis (NRTP) comprise obligatory links in the cortico-ponto-cerebellar system supporting smooth pursuit eye movements. We examined the response properties of DLPN and rNRTP neurons during step-ramp smooth pursuit of a small target moving across ...

journal_title：Journal of neurophysiology

authors： Ono S,Das VE,Economides JR,Mustari MJ

更新日期：2005-01-01 00:00:00

abstract：:Cacna1a encodes the pore-forming α1A subunit of CaV2.1 voltage-dependent calcium channels, which regulate neuronal excitability and synaptic transmission. Purkinje cells in the cortex of cerebellum abundantly express these CaV2.1 channels. Here, we show that homozygous tottering (tg) mice, which carry a loss-of-functi...

journal_title：Journal of neurophysiology

authors： de Oude NL,Hoebeek FE,Ten Brinke MM,de Zeeuw CI,Boele HJ

更新日期：2020-12-16 00:00:00

abstract：:Frequent gait modifications are often required to navigate our world. These can involve long or wide steps or changes in direction. People generally prefer to minimize the motor cost (or effort) of a movement, although with changes in gait this is not always possible. The decision of when and where to shift gaze is cr...

journal_title：Journal of neurophysiology

authors： Domínguez-Zamora FJ,Marigold DS

更新日期：2019-07-01 00:00:00

abstract：:Nicotine evokes pain in the skin and oral mucosa and excites a subpopulation of cutaneous nociceptors, but little is known about the central transmission of chemogenic pain. We have investigated the responses of lumbar spinal wide dynamic range (WDR)-type dorsal horn neurons to intracutaneous (ic) microinjection of ni...

journal_title：Journal of neurophysiology

authors： Jinks SL,Carstens E

更新日期：1999-12-01 00:00:00

abstract：:Cognitive and motor deficits associated with language and speech are seen in humans harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are thought to reside in structural abnormalities distributed across systems important for language and motor learning including the cerebral cortex, basal...

journal_title：Journal of neurophysiology

authors： Miller JE,Spiteri E,Condro MC,Dosumu-Johnson RT,Geschwind DH,White SA

更新日期：2008-10-01 00:00:00

abstract：:Contusion-type injuries to the spinal cord are characterized by tissue loss and disruption of spinal pathways. Midcervical spinal cord injuries impair the function of respiratory muscles and may contribute to significant respiratory complications. This study systematically assessed the impact of a 100-kDy unilateral C...

journal_title：Journal of neurophysiology

authors： Rana S,Sieck GC,Mantilla CB

更新日期：2017-02-01 00:00:00

abstract：:This paper compares the activity of hindlimb motor units from muscles mainly composed of fast-twitch muscle fibers (medial and lateral gastrocnemius: MG/LG, tibialis anterior: TA) to motor units from a muscle mainly composed of slow-twitch muscle fibers (soleus: SOL) during unrestrained walking in the conscious rat. S...

journal_title：Journal of neurophysiology

authors： Gorassini M,Eken T,Bennett DJ,Kiehn O,Hultborn H

更新日期：2000-04-01 00:00:00

abstract：:Generalization is a fundamental aspect of behavior, allowing for the transfer of knowledge from one context to another. The details of this transfer are thought to reveal how the brain represents what it learns. Generalization has been a central focus in studies of sensorimotor adaptation, and its pattern has been wel...

journal_title：Journal of neurophysiology

authors： McDougle SD,Bond KM,Taylor JA

更新日期：2017-07-01 00:00:00

abstract：:1. The modulation of the voltage-activated Ca2+ current by the neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFa) was investigated in dissociated central neurons from Helix aspersa using whole-cell voltage-clamp recording techniques. External Ba2+ was always used as the charge carrier in this study, and the intracellular Ca2+ c...

journal_title：Journal of neurophysiology

authors： Yakel JL

更新日期：1991-06-01 00:00:00

abstract：:Previously, an essential tremor-like phenotype has been noted in animals with a global knockout of the GABAAα1 subunit. Given the hypothesized role of the cerebellum in tremor, including essential tremor, we used transgenic mice to selectively knock out the GABAAα1 subunit from cerebellar Purkinje cells. We examined t...

journal_title：Journal of neurophysiology

authors： Nietz A,Krook-Magnuson C,Gutierrez H,Klein J,Sauve C,Hoff I,Christenson Wick Z,Krook-Magnuson E

更新日期：2020-10-01 00:00:00

abstract：:Although metabotropic glutamate receptors (mGluRs) mGluR1 and mGluR5 are often found to have similar functions, there is considerable evidence that the two receptors also serve distinct functions in neurons. In hippocampal area CA1, mGluR5 has been most strongly implicated in long-term synaptic depression (LTD), where...

journal_title：Journal of neurophysiology

authors： Volk LJ,Daly CA,Huber KM

更新日期：2006-04-01 00:00:00

abstract：:1. Intracortical microstimulation (ICMS) techniques were used to derive detailed maps of distal forelimb movement representations in primary motor cortex (area 4) of adult squirrel monkeys before and a few months after a focal ischemic infarct. 2. Infarcts caused a marked but transient deficit in use of the contralate...

journal_title：Journal of neurophysiology

authors： Nudo RJ,Milliken GW

更新日期：1996-05-01 00:00:00