Modification of response functions of cat visual cortical cells by spatially congruent perturbing stimuli.

Abstract:

:Responses of cat striate cortical cells to a drifting sinusoidal grating were modified by the superimposition of a second, perturbing grating (PG) that did not excite the cell when presented alone. One consequence of the presence of a PG was a shift in the tuning curves. The orientation tuning of all 41 cells exposed to a PG and the spatial frequency tuning of 83% of the 23 cells exposed to a PG showed statistically significant dislocations of both the response function peak and center of mass from their single grating values. As found in earlier reports, the presence of PGs suppressed responsiveness. However, reductions measured at the single grating optimum orientation or spatial frequency were on average 1.3 times greater than the suppression found at the peak of the response function modified by the presence of the PG. Much of the loss in response seen at the single grating optimum is thus a result of a shift in the tuning function rather than outright suppression. On average orientation shifts were repulsive and proportional (approximately 0.10 deg/deg) to the angle between the perturbing stimulus and the optimum single grating orientation. Shifts in the spatial frequency response function were both attractive and repulsive, resulting in an overall average of zero. For both simple and complex cells, PGs generally broadened orientation response function bandwidths. Similarly, complex cell spatial frequency response function bandwidths broadened. Simple cell spatial frequency response functions usually did not change, and those that did broadened only 4% on average. These data support the hypothesis that additional sinusoidal components in compound stimuli retune cells' response functions for orientation and spatial frequency.

journal_name

J Neurophysiol

authors

Kabara JF,Bonds AB

doi

10.1152/jn.2001.86.6.2703

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

2703-14

issue

6

eissn

0022-3077

issn

1522-1598

journal_volume

86

pub_type

杂志文章
  • Acetylcholine increases intracellular calcium of arterial chemoreceptor cells of adult cats.

    abstract::Acetylcholine increases intracellular calcium of arterial chemoreceptor cells of adult cats. J. Neurophysiol. 78: 2388-2395, 1997. Several neurotransmitters have been reported to play important roles in the chemoreception of the carotid body. Among them acetylcholine (ACh) appears to be involved in excitatory processe...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.78.5.2388

    authors: Shirahata M,Fitzgerald RS,Sham JS

    更新日期:1997-11-01 00:00:00

  • Dipole source analyses of early median nerve SEP components obtained from subdural grid recordings.

    abstract::The median nerve N20 and P22 SEP components constitute the initial response of the primary somatosensory cortex to somatosensory stimulation of the upper extremity. Knowledge of the underlying generators is important both for basic understanding of the initial sequence of cortical activation and to identify landmarks ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00116.2010

    authors: Baumgärtner U,Vogel H,Ohara S,Treede RD,Lenz FA

    更新日期:2010-12-01 00:00:00

  • Cerebellar control of saccade dynamics: contribution of the fastigial oculomotor region.

    abstract::The fastigial oculomotor region is the output by which the medioposterior cerebellum influences the generation of saccades. Recent inactivation studies reported observations suggesting an involvement in their dynamics (velocity and duration). In this work, we tested this hypothesis in the head-restrained monkey with t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01021.2014

    authors: Quinet J,Goffart L

    更新日期:2015-05-01 00:00:00

  • Respiratory-related neural assemblies in the brain stem midline.

    abstract::1. The initial objective of this study was to determine whether respiratory-related neural assemblies exist in the brain stem midline. A second goal was to seek evidence for concurrent relationships among the neurons that could generate the detected synchrony. 2. Experiments were conducted on anesthetized, paralyzed, ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.67.4.905

    authors: Lindsey BG,Hernandez YM,Morris KF,Shannon R,Gerstein GL

    更新日期:1992-04-01 00:00:00

  • Influence of biases in numerical magnitude allocation on human prosocial decision making.

    abstract::Over the past decade neuroscientific research has attempted to probe the neurobiological underpinnings of human prosocial decision making. Such research has almost ubiquitously employed tasks such as the dictator game or similar variations (i.e., ultimatum game). Considering the explicit numerical nature of such tasks...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00372.2017

    authors: Arshad Q,Nigmatullina Y,Siddiqui S,Franka M,Mediratta S,Ramachandaran S,Lobo R,Malhotra PA,Roberts RE,Bronstein AM

    更新日期:2017-12-01 00:00:00

  • Neuronal gap junctions are required for NMDA receptor-mediated excitotoxicity: implications in ischemic stroke.

