Suprasternal notch echocardiography: a two-dimensional technique for evaluating congenital heart disease.

abstract：BACKGROUND:Angiography of the coronary arteries reflects only changes in luminal dimensions. With intravascular ultrasound, cross-sectional images can be obtained and area measurements can be added to calculate volumes of the external elastic membrane (EEM), plaque plus media (P+M), and lumen. The aim of this study was...

journal_title：Circulation

authors： Jensen LO,Thayssen P,Pedersen KE,Stender S,Haghfelt T

更新日期：2004-07-20 00:00:00

abstract：BACKGROUND:Although early intravenous beta-blocker therapy during acute myocardial infarction (AMI) reduces the incidence of fatal arrhythmias in patients not treated with thrombolytic agents, its antiarrhythmic effect in thrombolysed patients remains controversial. We investigated prospectively the arrhythmia incidenc...

journal_title：Circulation

authors： Heidbüchel H,Tack J,Vanneste L,Ballet A,Ector H,Van de Werf F

更新日期：1994-03-01 00:00:00

abstract：:To assess whether gross pathologic differences exist between hearts with left bundle branch block (LBBB) and left-axis deviation (LAXD) and those with LBBB and a normal frontal plane axis, we examined 70 hearts with LBBB in a series of 1410 sequential dissections (5%). Thirty-two hearts had LAXD and 34 had normal axes...

journal_title：Circulation

authors： Havelda CJ,Sohi GS,Flowers NC,Horan LG

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Whether and to what extent complement is activated in acute myocardial infarction (AMI) and how it contributes to inflammation of the ischemic area are not yet clear. Fibrinolytic agents used for thrombolysis are known to activate complement in vitro and may contribute to its activation in vivo. The aim of t...

journal_title：Circulation

authors： Frangi D,Gardinali M,Conciato L,Cafaro C,Pozzoni L,Agostoni A

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Peripheral arterial disease (PAD) is associated with significant morbidity and mortality and is an important marker of subclinical coronary heart disease. However, estimates of PAD prevalence in the general US population have varied widely. METHODS AND RESULTS:We analyzed data from 2174 participants aged 40...

journal_title：Circulation

authors： Selvin E,Erlinger TP

更新日期：2004-08-10 00:00:00

abstract：:Ventricular septal defects are the most common congenital heart defect. They vary greatly in location, clinical presentation, associated lesions, and natural history. The present article describes the clinical aspects of ventricular septal defects and current management strategies. ...

journal_title：Circulation

authors： Minette MS,Sahn DJ

更新日期：2006-11-14 00:00:00

abstract：:The role of right ventricular (RV) fibrosis in pulmonary hypertension (PH) remains a subject of ongoing discussion. Alterations of the collagen network of the extracellular matrix may help prevent ventricular dilatation in the pressure-overloaded RV. At the same time, fibrosis impairs cardiac function, and a growing b...

journal_title：Circulation

authors： Andersen S,Nielsen-Kudsk JE,Vonk Noordegraaf A,de Man FS

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Electrophysiological mechanisms by which adenosine may activate cardiac afferent neurons are unknown. Slow afterhyperpolarizations (AHPs) follow action potentials in a subset of vagal C afferents, rendering them inexcitable. The purpose of this study was to test the hypothesis that adenosine increases vagal ...

journal_title：Circulation

authors： Middlekauff HR,Doering A,Weiss JN

更新日期：2001-03-06 00:00:00

abstract：BACKGROUND:Fluid energy loss across stenotic aortic valves is influenced by factors other than the valve effective orifice area (EOA). We propose a new index that will provide a more accurate estimate of this energy loss. METHODS AND RESULTS:An experimental model was designed to measure EOA and energy loss in 2 fixed ...

journal_title：Circulation

authors： Garcia D,Pibarot P,Dumesnil JG,Sakr F,Durand LG

更新日期：2000-02-22 00:00:00

abstract：BACKGROUND:Biventricular direct cardiac compression (DCC) can potentially support the failing heart without the complications associated with a blood/device interface. The effect of uniform DCC on left and right ventricular performance was evaluated in 7 isolated canine heart preparations. METHODS AND RESULTS:A comput...

journal_title：Circulation

authors： Artrip JH,Wang J,Leventhal AR,Tsitlik JE,Levin HR,Burkhoff D

更新日期：1999-04-27 00:00:00

abstract：BACKGROUND:Long-term survival after acute kidney injury (AKI) is poorly studied. We report the relationship between long-term mortality and AKI with small changes in serum creatinine during hospitalization after various cardiothoracic surgery procedures. METHODS AND RESULTS:This was a retrospective study of 2973 patie...

