Analysis of left ventricular function from multiple gated acquisition cardiac blood pool imaging. Comparison to contrast angiography.

abstract：BACKGROUND:Alpha-linolenic acid may protect against cardiovascular disease. We examined the association between adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction (MI) in a population-based case-control study in Costa Rica. METHODS AND RESULTS:The 482 case patients with a first nonfatal acute...

journal_title：Circulation

authors： Baylin A,Kabagambe EK,Ascherio A,Spiegelman D,Campos H

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Digoxin is commonly prescribed in symptomatic paroxysmal atrial fibrillation (AF) but has never been evaluated in this condition. METHODS AND RESULTS:From a multicenter registry, 43 representative patients with frequent symptomatic AF episodes were recruited into a randomized, double-blind crossover compari...

journal_title：Circulation

authors： Murgatroyd FD,Gibson SM,Baiyan X,O'Nunain S,Poloniecki JD,Ward DE,Malik M,Camm AJ

更新日期：1999-06-01 00:00:00

abstract：:Labetalol was administered to six hypertensive subjects in increasing doses for seven days. A decrease in both supine and standing arterial pressure and heart rate was observed with no change in cardiac output and few side effects. Exercise tolerance was unaltered by the drug, but the heart rate and arterial pressure ...

journal_title：Circulation

authors： Mehta J,Cohn JN

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Previous studies have reported an association between chronic Helicobacter pylori infection and ischemic heart disease. However, it is not clear whether this association is really due to the virulence of the bacterium or is merely the result of confounding factors (in particular, age and social class). METH...

journal_title：Circulation

authors： Pasceri V,Cammarota G,Patti G,Cuoco L,Gasbarrini A,Grillo RL,Fedeli G,Gasbarrini G,Maseri A

更新日期：1998-05-05 00:00:00

abstract：:It has been suggested that the rate of left ventricular (LV) relaxation is related to the inotropic state, end-systolic fiber length and peak LV pressure, but little information is available regarding the rate of LV relaxation in patients with coronary artery disease (CAD) and LV dysfunction. To assess the rate of LV ...

journal_title：Circulation

authors： Papapietro SE,Coghlan HC,Zissermann D,Russell RO Jr,Rackley CE,Rogers WJ

更新日期：1979-05-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH) is a structural adaptation of the heart and is a response to increased hemodynamic and metabolic demands, which are most commonly caused by systemic hypertension. LVH induced by hypertension is associated with reduced myocardial compliance, structural alterations, and changes in coro...

journal_title：Circulation

authors： Frishman WH,Skolnick AE,Strom JA

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Sporadic aortic aneurysm and dissection (AAD), caused by progressive aortic smooth muscle cell (SMC) loss and extracellular matrix degradation, is a highly lethal condition. Identifying mechanisms that drive aortic degeneration is a crucial step in developing an effective pharmacologic treatment to prevent d...

journal_title：Circulation

authors： Luo W,Wang Y,Zhang L,Ren P,Zhang C,Li Y,Azares AR,Zhang M,Guo J,Ghaghada KB,Starosolski ZA,Rajapakshe K,Coarfa C,Li Y,Chen R,Fujiwara K,Abe JI,Coselli JS,Milewicz DM,LeMaire SA,Shen YH

更新日期：2020-01-07 00:00:00

abstract：BACKGROUND:Pain triggers a homeostatic alarm reaction to injury. It remains unknown, however, whether nociceptive signaling activated by ischemia is relevant for progenitor cells (PC) release from bone marrow. To this end, we investigated the role of the neuropeptide substance P (SP) and cognate neurokinin 1 (NK1) noci...

journal_title：Circulation

authors： Amadesi S,Reni C,Katare R,Meloni M,Oikawa A,Beltrami AP,Avolio E,Cesselli D,Fortunato O,Spinetti G,Ascione R,Cangiano E,Valgimigli M,Hunt SP,Emanueli C,Madeddu P

更新日期：2012-04-10 00:00:00

abstract：BACKGROUND:Heat shock proteins (HSPs) are well known for their ability to "protect" the structure and function of native macromolecules, particularly as they traffic across membranes. Considering the role of key mitochondrial proteins in apoptosis and the known antiapoptotic effects of HSP27 and HSP72, we postulated th...

journal_title：Circulation

authors： Kirchhoff SR,Gupta S,Knowlton AA

更新日期：2002-06-18 00:00:00

abstract：BACKGROUND:Early intervention with thrombolytic agents has been shown unequivocally to reduce mortality after acute myocardial infarction. Presently used agents have disadvantages such as short half-life, immunogenicity, hypotension, and bleeding complications. Therefore, there is a need to develop improved thrombolyti...

journal_title：Circulation

authors： Robinson JH,Browne MJ,Carey JE,Chamberlain PD,Chapman CG,Cronk DW,Dodd I,Entwisle C,Esmail AF,Kalindjian SB