    abstract::N-methyl-D-aspartate receptors (NMDARs) play an important role in cell survival versus cell death decisions during neuronal development, ischemia, trauma, and epilepsy. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all these conditions. In the developing CN...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00656.2010

    authors: Wang Y,Denisova JV,Kang KS,Fontes JD,Zhu BT,Belousov AB

    更新日期:2010-12-01 00:00:00

  • Laser-evoked potentials are graded and somatotopically organized anteroposteriorly in the operculoinsular cortex of anesthetized monkeys.

    abstract::The operculoinsular cortical region has a major role in the representation of noxious stimuli, based on functional imaging observations, clinical lesion studies, and EEG recordings of specifically pain-related laser-evoked potentials (LEPs) in humans. The source of LEPs has not been identified, and several somatic rep...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00512.2006

    authors: Baumgärtner U,Tiede W,Treede RD,Craig AD

    更新日期:2006-11-01 00:00:00

  • Expansion of afferent vestibular signals after the section of one of the vestibular nerve branches.

    abstract::The anterior branch of N. VIII was sectioned in adult frogs. Two months later the brain was isolated to record in vitro responses in the vestibular nuclei and from the abducens nerves following electric stimulation of the anterior branch of N. VIII or of the posterior canal nerve. Extra- and intracellularly recorded r...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2000.84.1.581

    authors: Goto F,Straka H,Dieringer N

    更新日期:2000-07-01 00:00:00

  • Target selection for saccadic eye movements: direction-selective visual responses in the superior colliculus.

    abstract::We investigated the role of the superior colliculus (SC) in saccade target selection in rhesus monkeys who were trained to perform a direction-discrimination task. In this task, the monkey discriminated between opposed directions of visual motion and indicated its judgment by making a saccadic eye movement to one of t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.86.5.2527

    authors: Horwitz GD,Newsome WT

    更新日期:2001-11-01 00:00:00

  • Background-induced flicker enhancement in cat retinal horizontal cells. I. Temporal and spectral properties.

    abstract::1. Dim backgrounds can enhance small-spot flicker responses of cat retinal horizontal cells by a factor of 2 or more. 2. Intracellular marking with horseradish peroxidase (HRP) reveals that this enhancement effect occurs in--but is not necessarily limited to--the cone-connected, A-type horizontal cell. 3. Flicker ampl...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.2.313

    authors: Pflug R,Nelson R,Ahnelt PK

    更新日期:1990-08-01 00:00:00

  • Receptive-field properties of neurons in binocular and monocular segments of striate cortex in cats raised with binocular lid suture.

    abstract::1. We studied the receptive fields of 171 striate cortical neurons from 17 cats raised with binocular lid suture. Of these, 102 fields were within 10 degrees of the area centralis and the remaining 69 were at least 38 degrees from the vertical meridian. 2. Based on their different response properties, cells were divid...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1978.41.2.322

    authors: Watkins DW,Wilson JR,Sherman SM

    更新日期:1978-03-01 00:00:00

  • Encoding of binocular disparity by simple cells in the cat's visual cortex.

    abstract::1. Spatiotemporal receptive fields (RFs) for left and right eyes were studied for simple cells in the cat's striate cortex to examine the idea that stereoscopic depth information is encoded via structural differences of RFs between the two eyes. Traditional models are based on neurons that possess matched RF profiles ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.75.5.1779

    authors: Ohzawa I,DeAngelis GC,Freeman RD

    更新日期:1996-05-01 00:00:00

  • Eye position effects in monkey cortex. I. Visual and pursuit-related activity in extrastriate areas MT and MST.

    abstract::We studied the effect of eye position on visual and pursuit-related activity in neurons in the superior temporal sulcus of the macaque monkey. Altogether, 109 neurons from the middle temporal area (area MT) and the medial superior temporal area (area MST) were tested for influence of eye position on their stimulus-dri...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.77.2.944

    authors: Bremmer F,Ilg UJ,Thiele A,Distler C,Hoffmann KP

    更新日期:1997-02-01 00:00:00

  • Mammalian voltage-activated calcium channel currents are blocked by Pb2+, Zn2+, and Al3+.