journal_title：Circulation

authors： Hobson CE,Yavas S,Segal MS,Schold JD,Tribble CG,Layon AJ,Bihorac A

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:In patients with symptoms of heart failure, elevations in B-type natriuretic peptide (BNP) accurately identify ventricular dysfunction. However, BNP levels are not specific for ventricular dysfunction in patients who do not have overt symptoms of heart failure, suggesting that other cardiac processes such as...

journal_title：Circulation

authors： Bibbins-Domingo K,Ansari M,Schiller NB,Massie B,Whooley MA

更新日期：2003-12-16 00:00:00

abstract：:With the advent of reliable prosthetic valves, the number of aortic valvuloplastic procedures performed in adults has decreased significantly. This is in contradistinction to patients with congenital aortic stenosis, in whom aortic valvuloplasty remains the primary approach. Although only a 25% to 50% incidence of lon...

journal_title：Circulation

authors： Mindich BP,Guarino T,Goldman ME

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:In patients with acute minor ischemic stroke or high-risk transient ischemic attack enrolled in the POINT trial (Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke [POINT] Trial), the combination of clopidogrel and aspirin for 90 days reduced major ischemic events but increased major hemorrhag...

journal_title：Circulation

authors： Johnston SC,Elm JJ,Easton JD,Farrant M,Barsan WG,Kim AS,Lindblad AS,Palesch YY,Zurita KG,Albers GW,Cucchiara BL,Kleindorfer DO,Lutsep HL,Pearson C,Sethi P,Vora N,POINT and Neurological Emergencies Treatment Trials Network

更新日期：2019-08-20 00:00:00

abstract：BACKGROUND:Although previous studies have shown functional improvements in patients who undergo coronary artery bypass graft (CABG) surgery, data are conflicting on whether the gains achieved by women are similar to or less than those achieved by men. METHODS AND RESULTS:We compared physical and psychological function...

journal_title：Circulation

authors： Vaccarino V,Lin ZQ,Kasl SV,Mattera JA,Roumanis SA,Abramson JL,Krumholz HM

更新日期：2003-11-25 00:00:00

abstract：BACKGROUND:Hypertrophic cardiomyopathy (HCM) is diagnosed clinically by the presence of left ventricular hypertrophy (LVH). However, LVH is absent in a significant number of genotype-positive patients. Because myocyte dysfunction and disarray are the primary abnormalities in HCM, we reasoned that tissue Doppler imaging...

journal_title：Circulation

authors： Nagueh SF,Kopelen HA,Lim DS,Zoghbi WA,Quiñones MA,Roberts R,Marian AJ

更新日期：2000-09-19 00:00:00

abstract：BACKGROUND:Cardiomyocyte grafting augments myocyte numbers in the heart. We investigated (1) how developmental stage influences graft survival; (2) whether acutely necrotic or healing cardiac lesions support grafts; and (3) the differentiation and integration of cardiomyocyte grafts in injured hearts. METHODS AND RESU...

journal_title：Circulation

authors： Reinecke H,Zhang M,Bartosek T,Murry CE

更新日期：1999-07-13 00:00:00

abstract：BACKGROUND:The efficacy of bypass surgery in patients with ischemic cardiomyopathy is not easily predictable; preoperative clinical conditions may be similar, but the outcome may differ significantly. We hypothesized that the growth reserve of cardiac stem cells (CSCs) and circulating cytokines promoting CSC activation...

journal_title：Circulation

authors： D'Amario D,Leone AM,Iaconelli A,Luciani N,Gaudino M,Kannappan R,Manchi M,Severino A,Shin SH,Graziani F,Biasillo G,Macchione A,Smaldone C,De Maria GL,Cellini C,Siracusano A,Ottaviani L,Massetti M,Goichberg P,Leri A,

更新日期：2014-01-14 00:00:00

abstract：:Many basic concepts of cardiac output and arterial pressure control have changed considerably in the past few years. In general, each tissue controls its own local resistance and blood flow regardless of the level of arterial pressure; the sum of the local flows then determines the venous return and cardiac output. Ho...

journal_title：Circulation

authors： Guyton AC

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Current guidelines recommend mitral valve surgery for asymptomatic patients with severe degenerative mitral regurgitation and preserved left ventricular systolic function when exercise pulmonary hypertension (PHT) is present. However, the determinants of exercise PHT have not been evaluated. The aim of this ...