更新日期：1992-08-01 00:00:00

abstract：:Threshold bipolar pacing was performed from one of 12 selected atrial sites with temporary implanted electrodes in 69 patients following open-heart surgery in order to study P wave polarity and morphology and the P-R interval during paced ectopic atrial rhythms. A negative P wave was recorded in lead I only with paci...

journal_title：Circulation

authors： MacLean WA,Karp RB,Kouchoukos NT,James TN,Waldo AL

更新日期：1975-09-01 00:00:00

abstract：:We used Doppler echocardiography to quantitate the changes in intracardiac blood flow velocities and right and left ventricular stroke volumes in 80 normal human fetuses from 19 to 40 weeks gestation. Blood flow velocity spectra across the aortic, pulmonary, tricuspid, and mitral valves were digitized to obtain peak v...

journal_title：Circulation

authors： Kenny JF,Plappert T,Doubilet P,Saltzman DH,Cartier M,Zollars L,Leatherman GF,St John Sutton MG

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:Mild and moderate functional ischemic mitral insufficiency present at the time of surgical revascularization present clinical uncertainty. It is unclear whether the relatively poor outcomes in this cohort are dependent on valvular function or related to left ventricular dysfunction. The purpose of this study...

journal_title：Circulation

authors： Grossi EA,Crooke GA,DiGiorgi PL,Schwartz CF,Jorde U,Applebaum RM,Ribakove GH,Galloway AC,Grau JB,Colvin SB

更新日期：2006-07-04 00:00:00

abstract：BACKGROUND:Magnetic resonance (MR) phase-shift velocity mapping is an established method for measurement of nonturbulent intravascular flow. Shortening the echo time of the MR sequence to 3.6 msec allowed application of the technique to turbulent jet flow. The objective of this study was validation of MR jet velocity m...

journal_title：Circulation

authors： Kilner PJ,Manzara CC,Mohiaddin RH,Pennell DJ,Sutton MG,Firmin DN,Underwood SR,Longmore DB

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Studies have consistently shown that ventricular tachycardia (VT) and sudden cardiac death (SCD) complicate the long-term outcome after tetralogy of Fallot repair, yet the diagnostic and predictive value of electrophysiological testing in this population is uncertain. METHODS AND RESULTS:A multicenter cohor...

journal_title：Circulation

authors： Khairy P,Landzberg MJ,Gatzoulis MA,Lucron H,Lambert J,Marçon F,Alexander ME,Walsh EP

更新日期：2004-04-27 00:00:00

abstract：:Direct examination of the aortic orifice at the level of the aortic valves (aortic valvular orifice area, AVOA) in the short-axis plane was performed with a 3 MHz two-dimensional pulsed Doppler echocardiographic apparatus. The AVOA was mapped with the Doppler gate to detect or rule out the presence of a regurgitant ao...

journal_title：Circulation

authors： Veyrat C,Lessana A,Abitbol G,Ameur A,Benaim R,Kalmanson D

更新日期：1983-11-01 00:00:00

abstract：:The acute coronary hemodynamic and metabolic effects of intravenous dipyridamole were studied in 13 patients. Total left ventricular (LV), anterior (supplied by the left anterior descending coronary artery) and inferior (supplied by circumflex and right coronary arteries) regional flows and metabolic responses were as...

journal_title：Circulation

authors： Feldman RL,Nichols WW,Pepine CJ,Conti CR

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:For patients with acute dilated cardiomyopathy, definition of prognosis and of clinical features predictive of outcome is particularly important due to the availability of cardiac transplantation and other innovative treatment strategies. METHODS AND RESULTS:We reviewed our experience with 24 children under...

journal_title：Circulation

authors： Matitiau A,Perez-Atayde A,Sanders SP,Sluysmans T,Parness IA,Spevak PJ,Colan SD

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase (COX)-2 contributes to vascular smooth muscle cell (VSMC) proliferation induced by tumor necrosis factor (TNF) and angiotensin II. The present study demonstrates, however, that depending on prevailing conditions, COX-2-derived prostanoids may also inhibit VSMC proliferation. METHODS AND RESUL...

journal_title：Circulation

authors： Haider A,Lee I,Grabarek J,Darzynkiewicz Z,Ferreri NR

更新日期：2003-08-26 00:00:00

abstract：BACKGROUND:Vascular smooth muscle cell growth factors are postulated to contribute to cardiac allograft vasculopathy (CAV). Few data quantitatively address the timing, location, or stimuli for growth factor expression and relationship to CAV. METHODS AND RESULTS:Acidic fibroblast growth factor (aFGF) mRNA expression w...

journal_title：Circulation

authors： Miller GG,Davis SF,Atkinson JB,Chomsky DB,Pedroso P,Reddy VS,Drinkwater DC,Zhao XM,Pierson RN