    abstract::1. The effects of the di- and trivalent trace metal cations, Pb2+, Zn2+, and Al3+, on voltage-activated calcium channel currents recorded from cultured rat dorsal root ganglion neurons were determined. 2. All three cations blocked transient and sustained components of the voltage-gated calcium channel currents elicite...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.71.4.1491

    authors: Büsselberg D,Platt B,Michael D,Carpenter DO,Haas HL

    更新日期:1994-04-01 00:00:00

  • The spinal control of locomotion and step-to-step variability in left-right symmetry from slow to moderate speeds.

    abstract::When speed changes during locomotion, both temporal and spatial parameters of the pattern must adjust. Moreover, at slow speeds the step-to-step pattern becomes increasingly variable. The objectives of the present study were to assess if the spinal locomotor network adjusts both temporal and spatial parameters from sl...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00419.2015

    authors: Dambreville C,Labarre A,Thibaudier Y,Hurteau MF,Frigon A

    更新日期:2015-08-01 00:00:00

  • Dendritic distributions of L-type Ca2+ and SKL channels in spinal motoneurons: a simulation study.

    abstract::Persistent inward currents are important to motoneuron excitability and firing behaviors and also have been implicated in excitotoxicity. In particular, L-type Ca2+ channels, usually located on motoneuron dendrites, play a primary role in amplification of synaptic inputs. However, recent experimental findings on L-typ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00169.2020

    authors: Mousa MH,Elbasiouny SM

    更新日期:2020-10-01 00:00:00

  • Spontaneous electrical activity and interaction of large and small cells in cardiac ganglion of the crab, Portunus sanguinolentus.

    abstract::1. Semi-isolated preparations of the nine-celled cardiac ganglion of the crab, Portunus sanguinolentus, were studied electrophysiologically, using simultaneous recording from extracellular and two or three intracellular electrodes. Nine penetrations of small cells were achieved. 2. Three large (80 x 120 micron) cells ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1979.42.4.975

    authors: Tazaki K,Cooke IM

    更新日期:1979-07-01 00:00:00

  • Cerebellar contributions to self-motion perception: evidence from patients with congenital cerebellar agenesis.

    abstract::The cerebellum was historically considered a brain region dedicated to motor control, but it has become clear that it also contributes to sensory processing, particularly when sensory discrimination is required. Prior work, for example, has demonstrated a cerebellar contribution to sensory discrimination in the visual...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00763.2015

    authors: Dahlem K,Valko Y,Schmahmann JD,Lewis RF

    更新日期:2016-05-01 00:00:00

  • Differential activation of lumbar and sacral motor pools during walking at different speeds and slopes.

    abstract::Organization of spinal motor output has become of interest for investigating differential activation of lumbar and sacral motor pools during locomotor tasks. Motor pools are associated with functional grouping of motoneurons of the lower limb muscles. Here we examined how the spatiotemporal organization of lumbar and ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00167.2019

    authors: Dewolf AH,Ivanenko YP,Zelik KE,Lacquaniti F,Willems PA

    更新日期:2019-08-01 00:00:00

  • Effects of leg pedaling on early latency cutaneous reflexes in upper limb muscles.

    abstract::The functional coupling of neural circuits between the upper and lower limbs involving rhythmic movements is of interest to both motor control research and rehabilitation science. This coupling can be detected by examining the effect of remote rhythmic limb movement on the modulation of reflex amplitude in stationary ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00774.2009

    authors: Sasada S,Tazoe T,Nakajima T,Zehr EP,Komiyama T

    更新日期:2010-07-01 00:00:00

  • Updating visual memory across eye movements for ocular and arm motor control.

    abstract::Remembered object locations are stored in an eye-fixed reference frame, so that every time the eyes move, spatial representations must be updated for the arm-motor system to reflect the target's new relative position. To date, studies have not investigated how the brain updates these spatial representations during oth...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.90599.2008

    authors: Thompson AA,Henriques DY

    更新日期:2008-11-01 00:00:00

  • Plasticity in the mediodorsal thalamo-prefrontal cortical transmission in behaving mice.

    abstract::We studied changes in thalamo-prefrontal cortical transmission in behaving mice following both low-frequency stimulation of the mediodorsal thalamus (MD) and during extinction of a conditioned fear response. Electrical stimulation of the MD induces a field potential in the medial prefrontal cortex (mPFC) characterized...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.82.5.2827

    authors: Herry C,Vouimba RM,Garcia R

    更新日期:1999-11-01 00:00:00

  • Genetic variants of the NMDA receptor influence cortical excitability and plasticity in humans.