journal_title：Circulation

authors： Magne J,Lancellotti P,Piérard LA

更新日期：2010-07-06 00:00:00

abstract：BACKGROUND:Recent findings suggesting the involvement of adventitial cells in coronary repair have raised questions regarding the phenotypic "plasticity" of medial smooth muscle cells (SMCs). Accordingly, the aims of the present study were to examine the characteristics of coronary medial and adventitial cells and to c...

journal_title：Circulation

authors： Patel S,Shi Y,Niculescu R,Chung EH,Martin JL,Zalewski A

更新日期：2000-02-08 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) is associated with endothelial dysfunction including impaired endothelium-mediated, flow-dependent dilation (FDD). There is evidence for increased radical formation in CHF, raising the possibility that nitric oxide is inactivated by radicals, thereby impairing endothelial function...

journal_title：Circulation

authors： Hornig B,Arakawa N,Kohler C,Drexler H

更新日期：1998-02-03 00:00:00

abstract：BACKGROUND:The estrogen receptor-alpha (ER-alpha) IVS1-401 polymorphism identifies a group of women (approximately 20%) who have augmented effects of hormone replacement therapy (HRT) on levels of HDL cholesterol. This study sought to determine if this augmentation extends to HRT regulation of E-selectin and C-reactive...

journal_title：Circulation

authors： Herrington DM,Howard TD,Brosnihan KB,McDonnell DP,Li X,Hawkins GA,Reboussin DM,Xu J,Zheng SL,Meyers DA,Bleecker ER

更新日期：2002-04-23 00:00:00

abstract：BACKGROUND:Hypoxia from birth in immature rabbits increases the tolerance of isolated hearts to ischemia compared with age-matched normoxic rabbits. We determined whether this increased tolerance to ischemia was due to an alteration in the ATP-sensitive potassium (KATP) channel and whether increased KATP channel activa...

journal_title：Circulation

authors： Baker JE,Curry BD,Olinger GN,Gross GJ

更新日期：1997-03-04 00:00:00

abstract：BACKGROUND:Weight loss in obese insulin-resistant but not in insulin-sensitive persons reduces coronary heart disease risk. To what extent changes in gene expression are related to atherosclerosis and cardiovascular function is unknown. METHODS AND RESULTS:We studied the effect of diet restriction-induced weight loss ...

journal_title：Circulation

authors： Verreth W,De Keyzer D,Pelat M,Verhamme P,Ganame J,Bielicki JK,Mertens A,Quarck R,Benhabilès N,Marguerie G,Mackness B,Mackness M,Ninio E,Herregods MC,Balligand JL,Holvoet P

更新日期：2004-11-16 00:00:00

abstract：PURPOSE:The Kantrowitz CardioVAD (KCV) is an electrically powered, pneumatically driven circulatory assist device which provides diastolic augmentation and systolic unloading to the failing heart. It consists of a 60cc-pumping chamber, a percutaneous access device (PAD), and an external controller. The pumping chamber,...

journal_title：Circulation

authors： Jeevanandam V,Jayakar D,Anderson AS,Martin S,Piccione W Jr,Heroux AL,Wynne J,Stephenson LW,Hsu J,Freed PS,Kantrowitz A

更新日期：2002-09-24 00:00:00

abstract：:Although past reports have identified a variety of prognostic factors in patients with severe chronic heart failure, previous studies have not evaluated the interaction of prognostic variables and drug treatment. We analyzed the association of 30 clinical, hemodynamic, and biochemical variables with survival in 203 co...

journal_title：Circulation

authors： Lee WH,Packer M

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Acute cardiac and cerebrovascular accidents are more frequent in hypertensive subjects with a family history of acute vascular accidents. The mechanisms underlying the susceptibility to vascular disease in these subjects are unknown. We investigated whether a parental history of premature heart attack or str...

journal_title：Circulation

authors： Volpe M,Lembo G,De Luca N,Lamenza F,Tritto C,Ricciardelli B,Molaro M,De Campora P,Condorelli G,Rendina V

更新日期：1991-07-01 00:00:00

abstract：:Cardiac allograft vasculopathy (CAV) remains a troublesome long-term complication of heart transplantation. It is manifested by a unique and unusually accelerated form of coronary disease affecting both intramural and epicardial coronary arteries and veins.CAV is characterized by vascular injury induced by a variety o...

journal_title：Circulation

authors： Weis M,von Scheidt W

更新日期：1997-09-16 00:00:00

abstract：:Several conditions that contribute to drowning and near drowning must be considered in the treatment of near-drowned victims. Regardless of the cause, mechanical ventilation should begin as soon as possible and closed-chest cardiac massage should be administered when there is any question about the adequacy of cardiac...

journal_title：Circulation

authors： Modell JH

更新日期：1986-12-01 00:00:00