更新日期：1999-12-14 00:00:00

abstract：:A study correlating the electrocardiographic findings and the histology of the atrioventricular (AV) conduction system was carried out in 14 cases with chronic complete AV block and in 13 cases without chronic complete AV block. Patients with chronic complete AV block were divided into two groups, based on the width o...

journal_title：Circulation

authors： Ohkawa S,Hackel DB,Ideker RE

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:We measured the content and activities of components of the beta-adrenergic receptor-G protein-adenylate cyclase complex and adrenergic neurotransmitter levels in left and right ventricular myocardial preparations derived from 77 end-stage failing human hearts from patients with idiopathic dilated cardiomyop...

journal_title：Circulation

authors： Bristow MR,Anderson FL,Port JD,Skerl L,Hershberger RE,Larrabee P,O'Connell JB,Renlund DG,Volkman K,Murray J

更新日期：1991-09-01 00:00:00

abstract：:Two-dimensional suprasternal notch echocardiography was performed in 1033 patients, ages 1 day to 18 years. For the long-axis suprasternal notch view, the transducer was positioned in the suprasternal notch and angled to obtain a plane passing between the right nipple and left scapular tip. In this view, the entire ao...

journal_title：Circulation

authors： Snider AR,Silverman NH

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:approximately half of patients with heart failure die suddenly as a result of ventricular arrhythmias. Although abnormal Ca(2+) release from the sarcoplasmic reticulum through ryanodine receptors (RyR2) has been linked to arrhythmogenesis, the molecular mechanisms triggering release of arrhythmogenic Ca(2+) ...

journal_title：Circulation

authors： van Oort RJ,McCauley MD,Dixit SS,Pereira L,Yang Y,Respress JL,Wang Q,De Almeida AC,Skapura DG,Anderson ME,Bers DM,Wehrens XH

更新日期：2010-12-21 00:00:00

abstract：BACKGROUND:Lipoprotein(a) [Lp(a)] may play a causal role in atherosclerosis. PCSK9 (proprotein convertase subtilisin/kexin 9) inhibitors have been shown to significantly reduce plasma Lp(a) concentration. However, the relationship between Lp(a) levels, PCSK9 inhibition, and cardiovascular risk reduction remains undefin...

journal_title：Circulation

authors： O'Donoghue ML,Fazio S,Giugliano RP,Stroes ESG,Kanevsky E,Gouni-Berthold I,Im K,Lira Pineda A,Wasserman SM,Češka R,Ezhov MV,Jukema JW,Jensen HK,Tokgözoğlu SL,Mach F,Huber K,Sever PS,Keech AC,Pedersen TR,Sabatine MS

更新日期：2019-03-19 00:00:00

abstract：:As the appreciation of structural heart disease in children and adults has increased and as catheter-based closure procedures are now being performed in clinical practice, cardiovascular physicians have multiple compelling new reasons to better understand cardiac anatomic and spatial relationships. Current 2-dimension...

journal_title：Circulation

authors： Kim MS,Hansgen AR,Wink O,Quaife RA,Carroll JD

更新日期：2008-05-06 00:00:00

abstract：BACKGROUND:Long-term rapid atrial pacing may result in atrial fibrillation (AF) in dogs. Whether there is histological evidence for neural remodeling is unclear. METHOD AND RESULTS:We performed rapid right atrial pacing in 6 dogs for 111+/-76 days to induce sustained AF. Tissues from 6 healthy dogs were used as contro...

journal_title：Circulation

authors： Chang CM,Wu TJ,Zhou S,Doshi RN,Lee MH,Ohara T,Fishbein MC,Karagueuzian HS,Chen PS,Chen LS

更新日期：2001-01-02 00:00:00

abstract：:The current dispute over the effects of "low" vs "high" doses of aspirin should take into consideration the pharmacokinetics of this drug. In fact, different pharmaceutical formulations of aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in healthy volunteers taking 320 ...

journal_title：Circulation

authors： de Gaetano G,Cerletti C,Dejana E,Latini R

更新日期：1985-12-01 00:00:00

abstract：:A case of progressive pulmonary hypertension in a child with a small ventricular septal defect is presented. Natural history studies have indicated that children with small ventricular septal defects can be followed conservatively. This case represents a contradiction to that rule and suggests that further study must ...

journal_title：Circulation

authors： Bisset GS 3rd,Hirschfeld SS

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Cardiac Na/K-ATPase (NKA) regulates intracellular Na ([Na](i)), which in turn affects intracellular Ca and thus contractility via Na/Ca exchange. Recent evidence shows that phosphorylation of the NKA-associated small transmembrane protein phospholemman (PLM) mediates beta-adrenergic-induced NKA stimulation. ...

journal_title：Circulation

authors： Despa S,Tucker AL,Bers DM

更新日期：2008-04-08 00:00:00