    abstract::N-methyl-d-aspartate (NMDA) receptors play crucial roles in glutamate-mediated synaptic transmission and plasticity and are involved in a variety of brain functions. Specific single nucleotide polymorphisms (SNPs) in the genes encoding NMDA receptor subunits have been associated with some neuropsychiatric disorders in...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00318.2011

    authors: Mori F,Ribolsi M,Kusayanagi H,Siracusano A,Mantovani V,Marasco E,Bernardi G,Centonze D

    更新日期:2011-10-01 00:00:00

  • Long-term enhancement of synchronized oscillations by adrenergic receptor activation in the olfactory bulb.

    abstract::The noradrenergic system is widely thought to be important for associative learning in the olfactory system through actions in the first processing structure, the main olfactory bulb (MOB). Here, we used extracellular local field potential (LFP) and patch-clamp recordings in rat MOB slices to examine norepinephrine (N...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01324.2007

    authors: Gire DH,Schoppa NE

    更新日期:2008-04-01 00:00:00

  • Effects of kappa opioid receptor-selective agonists on responses of pelvic nerve afferents to noxious colorectal distension.

    abstract::The aim of this study was to examine the effects of kappa-opioid receptor selective agonists on responses of mechanosensitive afferent fibers in the pelvic nerve. Single-fiber recordings were made from pelvic nerve afferents in the decentralized S1 dorsal root of the rat. A total of 572 afferent fibers in the S1 dorsa...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.78.2.1003

    authors: Su X,Sengupta JN,Gebhart GF

    更新日期:1997-08-01 00:00:00

  • Activity-related calcium dynamics in motoneurons of the nucleus hypoglossus from mouse.

    abstract::A quantitative analysis of activity-related calcium dynamics was performed in motoneurons of the nucleus hypoglossus in the brain stem slice preparation from mouse by simultaneous patch-clamp and microfluorometric calcium measurements. Motoneurons were analyzed under in vitro conditions that kept them in a functionall...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.82.6.2936

    authors: Lips MB,Keller BU

    更新日期:1999-12-01 00:00:00

  • Retinogeniculate synaptic properties controlling spike number and timing in relay neurons.

    abstract::Retinal ganglion cells (RGC) transmit visual signals to thalamocortical relay neurons in the lateral geniculate nucleus via retinogeniculate synapses. Relay neuron spike patterns do not simply reflect those of RGCs, but the mechanisms controlling this transformation are not well understood. We therefore examined synap...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00562.2003

    authors: Blitz DM,Regehr WG

    更新日期:2003-10-01 00:00:00

  • Homomeric and heteromeric ion channels formed from the kainate-type subunits GluR6 and KA2 have very small, but different, unitary conductances.

    abstract::1. Patch-clamp methods were used to study recombinant glutamate receptor (GluR) ion channels expressed in human embryonic kidney cells (HEK 293) after transfection of the cells with cDNAs encoding kainate (KA)-type GluR subunits. Cells were transiently or stably transfected with the fully edited (R) version of GluR6 o...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.76.1.510

    authors: Howe JR

    更新日期:1996-07-01 00:00:00

  • Animal-to-animal variability in the phasing of the crustacean cardiac motor pattern: an experimental and computational analysis.

    abstract::The cardiac ganglion (CG) of Homarus americanus is a central pattern generator that consists of two oscillatory groups of neurons: "small cells" (SCs) and "large cells" (LCs). We have shown that SCs and LCs begin their bursts nearly simultaneously but end their bursts at variable phases. This variability contrasts wit...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01010.2012

    authors: Williams AH,Kwiatkowski MA,Mortimer AL,Marder E,Zeeman ML,Dickinson PS

    更新日期:2013-05-01 00:00:00

  • Synaptic organization of the tectal-facial pathways in the cat. I. Synaptic potentials following collicular stimulation.

    abstract::1. The synaptic pathways underlying tectal influence over pinna movements were studied using an acute electrophysiological approach. Under pentobarbital anesthesia, postsynaptic potentials were recorded intracellularly in antidromically identified, cat facial motoneurons following electrical stimulation of the superio...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.2.769

    authors: Vidal PP,May PJ,Baker R

    更新日期:1988-08-01 00:00:00